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Aliases for SLC10A3 Gene

Aliases for SLC10A3 Gene

  • Solute Carrier Family 10, Member 3 2 3
  • P3 3 4 6
  • DXS253E 3 4
  • Solute Carrier Family 10 (Sodium/Bile Acid Cotransporter Family), Member 3 3
  • Solute Carrier Family 10 Member 3 4
  • P3 Protein 3
  • Protein P3 3

External Ids for SLC10A3 Gene

Previous GeneCards Identifiers for SLC10A3 Gene

  • GC0XM151301
  • GC0XM152183
  • GC0XM153279
  • GC0XM153368
  • GC0XM153715
  • GC0XM142292

Summaries for SLC10A3 Gene

Entrez Gene Summary for SLC10A3 Gene

  • This gene maps to a GC-rich region of the X chromosome and was identified by its proximity to a CpG island. It is thought to be a housekeeping gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2008]

GeneCards Summary for SLC10A3 Gene

SLC10A3 (Solute Carrier Family 10, Member 3) is a Protein Coding gene. GO annotations related to this gene include bile acid:sodium symporter activity. An important paralog of this gene is SLC10A6.

UniProtKB/Swiss-Prot for SLC10A3 Gene

  • The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions

Gene Wiki entry for SLC10A3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC10A3 Gene

Genomics for SLC10A3 Gene

Regulatory Elements for SLC10A3 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SLC10A3 Gene

154,487,306 bp from pter
154,490,690 bp from pter
3,385 bases
Minus strand

Genomic View for SLC10A3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC10A3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC10A3 Gene

Proteins for SLC10A3 Gene

  • Protein details for SLC10A3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    P3 protein
    Protein Accession:
    Secondary Accessions:
    • Q5HY79
    • Q9BSL2

    Protein attributes for SLC10A3 Gene

    477 amino acids
    Molecular mass:
    50333 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SLC10A3 Gene


neXtProt entry for SLC10A3 Gene

Proteomics data for SLC10A3 Gene at MOPED

Post-translational modifications for SLC10A3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC10A3 Gene

Antibody Products

No data available for DME Specific Peptides for SLC10A3 Gene

Domains for SLC10A3 Gene

Gene Families for SLC10A3 Gene

Protein Domains for SLC10A3 Gene

Suggested Antigen Peptide Sequences for SLC10A3 Gene

Graphical View of Domain Structure for InterPro Entry



  • P09131
  • Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
genes like me logo Genes that share domains with SLC10A3: view

Function for SLC10A3 Gene

Molecular function for SLC10A3 Gene

UniProtKB/Swiss-Prot Function:
The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions

Gene Ontology (GO) - Molecular Function for SLC10A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008508 bile acid:sodium symporter activity IBA --
genes like me logo Genes that share ontologies with SLC10A3: view

Animal Model Products

CRISPR Products

miRNA for SLC10A3 Gene

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC10A3

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SLC10A3 Gene

Localization for SLC10A3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC10A3 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SLC10A3 Gene COMPARTMENTS Subcellular localization image for SLC10A3 gene
Compartment Confidence
plasma membrane 3
cytoskeleton 1
nucleus 1

Gene Ontology (GO) - Cellular Components for SLC10A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane IBA --
GO:0016020 membrane --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with SLC10A3: view

Pathways for SLC10A3 Gene

SuperPathways for SLC10A3 Gene

No Data Available

Interacting Proteins for SLC10A3 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000263512 for SLC10A3 Gene via STRING

Gene Ontology (GO) - Biological Process for SLC10A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006814 sodium ion transport --
GO:0010033 response to organic substance --
GO:0015721 bile acid and bile salt transport IBA --
GO:0032526 response to retinoic acid IEA --
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC10A3: view

No data available for Pathways by source for SLC10A3 Gene

Compounds for SLC10A3 Gene

(1) HMDB Compounds for SLC10A3 Gene

Compound Synonyms Cas Number PubMed IDs
  • Sodium
genes like me logo Genes that share compounds with SLC10A3: view

Transcripts for SLC10A3 Gene

Unigene Clusters for SLC10A3 Gene

Solute carrier family 10 (sodium/bile acid cotransporter family), member 3:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC10A3

