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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SKAP2 Gene

protein-coding   GIFtS: 56
GCID: GC07M026706

src kinase associated phosphoprotein 2

(Previous name: src family associated phosphoprotein 2 )
(Previous symbol: SCAP2)
 Explore 19 diseases affiliated with
SKAP2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SKAP2    

Aliases
for SKAP2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Src Kinase Associated Phosphoprotein 21 2     Src-Associated Adapter Protein With PH And SH3 Domains2 3
SCAP21 2 3 5     PRAP2 3
SKAP55R1 2 3 5     SKAP-55HOM2 3
RA701 2 3     Pyk2/RAFTK-Associated Protein2 3
SAPS1 2 3     SKAP55 Homolog2 3
SKAP-HOM1 2 3     Fyn-Associated Phosphoprotein SKAP55 Homologue2
Src Family Associated Phosphoprotein 21 2     Src Kinase-Associated Phosphoprotein 22
Retinoic Acid-Induced Protein 702 3     Src Kinase-Associated Phosphoprotein Of 55-Related Protein2
Src Family-Associated Phosphoprotein 22 3     Src-Associated Adaptor Protein2
Src Kinase-Associated Phosphoprotein 55-Related Protein2 3     

External Ids:    HGNC: 156871   Entrez Gene: 89352   Ensembl: ENSG000000050207   OMIM: 6052155   UniProtKB: O755633   

Export aliases for SKAP2 gene to outside databases

Previous GC identifer: GC07M026674


Summaries
for SKAP2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SKAP2:
The protein encoded by this gene belongs to the src family kinases. This protein is similar to the src kinase
associated phosphoprotein 1. It is an adaptor protein that is thought to play an essential role in the src signaling
pathway in various cells. It inhibits PTK2B/RAFTK activity and regulates alpha-synuclein phosphorylation. (provided by
RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: SKAP2_HUMAN, O75563
Function: May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell
receptor (BCR) to integrin activation. May play a role in src signaling pathway

Gene Wiki entry for SKAP2


Genomic Views
for SKAP2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SKAP2 gene promoter:
         ER-alpha   LCR-F1   MEF-2A   POU2F1   CBF-A   CBF-B   POU2F1a   CP1A   aMEF-2   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): SKAP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for SKAP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SKAP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15.2   Ensembl cytogenetic band:  7p15.2   HGNC cytogenetic band: 7p15.2

SKAP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SKAP2 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M026706:  view genomic region     (about GC identifiers)

Start:
 26,706,681 bp from pter      End:
 27,034,858 bp from pter
Size:
 328,178 bases      Orientation:
 minus strand

1 alternative location:
Chr7-,CRA_TCAG 26,757,875-26,955,499     

Proteins
for SKAP2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SKAP2_HUMAN, O75563 (See protein sequence)
Recommended Name: Src kinase-associated phosphoprotein 2  
Size: 359 amino acids; 41217 Da
Subunit: Homodimer (By similarity). Interacts with PTPNS1. Part of a complex consisting of SKAP2, FYB and PTPNS1. Part
of a complex consisting of SKAP2, FYB and LILRB3. May interact with actin (By similarity). Interacts with FYB, which
is required for SKAP2 protein stability. Interacts with LAT, GRB2, PTK2B and PRAM1. May interact with FYN, HCK and
LYN. Interacts with FASLG
Subcellular location: Cytoplasm
1 PDB 3D structure from and Proteopedia for SKAP2:
3OMH (3D)    
Secondary accessions: A4D173 Q53GP6 Q75MK6 Q75MZ4 Q9UBZ3 Q9UED8

Explore the universe of human proteins at neXtProt for SKAP2: NX_O75563

Post-translational modifications:

  • Phosphorylated in resting platelets. Phosphorylated by FYN on Tyr-261 upon T-cell activation (Probable).
    • Dephosphorylated on Tyr-75 by PTPN221
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O75563

    • SKAP2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_003921.2  
    ENSEMBL proteins: 
     ENSP00000005587   ENSP00000408163   ENSP00000443593  
    Reactome Protein details: O75563
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: SKAP2
    OriGene Protein Over-expression Lysate: SKAP2
    OriGene Custom Protein Services for SKAP2 
    GenScript Custom Purified and Recombinant Proteins Services for SKAP2
    Novus Biologicals SKAP2 Proteins
    Novus Biologicals SKAP2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SKAP2

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005829cytosol TAS--
    GO:0005886plasma membrane IDA11390434


    SKAP2 for ontologies           About GeneDecksing



    SKAP2 Antibody Products: 
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    Novus Biologicals SKAP2 Antibodies
    Abcam antibodies for SKAP2 
    Uscn Antibodies for SKAP2
    ThermoFisher Antibodies for SKAP2

    Assay Products for SKAP2: 
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    Browse OriGene Fluorogenic Cell Assay Kits
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    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for SKAP2

    Protein Domains /
    Families
    for SKAP2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SKAP2 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001849 Pleckstrin_homology
     IPR001452 SH3_domain
     IPR011993 PH_like_dom

    Graphical View of Domain Structure for InterPro Entry O75563

    ProtoNet protein and cluster: O75563

    2 Blocks protein families:
    IPB001452 SH3 domain signature
    IPB001849 Pleckstrin-like


    UniProtKB/Swiss-Prot: SKAP2_HUMAN, O75563
    Domain: The SH3 domain interacts with FYB and PTK2B
    Similarity: Belongs to the SKAP family
    Similarity: Contains 1 PH domain
    Similarity: Contains 1 SH3 domain


    Function
    for SKAP2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SKAP2_HUMAN, O75563
    Function: May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell
    receptor (BCR) to integrin activation. May play a role in src signaling pathway
    Induction: By retinoic acid

    miRNA
    Products:            		 OriGene 3'-UTR Clone: SKAP2
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SKAP2
    8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate SKAP2 (see all 38):
    hsa-miR-3678-3p hsa-miR-579 hsa-miR-642a hsa-miR-4254 hsa-miR-193a-3p hsa-miR-1224-3p hsa-miR-759 hsa-miR-889
    SwitchGear 3'UTR luciferase reporter plasmid: SKAP2 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SKAP2 (see all 4)
    OriGene shRNA RFP: SKAP2
    OriGene siRNA: SKAP2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SKAP2

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for SKAP2

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SKAP2 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SKAP2
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: SKAP2 (NM_003930)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SKAP2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SKAP2 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for SKAP2
    Search LifeMap BioReagents cell lines for SKAP2

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SKAP2

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005070SH3/SH2 adaptor activity TAS9671755
    GO:0005543phospholipid binding IEA--


    SKAP2 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SKAP2:
     Decreased DCP1a protein expres 

    Animal Models:
         3 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Skap2):
     cellular  hematopoietic system  immune system 

    SKAP2 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for SKAP2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Signal regulatory protein (SIRP) family interactions
    		Signal regulatory protein (SIRP) family interactions1.00
    2Cell-cell junction organization
    		Cell-Cell communication0.45

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    2        Reactome Pathways for SKAP2
        Signal regulatory protein (SIRP) family interactions
    Cell-Cell communication



    SKAP2 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SKAP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    5/23 Interacting proteins for SKAP2 (O755633 ENSP000000055874) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FYNP062413, ENSP000003576564I2D: score=4 STRING: ENSP00000357656
    HCKP086313, ENSP000003650124I2D: score=3 STRING: ENSP00000365012
    FYBO151173, ENSP000003164604I2D: score=1 STRING: ENSP00000316460
    PRAM1Q96QH23, ENSP000002556124I2D: score=1 STRING: ENSP00000255612
    GRB2P629933, ENSP000003390074I2D: score=1 STRING: ENSP00000339007
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006461protein complex assembly TAS9671755
    GO:0007165signal transduction TAS9837776
    GO:0008285negative regulation of cell proliferation IEA--
    GO:0042113B cell activation IEA--


    SKAP2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SKAP2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SKAP2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SKAP2
    9 Novoseek chemical compound relationships for SKAP2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    saquinavir 72.2 5 11476984 (1), 11322888 (1), 17954688 (1), 12621090 (1)
    ritonavir 61.3 4 11476984 (1), 11322888 (1), 17954688 (1)
    indinavir 60.1 2 11476984 (1), 11322888 (1)
    amprenavir 57.7 1 12621090 (1)
    nelfinavir 48.2 1 11322888 (1)
    glycosphingolipid 47.5 1 16618109 (1)
    anti-fungal 21.1 1 12621090 (1)
    aspartate 17.7 3 16897584 (1), 11291571 (1), 9485603 (1)
    tyrosine 0 2 9755858 (1), 12893833 (1)

    Search CenterWatch for drugs/clinical trials and news about SKAP2 

    Transcripts
    for SKAP2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SKAP2 gene: 
    NM_003930.3  

