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Aliases for SLC16A14 Gene

Aliases for SLC16A14 Gene

  • Solute Carrier Family 16 Member 14 2 3 4 5
  • Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 14 2 3
  • Monocarboxylic Acid Transporter 14 2 3
  • MCT 14 3 4
  • MCT14 3 4
  • Solute Carrier Family 16, Member 14 (Monocarboxylic Acid Transporter 14) 3
  • Solute Carrier Family 16, Member 14 2

External Ids for SLC16A14 Gene

Previous GeneCards Identifiers for SLC16A14 Gene

  • GC02M231102
  • GC02M230725
  • GC02M230607
  • GC02M230899
  • GC02M222739

Summaries for SLC16A14 Gene

GeneCards Summary for SLC16A14 Gene

SLC16A14 (Solute Carrier Family 16 Member 14) is a Protein Coding gene. GO annotations related to this gene include symporter activity and monocarboxylic acid transmembrane transporter activity. An important paralog of this gene is SLC16A11.

UniProtKB/Swiss-Prot for SLC16A14 Gene

  • Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC16A14 Gene

Genomics for SLC16A14 Gene

Regulatory Elements for SLC16A14 Gene

Enhancers for SLC16A14 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SLC16A14 on UCSC Golden Path with GeneCards custom track

Promoters for SLC16A14 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SLC16A14 on UCSC Golden Path with GeneCards custom track

Genomic Location for SLC16A14 Gene

230,034,974 bp from pter
230,068,999 bp from pter
34,026 bases
Minus strand

Genomic View for SLC16A14 Gene

Genes around SLC16A14 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC16A14 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC16A14 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC16A14 Gene

Proteins for SLC16A14 Gene

  • Protein details for SLC16A14 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Monocarboxylate transporter 14
    Protein Accession:
    Secondary Accessions:
    • A8KA08
    • Q53R92
    • Q96NI7

    Protein attributes for SLC16A14 Gene

    510 amino acids
    Molecular mass:
    56254 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SLC16A14 Gene


neXtProt entry for SLC16A14 Gene

Proteomics data for SLC16A14 Gene at MOPED

Post-translational modifications for SLC16A14 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC16A14 Gene

Antibody Products

No data available for DME Specific Peptides for SLC16A14 Gene

Domains & Families for SLC16A14 Gene

Gene Families for SLC16A14 Gene

Protein Domains for SLC16A14 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
  • Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
genes like me logo Genes that share domains with SLC16A14: view

Function for SLC16A14 Gene

Molecular function for SLC16A14 Gene

UniProtKB/Swiss-Prot Function:
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity).
genes like me logo Genes that share phenotypes with SLC16A14: view

Animal Model Products

  • Taconic Biosciences Mouse Models for SLC16A14

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SLC16A14 Gene

Localization for SLC16A14 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC16A14 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SLC16A14 Gene COMPARTMENTS Subcellular localization image for SLC16A14 gene
Compartment Confidence
plasma membrane 5
cytosol 2
endoplasmic reticulum 2

Gene Ontology (GO) - Cellular Components for SLC16A14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
genes like me logo Genes that share ontologies with SLC16A14: view

Pathways & Interactions for SLC16A14 Gene

SuperPathways for SLC16A14 Gene

No Data Available

Interacting Proteins for SLC16A14 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000295190 Q7RTX9-MOT14_HUMAN for SLC16A14 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for SLC16A14 Gene


No data available for Pathways by source and SIGNOR curated interactions for SLC16A14 Gene

Drugs & Compounds for SLC16A14 Gene

No Compound Related Data Available

Transcripts for SLC16A14 Gene

Unigene Clusters for SLC16A14 Gene

Solute carrier family 16, member 14 (monocarboxylic acid transporter 14):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC16A14 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8
SP1: - - - -
SP2: -
SP3: - -

Relevant External Links for SLC16A14 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC16A14 Gene

mRNA expression in normal human tissues for SLC16A14 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for SLC16A14 Gene

SOURCE GeneReport for Unigene cluster for SLC16A14 Gene Hs.504317

genes like me logo Genes that share expression patterns with SLC16A14: view

Protein tissue co-expression partners for SLC16A14 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SLC16A14 Gene

Orthologs for SLC16A14 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC16A14 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SLC16A14 35
  • 85.1 (n)
  • 89.02 (a)
SLC16A14 36
  • 89 (a)
(Canis familiaris)
Mammalia SLC16A14 35
  • 81.96 (n)
  • 86.16 (a)
SLC16A14 36
  • 85 (a)
(Mus musculus)
Mammalia Slc16a14 35
  • 82.81 (n)
  • 87.45 (a)
Slc16a14 16
Slc16a14 36
  • 87 (a)
(Pan troglodytes)
Mammalia SLC16A14 35
  • 99.48 (n)
  • 99.22 (a)
SLC16A14 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Slc16a14 35
  • 84.41 (n)
  • 92.13 (a)
(Monodelphis domestica)
Mammalia SLC16A14 36
  • 82 (a)
(Gallus gallus)
Aves SLC16A14 35
  • 72.51 (n)
  • 74.8 (a)
SLC16A14 36
  • 74 (a)
(Anolis carolinensis)
Reptilia SLC16A14 36
  • 73 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia slc16a14 35
  • 66.33 (n)
  • 67.13 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003206 35
  • 46.49 (n)
  • 34.24 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13907 35
  • 47.82 (n)
  • 37.78 (a)
(Caenorhabditis elegans)
Secernentea pes-22 35
  • 43.06 (n)
  • 30.79 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 23 (a)
Species with no ortholog for SLC16A14:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for SLC16A14 Gene

Gene Tree for SLC16A14 (if available)
Gene Tree for SLC16A14 (if available)

Paralogs for SLC16A14 Gene

(7) SIMAP similar genes for SLC16A14 Gene using alignment to 6 proteins: Pseudogenes for SLC16A14 Gene

genes like me logo Genes that share paralogs with SLC16A14: view

Variants for SLC16A14 Gene

Sequence variations from dbSNP and Humsavar for SLC16A14 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs4972927 -- 230,051,229(+) GATCA(C/T)GGCTC intron-variant
rs4972928 -- 230,056,545(+) accac(C/T)gtgcc intron-variant
rs4972929 -- 230,063,453(+) AAGAT(A/T)CAGTT intron-variant
rs4972930 -- 230,063,585(+) ATCAA(G/T)AATAA intron-variant
rs4973245 -- 230,039,159(+) TATCT(A/G)TTTAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC16A14 Gene

Variant ID Type Subtype PubMed ID
dgv164e55 CNV Gain 17911159
nsv460118 CNV Gain 19166990
nsv875941 CNV Loss 21882294

Variation tolerance for SLC16A14 Gene

Residual Variation Intolerance Score: 49.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.67; 31.96% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SLC16A14 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC16A14 Gene

Disorders for SLC16A14 Gene

Relevant External Links for SLC16A14

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SLC16A14 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLC16A14 Gene

Publications for SLC16A14 Gene

  1. The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. (PMID: 12739169) Halestrap A.P. … Meredith D. (Pflugers Arch. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SLC16A14 Gene

Sources for SLC16A14 Gene