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC10A3 Gene

No ASD Table

Relevant External Links for SLC10A3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC10A3 Gene

mRNA expression in normal human tissues for SLC10A3 Gene

SOURCE GeneReport for Unigene cluster for SLC10A3 Gene Hs.522826

genes like me logo Genes that share expressions with SLC10A3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for SLC10A3 Gene

Orthologs for SLC10A3 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC10A3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SLC10A3 35
  • 86.65 (n)
  • 86.37 (a)
SLC10A3 36
  • 86 (a)
(Canis familiaris)
Mammalia SLC10A3 35
  • 89.1 (n)
  • 88.47 (a)
SLC10A3 36
  • 88 (a)
(Mus musculus)
Mammalia Slc10a3 35
  • 83.44 (n)
  • 85.84 (a)
Slc10a3 16
Slc10a3 36
  • 86 (a)
(Pan troglodytes)
Mammalia SLC10A3 35
  • 98.95 (n)
  • 98.95 (a)
(Rattus norvegicus)
Mammalia Slc10a3 35
  • 84.07 (n)
  • 85.84 (a)
(Monodelphis domestica)
Mammalia SLC10A3 36
  • 62 (a)
(Ornithorhynchus anatinus)
Mammalia SLC10A3 36
  • 69 (a)
(Anolis carolinensis)
Reptilia SLC10A3 36
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia slc10a3 35
  • 59.27 (n)
  • 59.6 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.9703 35
(Danio rerio)
Actinopterygii slc10a3 35
  • 66.35 (n)
  • 60.71 (a)
slc10a3 36
  • 56 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG11655 36
  • 22 (a)
CG9903 36
  • 19 (a)
(Caenorhabditis elegans)
Secernentea Y71G10AR.4 36
  • 18 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 31 (a)
-- 36
  • 31 (a)
Species with no ortholog for SLC10A3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC10A3 Gene

Gene Tree for SLC10A3 (if available)
Gene Tree for SLC10A3 (if available)

Paralogs for SLC10A3 Gene

Paralogs for SLC10A3 Gene

Selected SIMAP similar genes for SLC10A3 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with SLC10A3: view

Variants for SLC10A3 Gene

Sequence variations from dbSNP and Humsavar for SLC10A3 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs5945435 -- 154,489,490(+) TTTGA(C/G)CTCCC intron-variant, upstream-variant-2KB
rs5986983 -- 154,489,674(+) CCTGC(C/T)AGAAC intron-variant, upstream-variant-2KB
rs5987268 -- 154,490,637(+) CTGGC(A/C)GGCAG utr-variant-5-prime, upstream-variant-2KB
rs6655248 -- 154,490,171(+) CCAGA(A/T)CCCAC intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs6655249 -- 154,490,222(+) CACCC(A/G)CAAGG intron-variant, upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for SLC10A3 Gene

Variant ID Type Subtype PubMed ID
esv33199 CNV Gain+Loss 17666407
esv33784 CNV Gain+Loss 17666407
nsv519042 CNV Gain 19592680

Relevant External Links for SLC10A3 Gene

HapMap Linkage Disequilibrium report
Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC10A3 Gene

Disorders for SLC10A3 Gene

No disorders were found for SLC10A3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SLC10A3 Gene

Publications for SLC10A3 Gene

  1. Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci. (PMID: 8733135) Chen E.Y. … D'Urso M. (Hum. Mol. Genet. 1996) 2 3 4
  2. CpG islands of the X chromosome are gene associated. (PMID: 3186440) Alcalay M. … Toniolo D. (Nucleic Acids Res. 1988) 3 4
  3. Linkage and sequence conservation of the X-linked genes DXS253E (P3) and DXS254E (GdX) in mouse and man. (PMID: 1973144) Filippi M. … Toniolo D. (Genomics 1990) 23
  4. Structural studies of the enveloped dsRNA bacteriophage phi 6 of Pseudomonas syringae by Raman spectroscopy. I. The virion and its membrane envelope. (PMID: 8464060) Li T. … Thomas G.J. (J. Mol. Biol. 1993) 23
  5. Immunological reactivity of baculovirus-expressed enterovirus proteins. (PMID: 9300386) Dahllund L. … HyypiAo T. (J. Virol. Methods 1997) 23

Products for SLC10A3 Gene

Sources for SLC10A3 Gene

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