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Set Analyses:

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SLC13A5 Gene

protein-coding GIFtS: 55
GCID: GC17M006588

Solute Carrier Family 13 (Sodium-Dependent Citrate Transporter),...

Search for SLC13A5
at

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
Solute Carrier Family 13 (Sodium-Dependent Citrate Transporter), Member 5¹ ²		Na(+)/Citrate Cotransporter² ³
NACT² ³ ⁵		Solute Carrier Family 13 Member 5²
Sodium-Coupled Citrate Transporter² ³		Solute Carrier Family 13, Member 5²
Sodium-Dependent Citrate Transporter² ³		NaCT³

External Ids:	HGNC: 23089¹	Entrez Gene: 284111²	Ensembl: ENSG00000141485⁷	OMIM: 608305⁵	UniProtKB: Q86YT5³

Export aliases for SLC13A5 gene to outside databases

Previous GC identifers: GC17M006532 GC17M006788 GC17M006529 GC17M006483

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC13A5 Gene:

SLC13A5 is a tricarboxylate plasma transporter with a preference for citrate.(supplied by OMIM, Apr 2004)

GeneCards Summary for SLC13A5 Gene:

SLC13A5 (solute carrier family 13 (sodium-dependent citrate transporter), member 5) is a protein-coding gene. GO annotations related to this gene include succinate transmembrane transporter activity and sodium:dicarboxylate symporter activity. An important paralog of this gene is SLC13A4.

UniProtKB/Swiss-Prot: S13A5_HUMAN, Q86YT5

Function: High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process

is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a

substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for

the synthesis of fatty acids and cholesterol

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000017.11 NT_010718.17 NC_018928.2

Regulatory elements:

Regulatory transcription factor binding sites in the SLC13A5 gene promoter:
AhR GATA-3 GATA-1 Arnt AREB6 E2F-1 E2F AP-2beta AP-2alpha AP-2alphaA
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC13A5 promoter sequence

Search Chromatin IP Primers for SLC13A5

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC13A5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.1 Ensembl cytogenetic band: 17p13.1 HGNC cytogenetic band: 17p13.1

SLC13A5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC13A5 gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17M006588: view genomic region (about GC identifiers)

Start:	6,588,032 bp from pter	End:	6,616,886 bp from pter
Size:	28,855 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: S13A5_HUMAN, Q86YT5 (See protein sequence)

Recommended Name: Solute carrier family 13 member 5

Size: 568 amino acids; 63062 Da

Secondary accessions: B7ZLB4 Q6ZMG1

Alternative splicing: 2 isoforms: Q86YT5-1 Q86YT5-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC13A5: NX_Q86YT5

Explore proteomics data for SLC13A5 at MOPED

Post-translational modifications:

Glycosylation² at Asn562

See SLC13A5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (4 alternative transcripts):

NP_001137310.1 NP_001271438.1 NP_001271439.1 NP_808218.1

ENSEMBL proteins:

ENSP00000406220 ENSP00000293800 ENSP00000370464 ENSP00000459372 ENSP00000460037

ENSP00000466899 ENSP00000461495 ENSP00000461622 ENSP00000461554 ENSP00000460903

Reactome Protein details: Q86YT5

SLC13A5 Human Recombinant Protein Products:

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	Novus Biologicals SLC13A5 Protein
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SLC13A5 Assay Products:

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	Cloud-Clone Corp. ELISAs for SLC13A5 Cloud-Clone Corp. CLIAs for SLC13A5

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:

SLC: Solute carriers

IUPHAR Guide to PHARMACOLOGY protein family classification: Na⁺/citrate cotransporter

