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SLAIN2 Gene

protein-coding   GIFtS: 50
GCID: GC04P048343

SLAIN Motif Family, Member 2

(Previous name: KIAA1458)
(Previous symbol: KIAA1458)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
SLAIN Motif Family, Member 21 2
KIAA14581 2 3
SLAIN Motif-Containing Protein 22

External Ids:    HGNC: 292821   Entrez Gene: 576062   Ensembl: ENSG000001091717   OMIM: 6104925   UniProtKB: Q9P2703   

Export aliases for SLAIN2 gene to outside databases

Previous GC identifers: GC04P047991 GC04P047663


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SLAIN2 Gene:
SLAIN2 (SLAIN motif family, member 2) is a protein-coding gene. Diseases associated with SLAIN2 include intrahepatic cholangiocarcinoma, and cholangiocarcinoma. An important paralog of this gene is SLAIN1.

UniProtKB/Swiss-Prot: SLAI2_HUMAN, Q9P270
Function: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization.
Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule
cytoskeleton during interphase




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000004.12  NT_006238.12  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLAIN2 gene promoter:
         E2F-3a   E2F-4   E2F-5   Pbx1a   Nkx2-2   E2F-2   E2F-1   E2F   HOXA5   ARP-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for SLAIN2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLAIN2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p11   Ensembl cytogenetic band:  4p11   HGNC cytogenetic band: 4p12

SLAIN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLAIN2 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P048343:  view genomic region     (about GC identifiers)

Start:
48,343,339 bp from pter      End:
48,428,229 bp from pter
Size:
84,891 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SLAI2_HUMAN, Q9P270 (See protein sequence)
Recommended Name: SLAIN motif-containing protein 2  
Size: 581 amino acids; 62543 Da
Subunit: Interacts with CLIP1, CLIP2, CKAP5, CLASP1, MAPRE1 and MAPRE3
Sequence caution: Sequence=AAH31691.2; Type=Erroneous initiation; Sequence=BAA95982.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for SLAIN2:
3RDV (3D)    
Secondary accessions: A8K4P1 Q8N5R3

Explore the universe of human proteins at neXtProt for SLAIN2: NX_Q9P270

Explore proteomics data for SLAIN2 at MOPED

Post-translational modifications: 

  • Is highly phosphorylated during mitosis, but not during interphase. The highly phosphorylated form does not
    localize at microtubule plus ends and does not interact with MAPRE1 or CKAP51
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SLAIN2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065897.1  
    ENSEMBL proteins: 
     ENSP00000264313   ENSP00000425923   ENSP00000426744   ENSP00000424473  

    SLAIN2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026179 Slain

    Graphical View of Domain Structure for InterPro Entry Q9P270

    ProtoNet protein and cluster: Q9P270

    UniProtKB/Swiss-Prot: SLAI2_HUMAN, Q9P270
    Domain: The N-terminus forms a two-stranded coiled coil
    Similarity: Belongs to the SLAIN motif-containing family


    SLAIN2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SLAI2_HUMAN, Q9P270
    Function: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization.
    Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule
    cytoskeleton during interphase

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    SLAIN2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SLAIN2:
     Decreased viability with pacli 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLAIN2
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLAIN2
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    miRNA
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    miRTarBase miRNAs that target SLAIN2:
    hsa-mir-21-5p (MIRT030692)

    Block miRNA regulation of human, mouse, rat SLAIN2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SLAIN2 (see all 154):
    hsa-miR-640 hsa-miR-106a hsa-miR-3653 hsa-miR-3074-3p hsa-miR-519a hsa-miR-637 hsa-miR-208b hsa-miR-376a*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLAIN2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SLAI2_HUMAN, Q9P270: Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules. Detected at the plus end of
    growing microtubules
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    nucleus3
    cytosol2

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005813centrosome IDA--
    GO:0015630microtubule cytoskeleton IDA--

    SLAIN2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLAIN2
    Interactions:

        Search GeneGlobe Interaction Network for SLAIN2

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for SLAIN2 (Q9P2702, 3 ENSP000002643134) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAZP631042, 3, ENSP000003095034MINT-3306673 I2D: score=1 STRING: ENSP00000309503
    CKAP5Q140083, ENSP000003465664I2D: score=1 STRING: ENSP00000346566
    GRB2ENSP000003390074STRING: ENSP00000339007
    SH3KBP1ENSP000003809214STRING: ENSP00000380921
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007020microtubule nucleation IMP--
    GO:0031113regulation of microtubule polymerization ----
    GO:0031116positive regulation of microtubule polymerization IMP--
    GO:0031122cytoplasmic microtubule organization IMP--

    SLAIN2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLAIN2 (SLAI2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SLAIN2 gene: 
    NM_020846.1  

    Unigene Cluster for SLAIN2:

    SLAIN motif family, member 2
    Hs.479677  [show with all ESTs]
    Unigene Representative Sequence: NM_020846
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000264313(uc003gya.4) ENST00000506375 ENST00000512093 ENST00000505131
    ENST00000510595
    miRNA
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    Block miRNA regulation of human, mouse, rat SLAIN2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SLAIN2 (see all 154):
    hsa-miR-640 hsa-miR-106a hsa-miR-3653 hsa-miR-3074-3p hsa-miR-519a hsa-miR-637 hsa-miR-208b hsa-miR-376a*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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      QuantiTect SYBR Green Assays in human, mouse, rat SLAIN2
      QuantiFast Probe-based Assays in human, mouse, rat SLAIN2

    Additional mRNA sequence: 

    AB040891.1 AK025264.1 AK026476.1 AK096470.1 AK291006.1 BC006139.1 BC007701.2 BC012067.1 
    BC031691.2 BC040993.1 

    8 DOTS entries:

    DT.313380  DT.100031691  DT.95135522  DT.95240369  DT.121272447  DT.100760647  DT.91812850  DT.97868506 

    Selected AceView cDNA sequences (see all 215):

    AW368119 AW771201 BX956251 AI138449 AW073808 AI701478 AA417303 BM795243 
    BE551691 AI147683 AI718401 AI498485 AA011669 AI992106 AA456668 AI695423 
    AI579993 AW589990 AK025264 AI566101 AI926631 AI949699 AW771350 AI275013 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SLAIN2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9
    SP1:                          -                       -     -           -         
    SP2:                                                  -                           
    SP3:                                                                              


    ECgene alternative splicing isoforms for SLAIN2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLAIN2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SLAIN2 Expression
    About this image


    SLAIN2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Liver (Hepatobiliary System)
             Liver Lobule
    SLAIN2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLAIN2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.479677

    UniProtKB/Swiss-Prot: SLAI2_HUMAN, Q9P270
    Tissue specificity: Widely expressed with highest levels in adult liver, testis and ovary, and lowest levels in
    adult pancreas and spleen and in fetal brain

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SLAIN2 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slain21 , 5 SLAIN motif family, member 21, 5 91.03(n)1
    94.14(a)1
      5 (38.44 cM)5
    759911  NM_153567.31  NP_705795.21 
     729143045 
    chicken
    (Gallus gallus)
    Aves SLAIN21 SLAIN motif family, member 2 78.53(n)
    79.54(a)
      422766  XM_004936042.1  XP_004936099.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLAIN26
    SLAIN motif family, member 2
    70(a)
    1 ↔ 1
    GL343293.1(763927-802624)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004914881 SLAIN motif-containing protein 2-like 70.28(n)
    68.74(a)
      100491488  XM_004911206.1  XP_004911263.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufd58c022 wufd58c02 73.96(n)   326023  BC055660.1 


    ENSEMBL Gene Tree for SLAIN2 (if available)
    TreeFam Gene Tree for SLAIN2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLAIN2 gene
    SLAIN12  
    1 SIMAP similar gene for SLAIN2 using alignment to 4 protein entries:     SLAI2_HUMAN (see all proteins):
    SLAIN1

    SLAIN2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLAIN2 (see all 1665)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs711912221,2
    C--48296290(+) TCTCT-/CTGTGTC 1 -- int11Minor allele frequency- CT:0.00NA 2
    rs105725221,2
    C--48297096(+) GCCTC-/A/A   
       A
    /AAA
    AAAAA
    1 -- int11CSA 2
    rs1921073391,2
    --48341766(+) GGGTTC/TGCCTT 1 -- us2k10--------
    rs1158995451,2
    F--48341855(+) TTTTTA/CACCCT 1 -- us2k11Minor allele frequency- C:0.01WA 118
    rs1455698511,2
    --48342034(+) AAATAC/TGTTTT 1 -- us2k10--------
    rs1135723621,2
    C,F--48342046(+) TGCTAC/TGAATA 1 -- us2k11Minor allele frequency- T:0.50NA 2
    rs1499286141,2
    C--48342103(+) ACAAA-/CCCAAG 1 -- us2k10--------
    rs1486394691,2
    --48342283(+) TGCAGA/CATAAT 1 -- us2k10--------
    rs1846042401,2
    --48342352(+) GAAAAG/TAATCA 1 -- us2k10--------
    rs792534271,2
    F--48342361(+) CAGATA/GTGGCA 1 -- us2k12Minor allele frequency- G:0.10CSA WA 120

    HapMap Linkage Disequilibrium report for SLAIN2 (48343339 - 48428229 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for SLAIN2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2662770CNV Deletion23128226
    nsv528084CNV Loss19592680
    nsv509896CNV Loss20534489
    nsv470034CNV Gain18288195

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLAIN2
    DNA2.0 Custom Variant and Variant Library Synthesis for SLAIN2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610492    OMIM disorders: --

    3 diseases for SLAIN2:    
    About MalaCards
    intrahepatic cholangiocarcinoma    cholangiocarcinoma    inflammatory bowel disease


    SLAIN2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLAIN2
    Human Genome Epidemiology (HuGE) Navigator: SLAIN2 (1 document)

    Export disorders for SLAIN2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLAIN2 gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with SLAIN2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. (PubMed id 21646404)1, 2 van der Vaart B.... Akhmanova A. (J. Cell Biol. 2011)
    2. Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment. (PubMed id 20056178)1, 4 Segat L....Crovella S. (Vaccine 2010)
    3. Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene. (PubMed id 16546155)1, 3 Hirst C.E....Elefanty A.G. (Dev. Biol. 2006)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2 Nagase T.... Ohara O. (DNA Res. 2000)
    6. Quantitative study of the interactome of PKCIP involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (J. Proteome Res. 2013)
    7. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. (PubMed id 23128233)1 Jostins L....Cho J.H. (Nature 2012)
    10. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57606 HGNC: 29282 AceView: KIAA1458 Ensembl:ENSG00000109171 euGenes: HUgn57606
    ECgene: SLAIN2 H-InvDB: SLAIN2

    (According to HUGE)
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    HUGE: KIAA1458

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SLAIN2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLAIN2 gene:
    Search GeneIP for patents involving SLAIN2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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