SKIDA1 Gene
protein-coding GIFtS: 35
GCID: GC10M021802
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SKI/DACH domain containing 1(Previous name: chromosome 10 open reading frame 140 )
(Previous symbol: C10orf140)
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Aliases
for SKIDA1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SKI/DACH Domain Containing 11 2 | | Chromosome 10 Open Reading Frame 1401 | | C10orf1401 2 3 | | DLN-12 | | Protein DLN-12 3 | | SKI/DACH Domain-Containing Protein 12 | | FLJ451871 | | DLN13 |
Export aliases for SKIDA1 gene to outside databases |
Summaries
for SKIDA1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for SKIDA1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_008705.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for SKIDA1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SKIDA1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SKIDA1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10p12.31 Ensembl cytogenetic band: 10p12.31 HGNC cytogenetic band: 10p12.31SKIDA1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10M021802: view genomic region
(about GC identifiers)
Start:
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21,802,407 bp from pter |
End:
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21,814,611 bp from pter |
Size:
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12,205 bases |
Orientation:
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minus strand |
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Proteins
for SKIDA1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SKDA1_HUMAN, Q1XH10 (See
protein sequence)Recommended Name: SKI/DACH domain-containing protein 1 Size: 827 amino acids; 90476 Da
Secondary accessions: B1ANA5 Q6ZMX4 Q8N3C3Explore the universe of human proteins at neXtProt for SKIDA1: NX_Q1XH10
Post-translational modifications:
View modification sites using PhosphoSitePlus2 (DLN1)View neXtProt modification sites for NX_Q1XH10
SKIDA1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_997254.3
ENSEMBL proteins: ENSP00000410041 ENSP00000442432
Human Recombinant Protein Products for SKIDA1:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
SKIDA1 for ontologies About GeneDecksing
SKIDA1 Antibody Products:
Assay Products for SKIDA1: |
Protein
Domains /
Families
for SKIDA1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SKIDA1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q1XH10ProtoNet protein and cluster: Q1XH10 UniProtKB/Swiss-Prot: SKDA1_HUMAN, Q1XH10Similarity: Belongs to the DACH/dachshund family |
Function
for SKIDA1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000166 | nucleotide binding |
IEA | -- |
SKIDA1 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SKIDA1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SKIDA1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for SKIDA1 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SKIDA1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SKIDA1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SKIDA1 |
|
Pathways & Interactions
for SKIDA1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SKIDA1
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for SKIDA1 (ENSP000004100414) via UniProtKB, MINT, STRING, and/or I2DAbout this table
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Drugs & Compounds
for SKIDA1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SKIDA1
Search CenterWatch for drugs/clinical trials and news about SKIDA1 / SKDA1
|
Transcripts
for SKIDA1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SKIDA1 gene: NM_207371.3 Unigene Cluster for SKIDA1: SKI/DACH domain containing 1 Hs.350848 [show with all ESTs]Unigene Representative Sequence: NM_2073713 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000449193(uc009xkd.3) ENST00000487107 ENST00000444772
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SKIDA1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SKIDA1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for SKIDA1 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SKIDA1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SKIDA1 |
Additional cDNA sequence: AB234866.1 AK055656.1 AK127130.1 AK131456.1 AK299717.1 AL834446.1 BC142633.1 3 DOTS entries: DT.101974978 DT.40257672 DT.75153595 7 AceView cDNA sequences: NM_207371 AL834446 AK131456 BE250228 AA723015 AI363206 BI497298
GeneLoc Exon Structure
|
Expression
for SKIDA1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
See SKIDA1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SKIDA1
SOURCE GeneReport for Unigene cluster: Hs.350848
SABiosciences Custom PCR Arrays for SKIDA1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SKIDA1
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat SKIDA1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SKIDA1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SKIDA1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SKIDA1 |
Orthologs
for SKIDA1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for SKIDA1 gene from 5/12 species (see all 12) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Skida11 , 5 |
RIKEN cDNA 2810030E01 gene5
SKI/DACH domain containing 11 |
93.24(n)1
93.58(a)1 |
|
2 (12.83 cM)5
726681 NM_028317.21 NP_082593.21
180406765 |
chicken
(Gallus gallus) |
Aves |
SKIDA11 |
SKI/DACH domain containing 1 |
75.41(n)
71.66(a) |
|
420510 XM_418611.3 XP_418611.3 |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
48(a) |
1 ↔ 1 |
6(16717694-16720269) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.93272 |
Transcribed sequence with weak similarity to protein more |
79.05(n) |
|
BX698576.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
AL722971.12 |
-- |
77.44(n) |
|
AL722971.1 |
ENSEMBL Gene Tree for SKIDA1 (if available)
TreeFam Gene Tree for SKIDA1 (if available) |
Paralogs
for SKIDA1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SKIDA1 gene
- C17orf962
SKIDA1 for paralogs About GeneDecksing
|
Genomic Variants
for SKIDA1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: SKDA1_HUMAN, Q1XH10Polymorphism: The poly-Ala region of SKIDA1 is highly polymorphic and the number of Ala can vary
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SKIDA1 (21802407 - 21814611 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SKIDA1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SKIDA1 |
|
Disorders
/ Diseases
for SKIDA1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for SKIDA1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SKIDA1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SKIDA1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)2 Deloukas P.... Rogers J. (2004)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
- Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. (PubMed id 7829101)1 Robertson N.G....Morton C.C. (1994)
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External Searches for SKIDA1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing SKIDA1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SKIDA1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SKIDA1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SKIDA1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SKIDA1 gene:
Search GeneIP for patents involving SKIDA1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SKIDA1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SKIDA1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SKIDA1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SKIDA1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SKIDA1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SKIDA1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SKIDA1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SKIDA1 | | OriGene Custom Protein Services for SKIDA1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SKIDA1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SKIDA1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SKIDA1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SKIDA1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SKIDA1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SKIDA1 |
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 |  |  |  | |
| | | | Search Tocris compounds for SKIDA1 |
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 | | | SKIDA1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SKIDA1 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for SKIDA1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SKIDA1 |
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