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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC22A17 Gene

protein-coding   GIFtS: 46
GCID: GC14M023815

solute carrier family 22, member 17
 Explore 5 diseases affiliated with
SLC22A17 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SLC22A17    

Aliases
for SLC22A17 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Solute Carrier Family 22, Member 171 2     NGALR22 5
BOCT1 2 3 5     NGALR32 5
BOIT1 2 3 5     HBOIT1
NGALR1 2 5     NGAL Receptor2
Brain-Type Organic Cation Transporter2 3     Potent Brain Type Organic Ion Transporter2
Lipocalin-2 Receptor2 3     Solute Carrier Family 22 (Organic Cation Transporter), Member 172
Neutrophil Gelatinase-Associated Lipocalin Receptor2 3     Solute Carrier Family 22 Member 172
24p3 Receptor2 3     NgalR3
24p3R2 3     

External Ids:    HGNC: 230951   Entrez Gene: 513102   Ensembl: ENSG000000920967   OMIM: 6114615   UniProtKB: Q8WUG53   

Export aliases for SLC22A17 gene to outside databases

Previous GC identifers: GC14M021805 GC14M022888 GC14M003931


Summaries
for SLC22A17 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: S22AH_HUMAN, Q8WUG5
Function: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind
iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing
intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3),
followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron
chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and
resulting in apoptosis (By similarity)




Genomic Views
for SLC22A17 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC22A17 gene promoter:
         GR   GR-beta   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC22A17 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC22A17

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC22A17


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q11.2   Ensembl cytogenetic band:  14q11.2   HGNC cytogenetic band: 14q11.2

SLC22A17 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC22A17 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M023815:  view genomic region     (about GC identifiers)

Start:
 23,815,515 bp from pter      End:
 23,822,121 bp from pter
Size:
 6,607 bases      Orientation:
 minus strand

Proteins
for SLC22A17 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: S22AH_HUMAN, Q8WUG5 (See protein sequence)
Recommended Name: Solute carrier family 22 member 17  
Size: 538 amino acids; 57686 Da
Subcellular location: Cell membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Note=Upon LCN2-binding, it is internalized
Sequence caution: Sequence=CAC01119.1; Type=Erroneous initiation; Sequence=CAC17762.1; Type=Erroneous initiation;
Secondary accessions: A4UA13 A8MUT0 Q2TAB0 Q5BKY8 Q86U04 Q9H1D3 Q9NQD5
Alternative splicing: 3 isoforms:  Q8WUG5-1   Q8WUG5-2   Q8WUG5-3   

Explore the universe of human proteins at neXtProt for SLC22A17: NX_Q8WUG5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8WUG5

    • SLC22A17 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_057693.3  NP_065105.2  

    ENSEMBL proteins: 
     ENSP00000346824   ENSP00000380430   ENSP00000206544   ENSP00000380437  

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    Novus Biologicals SLC22A17 Proteins
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    Uscn Proteins for SLC22A17

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005774vacuolar membrane IEA--
    GO:0005887integral to plasma membrane IDA17253959
    GO:0016021integral to membrane ----
    GO:0031301integral to organelle membrane IDA17253959


    SLC22A17 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for SLC22A17 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC22A17 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR005829 Sugar_transporter_CS
     IPR005828 Sub_transporter
     IPR020846 MFS_dom
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry Q8WUG5

    ProtoNet protein and cluster: Q8WUG5

    UniProtKB/Swiss-Prot: S22AH_HUMAN, Q8WUG5
    Similarity: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family


    Function
    for SLC22A17 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: S22AH_HUMAN, Q8WUG5
    Function: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind
    iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing
    intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3),
    followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron
    chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and
    resulting in apoptosis (By similarity)
    Induction: Expression is activated by RUNX3. Repressed by the oncoprotein BCR-ABL; BCR-ABL misregulates expression by
    inducing a switch in binding from RUNX3 to RUNX1, a repressor of 24p3R expression, through a Ras signaling pathway

    miRNA
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    hsa-miR-4303 hsa-miR-1321 hsa-miR-3194-5p hsa-miR-15a hsa-miR-4297 hsa-miR-765 hsa-miR-497 hsa-miR-339-5p
    SwitchGear 3'UTR luciferase reporter plasmid: SLC22A17 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004888transmembrane signaling receptor activity ISS--
    GO:0005515protein binding ----
    GO:0022857transmembrane transporter activity IEA--


    SLC22A17 for ontologies           About GeneDecksing



    Pathways & Interactions
    for SLC22A17 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SLC22A17

