Aliases for SKI Gene
External Ids for SKI Gene
Previous GeneCards Identifiers for SKI Gene
This gene encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation. [provided by RefSeq, Oct 2009]
GeneCards Summary for SKI Gene
SKI (SKI Proto-Oncogene) is a Protein Coding gene. Diseases associated with SKI include shprintzen-goldberg syndrome and cole-carpenter syndrome 2. Among its related pathways are Gene Expression and Signaling by GPCR. GO annotations related to this gene include chromatin binding and ubiquitin protein ligase binding. An important paralog of this gene is SKIL.
UniProtKB/Swiss-Prot for SKI Gene
May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling.