SLC16A13 Gene
protein-coding GIFtS: 39
GCID: GC17P006939
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solute carrier family 16, member 13 (monocarboxylic acid...(Previous names: solute carrier family 16 (monocarboxylic acid transporters),...)
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Aliases
for SLC16A13 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Solute Carrier Family 16, Member 13 (Monocarboxylic Acid Transporter 13)1 2 | | MCT131 2 3 | | Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 131 2 | | Solute Carrier Family 16 Member 132 3 | | MCT 132 3 | | Monocarboxylate Transporter 132 |
Export aliases for SLC16A13 gene to outside databasesPrevious GC identifers: GC17P007140 GC17P006882 GC17P006883 |
Summaries
for SLC16A13 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: MOT13_HUMAN, Q7RTY0Function: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of manymonocarboxylates (By similarity)
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Genomic Views
for SLC16A13 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SLC16A13 gene promoter:
E2F-4 E2F-3a Spz1 Sp1 Nkx2-5 E2F-2 POU3F2 AREB6 E2F E2F-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SLC16A13
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC16A13 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p13.1 Ensembl cytogenetic band: 17p13.1 HGNC cytogenetic band: 17p13.1SLC16A13 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P006939: view genomic region
(about GC identifiers)
Start:
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6,939,394 bp from pter |
End:
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6,943,440 bp from pter |
Size:
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4,047 bases |
Orientation:
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plus strand |
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Proteins
for SLC16A13 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MOT13_HUMAN, Q7RTY0 (See
protein sequence)Recommended Name: Monocarboxylate transporter 13 Size: 426 amino acids; 44992 Da
Subcellular location: Cell membrane; Multi-pass membrane protein (By similarity)
Secondary accessions: A3KMG3 A5PKU5 Q2VP92Explore the universe of human proteins at neXtProt for SLC16A13: NX_Q7RTY0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7RTY0
SLC16A13 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_963860.1
ENSEMBL proteins: ENSP00000309751
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
SLC16A13 for ontologies About GeneDecksing
SLC16A13 Antibody Products:
Assay Products for SLC16A13: |
Protein
Domains /
Families
for SLC16A13 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SLC16A13 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q7RTY0ProtoNet protein and cluster: Q7RTY0 UniProtKB/Swiss-Prot: MOT13_HUMAN, Q7RTY0Similarity: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family |
Function
for SLC16A13 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MOT13_HUMAN, Q7RTY0Function: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of manymonocarboxylates (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC16A13 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC16A13
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SLC16A13 (NM_201566) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC16A13 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC16A13 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC16A13 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0015293 | symporter activity |
IEA | -- |
SLC16A13 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SLC16A13:
|
Pathways & Interactions
for SLC16A13 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC16A13
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for SLC16A13 (ENSP000003097514) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for SLC16A13 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SLC16A13
Search CenterWatch for drugs/clinical trials and news about SLC16A13 / MOT13
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Transcripts
for SLC16A13 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SLC16A13 gene: NM_201566.2 Unigene Cluster for SLC16A13: Solute carrier family 16, member 13 (monocarboxylic acid transporter 13) Hs.448010 [show with all ESTs]Unigene Representative Sequence: BC1426182 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000308027(uc002geh.3) ENST00000575844
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC16A13 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC16A13
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SLC16A13 (NM_201566) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC16A13 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC16A13 |
Additional cDNA sequence: BC109286.1 BC131739.1 BC142618.1 1 DOTS entry: DT.91833624 4 AceView cDNA sequences: BU538223 NM_201566 BN000145 BE075065
GeneLoc Exon Structure
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Expression
for SLC16A13 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SLC16A13 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCCCCTTCCT
About this image
See SLC16A13 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.448010
SABiosciences Custom PCR Arrays for SLC16A13
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC16A13
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC16A13 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC16A13 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC16A13 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC16A13 |
Orthologs
for SLC16A13 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SLC16A13 gene from 4/14 species (see all 14) About this table
ENSEMBL Gene Tree for SLC16A13 (if available)
TreeFam Gene Tree for SLC16A13 (if available) |
Paralogs
for SLC16A13 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SLC16A13 gene
- SLC16A42 SLC16A32 SLC16A52 SLC16A102 SLC16A112 SLC16A22 SLC16A62 SLC16A82
- SLC16A142 SLC16A72 SLC16A12 SLC16A122 SLC16A92
9 SIMAP similar genes for SLC16A13 using alignment to 1 protein entry: MOT13_HUMAN:SLC16A11 SLC16A7 SLC16A3 SLC16A12 SLC16A5 SLC16A1
SLC16A2 SLC16A8 SLC16A6
SLC16A13 for paralogs About GeneDecksing
|
Genomic Variants
for SLC16A13 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SLC16A13 (6939394 - 6943440 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SLC16A13
1 Indel: 25913 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC16A13 |
|
Disorders
/ Diseases
for SLC16A13 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for SLC16A13 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SLC16A13 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SLC16A13) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. (PubMed id 12739169)1, 2 Halestrap A.P. and Meredith D. (2004)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for SLC16A13 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing SLC16A13 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SLC16A13 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SLC16A13 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SLC16A13 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for SLC16A13 gene:
Search GeneIP for patents involving SLC16A13
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SLC16A13 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SLC16A13 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC16A13 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC16A13 | | | OriGene Protein Over-expression Lysate for SLC16A13 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SLC16A13 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC16A13 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC16A13 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SLC16A13 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC16A13 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC16A13 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC16A13 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC16A13 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC16A13 |
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 | | | SLC16A13 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC16A13 |
|  |  |  | | | | Search ThermoFisher Antibodies for SLC16A13 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC16A13 |
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