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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC17A3 Gene

protein-coding   GIFtS: 54
GCID: GC06M025833

solute carrier family 17 (sodium phosphate), member 3
 Explore 7 diseases affiliated with
SLC17A3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SLC17A3    

Aliases
for SLC17A3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Solute Carrier Family 17 (Sodium Phosphate), Member 31 2
NPT41 2 3 5
Sodium/Phosphate Cotransporter 42 3
Na(+)/PI Cotransporter 42 3
Sodium-Dependent Phosphate Transport Protein 42
Solute Carrier Family 17 Member 33

External Ids:    HGNC: 109311   Entrez Gene: 107862   Ensembl: ENSG000001245647   OMIM: 6110345   UniProtKB: O004763   

Export aliases for SLC17A3 gene to outside databases

Previous GC identifers: GC06M025902 GC06M025953 GC06M025788


Summaries
for SLC17A3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SLC17A3:
The protein encoded by this gene is a voltage-driven transporter that excretes intracellular urate and organic anions
from the blood into renal tubule cells. Two transcript variants encoding different isoforms have been found for this
gene. The longer isoform is a plasma membrane protein with transporter activity while the shorter isoform localizes to
the endoplasmic reticulum. (provided by RefSeq, Aug 2012)

UniProtKB/Swiss-Prot: NPT4_HUMAN, O00476
Function: Isoform 2: voltage-driven, multispecific, organic anion transporter able to transport para-aminohippurate
(PAH), estrone sulfate, estradiol-17-beta-glucuronide, bumetanide, and ochratoxin A. Isoform 2 functions as urate
efflux transporter on the apical side of renal proximal tubule and is likely to act as an exit path for organic
anionic drugs as well as urate in vivo. May be involved in actively transporting phosphate into cells via Na(+)
cotransport




Genomic Views
for SLC17A3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC17A3 gene promoter:
         Nkx3-1 v4   AML1a   Lmo2   Nkx3-1 v1   POU6F1 (c2)   HNF-1A   Nkx3-1 v2   HNF-1   Nkx3-1 v3   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC17A3 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC17A3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC17A3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p22.2   HGNC cytogenetic band: 6p22.2

SLC17A3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC17A3 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M025833:  view genomic region     (about GC identifiers)

Start:
 25,833,294 bp from pter      End:
 25,882,514 bp from pter
Size:
 49,221 bases      Orientation:
 minus strand

Proteins
for SLC17A3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NPT4_HUMAN, O00476 (See protein sequence)
Recommended Name: Sodium-dependent phosphate transport protein 4  
Size: 420 amino acids; 46106 Da
Subcellular location: Isoform 1: Endoplasmic reticulum membrane; Multi-pass membrane protein
Subcellular location: Isoform 2: Cell membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAB53423.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B7WNJ5 B7Z511 Q8WWC7 Q9H533
Alternative splicing: 2 isoforms:  O00476-1   O00476-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC17A3: NX_O00476

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O00476

    • SLC17A3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001091956.1  NP_006623.2  

    ENSEMBL proteins: 
     ENSP00000421855   ENSP00000424027   ENSP00000380250   ENSP00000355307   ENSP00000353873  
     ENSP00000424729   ENSP00000415622  
    Reactome Protein details: O00476
    Human Recombinant Protein Products: 
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    Uscn Proteins for SLC17A3

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005789endoplasmic reticulum membrane IDA15505377
    GO:0005887integral to plasma membrane IDA--
    GO:0016324apical plasma membrane IDA--
    GO:0031526brush border membrane ISS--


    SLC17A3 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for SLC17A3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC17A3 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR020846 MFS_dom
     IPR011701 MFS
     IPR017373 Na-dep_P-transpt_4_prd
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry O00476

    ProtoNet protein and cluster: O00476

    UniProtKB/Swiss-Prot: NPT4_HUMAN, O00476
    Similarity: Belongs to the major facilitator superfamily. Sodium/anion cotransporter family


    Function
    for SLC17A3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NPT4_HUMAN, O00476
    Function: Isoform 2: voltage-driven, multispecific, organic anion transporter able to transport para-aminohippurate
    (PAH), estrone sulfate, estradiol-17-beta-glucuronide, bumetanide, and ochratoxin A. Isoform 2 functions as urate
    efflux transporter on the apical side of renal proximal tubule and is likely to act as an exit path for organic
    anionic drugs as well as urate in vivo. May be involved in actively transporting phosphate into cells via Na(+)
    cotransport

         Genatlas biochemistry entry for SLC17A3:
    solute carrier family 17 (sodium/phosphate cotransport) member 3,expressed in liver and kidney

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    Gene Editing
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    Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005436sodium:phosphate symporter activity ISS--
    GO:0008308voltage-gated anion channel activity IDA--
    GO:0008514organic anion transmembrane transporter activity IDA--
    GO:0015143urate transmembrane transporter activity IDA--
    GO:0015238drug transmembrane transporter activity IDA--


    SLC17A3 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SLC17A3:
     Increased gamma-H2AX phosphory 


    Pathways & Interactions
    for SLC17A3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Ion channel transport
    		Ion channel transport1.00
    		Stimuli-sensing channels0.49
    2SLC-mediated transmembrane transport
    		Transmembrane transport of small molecules0.50

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3        Reactome Pathways for SLC17A3
        Transmembrane transport of small molecules
    Stimuli-sensing channels
    Ion channel transport



    SLC17A3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC17A3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for SLC17A3 (ENSP000003802504) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PDZK1ENSP000003421434STRING: ENSP00000342143
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006814sodium ion transport ISS--
    GO:0006817phosphate ion transport ISS--
    GO:0006855drug transmembrane transport IDA--
    GO:0015711organic anion transport IDA--
    GO:0015747urate transport IDA--


    SLC17A3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC17A3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC17A3

    1 HMDB Compound for SLC17A3    About this table
    CompoundSynonyms CAS #PubMed Ids
    SodiumSodium (see all 2)7440-23-5--
    Search CenterWatch for drugs/clinical trials and news about SLC17A3 / NPT4 

    Transcripts
    for SLC17A3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SLC17A3 gene (2 alternative transcripts): 
    NM_001098486.1  NM_006632.3  

    Unigene Cluster for SLC17A3:

    Solute carrier family 17 (sodium phosphate), member 3
    Hs.327179  [show with all ESTs]
    Unigene Representative Sequence: AK298271
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000481949 ENST00000505420 ENST00000397060(uc003nfk.4 uc003nfi.4)
    ENST00000361703 ENST00000360657 ENST00000509714(uc011djz.1) ENST00000506105
    ENST00000503922(uc011dka.1) ENST00000308453 ENST00000449356

    miRNA
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    hsa-miR-587
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    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    AK296082.1 AK298271.1 AK298367.1 BC017952.1 U90545.1 Z83953.1 

    5 DOTS entries:

    DT.403125  DT.100742561  DT.121332300  DT.40120631  DT.95204537 

    19 AceView cDNA sequences:

    AI222455 CB163247 AI733707 U90545 BG427288 AI244777 NM_006632 BX107915 
    BC017952 AI821963 BF431676 AA858296 Z83953 AI311320 AI792430 AA706766 
    AI247271 AA814153 BG399960 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SLC17A3 (see all 6)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14
    SP1:                    -                 -                                   -                                             
    SP2:        -     -     -                 -                                   -                                             
    SP3:                    -                 -     -                                                                           
    SP4:                    -                                                                                                   
    SP5:                                      -     -                                                                           


    ECgene alternative splicing isoforms for SLC17A3

    Expression
    for SLC17A3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC17A3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTGGGAGGCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SLC17A3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyEpithelial TubuleKidney
    KidneyGlomerulusKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Human kidney epithelial cell spheroids (Kidney spheroids for...)

    See SLC17A3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC17A3

    SOURCE GeneReport for Unigene cluster: Hs.327179

    UniProtKB/Swiss-Prot: NPT4_HUMAN, O00476
    Tissue specificity: Expressed in the liver and kidney. It is detected in proximal tubules in renal cortex as well as
    some tubules and glomeruli, with highest expression at the apical side of proximal tubules (at protein level)

        SABiosciences Expression via Pathway-Focused PCR Array including SLC17A3: 
              Hepatotoxicity in human mouse rat

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    In Situ
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    Orthologs
    for SLC17A3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC17A3 gene from 4/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    zebrafish
    (Danio rerio)    		 Actinopterygii CU929219.16
    		 --
    		 32(a)
    		 1 → many
    		 19(44811733-44829601)
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG124906
    CG78816
    (see all 24)    		 --
    		 28(a)
    27(a)
    (see all 24)    		 possible ortholog
    possible ortholog
    (see all 24)    		 2R(18722170-18724224)
    2R(1848503-1854341)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons PHT4;66
    		 putative anion transporter 5
    		 24(a)
    		 1 → many
    		 5(17874885-17877564)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    		 transporter, major facilitator family, putative, e...
    transporter, major facilitator family, putative, e...
    		 24(a)
    22(a)
    		 many ↔ many
    many ↔ many
    		 11(4409142-4411772)
    12(4043466-4046391)


    ENSEMBL Gene Tree for SLC17A3 (if available)
    TreeFam Gene Tree for SLC17A3 (if available) 

    Paralogs
    for SLC17A3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC17A3 gene
    SLC17A72  SLC17A82  SLC17A62  SLC17A12  SLC17A42  SLC17A52  SLC17A92  SLC17A22  
    5 SIMAP similar genes for SLC17A3 using alignment to 4 protein entries:     NPT4_HUMAN (see all proteins):
    SLC17A1    SLC17A4    SLC17A5    SLC17A2    SLC17A7

    SLC17A3 for paralogs           About GeneDecksing



    Genomic Variants
    for SLC17A3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    UniProtKB/Swiss-Prot: NPT4_HUMAN, O00476
    Polymorphism: Genetic variations in SLC17A3 influence the variance in serum uric acid concentrations and define the
    serum uric acid concentration quantitative trait locus 4 (UAQTL4) [MIM:612671]. Excess serum accumulation of uric acid
    can lead to the development of gout, a common disorder characterized by tissue deposition of monosodium urate crystals
    as a consequence of hyperuricemia


    10/502 NCBI SNPs in SLC17A3 are shown (see all 502)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs782591491,2
    		--25788068(+) AGAACC/TGAACA 2 -- ds50011Minor allele frequency- T:0.01EA 120
    rs560107471,2
    		C,--25788206(+) AAAGAC/GAGACT 2 -- ds50012Minor allele frequency- G:0.33WA CSA 3
    rs766302541,2
    		C,F,--25788227(+) AACACC/AGCCTG 2 -- ds50011Minor allele frequency- A:0.03EA 120
    rs287001691,2
    		C--25788277(+) GGACAA/GGGGAG 2 -- ds50011Minor allele frequency- G:0.00NA 2
    rs32157701,2
    		C,--25788670(-) TTTTTT/-CCTGT 2 -- ut31 trp31Minor allele frequency- -:0.50NA 2
    rs1903130541,2
    		C--25789111(+) GGCTTG/TATAGT 2 -- int10--------
    rs715573081,2
    		C,--25789610(+) ATTTTG/TTTTTT 2 -- int11Minor allele frequency- T:0.50NA 2
    rs760705041,2
    		--25789618(+) TTTTTA/TAATCA 2 -- int10--------
    rs1138706101,2
    		--25790539(+) TCCTCT/CCACCC 2 -- int11Minor allele frequency- C:0.00CSA 1
    rs11651931,2
    		F,H,--25790550(-) ttgagA/Tgtgaa 2 -- int15Minor allele frequency- T:0.02NS EA WA 538

    HapMap Linkage Disequilibrium report for SLC17A3 (25833294 - 25882514 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SLC17A3: --
    Human Gene Mutation Database (HGMD): SLC17A3

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for SLC17A3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC17A3 for disorders           About GeneDecksing

    OMIM gene information: 611034   
    OMIM disorders: 232240  
    7 diseases for SLC17A3:    About MalaCards
    glycogen storage disease ic    glycogen storage disease    intrahepatic cholangiocarcinoma    hemochromatosis
    cholangiocarcinoma    gout    schizophrenia

    1 disease from the University of Copenhagen DISEASES database for SLC17A3:
    Hyperuricemia
    Human Genome Epidemiology (HuGE) Navigator: SLC17A3 (7 documents)

    Export disorders for SLC17A3 gene to outside databases

    Publications
    for SLC17A3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC17A3 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with SLC17A3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A 1.1-Mb transcript map of the hereditary hemochromatosis locus. (PubMed id 9149941)1, 2, 3 Ruddy D.A.... Feder J.N. (1997)
    2. NPT4, a new microsomal phosphate transporter: mutation analysis in glycogen storage disease type Ic. (PubMed id 15505377)1, 2, 9 Melis D.... Verheijen F. (2004)
    3. Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate. (PubMed id 20810651)1, 2 Jutabha P....Sakurai H. (2010)
    4. A novel human organic anion transporter NPT4 mediates the transport of ochratoxin A. (PubMed id 21778665)1 Jutabha P....Sakurai H. (2011)
    5. Functional analysis of human sodium-phosphate transpo rter 4 (NPT4/SLC17A3) polymorphisms. (PubMed id 21282933)1 Jutabha P....Sakurai H. (2011)
    6. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    7. Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. (PubMed id 20587610)1 Ucisik-Akkaya E....Tevfik Dorak M. (2010)
    8. Common variants in SLC17A3 gene affect intra-personal variation in serum uric acid levels in longitudinal time series. (PubMed id 20162743)1 Polasek O....KolciA8 I. (2010)
    9. Common polymorphisms influencing serum uric acid leve ls contribute to susceptibility to gout, but not to coronary artery disease. (PubMed id 19890391)1 Stark K....Hengstenberg C. (2009)
    10. Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. (PubMed id 19862010)1 Ganesh S.K....Lin J.P. (2009)

    External Searches for SLC17A3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing SLC17A3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10786 HGNC: 10931 AceView: SLC17A3 Ensembl:ENSG00000124564 euGenes: HUgn10786
    ECgene: SLC17A3 H-InvDB: SLC17A3

    Other Databases showing SLC17A3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SLC17A3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC17A3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC17A3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC17A3 gene:
    Search GeneIP for patents involving SLC17A3

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