    Unigene Clusters for SKAP2:

    Src kinase associated phosphoprotein 2
    Hs.200770  [show with all ESTs], Hs.610137  [show with all ESTs]
    Unigene Representative Sequences: NM_003930, BQ708363
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000345317(uc011jzi.2 uc003syc.3 uc011jzj.2) ENST00000489977
    ENST00000468712 ENST00000495802 ENST00000432747 ENST00000490456 ENST00000497511
    ENST00000481204 ENST00000487720 ENST00000539623

    miRNA
    Products:             		 OriGene 3'-UTR Clone: SKAP2
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SKAP2
    8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate SKAP2 (see all 38):
    hsa-miR-3678-3p hsa-miR-579 hsa-miR-642a hsa-miR-4254 hsa-miR-193a-3p hsa-miR-1224-3p hsa-miR-759 hsa-miR-889
    SwitchGear 3'UTR luciferase reporter plasmid: SKAP2 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SKAP2 (see all 4)
    OriGene shRNA RFP: SKAP2
    OriGene siRNA: SKAP2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SKAP2
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SKAP2 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SKAP2
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: SKAP2 (NM_003930)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SKAP2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SKAP2 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SKAP2
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SKAP2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SKAP2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SKAP2

    Additional cDNA sequence: 

    AB063661.1 AB063671.1 AB063791.1 AB063873.1 AB063905.1 AB063909.1 AB063910.1 AB063911.1 
    AB066896.1 AB066900.1 AB066905.1 AB066909.1 AB066910.1 AB066914.1 AB066915.1 AB066916.1 
    AB066918.1 AB066919.1 AB066920.1 AB066921.1 AB066923.1 AB066924.1 AB066933.1 AB067034.1 
    AB067035.1 AB067036.1 AB067037.1 AB067038.1 AB067039.1 AB067040.1 AB067041.1 AB067044.1 
    AB067046.1 AB067049.1 AB067052.1 AB067053.1 AB067055.1 AB067056.1 AB067057.1 AB067058.1 
    AB067060.1 AB067064.1 AB067066.1 AB067067.1 AB067068.1 AB067084.1 AB067085.1 AB067088.1 
    AB067089.1 AB067090.1 AB067091.1 AB067092.1 AB067093.1 AB067120.1 AB067132.1 AB067133.1 
    AB067134.1 AB067135.1 AB067136.1 AB067137.1 AB067142.1 AB067143.1 AB067144.1 AB067145.1 
    AB067146.1 AB067148.1 AB067149.1 AB067151.1 AB067271.1 AB067274.1 AB067276.1 AB067278.1 
    AB067279.1 AB067282.1 AB067284.1 AB067289.1 AB067293.1 AB067298.1 AB067300.1 AB363098.1 
    AB363103.1 AB363104.1 AB363113.1 AB363131.1 AB363152.1 AB363153.1 AB363154.1 AB363224.1 
    AB374190.1 AB374203.1 AB374205.1 AF004936.1 AF004937.1 AF017459.1 AF017460.1 AF017461.1 
    AF017463.1 AF021948.1 AF021954.1 AF021957.1 AF021958.1 AF021975.1 AF021990.1 AF021991.1 
    AF022004.1 AF022005.1 AF052527.1 AF062101.1 AF062102.1 AF062104.1 AF062112.1 AF062113.1 
    AF062124.1 AF062128.1 AF062146.1 AF062148.1 AF062149.1 AF062152.1 AF062158.1 AF062173.1 
    AF062176.1 AF062181.1 AF062183.1 AF062187.1 AF062192.1 AF062196.1 AF062201.1 AF062204.1 
