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SLC17A1 Gene

protein-coding   GIFtS: 62
GCID: GC06M025785

Solute Carrier Family 17 (Organic Anion Transporter), Member...

(Previous names: solute carrier family 17 (sodium phosphate), member 1)
(Previous symbol: NPT1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 17 (Organic Anion Transporter), Member 11 2     NAPI-12
NPT11 2 3 5     NPT-12
Solute Carrier Family 17 (Sodium Phosphate), Member 11 2     na/Pi-42
Renal Na(+)-Dependent Phosphate Cotransporter 12 3     Sodium Phosphate Transporter2
Renal Sodium-Dependent Phosphate Transport Protein 12 3     Sodium-Dependent Phosphate Transport Protein 12
Renal Sodium-Phosphate Transport Protein 12 3     Sodium/Phosphate Type I Cotransporter2
Sodium/Phosphate Cotransporter 12 3     Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 12
Solute Carrier Family 17 Member 12 3     Na/Pi-43
Na(+)/PI Cotransporter 12 3     

External Ids:    HGNC: 109291   Entrez Gene: 65682   Ensembl: ENSG000001245687   OMIM: 1823085   UniProtKB: Q149163   

Export aliases for SLC17A1 gene to outside databases

Previous GC identifers: GC06M025840 GC06M025891


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SLC17A1 Gene:
SLC17A1 (solute carrier family 17 (organic anion transporter), member 1) is a protein-coding gene. Diseases associated with SLC17A1 include cardiovascular disease risk factor, and fanconi syndrome. GO annotations related to this gene include sodium-dependent phosphate transmembrane transporter activity and symporter activity. An important paralog of this gene is SLC17A7.

UniProtKB/Swiss-Prot: NPT1_HUMAN, Q14916
Function: Important for the resorption of phosphate by the kidney. May be involved in actively transporting
phosphate into cells via Na(+) cotransport in the renal brush border membrane

Gene Wiki entry for SLC17A1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NT_007592.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC17A1 gene promoter:
         RFX1   GATA-3   CUTL1   GATA-1   GATA-2   C/EBPalpha   RORalpha1   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC17A1 promoter sequence
   Search Chromatin IP Primers for SLC17A1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC17A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p22.2   Ensembl cytogenetic band:  6p22.2   HGNC cytogenetic band: 6p22.2

SLC17A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC17A1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M025785:  view genomic region     (about GC identifiers)

Start:
25,783,125 bp from pter      End:
25,832,287 bp from pter
Size:
49,163 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NPT1_HUMAN, Q14916 (See protein sequence)
Recommended Name: Sodium-dependent phosphate transport protein 1  
Size: 467 amino acids; 51132 Da
Subunit: Interacts with PDZK1 (By similarity)
Caution: It is uncertain whether Met-1 or Met-3 is the initiator
Sequence caution: Sequence=BAA05888.1; Type=Erroneous initiation; Sequence=CAI19543.1; Type=Erroneous initiation;
Secondary accessions: A8K418 O60761 Q13783 Q3MIP5 Q5MJP8 Q5TB83 Q96KL8
Alternative splicing: 2 isoforms:  Q14916-1   Q14916-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC17A1: NX_Q14916

Explore proteomics data for SLC17A1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn41, Asn49, Asn58
  • Modification sites at PhosphoSitePlus

  • See SLC17A1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005065.2  
    ENSEMBL proteins: 
     ENSP00000244527   ENSP00000367118   ENSP00000420614   ENSP00000420546   ENSP00000410549  
    Reactome Protein details: Q14916

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Sodium/phosphate cotransporter 1
    Type I sodium-phosphate co-transporters

    4 InterPro protein domains:
     IPR011701 MFS
     IPR020846 MFS_dom
     IPR016196 MFS_dom_general_subst_transpt
     IPR004745 Pi_cotranspt

    Graphical View of Domain Structure for InterPro Entry Q14916

    ProtoNet protein and cluster: Q14916

    UniProtKB/Swiss-Prot: NPT1_HUMAN, Q14916
    Similarity: Belongs to the major facilitator superfamily. Sodium/anion cotransporter family


    SLC17A1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NPT1_HUMAN, Q14916
    Function: Important for the resorption of phosphate by the kidney. May be involved in actively transporting
    phosphate into cells via Na(+) cotransport in the renal brush border membrane

         Genatlas biochemistry entry for SLC17A1:
    solute carrier family 17 (sodium/phosphate cotransport),member 1,expressed in kidney

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015114phosphate ion transmembrane transporter activity ----
    GO:0015293symporter activity IEA--
    GO:0015321sodium-dependent phosphate transmembrane transporter activity TAS8867793
         
    SLC17A1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SLC17A1:
     Decreased number of cells in m 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC17A1
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    miRNA
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    miRTarBase miRNAs that target SLC17A1:
    hsa-mir-335-5p (MIRT019052)

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    2 qRT-PCR Assays for microRNAs that regulate SLC17A1:
    hsa-miR-3173-3p hsa-miR-340
    SwitchGear 3'UTR luciferase reporter plasmidSLC17A1 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NPT1_HUMAN, Q14916: Membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane4
    endoplasmic reticulum1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral component of plasma membrane TAS8288239
    GO:0016020membrane TAS8288239
    GO:0016021integral component of membrane ----

    SLC17A1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SLC17A1 About    
    See pathways by source

    SuperPathContained pathways About
    1Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    SLC-mediated transmembrane transport0.47
    Transport of inorganic cations/anions and amino acids/oligopeptides0.38
    Transmembrane transport of small molecules0.47
    Organic anion transporters0.00

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for SLC17A1
        Organic anion transporters



    SLC17A1 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC17A1
    Interactions:

        Search GeneGlobe Interaction Network for SLC17A1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for SLC17A1 (Q149163 ENSP000002445274) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PDZD3Q86UT53, ENSP000003271074I2D: score=2 STRING: ENSP00000327107
    SLC9A3R1O147453, ENSP000002626134I2D: score=2 STRING: ENSP00000262613
    PDZK1Q5T2W13, ENSP000003421434I2D: score=4 STRING: ENSP00000342143
    MAST2Q6P0Q83, ENSP000003546714I2D: score=1 STRING: ENSP00000354671
    HSP90AA1P079003I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport TAS--
    GO:0006814sodium ion transport IEA--
    GO:0006817phosphate ion transport TAS8867793
    GO:0035435phosphate ion transmembrane transport ----
    GO:0044341sodium-dependent phosphate transport TAS8867793

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    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
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    Browse Tocris compounds for SLC17A1 (NPT1)

    2 HMDB Compounds for SLC17A1    About this table
    CompoundSynonyms CAS #PubMed Ids
    PhosphateNFB Orthophosphate (see all 13)14265-44-2--
    SodiumSodium (see all 2)7440-23-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SLC17A1 gene: 
    NM_005074.3  

    Unigene Cluster for SLC17A1:

    Solute carrier family 17 (sodium phosphate), member 1
    Hs.205816  [show with all ESTs]
    Unigene Representative Sequence: NM_005074
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000244527(uc011djy.2 uc003nfh.4) ENST00000377886 ENST00000476801(uc010jqb.1)
    ENST00000468082 ENST00000427328(uc010jqc.1)
    miRNA
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    hsa-miR-3173-3p hsa-miR-340
    SwitchGear 3'UTR luciferase reporter plasmidSLC17A1 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat SLC17A1

    Additional mRNA sequence: 

    AK290783.1 AK308035.1 AY780791.1 BC101745.1 BC101747.1 BC143579.1 D28532.1 X71355.1 
    Y10513.1 Z83952.1 

    2 DOTS entries:

    DT.112266  DT.65287253 

    Selected AceView cDNA sequences (see all 42):

    AW779672 BX106560 AA004989 NM_170745 AW000949 AI768648 NM_005074 X71355 
    N53056 CB163564 Y10513 AW195710 AI640281 AI433406 N73241 CB163294 
    AL700122 AI262144 AI522108 BU567795 BG054690 BX506428 BX106481 BC062211 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SLC17A1    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13
    SP1:                                                                                          
    SP2:                                                        -                                 
    SP3:                                                                                          


    ECgene alternative splicing isoforms for SLC17A1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC17A1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SLC17A1 Expression
    About this image


    SLC17A1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Neurons
             Type1 Off Cone Bipolar Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             Type1 Off Cone Bipolar Cells Inner Nuclear Layer
     
     Liver (Hepatobiliary System)
     
     Kidney (Urinary System)
    SLC17A1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC17A1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.205816

    UniProtKB/Swiss-Prot: NPT1_HUMAN, Q14916
    Tissue specificity: Expressed in kidney cortex, liver and brain but not in other tissues

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SLC17A1 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc17a11 , 5 solute carrier family 17 (sodium phosphate), member more1, 5 74.98(n)1
    65.59(a)1
      13 (9.97 cM)5
    205041  NM_001170638.11  NP_001164109.11 
     238677505 
    zebrafish
    (Danio rerio)
    Actinopterygii CU929219.16
    Uncharacterized protein
    33(a)
    1 → many
    19(44811733-44829601) ENSDARG00000086739


