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Aliases for SLC16A13 Gene

Aliases for SLC16A13 Gene

  • Solute Carrier Family 16, Member 13 2 3
  • Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 13 2 3
  • Monocarboxylic Acid Transporter 13 2 3
  • Solute Carrier Family 16 Member 13 3 4
  • MCT 13 3 4
  • MCT13 3 4
  • Solute Carrier Family 16, Member 13 (Monocarboxylic Acid Transporter 13) 3
  • Monocarboxylate Transporter 13 3

External Ids for SLC16A13 Gene

Previous GeneCards Identifiers for SLC16A13 Gene

  • GC17P007140
  • GC17P006882
  • GC17P006883
  • GC17P006939

Summaries for SLC16A13 Gene

GeneCards Summary for SLC16A13 Gene

SLC16A13 (Solute Carrier Family 16, Member 13) is a Protein Coding gene. GO annotations related to this gene include symporter activity. An important paralog of this gene is SLC16A11.

UniProtKB/Swiss-Prot for SLC16A13 Gene

  • Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC16A13 Gene

Genomics for SLC16A13 Gene

Regulatory Elements for SLC16A13 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SLC16A13 Gene

Start:
7,036,075 bp from pter
End:
7,040,121 bp from pter
Size:
4,047 bases
Orientation:
Plus strand

Genomic View for SLC16A13 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC16A13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC16A13 Gene

Proteins for SLC16A13 Gene

  • Protein details for SLC16A13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7RTY0-MOT13_HUMAN
    Recommended name:
    Monocarboxylate transporter 13
    Protein Accession:
    Q7RTY0
    Secondary Accessions:
    • A3KMG3
    • A5PKU5
    • Q2VP92

    Protein attributes for SLC16A13 Gene

    Size:
    426 amino acids
    Molecular mass:
    44992 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLC16A13 Gene

Proteomics data for SLC16A13 Gene at MOPED

Post-translational modifications for SLC16A13 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC16A13 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for SLC16A13 Gene

Domains for SLC16A13 Gene

Gene Families for SLC16A13 Gene

Protein Domains for SLC16A13 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SLC16A13 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7RTY0

UniProtKB/Swiss-Prot:

MOT13_HUMAN :
  • Q7RTY0
Family:
  • Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
genes like me logo Genes that share domains with SLC16A13: view

Function for SLC16A13 Gene

Molecular function for SLC16A13 Gene

UniProtKB/Swiss-Prot Function:
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity).

Gene Ontology (GO) - Molecular Function for SLC16A13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008028 monocarboxylic acid transmembrane transporter activity IBA --
GO:0015293 symporter activity IEA --
genes like me logo Genes that share ontologies with SLC16A13: view

Phenotypes for SLC16A13 Gene

GenomeRNAi human phenotypes for SLC16A13:
genes like me logo Genes that share phenotypes with SLC16A13: view

Animal Model Products

CRISPR Products

miRNA for SLC16A13 Gene

miRTarBase miRNAs that target SLC16A13

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC16A13

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for SLC16A13 Gene

Localization for SLC16A13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC16A13 Gene

Golgi apparatus membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLC16A13 Gene COMPARTMENTS Subcellular localization image for SLC16A13 gene
Compartment Confidence
plasma membrane 5
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for SLC16A13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane IEA --
GO:0005794 Golgi apparatus IDA 24390345
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with SLC16A13: view

Pathways for SLC16A13 Gene

SuperPathways for SLC16A13 Gene

No Data Available

Interacting Proteins for SLC16A13 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000309751%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000309751 for SLC16A13 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for SLC16A13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015718 monocarboxylic acid transport IBA --
GO:0034220 ion transmembrane transport IBA --
GO:0055085 transmembrane transport --
genes like me logo Genes that share ontologies with SLC16A13: view

No data available for Pathways by source for SLC16A13 Gene

Transcripts for SLC16A13 Gene

mRNA/cDNA for SLC16A13 Gene

(3) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLC16A13 Gene

Solute carrier family 16, member 13 (monocarboxylic acid transporter 13):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC16A13

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC16A13 Gene

No ASD Table

Relevant External Links for SLC16A13 Gene

GeneLoc Exon Structure for
SLC16A13
ECgene alternative splicing isoforms for
SLC16A13

Expression for SLC16A13 Gene

mRNA expression in normal human tissues for SLC16A13 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLC16A13 Gene

This gene is overexpressed in Liver (14.8) and Kidney - Cortex (5.3).