    AF062217.1 AF062218.1 AF062227.1 AF062231.1 AF062234.1 AF062239.1 AF062240.1 AF062244.1 
    AF062250.1 AF062278.1 AF062292.1 AF064878.1 AF064879.1 AF103048.1 AF103053.1 AF103061.2 
    AF103062.1 AF103065.1 AF103083.1 AF103094.1 AF103108.1 AF103173.1 AF103178.1 AF103236.1 
    AF103242.1 AF103277.2 AF103278.1 AF103287.1 AF103289.1 AF103299.1 AF103306.1 AF103313.1 
    AF103337.1 AF103340.1 AF103344.1 AF103362.1 AF103372.1 AF107233.1 AF107238.1 AF107239.1 
    AF107241.1 AF129752.1 AF174022.1 AF174032.1 AF174035.1 AF174041.1 AF174049.1 AF174053.1 
    AF174054.1 AF174078.1 AF174082.1 AF174085.1 AF174086.1 AF174087.1 AF174088.1 AF174124.1 
    AF174128.1 AF245309.2 AF283780.1 AF283781.1 AF283784.1 AF302819.1 AF361025.1 AF372845.1 
    AF396470.1 AF396472.1 AF396478.1 AF398963.1 AF408717.2 AF408738.1 AF417843.1 AF417844.1 
    AF455548.1 AF460681.1 AF460702.1 AF460703.1 AF460708.1 AF460712.1 AF460715.1 AF460721.1 
    AF460728.1 AF460736.1 AF460737.1 AF460739.1 AF460748.1 AF460749.1 AF460750.1 AF460752.1 
    AF460753.1 AF460755.1 AF460757.1 AF460762.1 AF460765.1 AF460785.1 AF460789.1 AF460792.1 
    AF460795.1 AF460796.1 AF460799.1 AF460808.1 AF460809.1 AF460810.1 AF460811.1 AF460812.1 
    AF460813.1 AF460814.1 AF460815.1 AF460816.1 AF460818.1 AF460819.1 AF460820.1 AF460821.1 
    AF460824.1 AF460828.1 AF460831.1 AF460832.1 AF460836.1 AF460837.1 AF460842.1 AF460843.1 
    AF484411.1 AJ008187.1 AJ222547.1 AJ222548.1 AJ222549.1 AJ222550.1 AJ222552.1 AJ222555.1 
    AJ222556.1 AJ222557.1 AJ222558.1 AJ222559.1 AJ222560.1 AJ222561.1 AJ222562.1 AJ222563.1 
    AJ222564.1 AJ222565.1 AJ222566.1 AJ222567.1 AJ222568.1 AJ222569.1 AJ222570.1 AJ222571.1 
    AJ222573.1 AJ222574.1 AJ222575.1 AJ222576.1 AJ222577.1 AJ222578.1 AJ233698.1 AJ233713.1 
    AJ235663.1 AJ239377.1 AJ240555.1 AJ240556.1 AJ240560.1 AJ240580.1 AJ240595.1 AJ241346.1 
    AJ241354.1 AJ241355.1 AJ244928.1 AJ244929.1 AJ244930.1 AJ244931.1 AJ244932.1 AJ244933.1 
    AJ244934.1 AJ244935.1 AJ244937.1 AJ244938.1 AJ244939.1 AJ244940.1 AJ244941.1 AJ244942.1 
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    DQ523886.1 DQ523887.1 DQ523893.1 DQ523894.1 DQ523900.1 DQ523902.1 DQ523906.1 DQ523909.1 
    DQ523912.1 DQ523927.1 DQ523928.1 DQ523929.1 DQ523930.1 DQ523931.1 DQ523933.1 DQ523935.1 
    DQ523946.1 DQ523947.1 DQ523950.1 DQ523952.1 DQ523955.1 DQ523959.1 DQ523960.1 DQ523972.1 
    DQ523975.1 DQ523980.1 DQ523984.1 DQ523987.1 DQ523988.1 DQ523990.1 DQ523991.1 DQ523999.1 
    DQ524000.1 DQ524001.1 DQ524003.1 DQ524006.1 DQ524007.1 DQ524008.1 DQ524009.1 DQ524012.1 
    DQ524017.1 DQ524018.1 DQ524027.1 DQ524030.1 DQ524032.1 DQ524035.1 DQ524038.1 DQ524044.1 
    DQ524060.1 DQ524061.1 DQ524065.1 DQ524068.1 DQ524077.1 DQ524096.1 DQ524102.1 DQ524131.1 
    DQ535279.1 DQ535289.1 DQ535294.1 DQ535296.1 DQ535314.1 DQ535320.1 DQ535326.1 DQ535329.1 
    DQ535370.1 DQ535393.1 DQ535421.1 DQ535427.1 DQ535433.1 DQ535455.1 DQ535456.1 DQ535459.1 
    EF028216.1 EF175396.1 EF175402.1 EF175407.1 EF175421.1 EF175423.1 EF175434.1 EF175437.1 
    EF407837.1 EF407849.1 EF441754.1 EF544958.1 EF583678.1 EF624236.1 EU090050.1 EU090244.1 
    EU099061.1 EU099068.1 EU099071.1 EU099076.1 EU099079.1 EU099089.1 EU099096.1 EU099098.1 
    EU099107.1 EU099109.1 EU099112.1 EU099123.1 EU099126.1 EU099131.1 EU099156.1 EU099169.1 
    EU099191.1 EU099227.1 EU099235.1 EU099252.1 EU099254.1 EU099255.1 EU099259.1 EU099267.1 
    EU099277.1 EU099278.1 EU146315.1 EU146343.1 EU146358.1 EU146377.1 EU146394.1 EU350428.1 
    EU433882.1 EU619988.1 EU620002.1 EU620038.1 EU937522.1 FJ039783.1 FJ039790.1 FJ039791.1 
    FJ039792.1 FJ208782.1 FJ385279.1 FJ385292.1 FJ385328.1 FJ385331.1 FJ385337.1 FJ385351.1 
    FJ385353.1 FJ385370.1 FJ385371.1 FJ385373.1 FJ385377.1 FJ385378.1 FJ385402.1 FJ385413.1 
    FJ385423.1 FJ385434.1 FJ385435.1 FJ492903.1 FJ492909.1 FJ492910.1 FJ840008.1 FJ840011.1 
    FJ840012.1 FJ840020.1 FJ840055.1 FJ840375.1 FJ840414.1 FJ840418.1 FJ840424.1 FJ873953.1 
    FJ874002.1 FJ874054.1 FJ874055.1 FJ874065.1 FJ874066.1 FJ874069.1 FJ874072.1 FJ874075.1 
    FJ874085.1 FJ874088.1 FJ874094.1 FJ874095.1 FR820867.1 FR820868.1 FR820869.1 FR820870.1 
    FR820871.1 FR820872.1 FR820873.1 FR820875.1 GQ504852.1 GQ504930.1 GQ504932.1 GQ504940.1 
    GU358660.1 GU358680.1 GU552721.1 GU552724.1 GU552725.1 GU552726.1 GU552727.1 GU552728.1 
    GU552729.1 GU552730.1 GU552731.1 GU552733.1 GU552736.1 GU552769.1 GU570263.1 GU570372.1 
    GU570373.1 GU570374.1 HM116105.1 HM116113.1 HM116114.1 HM116141.1 HM116146.1 HM116153.1 
    HM116155.1 HM116160.1 HM116162.1 HM116168.1 HM116169.1 HM116177.1 HM116182.1 HM116195.1 
    HM116199.1 HM116205.1 HM116208.1 HM116216.1 HM116219.1 HM116221.1 HM116222.1 HM152498.1 
    HM152499.1 HM152512.1 HM152516.1 HM152518.1 HM152521.1 HM152526.1 HM451490.1 HM774720.1 
    HM774736.1 HM774878.1 HM775069.1 HM994959.1 HM995092.1 HM995219.1 HM995239.1 HM995286.1 
    HM995287.1 HM995289.1 HM995291.1 HM995368.1 HM995370.1 HM995371.1 HM995396.1 HM995477.1 
    HM995479.1 HM995481.1 HM995513.1 HM995535.1 HM995549.1 HM995550.1 HM995552.1 HM995553.1 
    HM995554.1 HM995565.1 HM995651.1 HM995652.1 HM995654.1 HM995687.1 HM995693.1 HM995714.1 
    HM995715.1 HM995717.1 HM995718.1 HM995719.1 HM995720.1 HM995743.1 HM995865.1 HM995867.1 
    HM995920.1 HM996018.1 HM996057.1 HM996061.1 HM996124.1 HM996196.1 HM996197.1 HM996199.1 
    HM996206.1 HM996222.1 HM996223.1 HM996230.1 HM996236.1 HM996238.1 HM996243.1 HM996258.1 
    HM996265.1 HM996279.1 HM996415.1 HM996438.1 HM996480.1 HM996508.1 HM996519.1 HM996520.1 
    HM996535.1 HM996554.1 HQ378388.1 HQ392880.1 HQ392881.1 HQ392885.1 HQ392894.1 HQ392917.1 
    JF810276.1 JF810277.1 JF810279.1 JN110725.1 JN110760.1 JN110800.1 JN110847.1 JN110934.1 
    JN110965.1 JN110999.1 JN376171.1 JN376173.1 JN376176.1 JN376184.1 JN376186.1 JN376188.1 
    JN376189.1 JN376194.1 JN376195.1 JN376215.1 JN376216.1 JN376217.1 JN376224.1 JN376225.1 
    JN376226.1 JN376230.1 JN376231.1 JN376232.1 JN376233.1 JN376234.1 JN376235.1 JN376236.1 
    JN376254.1 JN376255.1 JN376256.1 JN376257.1 JN376266.1 JN376267.1 JN376268.1 JN376269.1 
    JN376285.1 JN376286.1 JN376287.1 JN376304.1 JN376305.1 JN376306.1 JN376310.1 JN376361.1 
    JN376366.1 JN376367.1 JN376411.1 JN376412.1 JN376413.1 JN376414.1 JN376415.1 JN376425.1 
