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Aliases for SLAMF1 Gene

Aliases for SLAMF1 Gene

  • Signaling Lymphocytic Activation Molecule Family Member 1 2 3 5
  • SLAM Family Member 1 3 4
  • CDw150 3 4
  • IPO-3 3 4
  • SLAM 3 4
  • Signaling Lymphocytic Activation Molecule 2
  • CD150 Antigen 4
  • CD150 3

External Ids for SLAMF1 Gene

Previous HGNC Symbols for SLAMF1 Gene

  • SLAM

Previous GeneCards Identifiers for SLAMF1 Gene

  • GC01M157796
  • GC01M157392
  • GC01M158844
  • GC01M131936

Summaries for SLAMF1 Gene

GeneCards Summary for SLAMF1 Gene

SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1) is a Protein Coding gene. Diseases associated with SLAMF1 include measles and subacute sclerosing panencephalitis. Among its related pathways are IgA-Producing B Cells in the Intestine and Influenza A. GO annotations related to this gene include receptor activity and antigen binding.

UniProtKB/Swiss-Prot for SLAMF1 Gene

  • Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAMF1 signaling seem to exist: one depending on SH2D1A (and perhaps SH2D1B) and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. Initially it has been proposed that association with SH2D1A prevents binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2 (PubMed:11806999). However, signaling is also regulated by SH2D1A which can simultaneously interact with and recruit FYN which subsequently phosphorylates and activates SLAMF1 (PubMed:12458214). Mediates IL-2-independent proliferation of activated T-cells during immune responses and induces IFN-gamma production (By similarity). Downstreaming signaling involves INPP5D, DOK1 and DOK2 leading to inhibited IFN-gamma production in T-cells, and PRKCQ, BCL10 and NFKB1 leading to increased T-cell activation and Th2 cytokine production (By similarity). Promotes T-cell receptor-induced IL-4 secretion by CD4(+) cells (By similarity). Inhibits antigen receptor-mediated production of IFN-gamma, but not IL-2, in CD4(-)/CD8(-) T-cells (By similarity). Required for IL-4 production by germinal centers T follicular helper (T(Fh))cells (By similarity). May inhibit CD40-induced signal transduction in monocyte-derived dendritic cells (PubMed:16317102). May play a role in a allergic responses and may regulate allergen-induced Th2 cytokine and Th1 cytokine secretion (By similarity). In conjunction with SLAMF6 controls the transition between positive selection and the subsequent expansion and differentiation of the thymocytic natural killer T (NKT) cell lineage. Involved in the peripheral differentiation of indifferent natural killer T (iNKT) cells toward a regulatory NKT2 type (By similarity). In macrophages involved in down-regulation of IL-12, TNF-alpha and nitric oxide in response to lipopolysaccharide (LPS) (By similarity). In B-cells activates the ERK signaling pathway independently of SH2D1A but implicating both, SYK and INPP5D, and activates Akt signaling dependent on SYK and SH2D1A (By similarity). In B-cells also activates p38 MAPK and JNK1 and JNK2 (PubMed:20231852). In conjunction with CD84/SLAMF5 and SLAMF6 may be a negative regulator of the humoral immune response (By similarity).

  • (Microbial infection) Acts as a receptor for measles virus; also including isoform 4 (PubMed:10972291, PubMed:25710480). Involved in innate immune response against Gram-negative bacteria in macrophages; probably recognizes OmpC and/or OmpF on the bacterial surface, regulates phagosome maturation and recruitment of the PI3K complex II (PI3KC3-C2) leading to accumulation of PdtIns(3)P and NOX2 activity in the phagosomes (PubMed:20818396).

Gene Wiki entry for SLAMF1 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLAMF1 Gene

Genomics for SLAMF1 Gene

Regulatory Elements for SLAMF1 Gene

Promoters for SLAMF1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SLAMF1 on UCSC Golden Path with GeneCards custom track

Genomic Location for SLAMF1 Gene

Chromosome:
1
Start:
160,608,100 bp from pter
End:
160,647,537 bp from pter
Size:
39,438 bases
Orientation:
Minus strand

Genomic View for SLAMF1 Gene

Genes around SLAMF1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLAMF1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLAMF1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLAMF1 Gene

Proteins for SLAMF1 Gene

  • Protein details for SLAMF1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13291-SLAF1_HUMAN
    Recommended name:
    Signaling lymphocytic activation molecule
    Protein Accession:
    Q13291
    Secondary Accessions:
    • Q5W172
    • Q9HBE8
    • W0HKK7

