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SLC16A10 Gene

protein-coding   GIFtS: 57
GCID: GC06P111454

Solute Carrier Family 16 (Aromatic Amino Acid Transporter),...

(Previous names: solute carrier family 16 (monocarboxylic acid transporters),...)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 16 (Aromatic Amino Acid Transporter), Member
101 2
     MCT 102 3
TAT12 3 5     T-Type Amino Acid Transporter 12 3
Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 101 2     PRO08132
Aromatic Amino Acid Transporter 12 3     Monocarboxylate Transporter 102
Solute Carrier Family 16 Member 102 3     Solute Carrier Family 16, Member 10 (Aromatic Amino Acid Transporter)2
MCT102 3     

External Ids:    HGNC: 170271   Entrez Gene: 1172472   Ensembl: ENSG000001123947   OMIM: 6075505   UniProtKB: Q8TF713   

Export aliases for SLC16A10 gene to outside databases

Previous GC identifers: GC06P111244 GC06P111431 GC06P111515 GC06P108979


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC16A10 Gene:
SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent
transport of aromatic amino acids across the plasma membrane.(supplied by OMIM, Apr 2004)

GeneCards Summary for SLC16A10 Gene:
SLC16A10 (solute carrier family 16 (aromatic amino acid transporter), member 10) is a protein-coding gene. Diseases associated with SLC16A10 include allan-herndon-dudley syndrome, and cystitis. An important paralog of this gene is SLC16A2.

UniProtKB/Swiss-Prot: MOT10_HUMAN, Q8TF71
Function: Sodium-independent transporter that mediates the update of aromatic acid. Can function as a net efflux
pathway for aromatic amino acids in the basosolateral epithelial cells (By similarity)

Gene Wiki entry for SLC16A10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NT_025741.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC16A10 gene promoter:
         HFH-3   AML1a   FOXD3   HNF-1A   YY1   C/EBPalpha   FOXI1   HNF-1   ZID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC16A10 promoter sequence
   Search Chromatin IP Primers for SLC16A10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC16A10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q21-q22   Ensembl cytogenetic band:  6q21   HGNC cytogenetic band: 6q21-q22

SLC16A10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC16A10 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P111454:  view genomic region     (about GC identifiers)

Start:
111,408,781 bp from pter      End:
111,552,397 bp from pter
Size:
143,617 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: MOT10_HUMAN, Q8TF71 (See protein sequence)
Recommended Name: Monocarboxylate transporter 10  
Size: 515 amino acids; 55493 Da
Sequence caution: Sequence=AAH17968.1; Type=Erroneous initiation;
Secondary accessions: B3KWY0 Q6ZMG0 Q8WVI5

Explore the universe of human proteins at neXtProt for SLC16A10: NX_Q8TF71

Explore proteomics data for SLC16A10 at MOPED

Post-translational modifications: 

  • Not N-glycosylated (By similarity)1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SLC16A10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_061063.2  
    ENSEMBL proteins: 
     ENSP00000357844   ENSP00000387501   ENSP00000399601   ENSP00000357843  
    Reactome Protein details: Q8TF71

    SLC16A10 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Monocarboxylate transporter 10
    SLC16 family of monocarboxylate transporters

    3 InterPro protein domains:
     IPR011701 MFS
     IPR020846 MFS_dom
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry Q8TF71

    ProtoNet protein and cluster: Q8TF71

    UniProtKB/Swiss-Prot: MOT10_HUMAN, Q8TF71
    Similarity: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family


    SLC16A10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MOT10_HUMAN, Q8TF71
    Function: Sodium-independent transporter that mediates the update of aromatic acid. Can function as a net efflux
    pathway for aromatic amino acids in the basosolateral epithelial cells (By similarity)

    Phenotypes:
         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Slc16a10):

     behavior/neurological  growth/size/body  homeostasis/metabolism  renal/urinary system 

    SLC16A10 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC16A10
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    miRNA
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    miRTarBase miRNAs that target SLC16A10:
    hsa-mir-21-5p (MIRT002409)

    Block miRNA regulation of human, mouse, rat SLC16A10 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SLC16A10 (see all 15):
    hsa-miR-98 hsa-let-7d hsa-miR-513a-5p hsa-miR-27a hsa-miR-622 hsa-miR-202 hsa-let-7c hsa-let-7i
    SwitchGear 3'UTR luciferase reporter plasmidSLC16A10 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC16A10


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MOT10_HUMAN, Q8TF71: Cell membrane; Multi-pass membrane protein (By similarity). Basolateral cell membrane (By
    similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral component of membrane IEA--
    GO:0016323basolateral plasma membrane TAS15918515

    SLC16A10 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SLC16A10 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    SLC-mediated transmembrane transport0.47
    Transport of inorganic cations/anions and amino acids/oligopeptides0.38
    Transmembrane transport of small molecules0.47
    Amino acid transport across the plasma membrane0.32
    2Thyroid hormone signaling pathway
    Thyroid hormone signaling pathway
    3Protein digestion and absorption
    Protein digestion and absorption

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for SLC16A10
        Amino acid transport across the plasma membrane


    2 Kegg Pathways  (Kegg details for SLC16A10):
        Thyroid hormone signaling pathway
    Protein digestion and absorption


    SLC16A10 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC16A10
    Interactions:

        Search GeneGlobe Interaction Network for SLC16A10

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for SLC16A10 (Q8TF713 ENSP000003578444) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RACGAP1Q9H0H53, ENSP000003098714I2D: score=1 STRING: ENSP00000309871
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport TAS--
    GO:0006865amino acid transport TAS--
    GO:0015801aromatic amino acid transport TAS15918515
    GO:0055085transmembrane transport TAS--

    SLC16A10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC16A10 (MOT10)

    1 HMDB Compound for SLC16A10    About this table
    CompoundSynonyms CAS #PubMed Ids
    SodiumSodium (see all 2)7440-23-5--

    Selected DrugBank Compounds for SLC16A10 (see all 35)    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    D-Phenylalanine-- 673-06-3transportersubstrate inhibitor11827462 11278508
    Glycine2-Aminoacetic acid (see all 4)56-40-6transportersubstrate inhibitor11827462 11278508
    L-Glutamic Acid(2S)-2-Aminopentanedioic acid (see all 15)56-86-0transportersubstrate inhibitor11827462 11278508
    L-Histidine(S)-4-(2-Amino-2-carboxyethyl)imidazole (see all 7)71-00-1transportersubstrate inhibitor11827462 11278508
    L-Leucine(2S)-2-Amino-4-methylpentanoic acid (see all 16)61-90-5transporterinhibitor11827462 11278508
    L-Lysine(S)-2,6-diaminohexanoic acid (see all 6)56-87-1transportersubstrate inhibitor11827462 11278508
    L-Phenylalanine(S)-alpha-Amino-beta-phenylpropionic acid (see all 4)63-91-2transporterinhibitor11827462 11278508
    L-Tryptophan(-)-Tryptophan (see all 14)73-22-3transporterinhibitor11827462 11278508
    L-Tyrosine2-Amino-3-(p-hydroxyphenyl)propionic acid (see all 3)60-18-4transporterinhibitor11827462 11278508
    Lactic Acid-- 50-21-5transportersubstrate inhibitor11827462 11278508



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SLC16A10 gene: 
    NM_018593.4  

    Unigene Cluster for SLC16A10:

    Solute carrier family 16, member 10 (aromatic amino acid transporter)
    Hs.591327  [show with all ESTs]
    Unigene Representative Sequence: NM_018593
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368851(uc003pur.4 uc003pus.3) ENST00000439288 ENST00000465319
    ENST00000419619 ENST00000368850(uc003put.3)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SLC16A10 (see all 15):
    hsa-miR-98 hsa-let-7d hsa-miR-513a-5p hsa-miR-27a hsa-miR-622 hsa-miR-202 hsa-let-7c hsa-let-7i
    SwitchGear 3'UTR luciferase reporter plasmidSLC16A10 3' UTR sequence
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      QuantiTect SYBR Green Assays in human, mouse, rat SLC16A10
      QuantiFast Probe-based Assays in human, mouse, rat SLC16A10

    Additional mRNA sequence: 

    AB057445.1 AK126183.1 AK172789.1 BC017968.1 BC034031.1 BC066985.1 

    6 DOTS entries:

    DT.91733108  DT.311807  DT.40302867  DT.75106653  DT.99959363  DT.91687711 

    Selected AceView cDNA sequences (see all 54):

    AW058100 BF057228 AI373734 BF196337 AA001776 AI221043 AI910470 AA876069 
    BC034031 BF059424 AI111187 AK126183 AW196676 AI242847 BG498565 BX348982 
    CK820059 BM354092 N41980 CD251942 AW237016 D81852 BM997859 BX102123 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC16A10 expression in normal human tissues (normalized intensities)      SLC16A10 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SLC16A10 Expression
    About this image


    SLC16A10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 3 entries
             T-Cytotoxic Cells Peripheral Blood
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Choroid Plexus Progenitor Cells Choroid Plexus
             Choroid Plexus
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Human embryonic stem cells (family)
    SLC16A10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC16A10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.591327

    UniProtKB/Swiss-Prot: MOT10_HUMAN, Q8TF71
    Tissue specificity: Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC16A10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SLC16A10 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc16a101 , 5 solute carrier family 16 (monocarboxylic acid transporters), member 10 less1, 5 85.03(n)1
    84.77(a)1
      10 (21.48 cM)5
    724721  NM_001114332.11  NP_001107804.11 
     400335355 
    chicken
    (Gallus gallus)
    Aves SLC16A101 solute carrier family 16, member 10 (aromatic amino acid transporter) less 75.69(n)
    77.36(a)
      421753  XM_419783.4  XP_419783.3 
    lizard
    (Anolis carolinensis)
    Reptilia SLC16A106
    solute carrier family 16 (aromatic amino acid tran...
    70(a)
    1 ↔ 1
    1(192144331-192171512)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia slc16a101 solute carrier family 16, member 10 (aromatic amino acid transporter) less 69.39(n)
    72.73(a)
      100488837  XM_002936936.2  XP_002936982.1 
    zebrafish
    (Danio rerio)
    Actinopterygii slc16a101 solute carrier family 16, member 10 (aromatic amino acid transporter) less 67.46(n)
    72.27(a)
      566499  NM_001080028.1  NP_001073497.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta kar1 , 3 ommochrome biosynthesis monocarboxylic
    acid transporter less3
    karmoisin1
    45(a)3
    54.56(n)1
    45.77(a)1
      3 87C53
    458831  NM_143768.31  NP_652025.21 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_Y19D10A.121 CELE_Y19D10A.12 43.15(n)
    31.6(a)
      189489  NM_071254.2  NP_503655.2 


    ENSEMBL Gene Tree for SLC16A10 (if available)
    TreeFam Gene Tree for SLC16A10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC16A10 gene
    SLC16A22  
    9 SIMAP similar genes for SLC16A10 using alignment to 5 protein entries:     MOT10_HUMAN (see all proteins):
    SLC16A2    SLC16A12    SLC16A14    SLC16A3    SLC16A8    SLC16A9
    SLC16A5    SLC16A1    SLC16A7

    SLC16A10 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC16A10 (see all 2204)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1856857281,2
    --111406799(+) TGTGAC/TAGTTT 1 -- us2k10--------
    rs1905485411,2
    --111406857(+) TAATGA/GGTATT 1 -- us2k10--------
    rs1930301811,2
    --111406888(+) GGATTC/TGTCTA 1 -- us2k10--------
    rs1845508421,2
    --111406957(+) AAGTAA/CCATTT 1 -- us2k10--------
    rs1885727491,2
    --111407006(+) AGGTAC/TTGTGT 1 -- us2k10--------
    rs1455851421,2
    --111407090(+) TACTAC/TGCATA 1 -- us2k10--------
    rs1381946891,2
    C--111407128(+) CTTCAA/CCTCCA 1 -- us2k10--------
    rs119666641,2
    C,F,H--111407204(+) tcattA/Gtttat 1 -- us2k1 tfbs34Minor allele frequency- G:0.02NS EA WA 392
    rs1428001011,2
    C--111407225(+) ACTTAC/TATCAG 1 -- us2k10--------
    rs119617561,2
    C,F,A,H--111407233(+) cagtaC/Ttgact 1 -- us2k15Minor allele frequency- T:0.02NS EA WA 534

    HapMap Linkage Disequilibrium report for SLC16A10 (111408781 - 111552397 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for SLC16A10:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2732574CNV Deletion23290073
    esv2661859CNV Deletion23128226
    nsv509149CNV Insertion20534489
    nsv5441CNV Insertion18451855
    nsv5440CNV Insertion18451855
    nsv886540CNV Loss21882294
    nsv886539CNV Gain21882294
    nsv886538CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC16A10
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 607550    OMIM disorders: --

    7 diseases for SLC16A10:    About MalaCards
    allan-herndon-dudley syndrome    cystitis    transitional cell carcinoma    choroiditis
    cerebritis    thyroiditis    malaria

    1 disease from the University of Copenhagen DISEASES database for SLC16A10:
    Allan-Herndon-Dudley syndrome

    SLC16A10 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC16A10
    Human Genome Epidemiology (HuGE) Navigator: SLC16A10 (2 documents)

    Export disorders for SLC16A10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

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    PubMed articles for SLC16A10 gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with SLC16A10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location. (PubMed id 11827462)1, 2, 3, 7, 9 Kim D.K.... Endou H. (Genomics 2002)
    2. Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. (PubMed id 11278508)1, 3, 7 Kim D.K....Endou H. (J. Biol. Chem. 2001)
    3. The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. (PubMed id 12739169)1, 9 Halestrap A.P. and Meredith D. (Pflugers Arch. 2004)
    4. Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule. (PubMed id 15918515)1, 9 Park S.Y.... Kim D.K. (Arch. Pharm. Res. 2005)
    5. Genome-wide association study identifies multiple loci influencing human serum metabolite levels. (PubMed id 22286219)1 Kettunen J....Ripatti S. (Nat. Genet. 2012)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    8. The expression of thyroid hormone transporters in the human fetal cerebral cortex during early development and in N-Tera-2 neurodifferentiation. (PubMed id 21486766)1 Chan S.Y....Kilby M.D. (J. Physiol. (Lond.) 2011)
    9. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    10. The thyroid hormone transporters MCT8 and MCT10 transport the affinity-label N-bromoacetyl-[(125)I]T3 but are not modified by it. (PubMed id 21315799)1 Visser W.E....Visser T.J. (Mol. Cell. Endocrinol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 117247 HGNC: 17027 AceView: SLC16A10 Ensembl:ENSG00000112394 euGenes: HUgn117247
    ECgene: SLC16A10 Kegg: 117247 H-InvDB: SLC16A10

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SLC16A10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for SLC16A10 gene:
    Search GeneIP for patents involving SLC16A10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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