SLC13 family of sodium-dependent sulphate/carboxylate transporters

1 InterPro protein domain:

IPR001898 Na/sul_symport

Graphical View of Domain Structure for InterPro Entry Q86YT5

ProtoNet protein and cluster: Q86YT5

1 Blocks protein domain: IPB001898 Sodium/sulphate symporter

UniProtKB/Swiss-Prot: S13A5_HUMAN, Q86YT5

Similarity: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily

SLC13A5 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

UniProtKB/Swiss-Prot Summary: S13A5_HUMAN, Q86YT5

Function: High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process

is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a

substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for

the synthesis of fatty acids and cholesterol

Gene Ontology (GO): Selected molecular function terms (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005215	transporter activity	--	--
GO:0005343	organic acid:sodium symporter activity	--	--
GO:0015137	citrate transmembrane transporter activity	IEA	--
GO:0015141	succinate transmembrane transporter activity	IEA	--
GO:0015142	tricarboxylic acid transmembrane transporter activity	--	--

SLC13A5 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for SLC13A5:

Proliferating cells

7 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Slc13a5):

adipose tissue	behavior/neurological	growth/size/body	homeostasis/metabolism	liver/biliary system
muscle	no phenotypic analysis

SLC13A5 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC13A5

inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SLC13A5

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC13A5

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLC13A5

miRNA Products:		Block miRNA regulation of human, mouse, rat SLC13A5 using miScript Target Protectors
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		hsa-miR-4303 hsa-miR-9 hsa-miR-122 hsa-miR-1976
		SwitchGear 3'UTR luciferase reporter plasmid: SLC13A5 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for SLC13A5
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Gene Editing
Products:

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC13A5

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

S13A5_HUMAN, Q86YT5: Membrane; Multi-pass membrane protein

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
plasma membrane	4

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Gene Ontology (GO): 4 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	TAS	--
GO:0016020	membrane	--	--
GO:0016021	integral component of membrane	IEA	--
GO:0016323	basolateral plasma membrane	IEA	--

SLC13A5 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for SLC13A5 About

See pathways by source

SuperPath

Contained pathways About

Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds

	SLC-mediated transmembrane transport	0.47			Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	0.38
	Transmembrane transport of small molecules	0.47			Sodium-coupled sulphate, di- and tri-carboxylate transporters	0.00

Pathways by source See SuperPaths
Show all pathways

1 Reactome Pathway for SLC13A5

Sodium-coupled sulphate, di- and tri-carboxylate transporters

SLC13A5 for pathways About GeneDecksing

Custom Pathway & Disease-focused RT² Profiler PCR Arrays for SLC13A5
Interactions:

Search GeneGlobe Interaction Network for SLC13A5

STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

Selected Interacting proteins for SLC13A5 (ENSP00000293800⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 9)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SLC20A1	ENSP00000272542⁴	STRING: ENSP00000272542
SLC20A2	ENSP00000340465⁴	STRING: ENSP00000340465
SLC13A3	ENSP00000279027⁴	STRING: ENSP00000279027
AIMP1	ENSP00000378191⁴	STRING: ENSP00000378191
CDK14	ENSP00000265741⁴	STRING: ENSP00000265741

About this table

Gene Ontology (GO): Selected biological process terms (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006814	sodium ion transport	--	--
GO:0006842	tricarboxylic acid transport	--	--
GO:0015744	succinate transport	--	--
GO:0015746	citrate transport	--	--
GO:0035674	tricarboxylic acid transmembrane transport	--	--

SLC13A5 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for SLC13A5 (S13A5)

1 HMDB Compound for SLC13A5 About this table

Compound	Synonyms	CAS #	PubMed Ids
Sodium	Sodium (see all 2)	7440-23-5	--

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for SLC13A5 gene (4 alternative transcripts):

NM_001143838.2 NM_001284509.1 NM_001284510.1 NM_177550.4

Unigene Cluster for SLC13A5:

Solute carrier family 13 (sodium-dependent citrate transporter), member 5

Hs.399496 [show with all ESTs]

Unigene Representative Sequence: BX647354

12 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000433363(uc002gdj.3 uc010vtf.2 uc010clq.3 uc002gdk.3)

ENST00000574580 ENST00000293800 ENST00000381074 ENST00000573648 ENST00000570687

ENST00000572727 ENST00000574824(uc002gdl.1) ENST00000572094 ENST00000572352

ENST00000576323 ENST00000575230

miRNA Products:		Block miRNA regulation of human, mouse, rat SLC13A5 using miScript Target Protectors
		4 qRT-PCR Assays for microRNAs that regulate SLC13A5:
		hsa-miR-4303 hsa-miR-9 hsa-miR-122 hsa-miR-1976
		SwitchGear 3'UTR luciferase reporter plasmid: SLC13A5 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for SLC13A5
		Predesigned siRNA for gene silencing in human, mouse, rat SLC13A5

