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SLC22A15 Gene

protein-coding   GIFtS: 53
GCID: GC01P116520

Solute Carrier Family 22, Member 15

(Previous names: solute carrier family 22 (organic cation transporter), member...)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 22, Member 151 2     PRO346862
FLIPT12 3 5     Fly-Like Putative Organic Ion Transporter 12
Solute Carrier Family 22 (Organic Cation Transporter), Member 151 2     Solute Carrier Family 22 Member 152
Flipt 12 3     Trans-Like Protein2
Fly-Like Putative Transporter 12 3     

External Ids:    HGNC: 203011   Entrez Gene: 553562   Ensembl: ENSG000001633937   OMIM: 6082755   UniProtKB: Q8IZD63   

Export aliases for SLC22A15 gene to outside databases

Previous GC identifers: GC01P115666 GC01P115865 GC01P116231 GC01P114392


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC22A15 Gene:
Organic ion transporters, such as SLC22A15, transport various medically and physiologically important compounds,
including pharmaceuticals, toxins, hormones, neurotransmitters, and cellular metabolites. These transporters are
also referred to as amphiphilic solute facilitators (ASFs).(supplied by OMIM, Apr 2004)

GeneCards Summary for SLC22A15 Gene:
SLC22A15 (solute carrier family 22, member 15) is a protein-coding gene. GO annotations related to this gene include transmembrane transporter activity. An important paralog of this gene is SLC22A11.

UniProtKB/Swiss-Prot: S22AF_HUMAN, Q8IZD6
Function: Probably transports organic cations (By similarity). Appears not to be the agmatine transporter




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC22A15 gene promoter:
         LHX3b/Lhx3b   C/EBPbeta   Pbx1a   GCNF   Evi-1   GATA-1   HEN1   GCNF-1   LHX3a/Lhx3a   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC22A15 promoter sequence
   Search Chromatin IP Primers for SLC22A15

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC22A15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p13.1   Ensembl cytogenetic band:  1p13.1   HGNC cytogenetic band: 1p12

SLC22A15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC22A15 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P116520:  view genomic region     (about GC identifiers)

Start:
116,519,119 bp from pter      End:
116,612,675 bp from pter
Size:
93,557 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: S22AF_HUMAN, Q8IZD6 (See protein sequence)
Recommended Name: Solute carrier family 22 member 15  
Size: 547 amino acids; 60540 Da
Developmental stage: Expressed at low levels at 20-25 weeks of gestation in fetal brain, lung, liver and kidney
Sequence caution: Sequence=AAH26358.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAH26358.1; Type=Frameshift; Positions=7;
Secondary accessions: A8MUR3 Q6UXP5 Q8TAL9 Q9NSH5
Alternative splicing: 2 isoforms:  Q8IZD6-1   Q8IZD6-2   

Explore the universe of human proteins at neXtProt for SLC22A15: NX_Q8IZD6

Explore proteomics data for SLC22A15 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn58, Asn63, Asn80, Asn106
  • Modification sites at PhosphoSitePlus

  • See SLC22A15 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060890.2  
    ENSEMBL proteins: 
     ENSP00000358515   ENSP00000358514  
    Reactome Protein details: Q8IZD6

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    Cloud-Clone Corp. Proteins for SLC22A15

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Fly-like putative transporter 1
    Orphan or poorly characterized SLC22 family members

    3 InterPro protein domains:
     IPR005828 Sub_transporter
     IPR020846 MFS_dom
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry Q8IZD6

    ProtoNet protein and cluster: Q8IZD6

    UniProtKB/Swiss-Prot: S22AF_HUMAN, Q8IZD6
    Similarity: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19)
    family


    Find genes that share domains with SLC22A15           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S22AF_HUMAN, Q8IZD6
    Function: Probably transports organic cations (By similarity). Appears not to be the agmatine transporter

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0022857transmembrane transporter activity IEA--
         
    Find genes that share ontologies with SLC22A15           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SLC22A15:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC22A15
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    miRNA
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    miRTarBase miRNAs that target SLC22A15:
    hsa-mir-335-5p (MIRT017359)

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    Selected qRT-PCR Assays for microRNAs that regulate SLC22A15 (see all 26):
    hsa-miR-4307 hsa-miR-200a hsa-miR-216b hsa-miR-520a-5p hsa-miR-570 hsa-miR-141 hsa-miR-515-5p hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidSLC22A15 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    S22AF_HUMAN, Q8IZD6: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    lysosome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with SLC22A15           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SLC22A15 About    
    See pathways by source

    SuperPathContained pathways About
    1Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    SLC-mediated transmembrane transport0.47
    Organic cation/anion/zwitterion transport0.00
    Transmembrane transport of small molecules0.47
    Organic cation transport0.00
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38


    Find genes that share SuperPaths with SLC22A15           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for SLC22A15
        Organic cation transport


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC22A15
    Interactions:

        Search GeneGlobe Interaction Network for SLC22A15

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for SLC22A15 (ENSP000003585154) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATG4AENSP000003613064STRING: ENSP00000361306
    ATG4BENSP000003842594STRING: ENSP00000384259
    SIL1ENSP000002651954STRING: ENSP00000265195
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport IEA--
    GO:0055085transmembrane transport ----

    Find genes that share ontologies with SLC22A15           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC22A15 (S22AF)

    1 HMDB Compound for SLC22A15    About this table
    CompoundSynonyms CAS #PubMed Ids
    Agmatine(4-Aminobutyl)guanidine (see all 11)306-60-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SLC22A15 gene: 
    NM_018420.2  

    Unigene Cluster for SLC22A15:

    Solute carrier family 22, member 15
    Hs.125482  [show with all ESTs]
    Unigene Representative Sequence: NM_018420
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369503(uc001egb.4) ENST00000369502(uc001ega.2) ENST00000481127

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SLC22A15 (see all 26):
    hsa-miR-4307 hsa-miR-200a hsa-miR-216b hsa-miR-520a-5p hsa-miR-570 hsa-miR-141 hsa-miR-515-5p hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidSLC22A15 3' UTR sequence
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    Additional mRNA sequence: 

    AK055633.1 AK125072.1 AL353933.1 AY145501.1 AY358258.1 BC026358.1 BC030090.1 BC070033.1 

    3 DOTS entries:

    DT.97837572  DT.101979439  DT.92065601 

    Selected AceView cDNA sequences (see all 53):

    AI671635 BM678048 BM725943 BX646765 BI753243 CK822879 BQ102269 AK125072 
    BF510438 AY358258 BG577123 AI694746 AA348400 CA489135 AL353933 AK055633 
    BC070033 BQ086157 BI963997 BI963731 AA322865 R16144 BF447813 AI086576 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for SLC22A15    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
    SP1:                                                  -                                       
    SP2:                                      -                                                   


    ECgene alternative splicing isoforms for SLC22A15

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC22A15 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGAAATTTT
    SLC22A15 Expression
    About this image


    SLC22A15 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
    SLC22A15 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC22A15 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.125482

    UniProtKB/Swiss-Prot: S22AF_HUMAN, Q8IZD6
    Tissue specificity: Expressed at highest levels in kidney and brain. Expressed at high levels in skeletal muscle,
    heart, liver, placenta and white blood cells. Expressed at moderate levels in lung and spleen. Expressed at low
    levels in thymus, small intestine and colon. Expressed in several intestinal tumor cell lines

