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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC1A7 Gene

protein-coding   GIFtS: 60
GCID: GC01M053552

solute carrier family 1 (glutamate transporter), member...

 Explore 11 diseases affiliated with
SLC1A7 via our new
 Human Malady Compendium 
Biological research products
for SLC1A7
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Solute Carrier Family 1 (Glutamate Transporter), Member 71 2     AAAT2
EAAT51 2 3     Excitatory Amino Acid Transporter 52
Retinal Glutamate Transporter2 3     Excitatory Amino Acid Transporter 5 (Retinal Glutamate Transporter)2
Solute Carrier Family 1 Member 72 3     Excitatory Amino Acid Transporter 5a Long2

External Ids:    HGNC: 109451   Entrez Gene: 65122   Ensembl: ENSG000001623837   OMIM: 6044715   UniProtKB: O003413   

Export aliases for SLC1A7 gene to outside databases

Previous GC identifers: GC01M053188 GC01M052441 GC01M052911 GC01M052922 GC01M053264 GC01M053325 GC01M051668


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: EAA5_HUMAN, O00341
Function: Transports L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its
associated chloride conductance may participate in visual processing

summary for SLC1A7:
Glutamate transporters, also known as excitatory amino acid transporters (EAATs), are sodium- and
potassium-dependent members of the solute carrier family 6 (SLC1) found widely distributed throughout the
brain. There are five EAAT subtypes, each with a specific primary distribution; EAAT1 (cerebellar glia),
EAAT2 (forebrain glia), EAAT3 (cortical neurons), EAAT4 (cerebellar Purkinje neurons) and EAAT5 (retina).
Functions of glutamate transporters include regulation of excitatory neurotransmission, maintenance of low
ambient extracellular glutamate concentrations (protects against neurotoxicity) and providing glutamate for
metabolism through the glutamate-glutamine cycle. Overactivity of glutamate transporters has been implicated
in the pathophysiology of schizophrenia and other mental illnesses, whilst underactivity is seen in ischemia
and traumatic brain injury.

Gene Wiki entry for SLC1A7 (Excitatory amino-acid transporter 5)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC1A7 gene promoter:
         SRF   AML1a   SRF (504 AA)   Olf-1   STAT5A   Nkx2-5   POU2F1   POU2F1a   Chx10   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC1A7 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC1A7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC1A7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p32.3   Ensembl cytogenetic band:  1p32.3   HGNC cytogenetic band: 1p32.3

SLC1A7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC1A7 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M053552:  view genomic region     (about GC identifiers)

Start:
53,552,855 bp from pter      End:
53,608,289 bp from pter
Size:
55,435 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: EAA5_HUMAN, O00341 (See protein sequence)
Recommended Name: Excitatory amino acid transporter 5  
Size: 560 amino acids; 60658 Da
Subunit: Interacts with the PDZ domains of DLG4
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: Q5VVZ0 Q969Z8

Explore the universe of human proteins at neXtProt for SLC1A7: NX_O00341

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O00341

  • SLC1A7 Protein expression data from MOPED and PaxDb:    About this image 
    SLC1A7 Protein Expression
    REFSEQ proteins: NP_006662.3  
    ENSEMBL proteins: 
     ENSP00000360549   ENSP00000360546  
    Reactome Protein details: O00341
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    Uscn Proteins for SLC1A7

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016020membrane ----
    GO:0016021integral to membrane NAS--

    SLC1A7 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    SLC1A7 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR001991 Na-dicarboxylate_symporter
     IPR018107 Na-dicarboxylate_symporter_CS

    Graphical View of Domain Structure for InterPro Entry O00341

    ProtoNet protein and cluster: O00341

    1 Blocks protein family: IPB001991 Sodium:dicarboxylate symporter

    UniProtKB/Swiss-Prot: EAA5_HUMAN, O00341
    Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A7 subfamily


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: EAA5_HUMAN, O00341
    Function: Transports L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its
    associated chloride conductance may participate in visual processing

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005313L-glutamate transmembrane transporter activity TAS9108121
    GO:0017153sodium:dicarboxylate symporter activity IEA--
         
    SLC1A7 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SLC1A7:
     Increased S DNA content 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Slc1a7):
     behavior/neurological  homeostasis/metabolism 

    SLC1A7 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SLC1A7 

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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Amino acid and oligopeptide SLC transporters
    Amino acid and oligopeptide SLC transporters1.00
    Transport of inorganic cations/anions and amino acids/oligopeptides0.52
    2SLC-mediated transmembrane transport
    SLC-mediated transmembrane transport1.00
    Transmembrane transport of small molecules0.50
    3Transmission across Chemical Synapses
    Transmission across Chemical Synapses1.00
    Neuronal System0.67
    4GABA synthesis, release, reuptake and degradation
    Neurotransmitter Release Cycle0.53
    5Serotonin Neurotransmitter Release Cycle
    Glutamate Neurotransmitter Release Cycle0.42

