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Aliases for SLC16A14 Gene

Aliases for SLC16A14 Gene

  • Solute Carrier Family 16, Member 14 2 3
  • Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 14 2 3
  • Monocarboxylic Acid Transporter 14 2 3
  • Solute Carrier Family 16 Member 14 3 4
  • MCT 14 3 4
  • MCT14 3 4
  • Solute Carrier Family 16, Member 14 (Monocarboxylic Acid Transporter 14) 3
  • Monocarboxylate Transporter 14 3

External Ids for SLC16A14 Gene

Previous GeneCards Identifiers for SLC16A14 Gene

  • GC02M231102
  • GC02M230725
  • GC02M230607
  • GC02M230899
  • GC02M222739

Summaries for SLC16A14 Gene

GeneCards Summary for SLC16A14 Gene

SLC16A14 (Solute Carrier Family 16, Member 14) is a Protein Coding gene. GO annotations related to this gene include symporter activity. An important paralog of this gene is SLC16A11.

UniProtKB/Swiss-Prot for SLC16A14 Gene

  • Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC16A14 Gene

Genomics for SLC16A14 Gene

Regulatory Elements for SLC16A14 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SLC16A14 Gene

Start:
230,034,974 bp from pter
End:
230,068,999 bp from pter
Size:
34,026 bases
Orientation:
Minus strand

Genomic View for SLC16A14 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC16A14 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC16A14 Gene

Proteins for SLC16A14 Gene

  • Protein details for SLC16A14 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7RTX9-MOT14_HUMAN
    Recommended name:
    Monocarboxylate transporter 14
    Protein Accession:
    Q7RTX9
    Secondary Accessions:
    • A8KA08
    • Q53R92
    • Q96NI7

    Protein attributes for SLC16A14 Gene

    Size:
    510 amino acids
    Molecular mass:
    56254 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SLC16A14 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLC16A14 Gene

Proteomics data for SLC16A14 Gene at MOPED

Post-translational modifications for SLC16A14 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC16A14 Gene

No data available for DME Specific Peptides for SLC16A14 Gene

Domains for SLC16A14 Gene

Gene Families for SLC16A14 Gene

Protein Domains for SLC16A14 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q7RTX9

UniProtKB/Swiss-Prot:

MOT14_HUMAN :
  • Q7RTX9
Family:
  • Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
genes like me logo Genes that share domains with SLC16A14: view

Function for SLC16A14 Gene

Molecular function for SLC16A14 Gene

UniProtKB/Swiss-Prot Function: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity).

Gene Ontology (GO) - Molecular Function for SLC16A14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008028 monocarboxylic acid transmembrane transporter activity IBA --
GO:0015293 symporter activity IEA --
genes like me logo Genes that share ontologies with SLC16A14: view

Animal Model Products

CRISPR Products

miRNA for SLC16A14 Gene

miRTarBase miRNAs that target SLC16A14

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC16A14

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SLC16A14 Gene

Localization for SLC16A14 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC16A14 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLC16A14 Gene COMPARTMENTS Subcellular localization image for SLC16A14 gene
Compartment Confidence
plasma membrane 5
cytosol 1
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for SLC16A14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with SLC16A14: view

Pathways for SLC16A14 Gene

SuperPathways for SLC16A14 Gene

No Data Available

Interacting Proteins for SLC16A14 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000295190%0d%0a9606.ENSP00000290429%0d%0a
Selected Interacting proteins: ENSP00000295190 Q7RTX9-MOT14_HUMAN for SLC16A14 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for SLC16A14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015718 monocarboxylic acid transport IBA --
GO:0034220 ion transmembrane transport IBA --
GO:0055085 transmembrane transport --
genes like me logo Genes that share ontologies with SLC16A14: view

No data available for Pathways by source for SLC16A14 Gene

Transcripts for SLC16A14 Gene

Unigene Clusters for SLC16A14 Gene

Solute carrier family 16, member 14 (monocarboxylic acid transporter 14):
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC16A14

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC16A14 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8
SP1: - - - -
SP2: -
SP3: - -
SP4:

Relevant External Links for SLC16A14 Gene

GeneLoc Exon Structure for
SLC16A14
ECgene alternative splicing isoforms for
SLC16A14

Expression for SLC16A14 Gene

mRNA expression in normal human tissues for SLC16A14 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for SLC16A14 Gene

SOURCE GeneReport for Unigene cluster for SLC16A14 Gene Hs.504317

genes like me logo Genes that share expressions with SLC16A14: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SLC16A14 Gene

Orthologs for SLC16A14 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC16A14 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC16A14 35
  • 99.48 (n)
  • 99.22 (a)
SLC16A14 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SLC16A14 35
  • 85.1 (n)
  • 89.02 (a)
SLC16A14 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLC16A14 35
  • 81.96 (n)
  • 86.16 (a)
SLC16A14 36
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slc16a14 35
  • 82.81 (n)
  • 87.45 (a)
Slc16a14 16
Slc16a14 36
  • 87 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SLC16A14 36
  • 82 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Slc16a14 35
  • 84.41 (n)
  • 92.13 (a)
chicken
(Gallus gallus)
Aves SLC16A14 35
  • 72.51 (n)
  • 74.8 (a)
SLC16A14 36
  • 74 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SLC16A14 36
  • 73 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia slc16a14 35
  • 66.33 (n)
  • 67.13 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003206 35
  • 46.49 (n)
  • 34.24 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13907 35
  • 47.82 (n)
  • 37.78 (a)
worm
(Caenorhabditis elegans)
Secernentea pes-22 35
  • 43.06 (n)
  • 30.79 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 23 (a)
OneToMany
Species with no ortholog for SLC16A14:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for SLC16A14 Gene

ENSEMBL:
Gene Tree for SLC16A14 (if available)
TreeFam:
Gene Tree for SLC16A14 (if available)

Paralogs for SLC16A14 Gene

Selected SIMAP similar genes for SLC16A14 Gene using alignment to 6 proteins:

Pseudogenes.org Pseudogenes for SLC16A14 Gene

genes like me logo Genes that share paralogs with SLC16A14: view

Variants for SLC16A14 Gene

Sequence variations from dbSNP and Humsavar for SLC16A14 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs3923567 -- 230,065,521(-) TCCCA(G/T)CACTT intron-variant
rs4246639 -- 230,056,176(+) ACACA(C/T)GTGCC intron-variant
rs4246640 -- 230,066,850(+) TCGAA(A/C)CTCTG intron-variant
rs4246641 -- 230,067,007(+) AGCAC(A/G)AAGCT intron-variant
rs4263100 -- 230,060,172(+) GCAGG(A/G)GCTAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SLC16A14 Gene

Variant ID Type Subtype PubMed ID
dgv164e55 CNV Gain 17911159
nsv460118 CNV Gain 19166990
nsv875941 CNV Loss 21882294

Relevant External Links for SLC16A14 Gene

HapMap Linkage Disequilibrium report
SLC16A14

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC16A14 Gene

Disorders for SLC16A14 Gene

No disorders were found for SLC16A14 Gene.

No data available for UniProtKB/Swiss-Prot for SLC16A14 Gene

Publications for SLC16A14 Gene

  1. The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. (PMID: 12739169) Halestrap A.P. … Meredith D. (Pflugers Arch. 2004) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4

Products for SLC16A14 Gene

Sources for SLC16A14 Gene

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