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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC22A11 Gene

protein-coding   GIFtS: 59
GCID: GC11P064324

solute carrier family 22 (organic anion/urate transporter),...
 Explore 5 diseases affiliated with
SLC22A11 via
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 Human Malady Compendium 
Biological research products
for SLC22A11    

Aliases
for SLC22A11 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Solute Carrier Family 22 (Organic Anion/Urate Transporter), Member 111 2
OAT41 2 3 5
Organic Anion Transporter 42 3
HOAT41
Solute Carrier Family 22 (Organic Anion/Cation Transporter), Member 112
Solute Carrier Family 22 Member 112

External Ids:    HGNC: 181201   Entrez Gene: 558672   Ensembl: ENSG000001680657   OMIM: 6070975   UniProtKB: Q9NSA03   

Export aliases for SLC22A11 gene to outside databases

Previous GC identifers: GC11P066839 GC11P066004 GC11P064573 GC11P064098 GC11P064079 GC11P060650


Summaries
for SLC22A11 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SLC22A11:
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some
of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney
and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. (provided
by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: S22AB_HUMAN, Q9NSA0
Function: Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds

Gene Wiki entry for SLC22A11


Genomic Views
for SLC22A11 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC22A11 gene promoter:
         Tal-1   p53   Lmo2   MIF-1   Tal-1beta   E47   PPAR-gamma1   PPAR-gamma2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC22A11 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC22A11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC22A11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.1   Ensembl cytogenetic band:  11q13.1   HGNC cytogenetic band: 11q13.3

SLC22A11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC22A11 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P064324:  view genomic region     (about GC identifiers)

Start:
 64,323,098 bp from pter      End:
 64,340,347 bp from pter
Size:
 17,250 bases      Orientation:
 plus strand

Proteins
for SLC22A11 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: S22AB_HUMAN, Q9NSA0 (See protein sequence)
Recommended Name: Solute carrier family 22 member 11  
Size: 550 amino acids; 59972 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence caution: Sequence=BAC11483.1; Type=Erroneous initiation;
Secondary accessions: A8K426 Q53GR2 Q6ZP72 Q8NBU4
Alternative splicing: 2 isoforms:  Q9NSA0-1   Q9NSA0-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC22A11: NX_Q9NSA0

Post-translational modifications:

  • N-glycosylated. Contains several complex-type N-glycans1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NSA0

    • SLC22A11 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_060954.1  
    ENSEMBL proteins: 
     ENSP00000301891   ENSP00000366809   ENSP00000366804   ENSP00000394043   ENSP00000413508  
    Reactome Protein details: Q9NSA0
    Human Recombinant Protein Products: 
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    Uscn Proteins for SLC22A11

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane IDA10660625
    GO:0009897external side of plasma membrane IDA15102942
    GO:0016021integral to membrane ----
    GO:0016324apical plasma membrane IDA15037815


    SLC22A11 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for SLC22A11

    Protein Domains /
    Families
    for SLC22A11 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC22A11 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR005828 Sub_transporter
     IPR020846 MFS_dom
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry Q9NSA0

    ProtoNet protein and cluster: Q9NSA0

    UniProtKB/Swiss-Prot: S22AB_HUMAN, Q9NSA0
    Similarity: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family


    Function
    for SLC22A11 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: S22AB_HUMAN, Q9NSA0
    Function: Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds

    miRNA
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    In Situ Assay
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005452inorganic anion exchanger activity IDA15037815
    GO:0005515protein binding IPI16236806
    GO:0008514organic anion transmembrane transporter activity IDA15291761
    GO:0015347sodium-independent organic anion transmembrane transporter activity IDA10660625
    GO:0022857transmembrane transporter activity ----


    SLC22A11 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SLC22A11:
     Decreased viability with pacli 


    Pathways & Interactions
    for SLC22A11 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1SLC-mediated transmembrane transport
    		SLC-mediated transmembrane transport1.00
    		Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    		Transmembrane transport of small molecules0.50
    2Organic cation/anion/zwitterion transport
    		Organic cation/anion/zwitterion transport1.00
    		Organic anion transport0.38
    3Zidovudine Pathway, Pharmacokinetics/Pharmacodynamics
    		Zidovudine Pathway, Pharmacokinetics/Pharmacodynamics1.00
    4Antimetabolite Pathway - Folate Cycle, Pharmacodynamics
    		Methotrexate Pathway (Cancer Cell), Pharmacodynamics0.45

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5        Reactome Pathways for SLC22A11
        SLC-mediated transmembrane transport
    Transmembrane transport of small molecules
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    Organic cation/anion/zwitterion transport
    Organic anion transport

    2 PharmGKB Pathways for SLC22A11
        Methotrexate Pathway (Cancer Cell), Pharmacodynamics
    Zidovudine Pathway, Pharmacokinetics/Pharmacodynamics


