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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC16A8 Gene

protein-coding   GIFtS: 57
GCID: GC22M038474

Solute Carrier Family 16 (Monocarboxylate Transporter),...

(Previous names: solute carrier 16 (monocarboxylic acid transporters), member...)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 16 (Monocarboxylate Transporter), Member 81 2     MCT32 3
Solute Carrier 16 (Monocarboxylic Acid Transporters), Member 81 2     MCT 32 3
Monocarboxylate Transporter 31 2     REMP2
Solute Carrier Family 16 Member 82 3     Solute Carrier Family 16, Member 8 (Monocarboxylic Acid Transporter 3)2

External Ids:    HGNC: 162701   Entrez Gene: 235392   Ensembl: ENSG000001001567   OMIM: 6104095   UniProtKB: O959073   

Export aliases for SLC16A8 gene to outside databases

Previous GC identifers: GC22M035088 GC22M036717 GC22M036798 GC22M021438


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SLC16A8 Gene:
SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport
across cell membranes (Yoon et al., 1999 (PubMed 10493836)).(supplied by OMIM, Apr 2010)

GeneCards Summary for SLC16A8 Gene: 
SLC16A8 (solute carrier family 16 (monocarboxylate transporter), member 8) is a protein-coding gene. Diseases associated with SLC16A8 include hyperparathyroidism, and retinitis, and among its related super-pathways are Transmembrane transport of small molecules and Pyruvate metabolism. GO annotations related to this gene include symporter activity and lactate transmembrane transporter activity. An important paralog of this gene is SLC16A4.

UniProtKB/Swiss-Prot: MOT3_HUMAN, O95907
Function: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of
many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and
isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NC_018933.2  NT_011520.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC16A8 gene promoter:
         AhR   NF-1/L   NF-1   Sp1   FOXL1   Arnt   c-Ets-1   CREB   Zic3   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC16A8 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC16A8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC16A8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q12.3-q13.2   Ensembl cytogenetic band:  22q13.1   HGNC cytogenetic band: 22q12.3-q13.2

SLC16A8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC16A8 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M038474:  view genomic region     (about GC identifiers)

Start:
38,474,141 bp from pter      End:
38,480,100 bp from pter
Size:
5,960 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MOT3_HUMAN, O95907 (See protein sequence)
Recommended Name: Monocarboxylate transporter 3  
Size: 504 amino acids; 52319 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: Q9UBE2

Explore the universe of human proteins at neXtProt for SLC16A8: NX_O95907

Explore proteomics data for SLC16A8 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O95907

  • SLC16A8 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC16A8 Protein Expression
    REFSEQ proteins: NP_037488.2  
    ENSEMBL proteins: 
     ENSP00000321735   ENSP00000409547  
    Reactome Protein details: O95907
    Human Recombinant Protein Products for SLC16A8: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SLC16A8 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane TAS10493836
    GO:0016020membrane TAS10493836
    GO:0016021integral to membrane ----

    SLC16A8 for ontologies           About GeneDecksing



    SLC16A8 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for SLC16A8 

    Assay Products for SLC16A8: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Monocarboxylate transporter 3 
    SLC16 family of monocarboxylate transporters

    4 InterPro protein domains:
     IPR020846 MFS_dom
     IPR004743 Monocarb_transpt
     IPR011701 MFS
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry O95907

    ProtoNet protein and cluster: O95907

    UniProtKB/Swiss-Prot: MOT3_HUMAN, O95907
    Similarity: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family


    SLC16A8 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MOT3_HUMAN, O95907
    Function: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of
    many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and
    isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015129lactate transmembrane transporter activity TAS10493836
    GO:0015293symporter activity IEA--
    GO:0015355secondary active monocarboxylate transmembrane transporter activity IEA--
         
    SLC16A8 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for SLC16A8:
     Cell cycle / mitosis defect  Increased gamma-H2AX phosphory 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Slc16a8):
     vision/eye 

    SLC16A8 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Slc16a8tm1Njp for SLC16A8

       inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC16A8 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC16A8 
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SLC16A8 About   (see all 8)                                                                                              See pathways by source

