Aliases for SLC22A11 Gene
External Ids for SLC22A11 Gene
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. [provided by RefSeq, Jul 2008]
GeneCards Summary for SLC22A11 Gene
SLC22A11 (Solute Carrier Family 22 (Organic Anion/Urate Transporter), Member 11) is a Protein Coding gene. Diseases associated with SLC22A11 include cardiovascular disease risk factor. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include inorganic anion exchanger activity and sodium-independent organic anion transmembrane transporter activity. An important paralog of this gene is SLC22A12.
UniProtKB/Swiss-Prot for SLC22A11 Gene
Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds.