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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC13A4 Gene

protein-coding   GIFtS: 55
GCID: GC07M135365

Solute Carrier Family 13 (Sodium/Sulfate Symporter), Member...

(Previous names: solute carrier family 13 (sodium/sulphate symporters), member...)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 13 (Sodium/Sulfate Symporter), Member 41 2     SUT-12
SUT12 3 5     naS22
Solute Carrier Family 13 (Sodium/Sulphate Symporters), Member 41 2     Solute Carrier Family 13 (Sodium/Sulfate Symporters), Member 42
Sulphate Transporter 11 2     Solute Carrier Family 13 Member 42
Na(+)/Sulfate Cotransporter SUT-12 3     NaS23

External Ids:    HGNC: 158271   Entrez Gene: 262662   Ensembl: ENSG000001647077   OMIM: 6043095   UniProtKB: Q9UKG43   

Export aliases for SLC13A4 gene to outside databases

Previous GC identifers: GC07M133708 GC07M134768 GC07M134782 GC07M134823 GC07M135016 GC07M129668


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SLC13A4 Gene: 
SLC13A4 (solute carrier family 13 (sodium/sulfate symporter), member 4) is a protein-coding gene. Diseases associated with SLC13A4 include diastrophic dysplasia, and endotheliitis, and among its related super-pathways are Transmembrane transport of small molecules and Sodium-coupled sulphate, di- and tri-carboxylate transporters. GO annotations related to this gene include sodium:sulfate symporter activity. An important paralog of this gene is SLC13A5.

UniProtKB/Swiss-Prot: S13A4_HUMAN, Q9UKG4
Function: Sodium/sulfate cotransporter that mediates sulfate reabsorption in the high endothelial venules (HEV)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007933.15  NC_018918.2  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC13A4 gene promoter:
         GR   Sox5   POU2F1   CBF-A   CBF-B   POU2F1a   CP1A   GR-alpha   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SLC13A4 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC13A4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC13A4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q33   Ensembl cytogenetic band:  7q33   HGNC cytogenetic band: 7q33

SLC13A4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC13A4 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M135365:  view genomic region     (about GC identifiers)

Start:
135,365,985 bp from pter      End:
135,412,952 bp from pter
Size:
46,968 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 134,710,411-134,757,363     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: S13A4_HUMAN, Q9UKG4 (See protein sequence)
Recommended Name: Solute carrier family 13 member 4  
Size: 626 amino acids; 69358 Da
Subcellular location: Membrane; Multi-pass membrane protein
Miscellaneous: Transport is inhibited by thiosulfate, phosphate, molybdate, selenate and tungstate. Not inhibited
by oxalate, citrate, succinate, phenol red or 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS)
Secondary accessions: A4D1Q4 Q8N631

Explore the universe of human proteins at neXtProt for SLC13A4: NX_Q9UKG4

Explore proteomics data for SLC13A4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UKG4

  • SLC13A4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC13A4 Protein Expression
    REFSEQ proteins: NP_036582.2  
    ENSEMBL proteins: 
     ENSP00000297282  
    Reactome Protein details: Q9UKG4
    Human Recombinant Protein Products for SLC13A4: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SLC13A4 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane TAS10535998
    GO:0016020membrane ----
    GO:0016021integral to membrane ----

    SLC13A4 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Na+/sulfate cotransporter 
    SLC13 family of sodium-dependent sulphate/carboxylate transporters

    1 InterPro protein domain:
     IPR001898 Na/sul_symport

    Graphical View of Domain Structure for InterPro Entry Q9UKG4

    ProtoNet protein and cluster: Q9UKG4

    1 Blocks protein domain: IPB001898 Sodium/sulphate symporter

    UniProtKB/Swiss-Prot: S13A4_HUMAN, Q9UKG4
    Similarity: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily


    SLC13A4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S13A4_HUMAN, Q9UKG4
    Function: Sodium/sulfate cotransporter that mediates sulfate reabsorption in the high endothelial venules (HEV)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity ----
    GO:0015382sodium:sulfate symporter activity TAS10535998
         
    SLC13A4 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SLC13A4:
     Increased gamma-H2AX phosphory 