    SuperPathContained pathways About
    1SLC-mediated transmembrane transport
    SLC-mediated transmembrane transport0.50
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    Transmembrane transport of small molecules0.50
    2Pyruvate metabolism
    Pyruvate metabolism0.60
    Pyruvate metabolism and Citric Acid (TCA) cycle0.49
    3Bile salt and organic anion SLC transporters
    Bile salt and organic anion SLC transporters0.42
    Proton-coupled monocarboxylate transport0.33
    4Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    The citric acid (TCA) cycle and respiratory electron transport0.72
    5Platelet activation, signaling and aggregation
    Hemostasis0.43

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/12        Reactome Pathways for SLC16A8 (see all 12)
        Hemostasis
    Pyruvate metabolism
    Bile salt and organic anion SLC transporters
    Metabolism
    The citric acid (TCA) cycle and respiratory electron transport



    SLC16A8 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC16A8

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for SLC16A8 (O959072, 3 ENSP000003217354) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DNAJB9Q9UBS32, 3MINT-65683 I2D: score=5 
    RAB1AP628202, 3, ENSP000003872864MINT-63966 I2D: score=5 STRING: ENSP00000387286
    BSGENSP000003337694STRING: ENSP00000333769
    SLC16A1ENSP000003586404STRING: ENSP00000358640
    SLC16A3ENSP000003761504STRING: ENSP00000376150
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006090pyruvate metabolic process TAS--
    GO:0007596blood coagulation TAS--
    GO:0015711organic anion transport ----
    GO:0015727lactate transport TAS10493836
    GO:0035873lactate transmembrane transport TAS10493836

    SLC16A8 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC16A8 (MOT3)

    1 HMDB Compound for SLC16A8    About this table
    CompoundSynonyms CAS #PubMed Ids
    Pyruvic acid2-Oxopropanoate (see all 14)127-17-3--

    1 DrugBank Compound for SLC16A8    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Pyruvic acid2-Oxopropanoate (see all 8)127-17-3target--16514190

    Search CenterWatch for drugs/clinical trials and news about SLC16A8 / MOT3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC16A8 gene: 
    NM_013356.2  

    Unigene Cluster for SLC16A8:

    Solute carrier family 16, member 8 (monocarboxylic acid transporter 3)
    Hs.745256  [show with all ESTs]
    Unigene Representative Sequence: NM_013356
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000320521(uc003auu.3) ENST00000469516 ENST00000427592
    miRNA
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    Additional mRNA sequence: AF132610.1 

    2 DOTS entries:

    DT.40281026  DT.100735613 

    14 AceView cDNA sequences:

    BM714896 BF508676 BM709138 H55065 BM716163 BM716167 BM714916 AF132610 
    NM_013356 AI005004 BF476254 BM705316 AI476420 AW166384 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC16A8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTGTCGCCA
    SLC16A8 Expression
    About this image


    See SLC16A8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC16A8

    SOURCE GeneReport for Unigene cluster: Hs.745256

    UniProtKB/Swiss-Prot: MOT3_HUMAN, O95907
    Tissue specificity: Retinal pigment epithelium

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC16A8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC16A8 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc16a81 , 5 solute carrier family 16 (monocarboxylic acid transporters), more1, 5 84.45(n)1
    88.49(a)1
      15 (37.70 cM)5
    572741  NM_020516.21  NP_065262.11 
     792510145 
    chicken
    (Gallus gallus)
    Aves SLC16A81 solute carrier family 16, member 8 (monocarboxylic more 67.11(n)
    67.79(a)
      396041  NM_205140.1  NP_990471.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC16A86
    Uncharacterized protein
    56(a)
    1 ↔ 1
    GL343460.1(272057-279518)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5578841 monocarboxylate transporter 3-like 59.72(n)
    64.12(a)
      557884  XM_681038.1  XP_686130.1 
    K. lactis yeast
    (Kluyveromyces lactis)
    Saccharomycetes KLLA0F11077g1 hypothetical protein 36.7(n)
    29.67(a)
      2895123  XM_455584.1  XP_455584.1 


