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SKI Gene

protein-coding GIFtS: 66

GC01P002173

v-ski sarcoma viral oncogene homolog (avian)
(Previous name: v-ski avian sarcoma viral oncogene homolog )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
C-ski ^³
OTTHUMP00000001507 ^²
SKV ^²

Descriptions
Avian sarcoma viral (v-ski) oncogene homolog ^²
ski oncoprotein ^²
v-ski avian sarcoma viral oncogene homolog ^¹, ²
v-ski sarcoma viral oncogene homolog ^²
v-ski sarcoma viral oncogene homolog (avian) ^²

External Ids
HGNC: 10896¹
Entrez Gene: 6497²
UniProtKB: P12755³
Ensembl: ENSG00000157933⁷

Search outside databases for aliases for SKI gene

Previous GC identifers: GC01P001715 GC01P9M0086

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: SKI_HUMAN, P12755

Function: May play a role in terminal differentiation of skeletal muscle cells but not in the

determination of cells to the myogenic lineage

Gene Wiki entry for SKI (SKI_protein)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the SKI gene

Entrez Gene cytogenetic band: 1q22-q24 Ensembl cytogenetic band: 1p36.33 HGNC cytogenetic band: 1q22-q24

SKI Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P002173: (about GC identifiers)

Start:	2,149,994 bp from pter
End:	2,229,316 bp from pter
Size:	79,323 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000001.9 NT_004350.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: SKI_HUMAN, P12755 (See protein sequence)

Recommended Name: Ski oncogene

Size: 728 amino acids; 80005 Da

Subunit: Interacts with SMAD2, SMAD3 and SMAD4. Interacts with HIPK2. Part of a complex with HIPK2

and SMAD1/2/3

Subcellular location: Nucleus

PDB structure from and Proteopedia :

1MR1 (3D)

1SBX (3D)

Secondary accessions: Q5SYT7

REFSEQ proteins: NP_003027.1

ENSEMBL proteins:

ENSP00000367797

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (SKI)
	Browse Abnova for Human Recombinant Proteins

OriGene Purified Recombinant Human Protein: SKI

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	NAS	--
GO:0005654	nucleoplasm	EXP	10549282 11121043

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Antibodies for SKI:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of SKI
	Sigma-Aldrich Antibodies for SKI
	R&D Systems Antibodies for SKI
	Antibodies from Abcam (SKI), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for SKI

Assays for SKI:

	Browse Invitrogen for biochemical assays
	Millipore Kits and Assays for the Analysis of SKI
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P12755

ProtoNet protein and cluster: P12755

3 Blocks protein families:

IPB000770 SAND domain

IPB003380 Transforming protein Ski

IPB010919 SAND-like

UniProtKB/Swiss-Prot: SKI_HUMAN, P12755

Similarity: Belongs to the SKI family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SKI)
		Millipore RNAi Products for the Analysis of SKI Gene knock-down
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003036

Applied Biosystems Silencer® siRNAs for SKI

Sigma-Aldrich siRNA for SKI

Sigma-Aldrich shRNA for SKI

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_003036
Myc/DDK tagged cDNA clone in CMV expression vector: NM_003036
untagged cDNA clone in CMV expression vector: NM_003036

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_003036

UniProtKB/Swiss-Prot: SKI_HUMAN, P12755

Function: May play a role in terminal differentiation of skeletal muscle cells but not in the

determination of cells to the myogenic lineage

Genatlas biochemistry entry for SKI:

avian sarcoma viral (v-ski) oncogene homolog

12 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Ski):

	cellular	craniofacial	embryogenesis	growth/size
lethality-prenatal/perinatal	limbs/digits/tail	muscle	nervous system	skeleton
tumorigenesis	vision/eye

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0005515	protein binding	IPI	14525983

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for SKI

5/25 Interacting proteins for SKI (ENSP00000367797³ P12755^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 25 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
NCOR1	O75376¹	STRING (score=.988) EBI-347281, EBI-347233
SIN3A	Q96ST3¹	STRING (score=.991) EBI-347281, EBI-347218
SMAD3	P84022¹^,²	STRING (score=.999) EBI-347281, EBI-347161 MINT-16378 MINT-17964 MINT-16379 EBI-347281, EBI-347161 MINT-16378 MINT-17964 MINT-16379
SMAD4	Q13485¹^,²	STRING (score=.999) EBI-347281, EBI-347263 MINT-61954 EBI-347281, EBI-347263 MINT-61954
SMAD3	P84022¹^,²	STRING (score=.999) EBI-347281, EBI-347161 MINT-16378 MINT-17964 MINT-16379 EBI-347281, EBI-347161 MINT-16378 MINT-17964 MINT-16379

About this table

2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0030154	cell differentiation	NAS	--
GO:0030509	BMP signaling pathway	EXP	15621726

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for SKI
2 Novoseek chemical compound relationships for SKI gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
tgf beta1	39.28	1	16871886 (1)
leucine	25.55	2	7929440 (1), 9927733 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SKI)
		Millipore RNAi Products for the Analysis of SKI Gene knock-down
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003036