SOURCE GeneReport for Unigene cluster for SLC16A13 Gene Hs.448010

genes like me logo Genes that share expressions with SLC16A13: view

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for SLC16A13 Gene

Orthologs for SLC16A13 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SLC16A13 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SLC16A13 35
  • 87.72 (n)
  • 89.2 (a)
SLC16A13 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLC16A13 35
  • 86.12 (n)
  • 87.29 (a)
SLC16A13 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slc16a13 35
  • 88.18 (n)
  • 87.32 (a)
Slc16a13 16
Slc16a13 36
  • 87 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia SLC16A13 35
  • 99.61 (n)
  • 99.77 (a)
SLC16A13 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Slc16a13 35
  • 88.58 (n)
  • 88.5 (a)
oppossum
(Monodelphis domestica)
Mammalia SLC16A13 36
  • 77 (a)
OneToOne
chicken
(Gallus gallus)
Aves SLC16A13 36
  • 44 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SLC16A13 36
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia slc16a13 35
  • 58.95 (n)
  • 54.24 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC793210 35
  • 57.99 (n)
  • 55.41 (a)
SLC16A13 36
  • 43 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 27 (a)
OneToMany
Species with no ortholog for SLC16A13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SLC16A13 Gene

ENSEMBL:
Gene Tree for SLC16A13 (if available)
TreeFam:
Gene Tree for SLC16A13 (if available)

Paralogs for SLC16A13 Gene

Selected SIMAP similar genes for SLC16A13 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SLC16A13: view

Variants for SLC16A13 Gene

Sequence variations from dbSNP and Humsavar for SLC16A13 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs312455 -- 7,034,765(-) tgaga(C/T)ggagt upstream-variant-2KB
rs312456 -- 7,035,016(-) GTGTG(C/T)AGTCT upstream-variant-2KB
rs312457 -- 7,037,074(-) gtgcc(C/T)ggccA intron-variant
rs312458 -- 7,037,412(-) CTTTT(A/G)CACTC intron-variant
rs1967272 -- 7,039,384(+) GAACC(C/T)GGGAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC16A13 Gene

Variant ID Type Subtype PubMed ID
esv2422288 CNV Deletion 17116639
nsv907634 CNV Loss 21882294
nsv457659 CNV Loss 19166990
nsv512475 CNV Loss 21212237
esv2672389 CNV Deletion 23128226
esv1405948 CNV Deletion 17803354
esv2715594 CNV Deletion 23290073
esv2665042 CNV Deletion 23128226

Relevant External Links for SLC16A13 Gene

HapMap Linkage Disequilibrium report
SLC16A13

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC16A13 Gene

Disorders for SLC16A13 Gene

UniProtKB/Swiss-Prot

MOT13_HUMAN
  • Diabetes mellitus, non-insulin-dependent (NIDDM) [MIM:125853]: A multifactorial disorder of glucose homeostasis caused by a lack of sensitivity to the bodys own insulin. Affected individuals usually have an obese body habitus and manifestations of a metabolic syndrome characterized by diabetes, insulin resistance, hypertension and hypertriglyceridemia. The disease results in long-term complications that affect the eyes, kidneys, nerves, and blood vessels. {ECO:0000269 PubMed:24390345}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

No disorders were found for SLC16A13 Gene.

No data available for MalaCards , OMIM , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SLC16A13 Gene

Publications for SLC16A13 Gene

  1. The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. (PMID: 12739169) Halestrap A.P. … Meredith D. (Pflugers Arch. 2004) 3 4
  2. Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. (PMID: 24390345) . … Altshuler D. (Nature 2014) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  5. Genome-wide association study identifies three novel loci for type 2 diabetes. (PMID: 23945395) Hara K. … Kadowaki T. (Hum. Mol. Genet. 2014) 3

Products for SLC16A13 Gene

Sources for SLC16A13 Gene

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