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SKOR1 Gene

protein-coding   GIFtS: 42
GCID: GC15P068113

SKI Family Transcriptional Corepressor 1

(Previous name: Lbxcor1 homolog (mouse))
(Previous symbol: LBXCOR1)
  Search for SKOR1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
SKI Family Transcriptional Corepressor 11 2     Ladybird Homeobox Corepressor 12 3
LBXCOR11 2 3 5     FUSSEL152 3
CORL12 3 5     LBX1 Corepressor 12 3
Corepressor For LBX11 2     Lbxcor1 Homolog (Mouse)1
Functional Smad Suppressing Element 151 2     fussel-152
Transcriptional Corepressor CORL11 2     Lbxcor1 Homolog2
Functional Smad-Suppressing Element On Chromosome 152 3     Fussel-153

External Ids:    HGNC: 213261   Entrez Gene: 3905982   Ensembl: ENSG000001887797   OMIM: 6112735   UniProtKB: P845503   

Export aliases for SKOR1 gene to outside databases

Previous GC identifer: GC15P044951


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SKOR1 Gene:
SKOR1 (SKI family transcriptional corepressor 1) is a protein-coding gene. GO annotations related to this gene include nucleotide binding and SMAD binding. An important paralog of this gene is SKOR2.

UniProtKB/Swiss-Prot: SKOR1_HUMAN, P84550
Function: Acts as a transcriptional corepressor of LBX1 (By similarity). Inhibits BMP signaling




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000015.9  NC_018926.2  NT_010194.18  
Regulatory elements:
   Search for regulatory transcription factor binding sites for SKOR1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSKOR1 promoter sequence
   Search Chromatin IP Primers for SKOR1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SKOR1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q23   Ensembl cytogenetic band:  15q23   HGNC cytogenetic band: 15q23

SKOR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SKOR1 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P068113:  view genomic region     (about GC identifiers)

Start:
68,112,042 bp from pter      End:
68,126,899 bp from pter
Size:
14,858 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SKOR1_HUMAN, P84550 (See protein sequence)
Recommended Name: SKI family transcriptional corepressor 1  
Size: 965 amino acids; 99831 Da
Subunit: Interacts with LBX1 (By similarity). Interacts with SMAD1, SMAD2 and SMAD3
Secondary accessions: A6NIP4 A6NJY0 Q2VWA5
Alternative splicing: 3 isoforms:  P84550-1   P84550-2   P84550-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SKOR1: NX_P84550

Explore proteomics data for SKOR1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SKOR1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001244953.1  
    ENSEMBL proteins: 
     ENSP00000343200   ENSP00000451193   ENSP00000452361   ENSP00000369374   ENSP00000373654  

    SKOR1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for SKOR1

     
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    SKOR1 Assay Products:

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    Cloud-Clone Corp. CLIAs for SKOR1
    Search eBioscience for ELISAs for SKOR1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SKOR: SKI transcriptional corepressors

    Selected InterPro protein domains (see all 6):
     IPR009061 DNA-bd_dom_put
     IPR028762 SKOR1
     IPR023216 Tscrpt_reg_SKI_SnoN
     IPR010919 SAND_dom-like
     IPR003380 Transform_Ski

    Graphical View of Domain Structure for InterPro Entry P84550

    ProtoNet protein and cluster: P84550

    2 Blocks protein domains:
    IPB000770 SAND domain
    IPB010919 SAND-like


    UniProtKB/Swiss-Prot: SKOR1_HUMAN, P84550
    Similarity: Belongs to the SKI family


    Find genes that share domains with SKOR1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SKOR1_HUMAN, P84550
    Function: Acts as a transcriptional corepressor of LBX1 (By similarity). Inhibits BMP signaling

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0003714transcription corepressor activity IEA--
    GO:0005515protein binding ----
    GO:0046332SMAD binding IPI17292623
         
