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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC13A4 Gene

protein-coding   GIFtS: 53
GCID: GC07M135365

solute carrier family 13 (sodium/sulfate symporters), member...

(Previous names: solute carrier family 13 (sodium/sulphate symporters),...)
 Explore 2 diseases affiliated with
SLC13A4 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SLC13A4    

Aliases
for SLC13A4 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Solute Carrier Family 13 (Sodium/Sulfate Symporters), Member 41 2     NaS23
SUT11 2 3 5     Solute Carrier Family 13 Member 42
SUT-11 2     Sulphate Transporter 12
Solute Carrier Family 13 (Sodium/Sulphate Symporters), Member 41 2     NaS23
Na(+)/Sulfate Cotransporter SUT-12 3     

External Ids:    HGNC: 158271   Entrez Gene: 262662   Ensembl: ENSG000001647077   OMIM: 6043095   UniProtKB: Q9UKG43   

Export aliases for SLC13A4 gene to outside databases

Previous GC identifers: GC07M133708 GC07M134768 GC07M134782 GC07M134823 GC07M135016 GC07M129668


Summaries
for SLC13A4 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: S13A4_HUMAN, Q9UKG4
Function: Sodium/sulfate cotransporter that mediates sulfate reabsorption in the high endothelial venules (HEV)




Genomic Views
for SLC13A4 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007933.15  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC13A4 gene promoter:
         GR   Sox5   POU2F1   CBF-A   CBF-B   POU2F1a   CP1A   GR-alpha   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SLC13A4 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC13A4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC13A4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q33   Ensembl cytogenetic band:  7q33   HGNC cytogenetic band: 7q33

SLC13A4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC13A4 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M135365:  view genomic region     (about GC identifiers)

Start:
 135,365,985 bp from pter      End:
 135,412,952 bp from pter
Size:
 46,968 bases      Orientation:
 minus strand

1 alternative location:
Chr7-,CRA_TCAG 134,710,411-134,757,363     

Proteins
for SLC13A4 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: S13A4_HUMAN, Q9UKG4 (See protein sequence)
Recommended Name: Solute carrier family 13 member 4  
Size: 626 amino acids; 69358 Da
Subcellular location: Membrane; Multi-pass membrane protein
Miscellaneous: Transport is inhibited by thiosulfate, phosphate, molybdate, selenate and tungstate. Not inhibited by
oxalate, citrate, succinate, phenol red or 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS)
Secondary accessions: A4D1Q4 Q8N631

Explore the universe of human proteins at neXtProt for SLC13A4: NX_Q9UKG4

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UKG4

    • SLC13A4 Protein expression data from MOPED and PaxDb:    About this image 
    SLC13A4 Protein Expression
    REFSEQ proteins: NP_036582.2  
    ENSEMBL proteins: 
     ENSP00000297282  
    Reactome Protein details: Q9UKG4
    Human Recombinant Protein Products for SLC13A4: 
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    Novus Biologicals SLC13A4 Protein
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SLC13A4

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane TAS10535998

    SLC13A4 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for SLC13A4

    Protein Domains /
    Families
    for SLC13A4 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC13A4 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001898 Na/sul_symport

    Graphical View of Domain Structure for InterPro Entry Q9UKG4

    ProtoNet protein and cluster: Q9UKG4

    1 Blocks protein family: IPB001898 Sodium/sulphate symporter

    UniProtKB/Swiss-Prot: S13A4_HUMAN, Q9UKG4
    Similarity: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily


    Function
    for SLC13A4 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S13A4_HUMAN, Q9UKG4
    Function: Sodium/sulfate cotransporter that mediates sulfate reabsorption in the high endothelial venules (HEV)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015382sodium:sulfate symporter activity TAS10535998
         
    SLC13A4 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SLC13A4:
     Increased gamma-H2AX phosphory 

         1 MGI phenotypic allele for Slc13a4 (no phenotypes)

    SLC13A4 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SLC13A4 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC13A4
    1 QIAGEN miScript miRNA Assays for microRNA that regulate SLC13A4:
    hsa-miR-526b
    SwitchGear 3'UTR luciferase reporter plasmid: SLC13A4 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC13A4 (see all 7)
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    Gene Editing
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    Clone
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    Cell Line
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    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC13A4


    Pathways & Interactions
    for SLC13A4 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1SLC-mediated transmembrane transport
    		SLC-mediated transmembrane transport1.00
    		Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    		Transmembrane transport of small molecules0.50
    2Bile salt and organic anion SLC transporters
    		Bile salt and organic anion SLC transporters1.00
    		Sodium-coupled sulphate, di- and tri-carboxylate transporters0.42