    ENSEMBL Gene Tree for SLC17A1 (if available)
    TreeFam Gene Tree for SLC17A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC17A1 gene
    SLC17A72  SLC17A82  SLC17A62  SLC17A32  SLC17A42  SLC17A52  SLC17A92  SLC17A22  
    7 SIMAP similar genes for SLC17A1 using alignment to 6 protein entries:     NPT1_HUMAN (see all proteins):
    SLC17A3    SLC17A4    SLC17A2    SLC17A5    SLC17A7    SLC17A6
    SLC17A8

    SLC17A1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC17A1 (see all 1073)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1897749821,2
    --25782626(+) TGTAGC/TATCTT 1 -- int10--------
    rs1150500391,2
    C,F--25782665(+) AGTAAG/TTGCCA 1 -- int11Minor allele frequency- T:0.01NA 120
    rs1456515281,2
    --25782759(+) GAAGGA/TAAAGG 1 -- int10--------
    rs800983431,2
    C,F--25782871(+) TGCTCC/TGTATC 1 -- int11Minor allele frequency- T:0.02NA 120
    rs1813746221,2
    C--25782928(+) TGTTCC/TTTCTT 1 -- int10--------
    rs1381849801,2
    C--25782954(+) TTAGTC/TATTTC 1 -- int10--------
    rs1861816901,2
    --25782996(+) CCAGCA/GAGGGA 1 -- int10--------
    rs1902927591,2
    --25783005(+) GAGCTA/GACTTG 1 -- int10--------
    rs94675961,2
    C,F,A,H--25783022(+) TTCCTC/TTAAAA 1 -- int126Minor allele frequency- T:0.46NA NS EA CSA WA 2489
    rs1814327221,2
    C--25783121(+) GAAAAA/TGTCTT 1 -- int10--------

    HapMap Linkage Disequilibrium report for SLC17A1 (25783125 - 25832287 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SLC17A1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv883489CNV Gain21882294

    Human Gene Mutation Database (HGMD): SLC17A1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC17A1
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC17A1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 182308    OMIM disorders: --

    8 diseases for SLC17A1:    
    About MalaCards
    cardiovascular disease risk factor    fanconi syndrome    gout    hyperuricemia
    osteomalacia    coronary artery disease    schizophrenia    alzheimer's disease

    2 diseases from the University of Copenhagen DISEASES database for SLC17A1:
    Gout     Hyperuricemia

    SLC17A1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC17A1
    Human Genome Epidemiology (HuGE) Navigator: SLC17A1 (8 documents)

    Export disorders for SLC17A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC17A1 gene, integrated from 10 sources (see all 41):
    (articles sorted by number of sources associating them with SLC17A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning of the cDNA encoding a human renal sodium phosphate transport protein and its assignment to chromosome 6p21.3-p23. (PubMed id 8288239)1, 2, 3, 9 Chong S.S.... Hughes M.R. (Genomics 1993)
    2. Cloning and functional expression of a Na(+)-dependent phosphate co- transporter from human kidney: cDNA cloning and functional expression. (PubMed id 7826357)1, 2, 9 Miyamoto K.... Takeda E. (Biochem. J. 1995)
    3. Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels. (PubMed id 21149283)1, 4 Oexle K....Meitinger T. (Hum. Mol. Genet. 2011)
    4. Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels. (PubMed id 21208937)1, 4 Pichler I....Pramstaller P.P. (Hum. Mol. Genet. 2011)
    5. Sodium-dependent phosphate cotransporter type 1 sequence polymorphisms in male patients with gout. (PubMed id 19556210)1, 4 Urano W....Yamanaka H. (Ann. Rheum. Dis. 2010)
    6. A genome-wide association study of red blood cell traits using the electronic medical record. (PubMed id 20927387)1, 4 Kullo I.J....Chute C.G. (PLoS ONE 2010)
    7. Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. (PubMed id 20884846)1, 4 Yang Q....Coresh J. (Circ Cardiovasc Genet 2010)
    8. Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels. (PubMed id 19084217)1, 4 Benyamin B....Visscher P.M. (Am. J. Hum. Genet. 2009)
    9. Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. (PubMed id 19204726)1, 4 Chapuis J....Lambert J.C. (Mol. Psychiatry 2009)
    10. Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. (PubMed id 19503597)1, 4 Kolz M....Gieger C. (PLoS Genet. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6568 HGNC: 10929 AceView: SLC17A1andHIST1H2AA Ensembl:ENSG00000124568 euGenes: HUgn6568
    ECgene: SLC17A1 H-InvDB: SLC17A1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SLC17A1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC17A1 gene:
    Search GeneIP for patents involving SLC17A1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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