    Find genes that share ontologies with SKOR1           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SKOR1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SKOR1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SKOR1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SKOR1

    miRNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SKOR1

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SKOR1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SKOR1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SKOR1_HUMAN, P84550: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol1
    endoplasmic reticulum1
    extracellular1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus NAS17292623
    GO:0005667transcription factor complex IEA--
    GO:0005737cytoplasm IBA--
    GO:0030425dendrite IDA17292623
    GO:0043025neuronal cell body IDA17292623

    Find genes that share ontologies with SKOR1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SKOR1
    Interactions:

        Search GeneGlobe Interaction Network for SKOR1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    Selected Interacting proteins for SKOR1 (P845503 ENSP000003736544) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTBP1Q133633, ENSP000002909214I2D: score=1 STRING: ENSP00000290921
    LBX1P529543, ENSP000003592124I2D: score=1 STRING: ENSP00000359212
    TLE1Q047243, ENSP000003656824I2D: score=1 STRING: ENSP00000365682
    HDAC1Q135473, ENSP000003626494I2D: score=1 STRING: ENSP00000362649
    HIPK2Q9H2X63I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IBA--
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated NAS17292623
    GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway IBA--
    GO:0030514negative regulation of BMP signaling pathway IDA17292623

    Find genes that share ontologies with SKOR1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SKOR1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SKOR1 gene (2 alternative transcripts): 
    NM_001031807.1  NM_001258024.1  

    Unigene Cluster for SKOR1:

    SKI family transcriptional corepressor 1
    Hs.451224  [show with all ESTs]
    Unigene Representative Sequence: AY669507
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000341418 ENST00000554240 ENST00000554054 ENST00000380035 ENST00000389002(uc002aqy.1)

    miRNA
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    Search for qRT-PCR Assays for microRNAs that regulate SKOR1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SKOR1
    Predesigned siRNA for gene silencing in human, mouse, rat SKOR1
    Clone
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    OriGene clones in human, mouse for SKOR1 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SKOR1 (NM_001031807)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SKOR1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SKOR1
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SKOR1
      QuantiTect SYBR Green Assays in human, mouse, rat SKOR1
      Search QuantiFast Probe-based Assays in human, mouse, rat SKOR1

    Additional mRNA sequence: AY669507.1 

    1 DOTS entry:

    DT.101970423 

    2 AceView cDNA sequences:

    CF136193 BI831656 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SKOR1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTCTGGCCAG
    SKOR1 Expression
    About this image

    SKOR1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SKOR1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.451224

    UniProtKB/Swiss-Prot: SKOR1_HUMAN, P84550
    Tissue specificity: Present specifically in cerebellar Purkinje cells (at protein level)

        Custom PCR Arrays for SKOR1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SKOR1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SKOR1 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    15(a)
    many ↔ many
    GL343996.1(23739-34667)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.131542 Transcribed sequences 81.34(n)    BX726161.1 
    zebrafish
    (Danio rerio)
    Actinopterygii skor1a6
    skor1b6
    SKI family transcriptional corepressor 1b
    54(a)
    51(a)
    many → 1
    many → 1
    7(35289896-35296061) ENSDARG00000069030
    18(19755322-19762740) ENSDARG00000062448
    fruit fly
    (Drosophila melanogaster)
    Insecta CG110936
    --
    28(a)
    1 → many
    4(982967-999048)
            Species with no ortholog for SKOR1

    ENSEMBL Gene Tree for SKOR1 (if available)
    TreeFam Gene Tree for SKOR1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SKOR1 gene
    SKOR22  SKI2  SKIL2  
    1 SIMAP similar gene for SKOR1 using alignment to 3 protein entries:     SKOR1_HUMAN (see all proteins):
    SKI