    Protein attributes for SLAMF1 Gene

    Size:
    335 amino acids
    Molecular mass:
    37231 Da
    Quaternary structure:
    • Interacts (via cytoplasmic domain) with SH2D1A and SH2D1B; SH2D1A mediates association with FYN; SH2D1A binds to phosphorylated and not phosphorylated ITSM 1 (PubMed:9774102, PubMed:11313386, PubMed:11806999, PubMed:12458214). Interacts (via cytoplasmic domain phosphorylated on tyrosine residues) with INPP5D and PTPN11; presence of SH2D1A facilitates binding to INPP5D (PubMed:11313386, PubMed:12458214). Interacts with MAP4K1 (PubMed:20231852). Interacts with PIK3C3, BECN1 and UVRAG; indicative for an association with PI3K complex II (PI3KC3-C2) (PubMed:20818396).
    • (Microbial infection) Interacts with measles hemagglutinin protein.

    Three dimensional structures from OCA and Proteopedia for SLAMF1 Gene

    Alternative splice isoforms for SLAMF1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLAMF1 Gene

Proteomics data for SLAMF1 Gene at MOPED

Post-translational modifications for SLAMF1 Gene

  • Phosphorylated on tyrosine residues by FYN.
  • Glycosylation at Asn 53, Asn 57, Asn 102, Asn 125, Asn 150, Asn 155, Asn 189, and Asn 217
  • Modification sites at PhosphoSitePlus

Other Protein References for SLAMF1 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Cloud-Clone Corp. Antibodies for SLAMF1

No data available for DME Specific Peptides for SLAMF1 Gene

Domains & Families for SLAMF1 Gene

Protein Domains for SLAMF1 Gene

Graphical View of Domain Structure for InterPro Entry

Q13291

UniProtKB/Swiss-Prot:

SLAF1_HUMAN :
  • The ITSMs (immunoreceptor tyrosine-based switch motifs) with the consensus sequence T-X-Y-X-X-[VI] present in SLAM family receptors have overlapping specificity for activating and inhibitory SH2 domain-containing binding partners. Especially they mediate the interaction with the SH2 domain of SH2D1A and SH2D1B. For SLAMF1 a two-out-of-three-pronged mechanism is proposed involving threonine (position -2), phosphorylated tyrosine (position 0) and valine/isoleucine (position +3). SH2D1A binding is mediated by either three prongs (for high affinity binding involving ITSM 1) or a combination of any two also including non-phosphorylated Tyr-281 of ITSM 1 thus providing a positive feedback loop implicating SH2D1A-dependent recruitment of activating FYN. ITSM 2 needs to be phosphorylated on Tyr-327 for SH2D1A binding.
Domain:
  • The ITSMs (immunoreceptor tyrosine-based switch motifs) with the consensus sequence T-X-Y-X-X-[VI] present in SLAM family receptors have overlapping specificity for activating and inhibitory SH2 domain-containing binding partners. Especially they mediate the interaction with the SH2 domain of SH2D1A and SH2D1B. For SLAMF1 a two-out-of-three-pronged mechanism is proposed involving threonine (position -2), phosphorylated tyrosine (position 0) and valine/isoleucine (position +3). SH2D1A binding is mediated by either three prongs (for high affinity binding involving ITSM 1) or a combination of any two also including non-phosphorylated Tyr-281 of ITSM 1 thus providing a positive feedback loop implicating SH2D1A-dependent recruitment of activating FYN. ITSM 2 needs to be phosphorylated on Tyr-327 for SH2D1A binding.
  • Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • Contains 1 Ig-like V-type (immunoglobulin-like) domain.
genes like me logo Genes that share domains with SLAMF1: view

