Aliases for SLAMF1 Gene
External Ids for SLAMF1 Gene
Previous HGNC Symbols for SLAMF1 Gene
Previous GeneCards Identifiers for SLAMF1 Gene
GeneCards Summary for SLAMF1 Gene
SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1) is a Protein Coding gene. Diseases associated with SLAMF1 include measles and subacute sclerosing panencephalitis. Among its related pathways are Influenza A. GO annotations related to this gene include receptor activity and antigen binding.
UniProtKB/Swiss-Prot for SLAMF1 Gene
High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates
(Microbial infection) Acts as a receptor for measles virus.