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/8        Reactome Pathways for SLC1A7 (see all 8)
        Glutamate Neurotransmitter Release Cycle
    SLC-mediated transmembrane transport
    Transmembrane transport of small molecules
    Transmission across Chemical Synapses
    Amino acid and oligopeptide SLC transporters


    1         Kegg Pathway  (Kegg details for SLC1A7):
        Glutamatergic synapse


    SLC1A7 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC1A7

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for SLC1A7 (O003413 ENSP000003605494) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SNTA1Q134243I2D: score=1 
    ZNF420ENSP000003387704STRING: ENSP00000338770
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport TAS--
    GO:0006835dicarboxylic acid transport TAS9108121
    GO:0015813L-glutamate transport TAS9108121
    GO:0055085transmembrane transport TAS--

    SLC1A7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC1A7 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for SLC1A7 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    L-trans-2,4-PDC Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor[64769-66-0]
    DL-TBOASelective non-transportable inhibitor of EAATs--
    L-CCG-lll Potent, competitive glutamate uptake inhibitor [117857-95-1]
    7-Chlorokynurenic acidPotent competitive inhibitor of L-glutamate uptake[18000-24-3]
    L-(-)-threo-3-Hydroxyaspartic acidTransportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor[7298-99-9]

    2 HMDB Compounds for SLC1A7    About this table
    CompoundSynonyms CAS #PubMed Ids
    ChlorineCl2 (see all 13)16887-00-6--
    SodiumSodium (see all 2)7440-23-5--

    1 DrugBank Compound for SLC1A7    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    L-Glutamic Acid(2S)-2-Aminopentanedioic acid (see all 15)56-86-0target--15128272 9108121 17139284 17016423

    3 Novoseek chemical compound relationships for SLC1A7 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glutamate 63.1 25 15468177 (4), 9108121 (3), 11006260 (2), 7702599 (1) (see all 11)
    chloride 39.2 4 9108121 (2)
    nmda 21.1 2 9108121 (1)

    Search CenterWatch for drugs/clinical trials and news about SLC1A7 / EAA5 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC1A7 gene: 
    NM_006671.4  

    Unigene Cluster for SLC1A7:

    Solute carrier family 1 (glutamate transporter), member 7
    Hs.104637  [show with all ESTs]
    Unigene Representative Sequence: AB593059
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371494(uc021onm.1 uc001cuy.3 uc021onn.1 uc021ono.1)
    ENST00000488036(uc001cux.3) ENST00000371491(uc001cuz.4)

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    Additional cDNA sequence: 

    AB593059.1 AB593060.1 AB593061.1 AK093921.1 AK094048.1 BC000651.2 BC012119.1 BC017242.2 
    JF917096.1 JX162773.1 U76362.1 

    7 DOTS entries:

    DT.40120632  DT.100020708  DT.92045377  DT.99930322  DT.95249742  DT.100662009  DT.92378851 

    24/47 AceView cDNA sequences (see all 47):

    BI905991 BM461613 BU727462 BM680033 BU736781 CD672672 AX748366 BG329647 
    AL713112 AK093921 BG395207 BG472897 BQ437275 BM682194 BC012119 BX109737 
    BE259357 NM_006671 BQ638130 BU187310 BC000651 BQ434854 CF131219 BM704722 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SLC1A7    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13a · 13b
    SP1:                          -                             -           -                                       
    SP2:                                                                                                            
    SP3:                                                                    -                                       
    SP4:                                                                                                            
    SP5:                                                                                                            


    ECgene alternative splicing isoforms for SLC1A7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC1A7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAATAGGTAG
    SLC1A7 Expression
    About this image
    See SLC1A7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC1A7

    SOURCE GeneReport for Unigene cluster: Hs.104637

    UniProtKB/Swiss-Prot: EAA5_HUMAN, O00341
    Tissue specificity: Expressed primarily in retina. Detectable in liver, heart, muscle and brain

