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Aliases for SKIDA1 Gene

Aliases for SKIDA1 Gene

  • SKI/DACH Domain Containing 1 2 3
  • Protein DLN-1 3 4
  • C10orf140 3 4
  • Chromosome 10 Open Reading Frame 140 2
  • SKI/DACH Domain-Containing Protein 1 3
  • DLN-1 3
  • DLN1 4

External Ids for SKIDA1 Gene

Previous HGNC Symbols for SKIDA1 Gene

  • C10orf140

Previous GeneCards Identifiers for SKIDA1 Gene

  • GC10M021802

Summaries for SKIDA1 Gene

GeneCards Summary for SKIDA1 Gene

SKIDA1 (SKI/DACH Domain Containing 1) is a Protein Coding gene. GO annotations related to this gene include nucleotide binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SKIDA1 Gene

Genomics for SKIDA1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SKIDA1 Gene

Start:
21,513,478 bp from pter
End:
21,526,308 bp from pter
Size:
12,831 bases
Orientation:
Minus strand

Genomic View for SKIDA1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SKIDA1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SKIDA1 Gene

No data available for Regulatory Elements for SKIDA1 Gene

Proteins for SKIDA1 Gene

  • Protein details for SKIDA1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q1XH10-SKDA1_HUMAN
    Recommended name:
    SKI/DACH domain-containing protein 1
    Protein Accession:
    Q1XH10
    Secondary Accessions:
    • B1ANA5
    • Q6ZMX4
    • Q8N3C3

    Protein attributes for SKIDA1 Gene

    Size:
    827 amino acids
    Molecular mass:
    90476 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SKIDA1 Gene

Proteomics data for SKIDA1 Gene at MOPED

Post-translational modifications for SKIDA1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SKIDA1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SKIDA1 Gene

Domains for SKIDA1 Gene

Protein Domains for SKIDA1 Gene

Graphical View of Domain Structure for InterPro Entry

Q1XH10

UniProtKB/Swiss-Prot:

SKDA1_HUMAN :
  • Q1XH10
Family:
  • Belongs to the DACH/dachshund family.
genes like me logo Genes that share domains with SKIDA1: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for SKIDA1 Gene

Function for SKIDA1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SKIDA1 Gene

Localization for SKIDA1 Gene

Gene Ontology (GO) - Cellular Components for SKIDA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with SKIDA1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for SKIDA1 Gene

Pathways for SKIDA1 Gene

SuperPathways for SKIDA1 Gene

No Data Available

Interacting Proteins for SKIDA1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000410041%0d%0a9606.ENSP00000385269%0d%0a9606.ENSP00000316578%0d%0a
Selected Interacting proteins: ENSP00000410041 for SKIDA1 Gene via STRING

Gene Ontology (GO) - Biological Process for SKIDA1 Gene

None

No data available for Pathways by source for SKIDA1 Gene

Transcripts for SKIDA1 Gene

mRNA/cDNA for SKIDA1 Gene

(7) Additional mRNA sequences :
(12) REFSEQ mRNAs :
(7) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SKIDA1 Gene

SKI/DACH domain containing 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SKIDA1

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for SKIDA1
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SKIDA1 Gene

No ASD Table

Relevant External Links for SKIDA1 Gene

GeneLoc Exon Structure for
SKIDA1
ECgene alternative splicing isoforms for
SKIDA1

Expression for SKIDA1 Gene

mRNA expression in normal human tissues for SKIDA1 Gene

SOURCE GeneReport for Unigene cluster for SKIDA1 Gene Hs.350848

genes like me logo Genes that share expressions with SKIDA1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for SKIDA1 Gene

Orthologs for SKIDA1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SKIDA1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SKIDA1 35
  • 99.42 (n)
  • 99.14 (a)
SKIDA1 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SKIDA1 36
  • 76 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SKIDA1 35
  • 96.08 (n)
  • 95.59 (a)
SKIDA1 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Skida1 35
  • 92.06 (n)
  • 92.36 (a)
Skida1 16
Skida1 36
  • 92 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SKIDA1 36
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SKIDA1 36
  • 78 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Skida1 35
  • 94.06 (n)
  • 91.27 (a)
chicken
(Gallus gallus)
Aves C2H10ORF140 35
  • 77.38 (n)
  • 74.02 (a)
SKIDA1 36
  • 74 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 49 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.9327 35
zebrafish
(Danio rerio)
Actinopterygii SKIDA1 36
  • 42 (a)
OneToOne
Species with no ortholog for SKIDA1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SKIDA1 Gene

ENSEMBL:
Gene Tree for SKIDA1 (if available)
TreeFam:
Gene Tree for SKIDA1 (if available)

Paralogs for SKIDA1 Gene

No data available for Paralogs for SKIDA1 Gene

Variants for SKIDA1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for SKIDA1 Gene

Q1XH10-SKDA1_HUMAN
The poly-Ala region of SKIDA1 is highly polymorphic and the number of Ala can vary

Sequence variations from dbSNP and Humsavar for SKIDA1 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs946711 -- 21,517,903(+) TCCTC(A/C)GCCAG utr-variant-5-prime
rs3758595 -- 21,523,882(-) TCCCG(C/G)TTTTT intron-variant
rs4083949 -- 21,521,689(+) AATTA(A/C)ATGTG intron-variant
rs7072980 -- 21,517,392(+) CGGCT(C/T)CGCTC missense, reference
rs7079672 -- 21,513,725(+) AAACA(C/G)AAGTT utr-variant-3-prime

Relevant External Links for SKIDA1 Gene

HapMap Linkage Disequilibrium report
SKIDA1

No data available for Structural Variations from Database of Genomic Variants (DGV) for SKIDA1 Gene

Disorders for SKIDA1 Gene

No disorders were found for SKIDA1 Gene.

No data available for UniProtKB/Swiss-Prot for SKIDA1 Gene

Publications for SKIDA1 Gene

  1. Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. (PMID: 7829101) Robertson N.G. … Morton C.C. (Genomics 1994) 3
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  4. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 3
  5. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3

Products for SKIDA1 Gene

Sources for SKIDA1 Gene

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