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Aliases for SKINTL Gene

Aliases for SKINTL Gene

  • Skint-Like, Pseudogene 2 3
  • SKINT1 3 4
  • Skint-Like Pseudogene 4
  • Skint-1 4
  • SKINTP 3
  • BTN12 3

External Ids for SKINTL Gene

Previous HGNC Symbols for SKINTL Gene

  • SKINTP

Previous GeneCards Identifiers for SKINTL Gene

  • GC01M048400
  • GC01M048567
  • GC01M046684

Summaries for SKINTL Gene

GeneCards Summary for SKINTL Gene

SKINTL (Skint-Like, Pseudogene) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SKINTL Gene

Genomics for SKINTL Gene

Regulatory Elements for SKINTL Gene

Genomic Location for SKINTL Gene

Start:
48,096,092 bp from pter
End:
48,182,428 bp from pter
Size:
86,337 bases
Orientation:
Minus strand

Genomic View for SKINTL Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SKINTL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SKINTL Gene

Proteins for SKINTL Gene

  • Protein details for SKINTL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MVG2-SKIT1_HUMAN
    Recommended name:
    Putative selection and upkeep of intraepithelial T-cells protein 1 homolog
    Protein Accession:
    A8MVG2
    Secondary Accessions:

    Protein attributes for SKINTL Gene

    Size:
    218 amino acids
    Molecular mass:
    25405 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SKINTL Gene

Proteomics data for SKINTL Gene at MOPED

Post-translational modifications for SKINTL Gene

  • Glycosylation at Asn53 and Asn155

No data available for DME Specific Peptides for SKINTL Gene

Domains for SKINTL Gene

Gene Families for SKINTL Gene

HGNC:
  • BTN :Butyrophilins

Protein Domains for SKINTL Gene

Graphical View of Domain Structure for InterPro Entry

A8MVG2

UniProtKB/Swiss-Prot:

SKIT1_HUMAN :
  • A8MVG2
Domain:
  • Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Family:
  • Belongs to the SKINT family.
genes like me logo Genes that share domains with SKINTL: view

No data available for Suggested Antigen Peptide Sequences for SKINTL Gene

Function for SKINTL Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SKINTL Gene

Localization for SKINTL Gene

Subcellular locations from UniProtKB/Swiss-Prot for SKINTL Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SKINTL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SKINTL: view

No data available for Subcellular locations from COMPARTMENTS for SKINTL Gene

Pathways for SKINTL Gene

SuperPathways for SKINTL Gene

No Data Available

Interacting Proteins for SKINTL Gene

Gene Ontology (GO) - Biological Process for SKINTL Gene

None

No data available for Pathways by source for SKINTL Gene

Transcripts for SKINTL Gene

mRNA/cDNA for SKINTL Gene

(1) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SKINTL Gene

Skint-like, pseudogene:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SKINTL

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SKINTL Gene

No ASD Table

Relevant External Links for SKINTL Gene

GeneLoc Exon Structure for
SKINTL
ECgene alternative splicing isoforms for
SKINTL

Expression for SKINTL Gene

mRNA expression in normal human tissues for SKINTL Gene

SOURCE GeneReport for Unigene cluster for SKINTL Gene Hs.585393

genes like me logo Genes that share expressions with SKINTL: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for SKINTL Gene

Orthologs for SKINTL Gene

Evolution for SKINTL Gene

ENSEMBL:
Gene Tree for SKINTL (if available)
TreeFam:
Gene Tree for SKINTL (if available)

No data available for Orthologs for SKINTL Gene

Paralogs for SKINTL Gene

Selected SIMAP similar genes for SKINTL Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SKINTL: view

No data available for Paralogs for SKINTL Gene

Variants for SKINTL Gene

Sequence variations from dbSNP and Humsavar for SKINTL Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs127723 -- 48,165,993(-) CTACA(A/G)TCTAT intron-variant
rs183337 -- 48,140,727(-) tacag(G/T)gttac intron-variant
rs188516 -- 48,140,696(-) tgtag(G/T)gaata intron-variant
rs190047 -- 48,174,418(-) gcctg(G/T)cgggg intron-variant
rs191941 -- 48,140,718(-) actca(A/G)agccc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SKINTL Gene

Variant ID Type Subtype PubMed ID
nsv871563 CNV Loss 21882294
nsv871053 CNV Gain 21882294

Relevant External Links for SKINTL Gene

HapMap Linkage Disequilibrium report
SKINTL

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SKINTL Gene

Disorders for SKINTL Gene

No disorders were found for SKINTL Gene.

No data available for UniProtKB/Swiss-Prot for SKINTL Gene

Publications for SKINTL Gene

  1. Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gammadelta T cells. (PMID: 18408721) Boyden L.M. … Lifton R.P. (Nat. Genet. 2008) 2 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4

Products for SKINTL Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate SKINTL
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SKINTL
    • Block miRNA regulation of SKINTL using miScript Target Protectors

    Sources for SKINTL Gene

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