    Find genes that share paralogs with SKOR1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SKOR1 (see all 323)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1851393311,2
    --68110111(+) TGAAAC/TTCCAT 1 -- us2k10--------
    rs1394193051,2
    C--68110135(+) ACAAAA/CATCAG 1 -- us2k10--------
    rs1911305481,2
    --68110292(+) TTTCAA/GAAAAT 1 -- us2k10--------
    rs286882851,2
    C,F--68110297(+) AAAAAT/CAAAAA 1 -- us2k1 tfbs36Minor allele frequency- C:0.30WA NA EA 364
    rs1832706531,2
    --68110349(+) AATACA/GTTACA 1 -- us2k10--------
    rs556969471,2
    C--68110611(+) ACCTTC/TTCTTG 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1389572421,2
    C--68110695(+) GGGCT-/CACAACC 1 -- us2k10--------
    rs9224931,2
    C,F,H--68110748(+) TACCTA/GCTAAG 1 -- us2k117Minor allele frequency- G:0.08NS EA NA CSA 2224
    rs1451562411,2
    C--68110767(+) CCTGGA/GTATGC 1 -- us2k10--------
    rs772716511,2
    C--68110793(+) ATTCCC/TGTGGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SKOR1 (68112042 - 68126899 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SKOR1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv1578CNV Insertion18451855
    nsv827375CNV Gain20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SKOR1
    DNA2.0 Custom Variant and Variant Library Synthesis for SKOR1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611273    OMIM disorders: --


    Find genes that share disorders with SKOR1           About GenesLikeMe

    Human Genome Epidemiology (HuGE) Navigator: SKOR1 (0 documents)

    Export disorders for SKOR1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SKOR1 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with SKOR1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Corl1, a novel neuronal lineage-specific transcriptional corepressor for the homeodomain transcription factor Lbx1. (PubMed id 15528197)1, 3, 9 Mizuhara E....Ono Y. (J. Biol. Chem. 2005)
    2. Fussel-15, a novel Ski/Sno homolog protein, antagonizes BMP signaling. (PubMed id 17292623)1, 2 Arndt S.... Bosserhoff A.-K. (Mol. Cell. Neurosci. 2007)
    3. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)1, 2 Zody M.C....Nusbaum C. (Nature 2006)
    4. Fussel-15, a new player in wound healing, is deregulated in keloid and localized scleroderma. (PubMed id 21641385)1 Arndt S....Bosserhoff A.K. (Am. J. Pathol. 2011)
    5. Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1. (PubMed id 21779176)1 Winkelmann J....Meitinger T. (PLoS Genet. 2011)
    6. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. (PubMed id 20935630)1 Speliotes E.K....Loos R.J. (Nat. Genet. 2010)
    7. Association of intronic variants of the BTBD9 gene with Tourette syndrome. (PubMed id 19822783)1 RiviA"re J.B....Rouleau G.A. (Arch. Neurol. 2009)
    8. Replication of restless legs syndrome loci in three European populations. (PubMed id 19279021)1 Kemlink D....Winkelmann J. (J. Med. Genet. 2009)
    9. Genetics of restless legs syndrome. (PubMed id 18541116)1 Winkelmann J. (Curr Neurol Neurosci Rep 2008)
    10. Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions. (PubMed id 17637780)1 Winkelmann J....Meitinger T. (Nat. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 390598 HGNC: 21326 AceView: LOC390598 Ensembl:ENSG00000188779 euGenes: HUgn390598
    ECgene: SKOR1 H-InvDB: SKOR1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SKOR1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SKOR1 gene:
    Search GeneIP for patents involving SKOR1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SKOR1  
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     OriGene Custom Antibody Services for SKOR1   OriGene Custom Protein Services for SKOR1  

     
     
     Block miRNA regulation of human, mouse, rat SKOR1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SKOR1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SKOR1 Predesigned siRNA for gene silencing in human, mouse, rat SKOR1
     Search QuantiFast Probe-based Assays in human, mouse, rat SKOR1 QuantiTect SYBR Green Assays in human, mouse, rat SKOR1
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     Search Addgene for plasmids for SKOR1
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