    1 Interacting protein for SLC22A17 (Q8WUG53) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LCN2P801883I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport IEA--
    GO:0015891siderophore transport ISS--


    SLC22A17 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC22A17 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC22A17
    Search CenterWatch for drugs/clinical trials and news about SLC22A17 / S22AH 

    Transcripts
    for SLC22A17 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SLC22A17 gene (2 alternative transcripts): 
    NM_016609.3  NM_020372.2  

    Unigene Cluster for SLC22A17:

    Solute carrier family 22, member 17
    Hs.373498  [show with all ESTs]
    Unigene Representative Sequence: BX161416
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000354772(uc001wjm.3) ENST00000397260 ENST00000474057(uc001wjn.3)
    ENST00000206544(uc001wjl.3 uc010akk.3) ENST00000473917 ENST00000474774
    ENST00000557699(uc010akl.1) ENST00000556803 ENST00000397267

    miRNA
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    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC22A17 (see all 15):
    hsa-miR-4303 hsa-miR-1321 hsa-miR-3194-5p hsa-miR-15a hsa-miR-4297 hsa-miR-765 hsa-miR-497 hsa-miR-339-5p
    SwitchGear 3'UTR luciferase reporter plasmid: SLC22A17 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC22A17 (see all 7)
    OriGene shRNA RFP: SLC22A17
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    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC22A17
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    Additional cDNA sequence: 

    AJ243653.1 AK308661.1 AK311241.1 BC020565.1 BC030559.1 BC090870.1 BC111015.1 BX161416.1 
    BX647316.1 DQ658848.1 

    14 DOTS entries:

    DT.91730294  DT.445029  DT.100788029  DT.95329077  DT.100778882  DT.100809449  DT.97845195  DT.100756795 
    DT.100676553  DT.95329079  DT.100650402  DT.100778885  DT.86854003  DT.75171847 

    24/213 AceView cDNA sequences (see all 213):

    BC020565 AI479999 AI969180 AI955123 AW191855 CK823850 AI955335 H49989 
    BU732373 BI523486 AI202756 BQ447129 NM_020372 BM709232 CR607061 BF525613 
    CB241321 CA487527 CK823849 BM804127 AI754329 CF453867 BM729312 BG819749 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for SLC22A17 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c · 10d ^ 11a · 11b ^ 12
    SP1:                                            -                                                                                 
    SP2:                                            -                                                           -                     
    SP3:                                                                                -                       -                     
    SP4:                    -                       -                                                                                 
    SP5:                                            -                                                                                 


    ECgene alternative splicing isoforms for SLC22A17

    Expression
    for SLC22A17 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC22A17 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAGCCTTCCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SLC22A17 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainChoroid PlexusMature Choroid Plexus CellsChoroid Plexus
    EyeInner Nuclear LayerGABAergic Amacrine CellsAmacrine, Retina
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    PureStem™ mesenchymal progenitor MEL2 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ mesenchymal progenitor 7SMOO32 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage

    See SLC22A17 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC22A17

    SOURCE GeneReport for Unigene cluster: Hs.373498

    UniProtKB/Swiss-Prot: S22AH_HUMAN, Q8WUG5
    Tissue specificity: Expressed in brain

        SABiosciences Custom PCR Arrays for SLC22A17
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    In Situ
    Assay Products:     
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    Orthologs
    for SLC22A17 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for SLC22A17 gene from 4/16 species (see all 16)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    lizard
    (Anolis carolinensis)    		 Reptilia SLC22A176
    		 --
    		 41(a)
    		 1 ↔ 1
    		 GL343680.1(226616-246142)
    zebrafish
    (Danio rerio)    		 Actinopterygii LOC1003299051 solute carrier family 22 member 17-like 53.72(n)
    45.49(a)    		   100329905  XM_002666734.1  XP_002666780.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG44656
    CG60066
    (see all 6)    		 --
    		 9(a)
    15(a)
    (see all 6)    		 possible ortholog
    many ↔ many
    (see all 6)    		 3R(15741590-15743561)
    3R(11981040-11997488)
    worm
    (Caenorhabditis elegans)    		 Secernentea K05F1.66
    B0252.36
    (see all 24)    		 Putative transporter B0252.3
    (see all 24)    		 9(a)
    17(a)
    (see all 24)    		 possible ortholog
    possible ortholog
    (see all 24)    		 II(5782537-5787635)
    II(6902826-6907713)


    ENSEMBL Gene Tree for SLC22A17 (if available)
    TreeFam Gene Tree for SLC22A17 (if available) 

    Paralogs
    for SLC22A17 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC22A17 gene
    SLC22A232  
    3 SIMAP similar genes for SLC22A17 using alignment to 2 protein entries:     S22AH_HUMAN (see all proteins):
    DKFZp434F011    SLC22A23    SLC22A31

    SLC22A17 for paralogs           About GeneDecksing



    Genomic Variants
    for SLC22A17 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/158 NCBI SNPs in SLC22A17 are shown (see all 158)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 14 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1860593191,2
    		--23815052(+) ATCTAA/GAAGAA 2 -- ds5001 int10--------
    rs118444961,2
    		C,F,H,--23815109(+) TTCTCC/GGCTCC 2 -- ds5001 int19Minor allele frequency- G:0.04NS EA NA CSA WA 770
    rs1892602971,2
    		--23815133(+) TACGAC/TGAGTT 2 -- ds5001 int10--------
    rs1158563281,2
    		--23815199(+) AATTCC/TCTTTT 2 -- ds5001 int11Minor allele frequency- T:0.01WA 118
    rs711190201,2
    		C,--23815248(+) CAACA-/AACAACAA 2 -- int1 ds50011Minor allele frequency- AAC:0.00NA 2
    rs714250871,2
    		C--23815250(+) AACAACAA/-CAACA 2 -- int1 ds50011Minor allele frequency- -:0.50NA 2
    rs1179715661,2
    		F,--23815326(+) TGATAC/TGAAGT 2 -- ds5001 int11Minor allele frequency- T:0.03NA 120
    rs1395247451,2
    		--23815335(+) GTGTGC/TCAAGT 2 -- ds5001 int10--------
    rs736024991,2
    		C,--23815374(+) GCAGTC/TAGTAA 2 -- ds5001 int12Minor allele frequency- T:0.04WA 120
    rs101301181,2
    		C,F,A,H,--23815409(+) CCACTC/GGGGGC 2 -- ds5001 int119Minor allele frequency- G:0.34NA NS EA WA CSA 929

    HapMap Linkage Disequilibrium report for SLC22A17 (23815515 - 23822121 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SLC22A17: --

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    Disorders / Diseases
    for SLC22A17 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC22A17 for disorders           About GeneDecksing

    OMIM gene information: 611461    OMIM disorders: --

    5 diseases for SLC22A17:    About MalaCards
    esophageal squamous cell carcinoma    squamous cell carcinoma    endometrial carcinoma    esophagitis
    carcinoma


    Export disorders for SLC22A17 gene to outside databases

    Publications
    for SLC22A17 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC22A17 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with SLC22A17)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake. (PubMed id 16377569)1, 2, 3 Devireddy L.R....Green M.R. (2005)
    2. A novel alternative spliced variant of neutrophil gelatinase- associated lipocalin receptor in oesophageal carcinoma cells. (PubMed id 17253959)1, 2 Fang W.K.... Li E.M. (2007)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. [Correlation of lipocalin-2 and its receptor expressio ns with preeclampsia]. (PubMed id 22932106)1 Cao W.H....Ye Y.H. (2012)
    5. NGAL and NGALR overexpression in human hepatocellular carcinoma toward a molecular prognostic classification. (PubMed id 22728279)1 Zhang Y....Mei Z. (2012)
    6. Immunohistochemical detection of a specific receptor for lipocalin2 (solute carrier family 22 member 17, SLC22A17) and its prognosti c significance in endometrial carcinoma. (PubMed id 21763306)1 Miyamoto T....Shiozawa T. (2011)
    7. NGAL and NGALR are frequently overexpressed in human gliomas and are associated with clinical prognosis. (PubMed id 21184133)1 Liu M.F....Xu H.X. (2011)
    8. Increased expression of neutrophil gelatinase-associa ted lipocalin receptor by interleukin-1I^ in human mesangial cells via MAPK/ERK activation. (PubMed id 21305251)1 Mao S....Zhang N. (2011)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)

    External Searches for SLC22A17 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
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    OMIM
    NCBI Bookshelf
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    Genome Databases showing SLC22A17 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51310 HGNC: 23095 AceView: SLC22A17 Ensembl:ENSG00000092096 euGenes: HUgn51310
    ECgene: SLC22A17 H-InvDB: SLC22A17

    Other Databases showing SLC22A17 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SLC22A17 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC22A17 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC22A17 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC22A17 gene:
    Search GeneIP for patents involving SLC22A17

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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