         1 MGI phenotypic allele for Slc13a4 (no phenotypes)

    SLC13A4 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC13A4 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC13A4 
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    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate SLC13A4:
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    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC13A4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SLC13A4 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1SLC-mediated transmembrane transport
    SLC-mediated transmembrane transport0.50
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    Transmembrane transport of small molecules0.50
    2Bile salt and organic anion SLC transporters
    Bile salt and organic anion SLC transporters0.42
    Sodium-coupled sulphate, di- and tri-carboxylate transporters0.42

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5        Reactome Pathways for SLC13A4
        Sodium-coupled sulphate, di- and tri-carboxylate transporters
    Bile salt and organic anion SLC transporters
    SLC-mediated transmembrane transport
    Transmembrane transport of small molecules
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds



    SLC13A4 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SLC13A4

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006814sodium ion transport ----
    GO:0008272sulfate transport TAS10535998
    GO:0055085transmembrane transport TAS--

    SLC13A4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC13A4 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC13A4 (S13A4)

    3 HMDB Compounds for SLC13A4    About this table
    CompoundSynonyms CAS #PubMed Ids
    Phenolacide carbolique (see all 51)108-95-2--
    SodiumSodium (see all 2)7440-23-5--
    SulfateSulfate (ion 2-) (see all 9)14808-79-8--

    1 Novoseek inferred chemical compound relationship for SLC13A4 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sulfate 61.7 10 10535998 (6), 11161786 (1)

    Search CenterWatch for drugs/clinical trials and news about SLC13A4 / S13A4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC13A4 gene: 
    NM_012450.2  

    Unigene Cluster for SLC13A4:

    Solute carrier family 13 (sodium/sulfate symporters), member 4
    Hs.490241  [show with all ESTs]
    Unigene Representative Sequence: AB208809
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000491630 ENST00000354042(uc003vta.3) ENST00000471405(uc003vtb.3)
    ENST00000480376 ENST00000478310
    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate SLC13A4:
    hsa-miR-526b
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    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC13A4
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    Additional mRNA sequence: 

    AB208809.1 AF169301.1 AK091838.1 AK313072.1 BC030689.2 

    12 DOTS entries:

    DT.410887  DT.100723621  DT.91845303  DT.100760255  DT.121109623  DT.95187826  DT.99933244  DT.100708450 
    DT.121109646  DT.407412  DT.92012463  DT.108523 

    24/62 AceView cDNA sequences (see all 62):

    CD103602 BQ186817 BX334792 BX380281 CA389842 Z43427 NM_012450 BC030689 
    CR597198 CR597145 BX377955 BX399463 BG219860 BG704502 BX396335 BG701217 
    AF169301 BF111995 CB999093 BG699706 BX356289 BX377498 AI372657 BX382559 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SLC13A4    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17
    SP1:                                                                                                                                    
    SP2:                                                                                                                                    
    SP3:              -     -     -                                                                                                         
    SP4:              -     -                                                                                                               


    ECgene alternative splicing isoforms for SLC13A4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC13A4 expression in normal human tissues (normalized intensities)      SLC13A4 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTCGCTGTT
    SLC13A4 Expression
    About this image


    SLC13A4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/9 selected tissues (see all 9) fully expand
     
     Choroid Plexus (Nervous System)    fully expand to see all 3 entries
             Mature Choroid Plexus Cells Choroid Plexus
             Human Choroid Plexus Fibroblasts (HCPF)   
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Zeugopod Growth Plate
             BONE MARROW   
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Adult Endothelial Cells Blood Brain Barrier
     
     Placenta (Extraembryonic Tissues)
             placenta   
     
     Blood Brain Barrier (Nervous System)
             Adult Endothelial Cells Blood Brain Barrier

    See SLC13A4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC13A4

    SOURCE GeneReport for Unigene cluster: Hs.490241

    UniProtKB/Swiss-Prot: S13A4_HUMAN, Q9UKG4
    Tissue specificity: Highly expressed in placenta and testis with intermediate levels in brain and lower levels in
    heart, thymus and liver

