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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC13A2 Gene

protein-coding   GIFtS: 59
GCID: GC17P026800

solute carrier family 13 (sodium-dependent dicarboxylate...
 Explore 5 diseases affiliated with
SLC13A2 via
MalaCards
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 Human Malady Compendium 
Biological research products
for SLC13A2    

Aliases
for SLC13A2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Solute Carrier Family 13 (Sodium-Dependent Dicarboxylate Transporter),
Member 21 2
     Na(+)/Dicarboxylate Cotransporter 12 3
NaDC-11 2 3     NaCT2
NADC12 3 5     Na(+)-Coupled Citrate Transporter2
Renal Sodium/Dicarboxylate Cotransporter2 3     Solute Carrier Family 13 Member 22
SDCT12 3     

External Ids:    HGNC: 109171   Entrez Gene: 90582   Ensembl: ENSG000000072167   OMIM: 6041485   UniProtKB: Q131833   
ORGUL members:         
NONCODE:n407833    

Export aliases for SLC13A2 gene to outside databases

Previous GC identifers: GC17P026645 GC17P028700 GC17P026652 GC17P026946 GC17P023824 GC17P023009


Summaries
for SLC13A2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: S13A2_HUMAN, Q13183
Function: Cotransport of sodium ions and dicarboxylates such as succinate and citrate

Gene Wiki entry for SLC13A2


Genomic Views
for SLC13A2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010799.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC13A2 gene promoter:
         Max1   Tal-1   GATA-3   MyoD   LUN-1   STAT5A   AP-4   E47   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC13A2 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC13A2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC13A2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.2   Ensembl cytogenetic band:  17q11.2   HGNC cytogenetic band: 17p13.2

SLC13A2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC13A2 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P026800:  view genomic region     (about GC identifiers)

Start:
 26,800,311 bp from pter      End:
 26,824,799 bp from pter
Size:
 24,489 bases      Orientation:
 plus strand

Proteins
for SLC13A2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: S13A2_HUMAN, Q13183 (See protein sequence)
Recommended Name: Solute carrier family 13 member 2  
Size: 592 amino acids; 64410 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: B2RBI9 Q4VAR7

Explore the universe of human proteins at neXtProt for SLC13A2: NX_Q13183

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q13183

    • SLC13A2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001139447.1  NP_003975.1  

    ENSEMBL proteins: 
     ENSP00000392411   ENSP00000316202   ENSP00000463457   ENSP00000463421   ENSP00000464074  
     ENSP00000441935   ENSP00000440802  
    Reactome Protein details: Q13183
    Human Recombinant Protein Products: 
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    Novus Biologicals SLC13A2 Protein
    Novus Biologicals SLC13A2 Lysate
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SLC13A2

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005624membrane fraction ----
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane TAS8967342
    GO:0016020membrane TAS8967342


    SLC13A2 for ontologies           About GeneDecksing



    SLC13A2 Antibody Products: 
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    Uscn ELISAs and CLIAs for SLC13A2

    Protein Domains /
    Families
    for SLC13A2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC13A2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001898 Na/sul_symport

    Graphical View of Domain Structure for InterPro Entry Q13183

    ProtoNet protein and cluster: Q13183

    1 Blocks protein family: IPB001898 Sodium/sulphate symporter

    UniProtKB/Swiss-Prot: S13A2_HUMAN, Q13183
    Similarity: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily


    Function
    for SLC13A2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: S13A2_HUMAN, Q13183
    Function: Cotransport of sodium ions and dicarboxylates such as succinate and citrate

         Genatlas biochemistry entry for SLC13A2:
    solute carrier family 13,member A2,sodium dependent dicarboxylate transporter,located in proximal tubule,kidney

    miRNA
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    hsa-miR-485-5p hsa-miR-301b hsa-miR-148b hsa-miR-301a hsa-miR-3666 hsa-miR-152 hsa-miR-454 hsa-miR-4295
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity ----
    GO:0015361low affinity sodium:dicarboxylate symporter activity TAS8967342


    SLC13A2 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Slc13a2tm1Smch for SLC13A2
         2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Slc13a2):
     homeostasis/metabolism  renal/urinary system 

    SLC13A2 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for SLC13A2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1SLC-mediated transmembrane transport
    		SLC-mediated transmembrane transport1.00
    		Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    		Transmembrane transport of small molecules0.50
    2Bile salt and organic anion SLC transporters
    		Bile salt and organic anion SLC transporters1.00
    		Sodium-coupled sulphate, di- and tri-carboxylate transporters0.42

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5        Reactome Pathways for SLC13A2
        Sodium-coupled sulphate, di- and tri-carboxylate transporters
    Bile salt and organic anion SLC transporters
    SLC-mediated transmembrane transport
    Transmembrane transport of small molecules
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds



    SLC13A2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC13A2

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport TAS8967342
    GO:0006814sodium ion transport ----
    GO:0055085transmembrane transport TAS--


    SLC13A2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC13A2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC13A2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC13A2

    1 HMDB Compound for SLC13A2    About this table
    CompoundSynonyms CAS #PubMed Ids
    SodiumSodium (see all 2)7440-23-5--

    1 DrugBank Compound for SLC13A2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Succinic acid1,2-Ethanedicarboxylic acid (see all 8)110-15-6target--16735460 16030212 15561973 16188913

    9 Novoseek chemical compound relationships for SLC13A2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    dicarboxylate 93.1 19 10360950 (2), 10446305 (2), 9668069 (2), 10548552 (2) (see all 14)
    flufenamate 84.7 1 8946005 (1)
    succinate 82.6 12 10446305 (2), 18194662 (2), 10360950 (1), 11399753 (1) (see all 10)
    citrate 76.9 13 14973148 (3), 18161988 (2), 8946005 (2), 11399753 (1) (see all 8)
    glutaric acid 70.5 1 8946005 (1)
    lithium 63.1 2 8946005 (1), 9668069 (1)
    sodium 55.2 6 10360950 (1), 11399753 (1), 18161988 (1), 15774465 (1) (see all 6)
    furosemide 39.7 1 8946005 (1)
    cysteine 23.2 7 10548552 (7)

    Search CenterWatch for drugs/clinical trials and news about SLC13A2 / S13A2 

    Transcripts
    for SLC13A2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SLC13A2 gene (3 alternative transcripts): 
    NM_001145976.1  NM_001145975.1  NM_003984.3  

    Unigene Cluster for SLC13A2:

    Solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
    Hs.102307  [show with all ESTs]
    Unigene Representative Sequence: NM_001145975
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000444914(uc010wan.2) ENST00000314669(uc002hbh.3 uc010wao.2)
    ENST00000577903(uc010wal.1) ENST00000541739 ENST00000579281 ENST00000459818
    ENST00000545060 ENST00000537681(uc010wam.2 uc002hbi.3)

    miRNA
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    hsa-miR-485-5p hsa-miR-301b hsa-miR-148b hsa-miR-301a hsa-miR-3666 hsa-miR-152 hsa-miR-454 hsa-miR-4295
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC13A2 (see all 7)
    OriGene shRNA RFP: SLC13A2
    OriGene siRNA: SLC13A2
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AK091926.1 AK298388.1 AK303909.1 AK314684.1 BC096277.1 BC096278.1 BC096279.1 NR_027384.1 
    U26209.1 

    3 DOTS entries:

    DT.427910  DT.99999837  DT.100744154 

    16 AceView cDNA sequences:

    BX957019 CD617792 BX283772 AI057450 BE252472 AA603049 BI761183 CD617795 
    BM853859 BE256673 AK091926 U26209 BX483660 NM_003984 CK429895 AW024214 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SLC13A2    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b · 14c
    SP1:                                                                                                                  
    SP2:                    -           -                                                                                 
    SP3:                                -                                                                                 
    SP4:                    -     -     -                                                                                 


    ECgene alternative splicing isoforms for SLC13A2

    Expression
    for SLC13A2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC13A2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCCTCTCTGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SLC13A2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    4 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor CellsMotor Neurons
    BrainMedulla OblongataBrain
    Neural TubeMetencephalonNeural Tube
    Spinal CordSpinal Ventral ColumnsSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Endoderm progenitor-like cells (Generation and expan...)

    See SLC13A2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC13A2

    SOURCE GeneReport for Unigene cluster: Hs.102307
        SABiosciences Custom PCR Arrays for SLC13A2
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    In Situ
    Assay Products:     
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    Orthologs
    for SLC13A2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for SLC13A2 gene from 9/28 species (see all 28)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SLC13A21 solute carrier family 13 (sodium-dependent dicarboxylate more 65.33(n)
    65.21(a)    		   427830  XM_425404.2  XP_425404.2 
    lizard
    (Anolis carolinensis)    		 Reptilia SLC13A26
    		 --
    		 59(a)
    		 1 ↔ 1
    		 GL343470.1(530255-542376)
    African clawed frog
    (Xenopus laevis)    		 Amphibia nadc2-A-prov2 sodium/dicarboxylate cotransporter NaDC-2 72.69(n)    U87318.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.42712 Danio rerio mRNA similar to solute carrier family 13, more 75.86(n)    BC044437.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Indy-23
    Indy1    		 transport sodium:dicarboxylate cotransporter3
    I'm not dead yet1    		 34(a)3
    53.51(n)1
    41.19(a)1    		   400491  NM_168778.11  NP_730363.21 
    worm
    (Caenorhabditis elegans)    		 Secernentea F31F6.63 Na+/sulphate co-transporter like 38(a)
    (best of 3)    		   X(14930379-14933500)   --
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons TDT1 tonoplast dicarboxylate transporter 49.01(n)
    40.62(a)    		   834806  NM_124129.3  NP_199567.1 
    rice
    (Oryza sativa)    		 Liliopsida Os09g04849001 hypothetical protein 51.84(n)
    39.87(a)    		   4347418  NM_001070051.1  NP_001063516.1 
    E. coli
    (Escherichia coli)    		 Gamma proteobacteria yfbS6
    		 predicted transporter
    		 12(a)
    		 possible ortholog
    		 Chromosome(2407542-2409374)