    JN376426.1 JN376427.1 JN376428.1 JN376429.1 JN376436.1 JN376443.1 JN376444.1 JN376449.1 
    JN376461.1 JN376468.1 JN376492.1 JN376506.1 JN376509.1 JN376510.1 JN376511.1 JN376512.1 
    JN376513.1 JN376514.1 JN376515.1 JN376516.1 JN376517.1 JN376518.1 JN376519.1 JN376520.1 
    JN376521.1 JN376522.1 JN376523.1 JN376529.1 JN376530.1 JN376532.1 JN376535.1 JN376536.1 
    JN376537.1 JN376538.1 JN376541.1 JN376542.1 JN376543.1 JN376549.1 JN376614.1 JN376615.1 
    JN376616.1 JN376643.1 JN376644.1 JN376666.1 JN376667.1 JN376688.1 JN376713.1 JN376746.1 
    JN376749.1 JN376753.1 JQ304255.1 JQ304256.1 JQ304259.1 JQ304265.1 JQ304268.1 JX027465.1 
    JX173327.1 JX173330.1 JX173333.1 JX173348.1 JX173350.1 JX173359.1 L06023.1 L12109.1 
    L12190.1 L12192.1 L23518.1 L23556.1 L23934.1 L25291.1 L25293.1 L34163.1 
    L38425.1 L43087.1 L43117.1 M26998.1 M27768.1 M33859.1 M33860.1 M67501.1 
    M74018.1 M74021.1 M74469.1 M84508.1 M84512.1 M99601.1 M99607.1 S45207.1 
    S45947.1 S56197.1 S63731.1 S64473.1 S66098.1 S67110.1 S79918.1 U00494.1 
    U00497.1 U00556.1 U00566.1 U00571.1 U00578.1 U00581.1 U21257.1 U21267.1 
    U21268.1 U22391.1 U64496.1 U71103.1 U71106.1 U85233.1 U86523.1 U86524.1 
    U86799.1 U86800.1 U89766.1 U96278.1 U96280.1 U96285.1 U96287.1 U97243.1 
    U97246.1 X17678.1 X52110.1 X52895.1 X54437.1 X54441.1 X54447.1 X56158.1 
    X64152.1 X64153.1 X64156.1 X64159.1 X64234.1 X64235.1 X65903.1 X65904.1 
    X65911.1 X75022.1 X75024.1 X84336.1 X84339.1 X87438.1 X95660.1 Y08428.1 
    Y09249.1 Y09390.1 Y14936.1 Y17927.1 Y17928.1 Y17930.1 Y17931.1 Y17932.1 
    Y17933.1 Y17934.1 Y17943.1 Y17944.1 Y17945.1 Y17947.1 Y17948.1 Y17949.1 
    Z11941.1 Z14193.1 Z14195.1 Z14197.1 Z14198.1 Z14206.1 Z18828.1 Z30545.1 
    Z30547.1 Z30549.1 Z30550.1 Z30552.1 Z30554.1 Z30557.1 Z30561.1 Z30562.1 
    Z30573.1 Z30576.1 Z30578.1 Z30580.1 Z30581.1 Z30590.1 Z30591.1 Z30592.1 
    Z30596.1 Z30599.1 Z30671.1 Z30674.1 Z30675.1 Z30676.1 Z30677.1 Z30678.1 
    Z35126.1 Z35492.1 Z46269.1 Z46271.1 Z46273.1 Z46275.1 Z46277.1 Z46282.1 
    Z46300.1 Z46301.1 Z46302.1 Z46304.1 Z46305.1 Z46306.1 Z46307.1 Z46308.1 
    Z46315.1 Z46316.1 Z46317.1 Z46318.1 Z46319.1 Z46320.1 Z46321.1 Z46322.1 
    Z46323.1 Z46324.1 Z46325.1 Z46326.1 Z46327.1 Z46328.1 Z46329.1 Z46330.1 
    Z46331.1 Z46332.1 Z46333.1 Z46334.1 Z46335.1 Z46336.1 Z46337.1 Z46338.1 
    Z46339.1 Z46340.1 Z46341.1 Z46342.1 Z46769.1 Z46857.1 Z47228.1 Z47229.1 
    Z47234.1 Z47241.1 Z49135.1 Z49139.1 Z49141.1 Z49143.1 Z70604.1 Z70605.1 
    Z70606.1 Z70607.1 Z70608.1 Z70610.1 Z70616.1 Z70617.1 Z70618.1 Z70620.1 
    Z70621.1 Z70622.1 Z70623.1 Z70624.1 Z70625.1 Z70626.1 Z70627.1 Z70631.1 
    Z70632.1 Z70637.1 Z70638.1 Z70639.1 Z70640.1 Z70641.1 Z70642.1 Z70643.1 
    Z70644.1 Z70645.1 Z70646.1 Z70647.1 Z70648.1 Z70649.1 Z70650.1 Z70654.1 
    Z70655.1 Z70656.1 Z70657.1 Z74665.1 Z74671.1 Z74695.1 Z75362.1 Z75364.1 
    Z75365.1 Z75367.1 Z75369.1 Z75373.1 Z75374.1 Z75376.1 Z75377.1 Z75378.1 
    Z75379.1 Z75381.1 Z75383.1 Z75385.1 Z75387.1 Z75388.1 Z75389.1 Z75392.1 
    Z75394.1 Z75397.1 Z75398.1 

    24/871 DOTS entries (see all 871):

    DT.452743  DT.100060883  DT.98083054  DT.100666898  DT.100780946  DT.121651499  DT.100043168  DT.121506031 
    DT.100851394  DT.101987323  DT.121508967  DT.100035517  DT.121650696  DT.121651752  DT.121505803  DT.121508491 
    DT.100039782  DT.100043958  DT.121506265  DT.121509596  DT.91864019  DT.121506460  DT.121508259  DT.121508484 

    24/211 AceView cDNA sequences (see all 211):

    CD369002 AF072166 BQ433993 AI359445 AA987547 AW118308 CB111872 BM977805 
    AI446521 AA694478 BE042726 AA429629 AA282147 R81282 CA423048 BC002893 
    BM553523 BG111216 AI376596 AI766201 AI755164 AA748674 NM_003930 CB156628 

    GeneLoc Exon Structure


    Expression
    for SKAP2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SKAP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAGGGCACAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SKAP2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    PureStem™ progenitor RASMO12 (Embryonic Progenitor Cell)
    Posterior foregut-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See SKAP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SKAP2

    SOURCE GeneReport for Unigene clusters: Hs.200770 Hs.610137

    UniProtKB/Swiss-Prot: SKAP2_HUMAN, O75563
    Tissue specificity: Ubiquitously expressed. Present in platelets (at protein level)

        SABiosciences Custom PCR Arrays for SKAP2
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SKAP2
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SKAP2
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SKAP2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SKAP2
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SKAP2

    Orthologs
    for SKAP2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for SKAP2 gene from 4/14 species (see all 14)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SKAP21 src kinase associated phosphoprotein 2 79.34(n)
    76.65(a)    		   420629  XM_418727.3  XP_418727.2 
    lizard
    (Anolis carolinensis)    		 Reptilia SKAP26
    		 --
    		 75(a)
    		 1 ↔ 1
    		 GL343275.1(1733314-1786812)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.90072 Xenopus laevis transcribed sequence with moderate similarity more 79.92(n)    CD519925.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc659752 hypothetical protein MGC65975 74.65(n)   393601  BC057253.1 


    ENSEMBL Gene Tree for SKAP2 (if available)
    TreeFam Gene Tree for SKAP2 (if available) 

    Paralogs
    for SKAP2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SKAP2 gene
    SKAP12  
    2 SIMAP similar genes for SKAP2 using alignment to 2 protein entries:     SKAP2_HUMAN (see all proteins):
    SCAP2    SKAP1