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5        Reactome Pathways for SLC13A4
        Sodium-coupled sulphate, di- and tri-carboxylate transporters
    Bile salt and organic anion SLC transporters
    SLC-mediated transmembrane transport
    Transmembrane transport of small molecules
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds



    SLC13A4 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SLC13A4

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008272sulfate transport TAS10535998
    GO:0055085transmembrane transport TAS--

    SLC13A4 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC13A4 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC13A4 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC13A4

    3 HMDB Compounds for SLC13A4    About this table
    CompoundSynonyms CAS #PubMed Ids
    Phenolacide carbolique (see all 51)108-95-2--
    SodiumSodium (see all 2)7440-23-5--
    SulfateSulfate (ion 2-) (see all 9)14808-79-8--
    1 Novoseek chemical compound relationship for SLC13A4 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sulfate 61.7 10 10535998 (6), 11161786 (1)

    Search CenterWatch for drugs/clinical trials and news about SLC13A4 / S13A4 

    Transcripts
    for SLC13A4 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SLC13A4 gene: 
    NM_012450.2  

    Unigene Cluster for SLC13A4:

    Solute carrier family 13 (sodium/sulfate symporters), member 4
    Hs.490241  [show with all ESTs]
    Unigene Representative Sequence: AB208809
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000491630 ENST00000354042(uc003vta.3) ENST00000471405(uc003vtb.3)
    ENST00000466505 ENST00000480376 ENST00000478310

    miRNA
    Products:             		 OriGene 3'-UTR Clone: SLC13A4
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC13A4
    1 QIAGEN miScript miRNA Assays for microRNA that regulate SLC13A4:
    hsa-miR-526b
    SwitchGear 3'UTR luciferase reporter plasmid: SLC13A4 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC13A4 (see all 7)
    OriGene shRNA RFP: SLC13A4
    OriGene siRNA: SLC13A4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC13A4
    Sirion Biotech Custom design and validation of potent shRNA sequences against SLC13A4 
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC13A4
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    GenScript: all cDNA clones in your preferred vector: SLC13A4 (NM_012450)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC13A4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC13A4 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC13A4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC13A4

    Additional cDNA sequence: 

    AB208809.1 AF169301.1 AK091838.1 AK313072.1 BC030689.2 

    12 DOTS entries:

    DT.410887  DT.100723621  DT.91845303  DT.100760255  DT.121109623  DT.95187826  DT.99933244  DT.100708450 
    DT.121109646  DT.407412  DT.92012463  DT.108523 

    24/62 AceView cDNA sequences (see all 62):

    CD103602 Z43427 BQ186817 CR597198 CA389842 BX377955 BC030689 BX334792 
    CR597145 NM_012450 BX380281 BX399463 BX382559 BG699706 BG699506 BI462586 
    BX345171 BX360002 BX377954 CD512539 AI372657 BI545080 BF111995 AL544581 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SLC13A4    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17
    SP1:                                                                                                                                    
    SP2:                                                                                                                                    
    SP3:              -     -     -                                                                                                         
    SP4:              -     -                                                                                                               


    ECgene alternative splicing isoforms for SLC13A4

    Expression
    for SLC13A4 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC13A4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTTCGCTGTT
    SLC13A4 Expression
    About this image

    SLC13A4 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainBlood Brain BarrierAdult Endothelial CellsBlood Brain Barrier, Endothelium
    BrainChoroid PlexusMature Choroid Plexus CellsChoroid Plexus
    BoneZeugopod Growth PlateBone
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    Syncytiotrophoblast-like cells (Generation of syncyt...)
    Cardiomyocyte-like cells (Spontaneous differen...)

    See SLC13A4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC13A4

    SOURCE GeneReport for Unigene cluster: Hs.490241

    UniProtKB/Swiss-Prot: S13A4_HUMAN, Q9UKG4
    Tissue specificity: Highly expressed in placenta and testis with intermediate levels in brain and lower levels in
    heart, thymus and liver

        SABiosciences Custom PCR Arrays for SLC13A4
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC13A4