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for SLC1A7 gene from 6/23 species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves SLC1A71 solute carrier family 1 (glutamate transporter), member more 74.19(n)
    84.66(a)
      429106  XM_426662.2  XP_426662.2 
    lizard
    (Anolis carolinensis)
    Reptilia SLC1A76
    --
    83(a)
    1 ↔ 1
    4(114942933-115019933)
    zebrafish
    (Danio rerio)
    Actinopterygii slc1a7a1 solute carrier family 1 (glutamate transporter), member more 72.11(n)
    75.32(a)
      100170783  NM_001130622.1  NP_001124094.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Eaat13 sodium/excitatory glutamate cotransporter 44(a)     --
    worm
    (Caenorhabditis elegans)
    Secernentea glt-23 excitatory amino acid transporter 53(a)
    (best of 6)
      X(3531387-3534184)   --
    E. coli
    (Escherichia coli)
    Gamma proteobacteria gltP6
    dctA6
    (see all 3)
    glutamate/aspartate:proton symporter
    C4-dicarboxylic acid, orotate and citrate transpor...
    (see all 3)
    25(a)
    23(a)
    (see all 3)
    possible ortholog
    possible ortholog
    (see all 3)
    Chromosome(4292504-4293817)
    Chromosome(3680184-3681470)


    ENSEMBL Gene Tree for SLC1A7 (if available)
    TreeFam Gene Tree for SLC1A7 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC1A7 gene
    SLC1A32  SLC1A52  SLC1A12  SLC1A22  SLC1A42  SLC1A62  
    6 SIMAP similar genes for SLC1A7 using alignment to 6 protein entries:     EAA5_HUMAN (see all proteins):
    SLC1A3    SLC1A6    SLC1A2    SLC1A1    SLC1A5    SLC1A4

    SLC1A7 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1439 NCBI SNPs in SLC1A7 are shown (see all 1439    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs774629271,2
    F--53552366(+) GGGCAC/TGCCCC 1 -- ds50011Minor allele frequency- T:0.07WA 118
    rs1876317741,2
    --53552476(+) TAGACC/TATGGC 1 -- ds50010--------
    rs1909192011,2
    --53552712(+) GCCTGA/TTAGAT 1 -- ds50010--------
    rs1813682271,2
    --53552879(+) ATTTAA/GTTAAC 1 -- ut310--------
    rs1859450711,2
    --53552945(+) GGCCTG/TTGGGG 1 -- ut310--------
    rs775204521,2
    C,F--53552985(+) TCCACC/TAGAGC 1 -- ut313Minor allele frequency- T:0.05CSA WA 122
    rs10477411,2
    C,F,H--53553069(-) AAAGGC/TCCCCT 1 -- ut31 ese318Minor allele frequency- T:0.23MN NS EA WA NA 2402
    rs1899689031,2
    --53553447(+) TGTCAC/TAGCGG 1 -- ut310--------
    rs412985191,2
    --53553450(+) CACAGC/TGGGGC 1 -- ut310--------
    rs66587251,2
    H--53553453(+) AGCGGG/AGCCTC 1 -- ut314Minor allele frequency- A:0.00NS EA 420

    HapMap Linkage Disequilibrium report for SLC1A7 (53552855 - 53608289 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 10 variations for SLC1A7
         5 CNVs: 74484 48334 63739 84245 68646
         5 Indels: 39602 74483 44587 39601 84244

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SLC1A7 for disorders           About GeneDecksing

    OMIM gene information: 604471    OMIM disorders: --

    11 diseases for SLC1A7:    About MalaCards
    traumatic brain injury    brain injury    ischemia    schizophrenia
    retinitis    systemic lupus erythematosus    neuronitis    lupus erythematosus
    retinoblastoma    tuberculosis    mycobacterium tuberculosis

    Human Genome Epidemiology (HuGE) Navigator: SLC1A7 (5 documents)

    Export disorders for SLC1A7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC1A7 gene, integrated from 9 sources (see all 31):
    (articles sorted by number of sources associating them with SLC1A7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance. (PubMed id 9108121)1, 2, 3, 7, 9 Arriza J.L.... Amara S.G. (1997)
    2. Multiple loci influencing hippocampal degeneration ide ntified by genome scan. (PubMed id 22745009)1 Melville S.A....Farrer L.A. (2012)
    3. Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PubMed id 21697133)1 Oshikawa M.... Kato S. (2011)
    4. Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. (PubMed id 21408207)1 Chung S.A....Criswell L.A. (2011)
    5. L-type voltage-dependent calcium channel alpha subuni t 1C is a novel candidate gene associated with secondary hyperparathyroidism: a n application of haplotype-based analysis for multiple linked single nucleotide polymorphisms. (PubMed id 20424473)1 Yokoyama K....Hosoya T. (2010)
    6. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
    7. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    8. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)1 GratacA^s M....Carracedo A. (2008)
    9. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    10. Drugs, their targets and the nature and number of dru g targets. (PubMed id 17016423)7 Imming P....Meyer A. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6512 HGNC: 10945 AceView: SLC1A7 Ensembl:ENSG00000162383 euGenes: HUgn6512
    ECgene: SLC1A7 Kegg: 6512 H-InvDB: SLC1A7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC1A7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC1A7 gene:
    Search GeneIP for patents involving SLC1A7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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