    SKAP2 for paralogs           About GeneDecksing



    Genomic Variants
    for SKAP2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3220 NCBI SNPs in SKAP2 are shown (see all 3220)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 7 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1467262861,2
    		--26706212(+) AAAAAC/TGAAAC 1 -- ds50010--------
    rs1894835861,2
    		--26706279(+) GTCCTA/GTAATA 1 -- ds50010--------
    rs1811792331,2
    		--26706316(+) TAGCAC/TACAGT 1 -- ds50010--------
    rs1447988081,2
    		--26706406(+) TGTCA-/TTATGC 1 -- ds50010--------
    rs171542911,2
    		C,F,H,--26706477(+) AAGTCA/GTTTGT 1 -- ds500113Minor allele frequency- G:0.06NA NS EA WA 1620
    rs1852347311,2
    		--26706523(+) GCCCTA/GTTTCA 1 -- ds50010--------
    rs1900863711,2
    		--26706623(+) CAAATC/TAATCA 1 -- ds50010--------
    rs1403195561,2
    		--26706626(+) ATTAAG/TCATAA 1 -- ds50010--------
    rs1427142281,2
    		--26706742(+) CATTAG/TTGTAA 1 -- ut310--------
    rs171542951,2
    		C,F,H,--26706802(+) AAAATG/TCTATA 1 -- ut3112Minor allele frequency- T:0.04NA NS EA WA 1514

    HapMap Linkage Disequilibrium report for SKAP2 (26706681 - 26956681 bp, first 250kb of SKAP2)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SKAP2: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SKAP2
    DNA2.0 Custom Variant and Variant Library Synthesis for SKAP2

    Disorders / Diseases
    for SKAP2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SKAP2 for disorders           About GeneDecksing

    OMIM gene information: 605215    OMIM disorders: --

    19 diseases for SKAP2:    About MalaCards
    neuronal ceroid-lipofuscinosis    tarsal tunnel syndrome    candida glabrata    thoracic outlet syndrome
    ceroid lipofuscinosis    candidiasis    vulvovaginal candidiasis    lysosomal storage disease
    oral candidiasis    ulnar neuropathy    vulvovaginitis    acute promyelocytic leukemia
    vaginitis    neuropathy    pancreatic cancer    pancreatitis
    leukemia    cholesterol    neuronitis

    3 diseases from the University of Copenhagen DISEASES database for SKAP2:
    Candidiasis     Tarsal tunnel syndrome     Neuronal ceroid lipofuscinosis

    4 Novoseek disease relationships for SKAP2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    candidiasis 73.8 5 11476984 (2), 12182226 (1), 10733678 (1), 12437091 (1)
    oral candidiasis 67 3 11506465 (1), 15472333 (1)
    oropharyngeal 56.8 1 12437091 (1)
    immunodeficiency 21.3 3 17954688 (1), 12621090 (1)

    Human Genome Epidemiology (HuGE) Navigator: SKAP2 (5 documents)

    Export disorders for SKAP2 gene to outside databases

    Publications
    for SKAP2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SKAP2 gene, integrated from 9 sources (see all 80):
    (articles sorted by number of sources associating them with SKAP2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. RA70 is a src kinase-associated protein expressed ubiquitously. (PubMed id 9837776)1, 2, 3, 9 Kouroku Y.... Momoi T. (1998)
    2. SKAP-HOM, a novel adaptor protein homologous to the FYN-associated protein SKAP55. (PubMed id 9755858)1, 2, 3, 9 Marie-Cardine A.... Schraven B. (1998)
    3. Identification and characterization of a novel Pyk2/related adhesion focal tyrosine kinase-associated protein that inhibits alpha-synuclein phosphorylation. (PubMed id 12893833)1, 2, 9 Takahashi T.... Matsumoto M. (2003)
    4. FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells. (PubMed id 9671755)1, 2, 9 Liu J.... Rudd C.E. (1998)
    5. Substrate specificity of lymphoid-specific tyrosine p hosphatase (Lyp) and identification of Src kinase-associated protein of 55 kDa homolog (SKAP-HOM) as a Lyp substrate. (PubMed id 21719704)1, 2 Yu X....Zhang Z.Y. (2011)
    6. Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. (PubMed id 19807924)1, 2 Voss M....Janssen O. (2009)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    9. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    10. PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells. (PubMed id 11301322)1, 2 Moog-Lutz C....Koretzky G. (2001)

    External Searches for SKAP2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing SKAP2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8935 HGNC: 15687 AceView: SCAP2 Ensembl:ENSG00000005020 euGenes: HUgn8935
    ECgene: SKAP2 H-InvDB: SKAP2

    Other Databases showing SKAP2 gene

    (According to HUGE)
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    Specialized Databases showing SKAP2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SKAP2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SKAP2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SKAP2 gene:
    Search GeneIP for patents involving SKAP2

    GeneCards and IP:
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