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Aliases for SLC15A5 Gene

Aliases for SLC15A5 Gene

  • Solute Carrier Family 15, Member 5 2 3

External Ids for SLC15A5 Gene

Summaries for SLC15A5 Gene

GeneCards Summary for SLC15A5 Gene

SLC15A5 (Solute Carrier Family 15, Member 5) is a Protein Coding gene. GO annotations related to this gene include symporter activity. An important paralog of this gene is SLC15A3.

UniProtKB/Swiss-Prot for SLC15A5 Gene

  • Proton oligopeptide cotransporter.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC15A5 Gene

Genomics for SLC15A5 Gene

Genomic Location for SLC15A5 Gene

Start:
16,188,485 bp from pter
End:
16,277,685 bp from pter
Size:
89,201 bases
Orientation:
Minus strand

Genomic View for SLC15A5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC15A5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC15A5 Gene

No data available for Regulatory Elements for SLC15A5 Gene

Proteins for SLC15A5 Gene

  • Protein details for SLC15A5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NIM6-S15A5_HUMAN
    Recommended name:
    Solute carrier family 15 member 5
    Protein Accession:
    A6NIM6
    Secondary Accessions:

    Protein attributes for SLC15A5 Gene

    Size:
    579 amino acids
    Molecular mass:
    65263 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLC15A5 Gene

Proteomics data for SLC15A5 Gene at MOPED

Post-translational modifications for SLC15A5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC15A5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC15A5 Gene

Domains for SLC15A5 Gene

Gene Families for SLC15A5 Gene

HGNC:
  • SLC :Solute carriers

Protein Domains for SLC15A5 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SLC15A5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NIM6

UniProtKB/Swiss-Prot:

S15A5_HUMAN
Family:
  • Belongs to the PTR2/POT transporter (TC 2.A.17) family.:
    • A6NIM6
genes like me logo Genes that share domains with SLC15A5: view

Function for SLC15A5 Gene

Molecular function for SLC15A5 Gene

UniProtKB/Swiss-Prot Function: Proton oligopeptide cotransporter.

Gene Ontology (GO) - Molecular Function for SLC15A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005215 transporter activity --
GO:0015293 symporter activity IEA --
genes like me logo Genes that share ontologies with SLC15A5: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SLC15A5 Gene

Localization for SLC15A5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC15A5 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLC15A5 Gene COMPARTMENTS Subcellular localization image for SLC15A5 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for SLC15A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC15A5: view

Pathways for SLC15A5 Gene

SuperPathways for SLC15A5 Gene

No Data Available

Interacting Proteins for SLC15A5 Gene

Gene Ontology (GO) - Biological Process for SLC15A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport --
GO:0015031 protein transport IEA --
GO:0015833 peptide transport IEA --
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC15A5: view

No data available for Pathways by source for SLC15A5 Gene

Transcripts for SLC15A5 Gene

mRNA/cDNA for SLC15A5 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLC15A5 Gene

Solute carrier family 15, member 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC15A5 Gene

No ASD Table

Relevant External Links for SLC15A5 Gene

GeneLoc Exon Structure for
SLC15A5
ECgene alternative splicing isoforms for
SLC15A5

Expression for SLC15A5 Gene

mRNA expression in normal human tissues for SLC15A5 Gene

mRNA differential expression in normal tissues according to GTEx for SLC15A5 Gene

This gene is overexpressed in Brain - Substantia nigra (5.5), Brain - Amygdala (5.4), and Brain - Anterior cingulate cortex (BA24) (5.1).

SOURCE GeneReport for Unigene cluster for SLC15A5 Gene Hs.692712

genes like me logo Genes that share expressions with SLC15A5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for SLC15A5 Gene

Orthologs for SLC15A5 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SLC15A5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC15A5 35
  • 98.96 (n)
  • 97.93 (a)
SLC15A5 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SLC15A5 35
  • 83.79 (n)
  • 78.2 (a)
SLC15A5 36
  • 77 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLC15A5 35
  • 87.89 (n)
  • 82.01 (a)
SLC15A5 36
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slc15a5 35
  • 75.77 (n)
  • 64.89 (a)
Slc15a5 16
Slc15a5 36
  • 64 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SLC15A5 36
  • 65 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 19 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Slc15a5 35
  • 75.44 (n)
  • 64.49 (a)
chicken
(Gallus gallus)
Aves SLC15A5 35
  • 65.66 (n)
  • 57.17 (a)
SLC15A5 36
  • 56 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SLC15A5 36
  • 56 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101733983 35
  • 62.14 (n)
  • 57.41 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC799543 35
  • 59.54 (n)
  • 54.06 (a)
SLC15A5 36
  • 52 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG9444 36
  • 15 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PTR2 36
  • 16 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 4 (a)
OneToMany
Species with no ortholog for SLC15A5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SLC15A5 Gene

ENSEMBL:
Gene Tree for SLC15A5 (if available)
TreeFam:
Gene Tree for SLC15A5 (if available)

Paralogs for SLC15A5 Gene

Paralogs for SLC15A5 Gene

genes like me logo Genes that share paralogs with SLC15A5: view

Variants for SLC15A5 Gene

Sequence variations from dbSNP and Humsavar for SLC15A5 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs1111660 -- 16,242,284(-) ACTTC(A/G)CCAGG intron-variant
rs1113923 -- 16,252,304(+) agttt(C/T)agaca intron-variant
rs1114813 -- 16,252,159(+) aacta(C/T)cttaa intron-variant
rs1358250 -- 16,249,602(+) AAAAT(A/G)TGTAA intron-variant
rs1358253 -- 16,261,493(-) AAAAG(C/T)CTATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC15A5 Gene

Variant ID Type Subtype PubMed ID
nsv832336 CNV Gain 17160897
dgv480e1 CNV Complex 17122850
nsv428273 CNV Loss 18775914
nsv898826 CNV Loss 21882294
nsv52662 CNV Loss 16902084
nsv512257 CNV Loss 21212237
dgv274n67 CNV Loss 20364138
nsv821614 CNV Deletion 20802225
esv2745595 CNV Deletion 23290073
esv999691 CNV Deletion 20482838
esv2661182 CNV Deletion 23128226
esv1003486 CNV Loss 20482838
esv26884 CNV Gain+Loss 19812545
nsv826267 CNV Loss 20364138
esv1001083 CNV Loss 20482838

Relevant External Links for SLC15A5 Gene

HapMap Linkage Disequilibrium report
SLC15A5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC15A5 Gene

Disorders for SLC15A5 Gene

No disorders were found for SLC15A5 Gene.

No data available for UniProtKB/Swiss-Prot for SLC15A5 Gene

Publications for SLC15A5 Gene

  1. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 3 4
  2. Long evolutionary conservation and considerable tissue specificity of several atypical solute carrier transporters. (PMID: 21044875) Sreedharan S. … Fredriksson R. (Gene 2011) 2 3
  3. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PMID: 22589738) Fox C.S. … Borecki I.B. (PLoS Genet. 2012) 3

Products for SLC15A5 Gene

Sources for SLC15A5 Gene

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