    SLC22A11 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SLC22A11

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for SLC22A11 (Q9NSA03 ENSP000003018914) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CAV3P565393, ENSP000003419404I2D: score=1 STRING: ENSP00000341940
    SLC9A3R1O147453, ENSP000002626134I2D: score=1 STRING: ENSP00000262613
    PDZK1Q5T2W13, ENSP000003421434I2D: score=1 STRING: ENSP00000342143
    RRP1BQ146843, ENSP000003391454I2D: score=1 STRING: ENSP00000339145
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015711organic anion transport IDA10660625
    GO:0046415urate metabolic process IMP19503597
    GO:0055085transmembrane transport TAS--


    SLC22A11 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC22A11 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC22A11 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC22A11

    10/32 DrugBank Compounds for SLC22A11 (see all 32)    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    ProbenecidProbenecid Acid (see all 2)57-66-9targetinhibitor12023506 15377641 12130730 12063169
    transporterinhibitor12023506 15377641 12130730 12063169 12023506 14978359 12130730 12063169
    IndomethacinIMN (see all 9)53-86-1transporterinhibitor10660625 12130730 12063169
    AminohippurateAminohippurate Sodium (see all 7)94-16-6transportersubstrate inhibitor10660625 12063169
    IbuprofenIbuprophen (see all 3)15687-27-1transporterinhibitor10660625 12130730
    Penicillin G-- 61-33-6transporterinhibitor12130730 12063169
    Piroxicam-- 36322-90-4transporterinhibitor12130730 12063169
    Aspartame1-Methyl N-L-alpha-aspartyl-L-phenylalanate (see all 17)22839-47-0transporterinhibitor12063169
    BumetanideBumetanida [INN-Spanish] (see all 2)28395-03-1transporterinhibitor10660625
    Caprylic acidcapryloate (see all 14)124-07-2transporterinhibitor12063169
    CefalotinCefalothin (see all 9)153-61-7transporterinhibitor11909604

    2 Novoseek chemical compound relationships for SLC22A11 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    estrone sulfate 88 4 18414001 (2), 17020956 (1)
    probenecid 72.8 1 15377641 (1)

    Search CenterWatch for drugs/clinical trials and news about SLC22A11 / S22AB 

    Transcripts
    for SLC22A11 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SLC22A11 gene: 
    NM_018484.2  

    Unigene Cluster for SLC22A11:

    Solute carrier family 22 (organic anion/urate transporter), member 11
    Hs.220844  [show with all ESTs]
    Unigene Representative Sequence: NM_018484
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000301891(uc001oai.3 uc009ypq.3) ENST00000377585 ENST00000377581
    ENST00000478051(uc001oah.1) ENST00000490834 ENST00000460745(uc001oak.1)
    ENST00000428570 ENST00000416590

    miRNA
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    Inhib. RNA
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    Additional cDNA sequence: 

    AB026116.1 AK075127.1 AK075224.1 AK129930.1 AK222869.1 AK290791.1 AK296083.1 AK309931.1 
    BC034384.1 

    10 DOTS entries:

    DT.432977  DT.40237838  DT.100835357  DT.100685067  DT.100809906  DT.92047748  DT.100709779  DT.91771309 
    DT.95369012  DT.120751886 

    24/88 AceView cDNA sequences (see all 88):

    CR598571 AK129930 BF995387 BX387248 AK075224 CR605725 BF990361 NM_018484 
    BC034384 BG002010 AB026116 CR608154 BI759874 AA886432 BX396736 BX378031 
    BX338385 BX396735 BX379691 N54154 CD629303 BX381720 AK075127 BX380047 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SLC22A11 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8a · 8b ^ 9 ^ 10 ^ 11
    SP1:                    -                                               -     -           -                     
    SP2:                    -                                               -     -     -     -     -               
    SP3:                    -     -                       -     -                                                   
    SP4:                                                                                                            
    SP5:                                                                                                            


    ECgene alternative splicing isoforms for SLC22A11

    Expression
    for SLC22A11 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC22A11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCTTTACACC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SLC22A11 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Syncytiotrophoblast-like cells (Generation of syncyt...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See SLC22A11 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC22A11

    SOURCE GeneReport for Unigene cluster: Hs.220844

    UniProtKB/Swiss-Prot: S22AB_HUMAN, Q9NSA0
    Tissue specificity: Detected in placenta and kidney

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    In Situ
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    Orthologs
    for SLC22A11 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for SLC22A11 gene from 3/12 species (see all 12)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    zebrafish
    (Danio rerio)    		 Actinopterygii CU638714.26
    		 --
    		 30(a)
    		 possible ortholog
    		 24(20432232-20434293)
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG86543 organic cation porter 33(a)   56F6   --
    worm
    (Caenorhabditis elegans)    		 Secernentea ZK455.8a3 membrane transporter 29(a)
    (best of 3)    		   X(11381686-11385364)   --


