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Aliases for SKIDA1 Gene

Aliases for SKIDA1 Gene

  • SKI/DACH Domain Containing 1 2 3
  • Protein DLN-1 3 4
  • C10orf140 3 4
  • Chromosome 10 Open Reading Frame 140 2
  • DLN-1 3
  • DLN1 4

External Ids for SKIDA1 Gene

Previous HGNC Symbols for SKIDA1 Gene

  • C10orf140

Previous GeneCards Identifiers for SKIDA1 Gene

  • GC10M021802

Summaries for SKIDA1 Gene

GeneCards Summary for SKIDA1 Gene

SKIDA1 (SKI/DACH Domain Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SKIDA1 Gene

Genomics for SKIDA1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SKIDA1 Gene

21,510,754 bp from pter
21,527,188 bp from pter
16,435 bases
Minus strand

Genomic View for SKIDA1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SKIDA1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SKIDA1 Gene

No data available for Regulatory Elements for SKIDA1 Gene

Proteins for SKIDA1 Gene

  • Protein details for SKIDA1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    SKI/DACH domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • B1ANA5
    • Q6ZMX4
    • Q8N3C3

    Protein attributes for SKIDA1 Gene

    827 amino acids
    Molecular mass:
    90476 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SKIDA1 Gene

Proteomics data for SKIDA1 Gene at MOPED

Post-translational modifications for SKIDA1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SKIDA1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SKIDA1 Gene

Domains & Families for SKIDA1 Gene

Protein Domains for SKIDA1 Gene

Suggested Antigen Peptide Sequences for SKIDA1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the DACH/dachshund family.
  • Belongs to the DACH/dachshund family.
genes like me logo Genes that share domains with SKIDA1: view

No data available for Gene Families for SKIDA1 Gene

Function for SKIDA1 Gene

Phenotypes for SKIDA1 Gene

genes like me logo Genes that share phenotypes with SKIDA1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SKIDA1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for SKIDA1 Gene

Localization for SKIDA1 Gene

Subcellular locations from

Jensen Localization Image for SKIDA1 Gene COMPARTMENTS Subcellular localization image for SKIDA1 gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SKIDA1 Gene

Pathways & Interactions for SKIDA1 Gene

SuperPathways for SKIDA1 Gene

No Data Available

Interacting Proteins for SKIDA1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000410041 for SKIDA1 Gene via STRING

Gene Ontology (GO) - Biological Process for SKIDA1 Gene


No data available for Pathways by source and SIGNOR curated interactions for SKIDA1 Gene

Drugs & Compounds for SKIDA1 Gene

No Compound Related Data Available

Transcripts for SKIDA1 Gene

mRNA/cDNA for SKIDA1 Gene

(12) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SKIDA1 Gene

SKI/DACH domain containing 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SKIDA1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SKIDA1 Gene

No ASD Table

Relevant External Links for SKIDA1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SKIDA1 Gene

mRNA expression in normal human tissues for SKIDA1 Gene

SOURCE GeneReport for Unigene cluster for SKIDA1 Gene Hs.350848

genes like me logo Genes that share expression patterns with SKIDA1: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SKIDA1 Gene

Orthologs for SKIDA1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SKIDA1 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia SKIDA1 35
  • 96.08 (n)
  • 95.59 (a)
  • 89 (a)
(Mus musculus)
Mammalia Skida1 35
  • 92.06 (n)
  • 92.36 (a)
Skida1 16
Skida1 36
  • 92 (a)
(Pan troglodytes)
Mammalia SKIDA1 35
  • 99.42 (n)
  • 99.14 (a)
  • 98 (a)
(Rattus norvegicus)
Mammalia Skida1 35
  • 94.06 (n)
  • 91.27 (a)
(Bos Taurus)
Mammalia SKIDA1 36
  • 76 (a)
(Monodelphis domestica)
Mammalia SKIDA1 36
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia SKIDA1 36
  • 78 (a)
(Gallus gallus)
Aves C2H10ORF140 35
  • 77.38 (n)
  • 74.02 (a)
  • 74 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 49 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.9327 35
(Danio rerio)
Actinopterygii SKIDA1 36
  • 42 (a)
Species with no ortholog for SKIDA1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SKIDA1 Gene

Gene Tree for SKIDA1 (if available)
Gene Tree for SKIDA1 (if available)

Paralogs for SKIDA1 Gene

No data available for Paralogs for SKIDA1 Gene

Variants for SKIDA1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for SKIDA1 Gene

The poly-Ala region of SKIDA1 is highly polymorphic and the number of Ala can vary

Sequence variations from dbSNP and Humsavar for SKIDA1 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs946711 -- 21,517,903(+) TCCTC(A/C)GCCAG utr-variant-5-prime
rs3758595 -- 21,523,882(-) TCCCG(C/G)TTTTT intron-variant, upstream-variant-2KB
rs4083949 -- 21,521,689(+) AATTA(A/C)ATGTG intron-variant
rs7072980 -- 21,517,392(+) CGGCT(C/T)CGCTC missense, reference
rs7079672 -- 21,513,725(+) AAACA(C/G)AAGTT utr-variant-3-prime

Variation tolerance for SKIDA1 Gene

Residual Variation Intolerance Score: 52% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.36; 63.39% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SKIDA1 Gene

HapMap Linkage Disequilibrium report

No data available for Structural Variations from Database of Genomic Variants (DGV) for SKIDA1 Gene

Disorders for SKIDA1 Gene

Relevant External Links for SKIDA1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with SKIDA1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SKIDA1 Gene

Publications for SKIDA1 Gene

  1. GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. (PMID: 23535730) Pharoah P.D. … Sellers T.A. (Nat. Genet. 2013) 67
  2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 67
  3. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 67
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 67
  5. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 67

Products for SKIDA1 Gene

Sources for SKIDA1 Gene

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