    Orthologs
    for SLC13A4 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for SLC13A4 gene from 9/27 species (see all 27)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SLC13A41 solute carrier family 13 (sodium/sulfate symporters), member 4 less 75.91(n)
    79.81(a)    		   418127  XM_416360.2  XP_416360.2 
    lizard
    (Anolis carolinensis)    		 Reptilia SLC13A46
    		 --
    		 75(a)
    		 1 ↔ 1
    		 GL343602.1(324599-361051)
    African clawed frog
    (Xenopus laevis)    		 Amphibia MGC535212 similar to solute carrier family 13, member 1 74.63(n)    BC047132.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc:1624951 zgc:162495 68.65(n)
    70.36(a)    		   100038771  NM_001089551.1  NP_001083020.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Indy6
    Indy-26
    (see all 4)    		 I'm not dead yet 2
    (see all 4)    		 31(a)
    28(a)
    (see all 4)    		 many ↔ many
    many ↔ many
    (see all 4)    		 3L(18821732-18839367)
    3R(15868479-15874438)
    worm
    (Caenorhabditis elegans)    		 Secernentea F31F6.63
    nac-21    		 Na+/sulphate co-transporter like3
    Protein NAC-21    		 33(a)3
    44.96(n)1
    34.87(a)1    		   X(14930379-14933500)3
    1878981  NM_066599.41  NP_499000.21 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons ATSDAT6
    		 tonoplast dicarboxylate transporter
    		 28(a)
    		 1 → many
    		 5(19287369-19290465)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    		 citrate transporter, putative, expressed
    		 27(a)
    25(a)
    		 many ↔ many
    many ↔ many
    		 9(18714286-18717864)
    8(24880211-24883636)
    E. coli
    (Escherichia coli)    		 Gamma proteobacteria yfbS6
    		 predicted transporter
    		 12(a)
    		 possible ortholog
    		 Chromosome(2407542-2409374)


    ENSEMBL Gene Tree for SLC13A4 (if available)
    TreeFam Gene Tree for SLC13A4 (if available) 

    Paralogs
    for SLC13A4 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC13A4 gene
    SLC13A52  SLC13A12  SLC13A22  SLC13A32  
    5 SIMAP similar genes for SLC13A4 using alignment to 1 protein entry:     S13A4_HUMAN:
    DKFZp686E17257    SLC13A1    SLC13A3    SLC13A2    SLC13A5

    SLC13A4 for paralogs           About GeneDecksing



    Genomic Variants
    for SLC13A4 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/986 NCBI SNPs in SLC13A4 are shown (see all 986)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 7 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1823655861,2
    		--135365569(+) GAAAAC/GCAGCT 1 -- int10--------
    rs1505449271,2
    		--135365628(+) CAGTAA/GAATCG 1 -- int10--------
    rs284366981,2
    		C--135365736(+) AAAAAG/AAGAGA 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1874163671,2
    		--135365771(+) GTTTCA/GAGGTC 1 -- int10--------
    rs1917530761,2
    		--135365790(+) GTTTCC/TCACAA 1 -- int10--------
    rs768564481,2
    		C--135365792(+) TTCCCA/GCAAAA 1 -- int10--------
    rs1472440721,2
    		--135365792(+) CCCAC-/AAAAAA 1 -- int10--------
    rs1394514121,2
    		--135365847(+) ATCTTC/TCTACT 1 -- int10--------
    rs132461201,2
    		C--135365886(+) ACCTAG/TTGAGT 1 -- int11Minor allele frequency- T:0.00NA 2
    rs731607081,2
    		C--135365946(+) GTCTTC/AAGAAT 1 -- int14Minor allele frequency- A:0.09NA WA EA 360

    HapMap Linkage Disequilibrium report for SLC13A4 (135365985 - 135412952 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SLC13A4: --

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for SLC13A4 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC13A4 for disorders           About GeneDecksing

    OMIM gene information: 604309    OMIM disorders: --

    2 diseases for SLC13A4:    About MalaCards
    diastrophic dysplasia    pharyngitis

    Human Genome Epidemiology (HuGE) Navigator: SLC13A4 (1 document)

    Export disorders for SLC13A4 gene to outside databases

    Publications
    for SLC13A4 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC13A4 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with SLC13A4)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and functional analysis of SUT-1, a sulfate transporter from human high endothelial venules. (PubMed id 10535998)1, 2, 3, 9 Girard J.-P.... Amalric F. (1999)
    2. Functional characterization and genomic organization of the human Na(+)-sulfate cotransporter hNaS2 gene (SLC13A4). (PubMed id 15607730)1, 2, 9 Markovich D.... Dawson P.A. (2005)
    3. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    5. Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters. (PubMed id 16211368)1 Pajor A.M. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Fusion to GFP blocks intercellular trafficking of the sucrose transporter SUT1 leading to accumulation in companion cells. (PubMed id 14667250)9 Lalonde S....Frommer W.B. (2003)
    10. The human renal sodium sulfate cotransporter (SLC13A1; hNaSi-1) cDNA and gene: organization, chromosomal localization, and functional characterization. (PubMed id 11161786)9 Lee A.... Markovich D. (2000)

    External Searches for SLC13A4 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing SLC13A4 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26266 HGNC: 15827 AceView: SLC13A4 Ensembl:ENSG00000164707 euGenes: HUgn26266
    ECgene: SLC13A4 H-InvDB: SLC13A4

    Other Databases showing SLC13A4 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SLC13A4 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC13A4 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC13A4 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC13A4 gene:
    Search GeneIP for patents involving SLC13A4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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