    ENSEMBL Gene Tree for SLC22A11 (if available)
    TreeFam Gene Tree for SLC22A11 (if available) 

    Paralogs
    for SLC22A11 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC22A11 gene
    SLC22A52  SLC22A82  SLC22A12  SLC22A242  SLC22A42  SLC22A92  SLC22A22  SLC22A102  
    SLC22A132  SLC22A62  SLC22A152  SLC22A72  SLC22A122  SLC22A32  SLC22A162  SLC22A252  
    18/19 SIMAP similar genes for SLC22A11 using alignment to 4 protein entries:     S22AB_HUMAN (see all proteins) (see all similar genes):
    SLC22A12    HMFN2567    SLC22A10    SLC22A25    UST6    SLC22A24
    OAT7    SLC22A9    SLC22A6    SLC22A8    SLC22A20    SLC22A13
    SLC22A7    SLC22A1    SLC22A5    SLC22A2    SLC22A3    SLC22A4

    SLC22A11 for paralogs           About GeneDecksing



    Genomic Variants
    for SLC22A11 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/325 NCBI SNPs in SLC22A11 are shown (see all 325)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 11 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs777353751,2
    		F,--64321110(+) CAGTTC/TCAGGT 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1142729271,2
    		F,--64321159(+) CCCCAA/GGCAGC 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1911137491,2
    		--64321310(+) AAAGGA/GCAGGG 1 -- us2k10--------
    rs1473307661,2
    		--64321345(+) TGGACA/GGAGGA 1 -- us2k10--------
    rs1406726781,2
    		--64321391(+) GATTCC/TGGCAG 1 -- us2k10--------
    rs1170770751,2
    		F,--64321430(+) AAGGCC/TCGGGC 1 -- us2k11Minor allele frequency- T:0.04NA 120
    rs1446220901,2
    		--64321473(+) TAAAAC/TGTGCA 1 -- us2k10--------
    rs1478896751,2
    		--64321513(+) CGCTCA/CAGAAA 1 -- us2k10--------
    rs1827120451,2
    		--64321531(+) CTAGCC/TAGCAC 1 -- us2k10--------
    rs1861712641,2
    		--64321720(+) TTGCAC/TGTTAG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SLC22A11 (64323098 - 64340347 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for SLC22A11
         2 CNVs: 4752 5422
    Human Gene Mutation Database (HGMD): SLC22A11

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    Disorders / Diseases
    for SLC22A11 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC22A11 for disorders           About GeneDecksing

    OMIM gene information: 607097    OMIM disorders: --

    5 diseases for SLC22A11:    About MalaCards
    metastasis efficiency    gout    osteoporosis    nephropathy
    breast cancer

    1 disease from the University of Copenhagen DISEASES database for SLC22A11:
    Hyperuricemia
    Human Genome Epidemiology (HuGE) Navigator: SLC22A11 (9 documents)

    Export disorders for SLC22A11 gene to outside databases

    Publications
    for SLC22A11 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC22A11 gene, integrated from 9 sources (see all 44):
    (articles sorted by number of sources associating them with SLC22A11)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. (PubMed id 10660625)1, 2, 3, 7 Cha S.H.... Endou H. (2000)
    2. The role of N-linked glycosylation in protein folding, membrane targeting, and substrate binding of human organic anion transporter hOAT4. (PubMed id 15576633)1, 2, 3 Zhou F....You G. (2005)
    3. Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins. (PubMed id 11907186)1, 7, 9 Kimura H.... Endou H. (2002)
    4. Human organic anion transporters mediate the transport of tetracycline. (PubMed id 11855680)1, 7, 9 Babu E.... Endou H. (2002)
    5. Human renal organic anion transporter 4 operates as an asymmetric urate transporter. (PubMed id 17229912)1, 3 Hagos Y....Bahn A. (2007)
    6. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)1, 2 Taylor T.D....Sakaki Y. (2006)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. Mutational analysis of histidine residues in human organic anion transporter 4 (hOAT4). (PubMed id 15291761)1, 2 Zhou F.... You G. (2004)
    9. The role of glycine residues in the function of human organic anion transporter 4. (PubMed id 15102942)1, 2 Zhou F.... You G. (2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)

    External Searches for SLC22A11 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing SLC22A11 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55867 HGNC: 18120 AceView: SLC22A11 Ensembl:ENSG00000168065 euGenes: HUgn55867
    ECgene: SLC22A11 H-InvDB: SLC22A11

    Other Databases showing SLC22A11 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SLC22A11 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC22A11 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC22A11 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC22A11 gene:
    Search GeneIP for patents involving SLC22A11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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