Function for SLAMF1 Gene

Molecular function for SLAMF1 Gene

UniProtKB/Swiss-Prot Function:
Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAMF1 signaling seem to exist: one depending on SH2D1A (and perhaps SH2D1B) and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. Initially it has been proposed that association with SH2D1A prevents binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2 (PubMed:11806999). However, signaling is also regulated by SH2D1A which can simultaneously interact with and recruit FYN which subsequently phosphorylates and activates SLAMF1 (PubMed:12458214). Mediates IL-2-independent proliferation of activated T-cells during immune responses and induces IFN-gamma production (By similarity). Downstreaming signaling involves INPP5D, DOK1 and DOK2 leading to inhibited IFN-gamma production in T-cells, and PRKCQ, BCL10 and NFKB1 leading to increased T-cell activation and Th2 cytokine production (By similarity). Promotes T-cell receptor-induced IL-4 secretion by CD4(+) cells (By similarity). Inhibits antigen receptor-mediated production of IFN-gamma, but not IL-2, in CD4(-)/CD8(-) T-cells (By similarity). Required for IL-4 production by germinal centers T follicular helper (T(Fh))cells (By similarity). May inhibit CD40-induced signal transduction in monocyte-derived dendritic cells (PubMed:16317102). May play a role in a allergic responses and may regulate allergen-induced Th2 cytokine and Th1 cytokine secretion (By similarity). In conjunction with SLAMF6 controls the transition between positive selection and the subsequent expansion and differentiation of the thymocytic natural killer T (NKT) cell lineage. Involved in the peripheral differentiation of indifferent natural killer T (iNKT) cells toward a regulatory NKT2 type (By similarity). In macrophages involved in down-regulation of IL-12, TNF-alpha and nitric oxide in response to lipopolysaccharide (LPS) (By similarity). In B-cells activates the ERK signaling pathway independently of SH2D1A but implicating both, SYK and INPP5D, and activates Akt signaling dependent on SYK and SH2D1A (By similarity). In B-cells also activates p38 MAPK and JNK1 and JNK2 (PubMed:20231852). In conjunction with CD84/SLAMF5 and SLAMF6 may be a negative regulator of the humoral immune response (By similarity).
UniProtKB/Swiss-Prot Function:
(Microbial infection) Acts as a receptor for measles virus; also including isoform 4 (PubMed:10972291, PubMed:25710480). Involved in innate immune response against Gram-negative bacteria in macrophages; probably recognizes OmpC and/or OmpF on the bacterial surface, regulates phagosome maturation and recruitment of the PI3K complex II (PI3KC3-C2) leading to accumulation of PdtIns(3)P and NOX2 activity in the phagosomes (PubMed:20818396).

Gene Ontology (GO) - Molecular Function for SLAMF1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity TAS 7617038
genes like me logo Genes that share ontologies with SLAMF1: view
genes like me logo Genes that share phenotypes with SLAMF1: view

Animal Models for SLAMF1 Gene

MGI Knock Outs for SLAMF1:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SLAMF1 Gene

Localization for SLAMF1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLAMF1 Gene

Cell membrane; Single-pass type I membrane protein. Note=Present on the surface of B-cells and T-cells. Located at the plasma membrane contacts between neighboring T-cells (PubMed:11806999). {ECO:0000269 PubMed:11806999}.
Isoform 3: Secreted.
Isoform 4: Cell membrane. Note=Overexpressed isoform 4 is detected on the cell surface. In glioma cell lines endogenuous isoform 4 is detetced predominantly in the cytoplasm and colocalized with endoplasmic reticulum and Golgi markers. {ECO:0000269 PubMed:25710480}.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLAMF1 Gene COMPARTMENTS Subcellular localization image for SLAMF1 gene
Compartment Confidence
extracellular 5
plasma membrane 4
cytosol 2
endoplasmic reticulum 2
cytoskeleton 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for SLAMF1 Gene

Pathways & Interactions for SLAMF1 Gene

genes like me logo Genes that share pathways with SLAMF1: view

SIGNOR curated interactions for SLAMF1 Gene

Other effect:

Gene Ontology (GO) - Biological Process for SLAMF1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001779 natural killer cell differentiation IEA --
GO:0001787 natural killer cell proliferation IEA --
GO:0002277 myeloid dendritic cell activation involved in immune response IDA 16317102
GO:0002725 negative regulation of T cell cytokine production IEA --
GO:0006909 phagocytosis IEA --
genes like me logo Genes that share ontologies with SLAMF1: view

Drugs & Compounds for SLAMF1 Gene

(2) Drugs for SLAMF1 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(1) Additional Compounds for SLAMF1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with SLAMF1: view

Transcripts for SLAMF1 Gene

Unigene Clusters for SLAMF1 Gene

Signaling lymphocytic activation molecule family member 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLAMF1 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c
SP1: - -
SP2: - - - -
SP3: -
SP4:
SP5:

Relevant External Links for SLAMF1 Gene

GeneLoc Exon Structure for
SLAMF1
ECgene alternative splicing isoforms for
SLAMF1

Expression for SLAMF1 Gene

mRNA expression in normal human tissues for SLAMF1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for SLAMF1 Gene

This gene is overexpressed in Plasma (38.6), Peripheral blood mononuclear cells (9.2), CD8 Tcells (8.4), and Blymphocyte (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for SLAMF1 Gene