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SLC22A15 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc22a151 , 5 solute carrier family 22 (organic anion/cation transporter), more1, 5 87.99(n)1
    94.12(a)1
      3 (44.30 cM)5
    2421261  NM_001039371.21  NP_001034460.21 
     1018589545 
    chicken
    (Gallus gallus)
    Aves SLC22A151 solute carrier family 22, member 15 79.43(n)
    86.63(a)
      418336  XM_416558.4  XP_416558.2 
    lizard
    (Anolis carolinensis)
    Reptilia SLC22A156
    solute carrier family 22, member 15
    80(a)
    1 ↔ 1
    2(83059586-83085366)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC532522 similar to fly-like putative organic ion transporter more 69.74(n)    BC045234.1 
    zebrafish
    (Danio rerio)
    Actinopterygii SLC22A156
    solute carrier family 22, member 15
    47(a)
    1 ↔ 1
    17(19329310-19341359) ENSDARG00000055445
    fruit fly
    (Drosophila melanogaster)
    Insecta Orct6
    Orct26
    (see all 5)
    Organic cation transporter 2
    (see all 5)
    31(a)
    29(a)
    (see all 5)
    1 ↔ many
    1 ↔ many
    (see all 5)
    3R(20101982-20104515)
    3R(20098753-20101013)
    worm
    (Caenorhabditis elegans)
    Secernentea Y82E9BR.166
    oct-16
    (see all 3)
    Protein Y82E9BR.16, isoform a
    Protein OCT-1, isoform b (oct-1) mRNA, complete cd...
    (see all 3)
    25(a)
    24(a)
    (see all 3)
    1 ↔ many
    1 ↔ many
    (see all 3)
    III(1419865-1427226) WBGene00022348
    I(9888357-9892223) WBGene00003842


    ENSEMBL Gene Tree for SLC22A15 (if available)
    TreeFam Gene Tree for SLC22A15 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC22A15 gene
    SLC22A112  SLC22A52  SLC22A82  SLC22A12  SLC22A242  SLC22A42  SLC22A22  SLC22A102  
    SLC22A132  SLC22A92  SLC22A62  SLC22A122  SLC22A72  SLC22A162  SLC22A32  SLC22A252  
    7 SIMAP similar genes for SLC22A15 using alignment to 1 protein entry:     S22AF_HUMAN:
    SLC22A13    SLC22A5    SLC22A4    SLC22A3    SLC22A16    SLC22A7
    SLC22A8

    Find genes that share paralogs with SLC22A15           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC22A15 (see all 1742)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs359864641,2
    C--116517280(+) AAAGT-/AAAAAA 1 -- us2k10--------
    rs1904067481,2
    --116517308(+) CATATA/GATCAA 1 -- us2k10--------
    rs120676741,2
    C,H--116517365(+) caaacC/Gtctgg 1 -- us2k16Minor allele frequency- G:0.02NS EA WA NA 656
    rs1816383891,2
    --116517396(+) CAATAA/CAGATG 1 -- us2k10--------
    rs12816941,2
    C--116517473(-) gttcaC/Tattgt 1 -- us2k1 tfbs311Minor allele frequency- T:0.02NA WA CSA EA 372
    rs1846060081,2
    --116517649(+) AACAAC/GCTAAG 1 -- us2k10--------
    rs1464592891,2
    --116517841(+) TAGCAA/TTATCG 1 -- us2k10--------
    rs1397878631,2
    --116517919(+) CCGATC/TATCAG 1 -- us2k10--------
    rs1885763781,2
    --116518041(+) TTTAAA/GCTATT 1 -- us2k10--------
    rs1398966881,2
    C--116518075(+) TTCCT-/TAAG  
            
    TAAGA
    1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SLC22A15 (116519119 - 116612675 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for SLC22A15:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv2522CNV Insertion18451855
    nsv528884CNV Loss19592680
    esv27976CNV Loss19812545
    nsv831126CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC22A15
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC22A15

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608275    OMIM disorders: --


    Find genes that share disorders with SLC22A15           About GenesLikeMe

    Genetic Association Database (GAD): SLC22A15
    Human Genome Epidemiology (HuGE) Navigator: SLC22A15 (1 document)

    Export disorders for SLC22A15 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC22A15 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with SLC22A15)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters. (PubMed id 12372408)1, 2, 3 Eraly S.A. and Nigam S.K. (Biochem. Biophys. Res. Commun. 2002)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    4. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (Nature 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. Identification and pharmacological characterization of a specific agmatine transport system in human tumor cell lines. (PubMed id 15028572)2 Molderings G.J.... Gothert M. (Ann. N. Y. Acad. Sci. 2003)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55356 HGNC: 20301 AceView: SLC22A15 Ensembl:ENSG00000163393 euGenes: HUgn55356
    ECgene: SLC22A15 H-InvDB: SLC22A15

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SLC22A15 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC22A15 gene:
    Search GeneIP for patents involving SLC22A15

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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