    ENSEMBL Gene Tree for SLC16A8 (if available)
    TreeFam Gene Tree for SLC16A8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC16A8 gene
    SLC16A42  SLC16A32  SLC16A102  SLC16A52  SLC16A112  SLC16A22  SLC16A62  SLC16A142  
    SLC16A72  SLC16A12  SLC16A122  SLC16A92  SLC16A132  
    10 SIMAP similar genes for SLC16A8 using alignment to 2 protein entries:     MOT3_HUMAN (see all proteins):
    SLC16A3    SLC16A7    SLC16A1    SLC16A5    SLC16A11    SLC16A12
    SLC16A10    SLC16A14    SLC16A6    SLC16A13

    SLC16A8 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/171 SNPs in SLC16A8 are shown (see all 171)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs20128591,2
    C,F,A,H--38473706(+) AGCAAG/AGAAGT 1 -- int125Minor allele frequency- A:0.34NS EA NA WA CSA 2531
    rs592414301,2
    C,F--38473716(+) TCAGCG/TGGGCT 1 -- int12Minor allele frequency- T:0.05WA 120
    rs1152237191,2
    F--38473733(+) CAAACC/TGACCC 1 -- int11Minor allele frequency- T:0.03WA 118
    rs20128671,2
    C,A--38473812(-) CAACTA/CGGGTT 1 -- int13Minor allele frequency- C:0.08WA NA EA 242
    rs734198981,2
    C--38473869(+) GGGGGC/ACTTCA 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1813157121,2
    --38473923(+) GTGCCC/TACCCA 1 -- int10--------
    rs1166598131,2
    F--38474034(+) GCCCAC/TCTAGA 1 -- int11Minor allele frequency- T:0.03WA 118
    rs1854452691,2
    --38474051(+) CTTAGA/GGGGCC 1 -- int10--------
    rs1906923961,2
    --38474053(+) TAGGGG/TGCCTG 1 -- int10--------
    rs1142046271,2
    C,F--38474148(+) CTGTCG/ATTCAG 1 -- ut311Minor allele frequency- A:0.03WA 118

    HapMap Linkage Disequilibrium report for SLC16A8 (38474141 - 38480100 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for SLC16A8:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv471198CNV Loss18288195
    nsv915053CNV Loss21882294
    nsv915035CNV Loss21882294
    nsv834193CNV Loss17160897
    nsv527871CNV Loss19592680
    nsv834194CNV Loss17160897
    dgv4969n71CNV Loss21882294
    dgv4968n71CNV Loss21882294
    nsv915054CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610409    OMIM disorders: --

    2 diseases for SLC16A8:    About MalaCards
    hyperparathyroidism    retinitis


    SLC16A8 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC16A8
    Human Genome Epidemiology (HuGE) Navigator: SLC16A8 (1 document)

    Export disorders for SLC16A8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC16A8 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with SLC16A8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning of the human monocarboxylate transporter MCT3 gene: localization to chromosome 22q12.3-q13.2. (PubMed id 10493836)1, 2, 3, 9 Yoon H.... Philp N.J. (1999)
    2. L-type voltage-dependent calcium channel alpha subuni t 1C is a novel candidate gene associated with secondary hyperparathyroidism: a n application of haplotype-based analysis for multiple linked single nucleotide polymorphisms. (PubMed id 20424473)1, 4 Yokoyama K....Hosoya T. (2010)
    3. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
    4. Seven new loci associated with age-related macular deg eneration. (PubMed id 23455636)1 Fritsche L.G....Abecasis G.R. (2013)
    5. Glucose affects monocarboxylate cotransporter (MCT) 1 expression during mouse preimplantation development. (PubMed id 16514190)7 Jansen S....Kaye P.L. (2006)
    6. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
    7. Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70). (PubMed id 15917240)1 Wilson M.C....Halestrap A.P. (2005)
    8. The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. (PubMed id 12739169)1 Halestrap A.P. and Meredith D. (2004)
    9. Polarized expression of monocarboxylate transporters in human retinal pigment epithelium and ARPE-19 cells. (PubMed id 12657613)1 Philp N.J....Hjelmeland L.M. (2003)
    10. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23539 HGNC: 16270 AceView: SLC16A8 Ensembl:ENSG00000100156 euGenes: HUgn23539
    ECgene: SLC16A8 H-InvDB: SLC16A8

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC16A8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC16A8 gene:
    Search GeneIP for patents involving SLC16A8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

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