Aliases for SLC1A6 Gene
External Ids for SLC1A6 Gene
Previous GeneCards Identifiers for SLC1A6 Gene
GeneCards Summary for SLC1A6 Gene
SLC1A6 (Solute Carrier Family 1 Member 6) is a Protein Coding gene. Diseases associated with SLC1A6 include Dicarboxylic Aminoaciduria. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Neurotransmitter Release Cycle. GO annotations related to this gene include L-glutamate transmembrane transporter activity and L-aspartate transmembrane transporter activity. An important paralog of this gene is SLC1A3.
UniProtKB/Swiss-Prot for SLC1A6 Gene
Transports L-glutamate and also L- and D-aspartate. Seems to act as a symport by cotransporting sodium.
Glutamate transporters, also known as excitatory amino acid transporters (EAATs), are sodium- and potassium-dependent members of the solute carrier family 6 (SLC1), widely distributed throughout the brain. There are five EAAT subtypes, each with a specific distribution.