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Aliases for SLC18B1 Gene

Aliases for SLC18B1 Gene

  • Solute Carrier Family 18, Subfamily B, Member 1 2 3
  • C6orf192 3 4 6
  • Solute Carrier Family 18 Member B1 3 4
  • Chromosome 6 Open Reading Frame 192 2
  • MFS-Type Transporter C6orf192 3
  • MFS-Type Transporter SLC18B1 3
  • DJ55C23.6 3

External Ids for SLC18B1 Gene

Previous Symbols for SLC18B1 Gene

  • C6orf192

Summaries for SLC18B1 Gene

Entrez Gene Summary for SLC18B1 Gene

  • This gene encodes a protein, which has high sequence similarity to rat, xenopus and zebrafish proteins. The protein function is unknown. [provided by RefSeq, Jul 2008]

GeneCards Summary for SLC18B1 Gene

SLC18B1 (Solute Carrier Family 18, Subfamily B, Member 1) is a Protein Coding gene. An important paralog of this gene is SLC18A2.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC18B1 Gene

Genomics for SLC18B1 Gene

Genomic Location for SLC18B1 Gene

Start:
132,769,368 bp from pter
End:
132,798,627 bp from pter
Size:
29,260 bases
Orientation:
Minus strand

Genomic View for SLC18B1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC18B1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC18B1 Gene

No data available for Regulatory Elements for SLC18B1 Gene

Proteins for SLC18B1 Gene

  • Protein details for SLC18B1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6NT16-S18B1_HUMAN
    Recommended name:
    MFS-type transporter SLC18B1
    Protein Accession:
    Q6NT16
    Secondary Accessions:
    • A8K1K3
    • B3KW77
    • Q6ISF2

    Protein attributes for SLC18B1 Gene

    Size:
    456 amino acids
    Molecular mass:
    48869 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLC18B1 Gene

Proteomics data for SLC18B1 Gene at MOPED

Post-translational modifications for SLC18B1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC18B1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC18B1 Gene

Domains for SLC18B1 Gene

Gene Families for SLC18B1 Gene

HGNC:
  • SLC :Solute carriers

Protein Domains for SLC18B1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

S18B1_HUMAN
Family:
  • Belongs to the major facilitator superfamily.:
    • Q6NT16
genes like me logo Genes that share domains with SLC18B1: view

Function for SLC18B1 Gene

miRNA for SLC18B1 Gene

miRTarBase miRNAs that target SLC18B1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SLC18B1 Gene

Localization for SLC18B1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC18B1 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SLC18B1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC18B1: view

Pathways for SLC18B1 Gene

SuperPathways for SLC18B1 Gene

No Data Available

Interacting Proteins for SLC18B1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000275227%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: ENSP00000275227 for SLC18B1 Gene via STRING

Gene Ontology (GO) - Biological Process for SLC18B1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC18B1: view

No data available for Pathways by source for SLC18B1 Gene

Transcripts for SLC18B1 Gene

Unigene Clusters for SLC18B1 Gene

Solute carrier family 18, subfamily B, member 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC18B1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15a · 15b · 15c
SP1: - - - - -
SP2: - - - -
SP3: - - - -
SP4: - - -
SP5: - -
SP6: -

Relevant External Links for SLC18B1 Gene

GeneLoc Exon Structure for
SLC18B1
ECgene alternative splicing isoforms for
SLC18B1

Expression for SLC18B1 Gene

mRNA expression in normal human tissues for SLC18B1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for SLC18B1 Gene

SOURCE GeneReport for Unigene cluster for SLC18B1 Gene Hs.347144

genes like me logo Genes that share expressions with SLC18B1: view

Orthologs for SLC18B1 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC18B1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC18B1 36
  • 99.63 (n)
  • 99.34 (a)
SLC18B1 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SLC18B1 36
  • 85.71 (n)
  • 83.3 (a)
SLC18B1 37
  • 82 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLC18B1 36
  • 86.29 (n)
  • 85.68 (a)
SLC18B1 37
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slc18b1 36
  • 81.01 (n)
  • 81.15 (a)
Slc18b1 16
Slc18b1 37
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SLC18B1 37
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 81 (a)
OneToMany
-- 37
  • 74 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Slc18b1 36
  • 81.01 (n)
  • 80.27 (a)
chicken
(Gallus gallus)
Aves C6ORF192 36
  • 68 (n)
  • 69.4 (a)
C6ORF192 37
  • 68 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SLC18B1 37
  • 70 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia slc18b1 36
  • 64.95 (n)
  • 63.23 (a)
Str.18211 36
zebrafish
(Danio rerio)
Actinopterygii slc18b1 36
  • 60.55 (n)
  • 55.06 (a)
slc18b1 37
  • 52 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001980 36
  • 45.84 (n)
  • 37.78 (a)
fruit fly
(Drosophila melanogaster)
Insecta prt 37
  • 15 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea F55A4.8 36
  • 47.28 (n)
  • 37.96 (a)
F55A4.8 37
  • 25 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 32 (a)
OneToOne
Species with no ortholog for SLC18B1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC18B1 Gene

ENSEMBL:
Gene Tree for SLC18B1 (if available)
TreeFam:
Gene Tree for SLC18B1 (if available)

Paralogs for SLC18B1 Gene

Paralogs for SLC18B1 Gene

genes like me logo Genes that share paralogs with SLC18B1: view

Variants for SLC18B1 Gene

Sequence variations from dbSNP and Humsavar for SLC18B1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs13144 -- 132,769,632(+) GTTAC(A/C)AAAAT utr-variant-3-prime, nc-transcript-variant
rs761125 -- 132,786,850(+) TCACT(A/G)ATACC intron-variant
rs998630 -- 132,770,154(-) GCCAG(C/T)GTCTT utr-variant-3-prime, nc-transcript-variant
rs1046448 -- 132,770,238(+) CATTT(A/C)TCAAC utr-variant-3-prime, nc-transcript-variant
rs1063172 -- 132,770,016(+) CTTGT(A/T)TTGTT utr-variant-3-prime, nc-transcript-variant

Relevant External Links for SLC18B1 Gene

HapMap Linkage Disequilibrium report
SLC18B1

No data available for Structural Variations from Database of Genomic Variants (DGV) for SLC18B1 Gene

Disorders for SLC18B1 Gene

No disorders were found for SLC18B1 Gene.

No data available for UniProtKB/Swiss-Prot for SLC18B1 Gene

Publications for SLC18B1 Gene

  1. C6ORF192 forms a unique evolutionary branch among solute carriers (SLC16, SLC17, and SLC18) and is abundantly expressed in several brain regions. (PMID: 19697161) Jacobsson J.A. … Fredriksson R. (J. Mol. Neurosci. 2010) 2 3
  2. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  3. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. (PMID: 21987572) Lee K.A. … Doedens J.R. (J. Biol. Chem. 2011) 3
  4. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 4
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for SLC18B1 Gene

  • antibodies-online peptides for SLC18B1
  • antibodies-online antibodies for SLC18B1
  • antibodies-online kits for SLC18B1

Sources for SLC18B1 Gene

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