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		GenScript: all cDNA clones in your preferred vector (see all 2): SLC13A5 (NM_177550)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC13A5
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		QuantiFast Probe-based Assays in human, mouse, rat SLC13A5

Additional mRNA sequence:

AJ489980.1 AK124317.1 AK127797.1 AK131206.1 AK172779.1 AK172785.1 AK297612.1 AY151833.1

BC104795.1 BC112151.1 BC143689.1 BX647354.1 CR749584.1

8 DOTS entries:

DT.215029 DT.40296888 DT.99942300 DT.100738015 DT.100000016 DT.102824130 DT.100648227 DT.92416972

Selected AceView cDNA sequences (see all 59):

Z45042 BQ647893 Z40774 AK127797 BX445866 BX463054 BQ654357 CK300817

AW297485 AW297488 NM_177550 U92029 BX431856 BQ189694 BX951550 BQ654393

AK131206 AY151833 BG616615 AW592531 AI797218 R93718 CB163988 AK172785

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for SLC13A5 (see all 8) About this scheme

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	^	3a	·	3b	^	4a	·	4b	·	4c	^	5	^	6	^	7	^	8a	·	8b	^	9a	·	9b	^	10	^	11	^	12	^	13	^	14
SP1:											-				-		-												-										-
SP2:											-				-														-										-
SP3:											-				-
SP4:							-		-		-				-														-
SP5:																													-

ECgene alternative splicing isoforms for SLC13A5

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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SLC13A5 expression in normal human tissues (normalized intensities) SLC13A5 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: AGAGACAAGC

About this image

SLC13A5 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 2) fully expand


Bone (Muscoskeletal System) fully expand to see all 5 entries
Zeugopod Growth Plate
Chondrocyte-like cells

Cartilage (Muscoskeletal System) fully expand to see all 4 entries
Chondrocyte-like cells

SLC13A5 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

SLC13A5 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.399496

UniProtKB/Swiss-Prot: S13A5_HUMAN, Q86YT5

Tissue specificity: Expressed most predominantly in the liver, with moderate expression detectable in the brain

and testis

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC13A5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for SLC13A5 gene from Selected species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Slc13a5^{1 , 5}	solute carrier family 13 (sodium-dependent citrate more^{1, 5}	80.11(n)¹ 75(a)¹		11 (43.95 cM)⁵ 237831¹ NM_001004148.4¹ NP_001004148.1¹ 72241994⁵
chicken (Gallus gallus)	Aves	SLC13A5¹	solute carrier family 13 (sodium-dependent citrate more	65.04(n) 65.82(a)		417678 XM_004946805.1 XP_004946862.1
lizard (Anolis carolinensis)	Reptilia	SLC13A5⁶	solute carrier family 13 (sodium-dependent citrate...	67(a)	1 ↔ 1	AAWZ02039898(2012-7443)
tropical clawed frog (Xenopus tropicalis)	Amphibia	slc13a5¹	solute carrier family 13 (sodium-dependent citrate more	65.13(n) 65.72(a)		100490590 XM_002933513.2 XP_002933559.1
zebrafish (Danio rerio)	Actinopterygii	slc13a5a¹	info solute carrier family 13 (sodium-dependent citrate more	65.25(n) 63.23(a)		503788 NM_001142566.1 NP_001136038.1
fruit fly (Drosophila melanogaster)	Insecta	Indy⁶	I'm not dead yet	34(a)	many ↔ many	3L(18821732-18839367)
worm (Caenorhabditis elegans)	Secernentea	nac-3⁶ nac-1⁶	Protein NAC-1 (nac-1) mRNA, complete cds	39(a) 38(a)	many ↔ many many ↔ many	III(10152795-10157920) WBGene00003519 X(14895145-14898441) WBGene00003517

ENSEMBL Gene Tree for SLC13A5 (if available)
TreeFam Gene Tree for SLC13A5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for SLC13A5 gene

SLC13A4² SLC13A1² SLC13A2² SLC13A3²

5 SIMAP similar genes for SLC13A5 using alignment to 9 protein entries: S13A5_HUMAN (see all proteins):

DKFZp686E17257 SLC13A2 SLC13A3 SLC13A1 SLC13A4

SLC13A5 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs185231878^1,2		--	6587574(+)	`CCACCC/GTGTCT`	2	--	ds500¹		0	--	--	--	--
rs60127825^1,2	C,F	--	6587576(+)	`ACCCTG/CTCTCA`	2	--	ds500¹		2		WA	120
rs190877400^1,2		--	6587631(+)	`GGACTC/TATGTT`	2	--	ds500¹		0	--	--	--	--
rs116772780^1,2	C,F	--	6587638(+)	`TGTTTG/TGAGAT`	2	--	ds500¹		1		WA	118
rs57791721^1,2	C,F	--	6587649(+)	`CTTCCC/GTTGGC`	2	--	ds500¹		2		WA	120
rs183388416^1,2	C	--	6587657(+)	`GGCATA/GGACTT`	2	--	ds500¹		0	--	--	--	--
rs116540819^1,2	F	--	6587660(+)	`ATGGAC/TTTGCT`	2	--	ds500¹		1		WA	118
rs145117381^1,2		--	6587793(+)	`TGTGAA/CTTTGG`	2	--	ds500¹		0	--	--	--	--
rs147145493^1,2		--	6587861(+)	`TAACAC/GCTTCC`	2	--	ds500¹		0	--	--	--	--
rs201004816^1,2	C	--	6587875(+)	`CTCAC-/GGGTTG`	2	--	ds500¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SLC13A5 (6588032 - 6616886 bp)

Structural Variations
Database of Genomic Variants (DGV) 2 variations for SLC13A5: About this table

Variant ID	Type	Subtype	PubMed ID
nsv907631	CNV	Loss	21882294
nsv907630	CNV	Gain	21882294

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 608305 OMIM disorders: --

SLC13A5 for disorders About GeneDecksing

Genetic Association Database (GAD): SLC13A5
Human Genome Epidemiology (HuGE) Navigator: SLC13A5 (1 document)

Export disorders for SLC13A5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for SLC13A5 gene, integrated from 10 sources (see all 14):
(articles sorted by number of sources associating them with SLC13A5)

Utopia: connect your pdf to the dynamic
world of online information

Human Na+ -coupled citrate transporter: primary structure, genomic organization, and transport function. (PubMed id 12445824)^{1, 2, 3, 9} Inoue K.... Ganapathy V. (Biochem. Biophys. Res. Commun. 2002)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)^{1, 4} Rose J.E....Uhl G.R. (Mol. Med. 2010)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
Human sodium-coupled citrate transporter, the orthologue of Drosophila Indy, as a novel target for lithium action. (PubMed id 12826022)^{1, 9} Inoue K....Ganapathy V. (Biochem. J. 2003)
The genetic architecture of economic and political preferences. (PubMed id 22566634)¹ Benjamin D.J....Visscher P.M. (Proc. Natl. Acad. Sci. U.S.A. 2012)
Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)² Chen R.... Zou H. (J. Proteome Res. 2009)
Expression and functional features of NaCT, a sodium-coupled citrate transporter, in human and rat livers and cell lines. (PubMed id 16973915)¹ Gopal E....Ganapathy V. (Am. J. Physiol. Gastrointest. Liver Physiol. 2007)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (Genome Res. 2006)
Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters. (PubMed id 16211368)¹ Pajor A.M. (Pflugers Arch. 2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 284111	HGNC: 23089	AceView: SLC13A5	Ensembl:ENSG00000141485	euGenes: HUgn284111
ECgene: SLC13A5	H-InvDB: SLC13A5

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for SLC13A5	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SLC13A5 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for SLC13A5 gene:
Search GeneIP for patents involving SLC13A5

GeneCards and IP:
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