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC13A4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC13A4 gene from 8/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc13a41 , 5 solute carrier family 13 (sodium/sulfate symporters), more1, 5 86.44(n)1
    89.39(a)1
      6 (15.26 cM)5
    2437551  NM_172892.31  NP_766480.11 
     352679575 
    chicken
    (Gallus gallus)
    Aves SLC13A41 solute carrier family 13 (sodium/sulfate symporters), more 75.91(n)
    79.81(a)
      418127  XM_416360.2  XP_416360.2 
    lizard
    (Anolis carolinensis)
    Reptilia SLC13A46
    Uncharacterized protein
    65(a)
    1 ↔ 1
    GL343602.1(323946-363641)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC535212 similar to solute carrier family 13, member 1 74.63(n)    BC047132.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1624951 zgc:162495 68.65(n)
    70.36(a)
      100038771  NM_001089551.1  NP_001083020.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Indy6
    CG339346
    (see all 4)
    --
    30(a)
    28(a)
    (see all 4)
    many ↔ many
    many ↔ many
    (see all 4)
    3L(18821732-18839367)
    3R(15868479-15874438)
    worm
    (Caenorhabditis elegans)
    Secernentea F31F6.63
    nac-21
    Na+/sulphate co-transporter like3
    Protein NAC-21
    33(a)3
    44.96(n)1
    34.87(a)1
      X(14930379-14933500)3
    1878981  NM_066599.41  NP_499000.21 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PHO916
    PHO906
    (see all 3)
    Low-affinity phosphate transporter of the vacuolar...
    Low-affinity phosphate transporter; deletion of ph...
    (see all 3)
    11(a)
    11(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    XIV(649028-651712)
    X(60844-63489)


    ENSEMBL Gene Tree for SLC13A4 (if available)
    TreeFam Gene Tree for SLC13A4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC13A4 gene
    SLC13A52  SLC13A12  SLC13A22  SLC13A32  
    5 SIMAP similar genes for SLC13A4 using alignment to 1 protein entry:     S13A4_HUMAN:
    DKFZp686E17257    SLC13A1    SLC13A2    SLC13A3    SLC13A5

    SLC13A4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1118 SNPs in SLC13A4 are shown (see all 1118)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1823655861,2
    --135365569(+) GAAAAC/GCAGCT 1 -- int10--------
    rs1505449271,2
    --135365628(+) CAGTAA/GAATCG 1 -- int10--------
    rs284366981,2
    C--135365736(+) AAAAAG/AAGAGA 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1874163671,2
    --135365771(+) GTTTCA/GAGGTC 1 -- int10--------
    rs1917530761,2
    --135365790(+) GTTTCC/TCACAA 1 -- int10--------
    rs768564481,2
    C--135365792(+) TTCCCA/GCAAAA 1 -- int10--------
    rs1472440721,2
    C--135365793(+) CCCAC-/AAAAAA 1 -- int10--------
    rs1394514121,2
    --135365847(+) ATCTTC/TCTACT 1 -- int10--------
    rs132461201,2
    C--135365886(+) ACCTAG/TTGAGT 1 -- int11Minor allele frequency- T:0.00NA 2
    rs731607081,2
    C--135365946(+) GTCTTC/AAGAAT 1 -- int14Minor allele frequency- A:0.09NA WA EA 360

    HapMap Linkage Disequilibrium report for SLC13A4 (135365985 - 135412952 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for SLC13A4: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC13A4
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC13A4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604309    OMIM disorders: --

    2 diseases for SLC13A4:    About MalaCards
    diastrophic dysplasia    endotheliitis


    SLC13A4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC13A4
    Human Genome Epidemiology (HuGE) Navigator: SLC13A4 (1 document)

    Export disorders for SLC13A4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC13A4 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with SLC13A4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and functional analysis of SUT-1, a sulfate transporter from human high endothelial venules. (PubMed id 10535998)1, 2, 3, 9 Girard J.-P.... Amalric F. (1999)
    2. Functional characterization and genomic organization of the human Na(+)-sulfate cotransporter hNaS2 gene (SLC13A4). (PubMed id 15607730)1, 2, 9 Markovich D.... Dawson P.A. (2005)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    5. Molecular analysis of the human SLC13A4 sulfate transp orter gene promoter. (PubMed id 23485456)1 Jefferis J....Dawson P.A. (2013)
    6. Human placental sulfate transporter mRNA profiling fro m term pregnancies identifies abundant SLC13A4 in syncytiotrophoblasts and SLC26 A2 in cytotrophoblasts. (PubMed id 23453247)1 Simmons D.G....Dawson P.A. (2013)
    7. Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters. (PubMed id 16211368)1 Pajor A.M. (2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26266 HGNC: 15827 AceView: SLC13A4 Ensembl:ENSG00000164707 euGenes: HUgn26266
    ECgene: SLC13A4 H-InvDB: SLC13A4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC13A4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC13A4 gene:
    Search GeneIP for patents involving SLC13A4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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