Sigma-Aldrich siRNA for SKI

Sigma-Aldrich shRNA for SKI

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_003036

REFSEQ mRNAs for SKI gene:

NM_003036.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_003036

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_003036
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_003036
                                 untagged cDNA clone in CMV expression vector: NM_003036

Additional cDNA sequence:

AK309515.1 X15218.1

6 DOTS entries:

DT.445410 DT.100750103 DT.121455724 DT.121455848 DT.121455772 DT.95333060

24/121 AceView cDNA sequences (see all 121 ):

CK821024 BF109460 BF924336 BQ888578 BM555193 CD672209 AI751723 AI282809

BM760913 AI378676 X15218 BU189280 AW007133 NM_003036 AU184930 Z38298

AL134997 AI469036 CD672208 BE882804 BU182699 BM665239 BE394343 BM728747

highest scoring ESTs for SKI:

X15218 AA810956 AA969049 AI291792 AI432483 AI751723 AI819231 AI824553 AL134997 AW136188

Unigene Cluster for SKI:

V-ski sarcoma viral oncogene homolog (avian)

Hs.663133 [show with all ESTs]

Unigene Representative Sequence: NM_003036

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for SKI

ExUns:	1	^	2a	·	2b	^	3	^	4a	·	4b	·	4c	^	5	^	6	^	7a	·	7b
SP1:			-
SP2:
SP3:

About this scheme

ECgene alternative splicing isoforms for SKI

1 Ensembl transcript including schematic representation:

ENST00000378536

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

SKI expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for SKI

¹ / ² / ³

8 probe-sets matching SKI gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
52776_at²^{, 3}	U95-B	1	1.00	1.00	0.08	0.99	AI925357	0.80	0.80	0.80	1
78059_at²^{, 3}	U95-E	1	1.00	1.00	0.29	1.85	AI432483	0.80	1.00	0.91	1
41499_at²^{, 3}	U95-A	1	1.00	1.00	0.44	0.69	X15218	1.00	1.00	1.00	1
1918_at²^{, 3}	U95-A	1	1.00	1.00	0.24	0.50	X15218	1.00	1.00	1.00	1
204270_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI568728	0.60	0.75	0.68	1
229265_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AA927480	0.40	1.00	0.76	1
204270_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
229265_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGACCCCCTC

SOURCE GeneReport for Unigene cluster: Hs.663133

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for SKI gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	SKI¹	--	v-ski sarcoma viral oncogene homolog (avian)	89.81(n) 93.39(a)	489610 XM_546730.2 XP_546730.2
cow (Bos taurus)	SKI¹	--	v-ski sarcoma viral oncogene homolog (avian)	89.34(n) 90.2(a)	506127 XM_582529.3 XP_582529.3
mouse (Mus musculus)	Ski^{1, 5}	4 (78.90 cM)⁵	ski sarcoma viral oncogene homolog (avian)^{1, 5}	88.81(n)¹ 93.4(a)¹	20481¹ NM_011385.2¹ NP_035515.2¹ AA062172⁵ AA589460⁵ (see all 25)
chicken (Gallus gallus)	SKI¹	--	v-ski sarcoma viral oncogene homolog (avian)	75.96(n) 83.64(a)	428181 NM_001039318.1 NP_001034407.1
zebrafish (Danio rerio)	skia²	--	nuclear oncoprotein skia	80.2(n)	30101 NM_130935.1

About this table Species with no ortholog for SKI

ENSEMBL Gene Tree for SKI

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for SKI gene

ENSG00000215474² SKIL² LBXCOR1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/465 NCBI SNPs in SKI are shown (see all 465 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 182)

AB	SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs2843157^1,2	C,F,H	2230243(-)	`GAGCCG/AAAGTG`	1	--	ut3¹ ese³		8	EU EA WA NA	780
	rs2173049^1,2	C,F,H	2229866(+)	`CAACAC/TGCAGA`	1	--	ut3¹ ese³		3	EU EA	298
	rs3765931^1,2	F,H	2229444(+)	`GTTACG/AGTATT`	1	--	ut3¹		4	EA EU	1532
--	rs12403174^1,2	H	2225598(+)	`cacctC/Gctcct`	1	S/C	mis¹ trp³		4	EU EA WA	404
	rs2230008^1,2	F	2228097(+)	`CGACAA/TCGCGG`	1	--	ut3¹ ese³		1	MN	18
	rs2132303^1,2	A,C,F,H,O	2213118(+)	`AGCGCC/TAAAGT`	1	--	int¹		15	NA EU EA WA	1398
	rs2017143^1,2	A,C,F,H,O	2210509(+)	`TGAGCT/CTCTCT`	1	--	int¹		13	EU EA WA NA MN	1256
	rs1713712^1,2	A,C,F,H,O	2166021(+)	`TGTAAC/TTTGTG`	1	--	int¹		4	EA WA MN	482
	rs260513^1,2	A,C,F,H,O	2170384(-)	`TCGACC/TGCATC`	1	--	int¹		14	EA NA MN EU WA	928
--	rs260509^1,2	A,C,F,H,O	2176845(+)	`GTGCCA/GCTCTG`	1	--	int¹		4	EU EA WA	416