SOURCE GeneReport for Unigene cluster for SLAMF1 Gene Hs.523660

mRNA Expression by UniProt/SwissProt for SLAMF1 Gene

Q13291-SLAF1_HUMAN
Tissue specificity: Constitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation (PubMed:7617038). Activated B-cells express isoform 1, isoform 3 and a cytoplasmic isoform (PubMed:9091591). Isoform 4 is expressed in B-cells, primary T-cells, dendritic cells and macrophages. Isoform 4 is expressed in tumors of the central nervous system (PubMed:25710480).
genes like me logo Genes that share expression patterns with SLAMF1: view

Protein tissue co-expression partners for SLAMF1 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues for SLAMF1 Gene

Orthologs for SLAMF1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SLAMF1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SLAMF1 35
  • 78.64 (n)
  • 66.77 (a)
SLAMF1 36
  • 66 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLAMF1 35
  • 78.41 (n)
  • 65.97 (a)
SLAM 36
  • 65 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slamf1 35
  • 74.83 (n)
  • 62.09 (a)
Slamf1 16
Slamf1 36
  • 60 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia SLAMF1 35
  • 99.8 (n)
  • 99.7 (a)
SLAMF1 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Slamf1 35
  • 72.94 (n)
  • 60 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia SLAMF1 36
  • 31 (a)
OneToOne
chicken
(Gallus gallus)
Aves SLAMF1 35
  • 47.12 (n)
  • 35.26 (a)
SLAMF1 36
  • 30 (a)
OneToOne
Species with no ortholog for SLAMF1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SLAMF1 Gene

ENSEMBL:
Gene Tree for SLAMF1 (if available)
TreeFam:
Gene Tree for SLAMF1 (if available)

Paralogs for SLAMF1 Gene

(1) SIMAP similar genes for SLAMF1 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with SLAMF1: view

No data available for Paralogs for SLAMF1 Gene

Variants for SLAMF1 Gene

Sequence variations from dbSNP and Humsavar for SLAMF1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs2295612 - 160,646,913(+) AGCAC(A/G/T)AAGGT nc-transcript-variant, reference, missense, utr-variant-5-prime
rs3796504 - 160,610,759(+) CTCTG(G/T)AAGTG nc-transcript-variant, reference, missense
VAR_035524 A breast cancer sample
rs1726 -- 160,608,214(-) GTTAC(A/T)GCGGG utr-variant-3-prime
rs149160 -- 160,615,764(-) ggaca(C/G)tcatc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLAMF1 Gene

Variant ID Type Subtype PubMed ID
nsv872491 CNV Loss 21882294
nsv831703 CNV Gain 17160897
nsv831714 CNV Gain 17160897

Variation tolerance for SLAMF1 Gene

Residual Variation Intolerance Score: 41.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.99; 68.28% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SLAMF1 Gene

HapMap Linkage Disequilibrium report
SLAMF1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLAMF1 Gene

Disorders for SLAMF1 Gene

MalaCards: The human disease database

(3) MalaCards diseases for SLAMF1 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
measles
  • morbilli
subacute sclerosing panencephalitis
  • immunosuppressive measles encephalitis
lymphoproliferative syndrome, x-linked, 1
  • lymphoproliferative syndrome, x-linked
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for SLAMF1

Genetic Association Database (GAD)
SLAMF1
Human Genome Epidemiology (HuGE) Navigator
SLAMF1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SLAMF1
genes like me logo Genes that share disorders with SLAMF1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SLAMF1 Gene

Publications for SLAMF1 Gene

  1. Absence of SLAM mutations in EBV-associated lymphoproliferative disease patients. (PMID: 12629654) Ferrand V. … Yin L. (J. Med. Virol. 2003) 3 4 48 67
  2. Measles virus infection of alveolar macrophages and dendritic cells precedes spread to lymphatic organs in transgenic mice expressing human signaling lymphocytic activation molecule (SLAM, CD150). (PMID: 20042501) Ferreira C.S. … Cattaneo R. (J. Virol. 2010) 3 23
  3. Enhancement of anti-tumor activity in vitro and in vivo by CD150 and SAP. (PMID: 17692919) Mehrle S. … MAorten A. (Mol. Immunol. 2008) 3 23
  4. SLAM/SLAM interactions inhibit CD40-induced production of inflammatory cytokines in monocyte-derived dendritic cells. (PMID: 16317102) RActhi B. … LA!nyi A. (Blood 2006) 3 23
  5. Identification of amino acid residues involved in the interaction between measles virus Haemagglutin (MVH) and its human cell receptor (signaling lymphocyte activation molecule, SLAM). (PMID: 16889684) Xu Q. … Liu Y. (J. Biochem. Mol. Biol. 2006) 3 23

Products for SLAMF1 Gene

Sources for SLAMF1 Gene

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