    ENSEMBL Gene Tree for SLC13A2 (if available)
    TreeFam Gene Tree for SLC13A2 (if available) 

    Paralogs
    for SLC13A2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC13A2 gene
    SLC13A52  SLC13A42  SLC13A12  SLC13A32  
    5 SIMAP similar genes for SLC13A2 using alignment to 8 protein entries:     S13A2_HUMAN (see all proteins):
    DKFZp686E17257    SLC13A5    SLC13A3    SLC13A1    SLC13A4

    SLC13A2 for paralogs           About GeneDecksing



    Genomic Variants
    for SLC13A2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/444 NCBI SNPs in SLC13A2 are shown (see all 444)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 17 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs2005564781,2
    		C--26798672(+) GGGCCC/TGGTTT 3 -- us2k10--------
    rs782855051,2
    		C--26798702(+) GTGGC-/CTCTCCTT 3 -- us2k10--------
    rs739891181,2
    		C,--26798759(+) TCGGGG/ACATTG 3 -- us2k12Minor allele frequency- A:0.09WA 120
    rs1865937011,2
    		--26798832(+) GGGCAA/GGTGGC 3 -- us2k10--------
    rs285855431,2
    		C,F,--26798960(+) ATCCCT/CCTGAC 3 -- us2k15Minor allele frequency- C:0.15NA WA 126
    rs1450235661,2
    		--26799108(+) CCCCCA/GCAAAT 3 -- us2k10--------
    rs1907496941,2
    		--26799128(+) AACCAC/TGCAGA 3 -- us2k10--------
    rs1151695741,2
    		--26799245(+) GGATCA/GTCATA 3 -- us2k11Minor allele frequency- G:0.01WA 118
    rs801995251,2
    		--26799402(+) ACACAC/TACACA 3 -- us2k12Minor allele frequency- T:0.45CSA WA 120
    rs1477479881,2
    		--26799408(+) ACACAC/TGCATG 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for SLC13A2 (26800311 - 26824799 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SLC13A2: --
    Human Gene Mutation Database (HGMD): SLC13A2

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for SLC13A2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC13A2 for disorders           About GeneDecksing

    OMIM gene information: 604148    OMIM disorders: --

    5 diseases for SLC13A2:    About MalaCards
    diastrophic dysplasia    nephrolithiasis    colon carcinoma    pharyngitis
    carcinoma

    2 diseases from the University of Copenhagen DISEASES database for SLC13A2:
    Nephrolithiasis     Diastrophic dysplasia

    1 Novoseek disease relationship for SLC13A2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    metabolic acidosis 40.1 1 10446305 (1)

    Human Genome Epidemiology (HuGE) Navigator: SLC13A2 (2 documents)

    Export disorders for SLC13A2 gene to outside databases

    Publications
    for SLC13A2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC13A2 gene, integrated from 9 sources (see all 35):
    (articles sorted by number of sources associating them with SLC13A2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and functional expression of a sodium-dicarboxylate cotransporter from human kidney. (PubMed id 8967342)1, 2, 3, 9 Pajor A.M. (1996)
    2. Assignment of the sodium-dependent dicarboxylate transporter gene (SLC13A2 alias NaDC-1) to human chromosome region 17p11.1-->q11.1 by radiation hybrid mapping and fluorescence in situ hybridization. (PubMed id 10343111)1, 3, 9 Mann S.S....Holmes R.P. (1999)
    3. Associations between renal sodium-citrate cotransporter (hNaDC-1) gene polymorphism and urinary citrate excretion in recurrent renal calcium stone formers and normal controls. (PubMed id 17470169)1, 2, 9 Okamoto N....Kitamura T. (2007)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Expression of EGFP/SDCT1 fusion protein, subcellular localization signal analysis, tissue distribution and electrophysiological function study. (PubMed id 15620109)1, 9 Bai X....Peng L. (2004)
    7. Threonine-509 is a determinant of apparent affinity for both substrate and cations in the human Na+/dicarboxylate cotransporter. (PubMed id 18161988)1, 9 Weerachayaphorn J. and Pajor A.M. (2008)
    8. Conformationally sensitive residues in extracellular loop 5 of the Na+/dicarboxylate co-transporter. (PubMed id 15774465)1, 9 Pajor A.M. and Randolph K.M. (2005)
    9. Substrate specificity of the human renal sodium dicarboxylate cotransporter, hNaDC-3, under voltage-clamp conditions. (PubMed id 15561973)7, 9 Burckhardt B.C....Burckhardt G. (2005)
    10. Synthesis, maturation, and trafficking of human Na+-d icarboxylate cotransporter NaDC1 requires the chaperone activity of cyclophilin B. (PubMed id 21257749)1 Bergeron M.J....Hediger M.A. (2011)

    External Searches for SLC13A2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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    Genome Databases showing SLC13A2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9058 HGNC: 10917 AceView: SLC13A2 Ensembl:ENSG00000007216 euGenes: HUgn9058
    ECgene: SLC13A2 H-InvDB: SLC13A2

    Other Databases showing SLC13A2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SLC13A2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC13A2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC13A2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC13A2 gene:
    Search GeneIP for patents involving SLC13A2

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