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HapMap Linkage Disequilibrium images for SKI (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 164780

8 Novoseek disease relationships for SKI gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
leukemogenesis	45.35	2	17621263 (1)
metastatic melanoma	36.82	3	12793438 (1), 15986136 (1), 11719430 (1)
tumors	24.49	28	15986136 (3), 18451154 (3), 14583455 (2), 11781823 (2) (see all 17)
melanoma	22.81	30	14583455 (6), 18782659 (5), 11719430 (4), 12793438 (3) (see all 5)
cancer	15.96	8	18451154 (2), 10485843 (1), 19114989 (1), 19096149 (1) (see all 5)
pancreatic cancer	7.60	3	17592292 (3)
carcinoma	0.00	1	19096149 (1)
leukemia	0.00	2	15542823 (1), 17621263 (1)

About this table

Human Gene Mutation Database: SKI
Genetic Association Database: SKI
Human Genome Epidemiology Navigator: SKI (3 documents)
Tumor Gene Database: SKI

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/103 PubMed articles for SKI gene (see all 103 ):

Isolation of human cDNA clones of ski and the ski-related gene, sno. (PubMed id 2762147)^{2, 3, 4} Nomura N.... Ishizaki R. (1989)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{3, 4} Gregory S.G.... Bentley D.R. (2006)
Medical sequencing of candidate genes for nonsyndromic cleft lip and palate. (PubMed id 16327884)^{3, 6} Vieira A.R....Murray J.C. (2005)
Genetic variation in the proto-oncogene SKI and risk for orofacial clefting. (PubMed id 16054854)^{3, 6} Lu W....Finnell R.H. (2005)
Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein- induced transcriptional activation. (PubMed id 12874272)^{3, 4} Harada J....Ishii S. (2003)
The Ski oncoprotein is upregulated and localized at the centrosomes and mitotic spindle during mitosis. (PubMed id 15806149)^{1, 3} Marcelain K. and Hayman M.J. (2005)
Transforming growth factor-beta suppresses the ability of Ski to inhibit tumor metastasis by inducing its degradation. (PubMed id 18451154)^{1, 3} Le Scolan E....Luo K. (2008)
Nuclear and cytoplasmic c-Ski differently modulate cellular functions. (PubMed id 17054724)^{1, 3} Nagata M....Miyazono K. (2006)
The transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteins. (PubMed id 12764135)^{1, 3} He J....Luo K. (2003)
Increased expression of c-Ski as a co-repressor in transforming growth factor-beta signaling correlates with progression of esophageal squamous cell carcinoma. (PubMed id 14712482)^{1, 3} Fukuchi M....Kuwano H. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 6497	HGNC: 10896	AceView: SKI	Ensembl:ENSG00000157933	euGenes: HUgn6497
ECgene: SKI	H-InvDB: SKI

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for SKI	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for SKI
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for SKI:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for SKI-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for SKI		Antibodies for SKI
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for SKI		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Flow Cytometry Kits		Protease Activity Assays & Reagents
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	Recombinant & Natural Proteins

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Search Tocris compounds for SKI

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SKI Gene

protein-coding GIFtS: 66

Aliases &
Descriptions
for SKI

Summaries
for SKI

Genomic Location
for SKI

Proteins
for SKI

Protein Domains/
Families
for SKI

Gene Function
for SKI

Pathways & Interactions
for SKI

Drugs & Compounds
for SKI

Transcripts
for SKI

Expression
for SKI

Orthologs
for SKI

Paralogs
for SKI

SNPs/Variants
for SKI

Disorders & Mutations
for SKI

Medical News
for SKI

Publications
for SKI

Search for SKI

Genome Databases showing SKI

Other Databases showing SKI

Specialized Databases showing SKI

Licensable Technologies
for SKI

Services
for SKI

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

SKI Gene

protein-coding GIFtS: 66

Aliases & Descriptionsfor SKI

Summariesfor SKI

Genomic Locationfor SKI

Proteinsfor SKI

Protein Domains/Familiesfor SKI

Gene Functionfor SKI

Pathways & Interactionsfor SKI

Drugs & Compoundsfor SKI

Transcriptsfor SKI

Expression for SKI

Orthologsfor SKI

Paralogsfor SKI

SNPs/Variantsfor SKI

Disorders & Mutationsfor SKI

Medical Newsfor SKI

Publicationsfor SKI

Search for SKI

Genome Databases showing SKI

Other Databases showing SKI

Specialized Databases showing SKI

Licensable Technologiesfor SKI

Servicesfor SKI

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for SKI

Summaries
for SKI

Genomic Location
for SKI

Proteins
for SKI

Protein Domains/
Families
for SKI

Gene Function
for SKI

Pathways & Interactions
for SKI

Drugs & Compounds
for SKI

Transcripts
for SKI

Expression
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Disorders & Mutations
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Medical News
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Publications
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