SKAP1 Gene
protein-coding GIFtS: 56
GCID: GC17M046210
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|
src kinase associated phosphoprotein 1(Previous name: src family associated phosphoprotein 1 )
(Previous symbol: SCAP1)
| |
Aliases
for SKAP1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Src Kinase Associated Phosphoprotein 11 2 | | Src Kinase-Associated Phosphoprotein Of 55 KDa2 3 | | SCAP11 2 3 5 | | SKAP-552 3 | | SKAP551 2 3 5 | | Pp551 | | Src Family Associated Phosphoprotein 11 2 | | Src Kinase-Associated Phosphoprotein 12 | | Src Family-Associated Phosphoprotein 12 3 | | |
Export aliases for SKAP1 gene to outside databasesPrevious GC identifers: GC17M043566 GC17M041580 |
Summaries
for SKAP1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SKAP1:
This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable ofrecruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a uniqueN-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion anddegranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by couplingT-cell antigen receptor stimulation to the activation of integrins. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: SKAP1_HUMAN, Q86WV1Function: Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimalconjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surfaceof T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells
Gene Wiki entry for SKAP1
|
Genomic Views
for SKAP1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SKAP1 gene promoter:
AP-1 ATF-2 MyoD YY1 c-Ets-1 MEF-2A FAC1 GATA-6 c-Jun aMEF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for SKAP1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SKAP1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q21.32 Ensembl cytogenetic band: 17q21.32 HGNC cytogenetic band: 17q21.32SKAP1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M046210: view genomic region
(about GC identifiers)
Start:
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46,210,802 bp from pter |
End:
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46,507,637 bp from pter |
Size:
|
296,836 bases |
Orientation:
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minus strand |
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Proteins
for SKAP1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SKAP1_HUMAN, Q86WV1 (See
protein sequence)Recommended Name: Src kinase-associated phosphoprotein 1 Size: 359 amino acids; 41432 Da
Subunit: Homodimer. Interacts with FYN and PTPRC. Interacts with GRB2 when phosphorylated on Tyr-271. Interacts withFYB, which is required for SKAP2 protein stability. Part of a complex consisting of SKAP1, FYB and CLNK. Interactswith RASGRP1
Subcellular location: Cytoplasm. Nucleus. Cell membrane. Note=Upon T-cell stimulation, translocates to lipid rafts atthe cell membrane
1 PDB 3D structure from  and Proteopedia  for SKAP1:1U5D (3D)
Secondary accessions: D3DTV1 O15268Alternative splicing: 2 isoforms: Q86WV1-1 Q86WV1-2 Explore the universe of human proteins at neXtProt for SKAP1: NX_Q86WV1
Post-translational modifications:
Phosphorylated on tyrosines. Phosphorylation by FYN on Tyr-271 is required for GRB2 interaction. Phosphorylation by FYNon Tyr-295 abolishes interaction with FYB. Tyr-232 is dephosphorylated by PTPRC (Probable)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86WV1
SKAP1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001068567.1 NP_003717.3
ENSEMBL proteins: ENSP00000338171 ENSP00000463284 ENSP00000464509 ENSP00000464311 ENSP00000462360 ENSP00000464198 ENSP00000462437
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
SKAP1 for ontologies About GeneDecksing
SKAP1 Antibody Products:
Assay Products for SKAP1: |
Protein
Domains /
Families
for SKAP1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SKAP1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q86WV1ProtoNet protein and cluster: Q86WV1 2 Blocks protein families: IPB001452 SH3 domain signature IPB001849 Pleckstrin-like
UniProtKB/Swiss-Prot: SKAP1_HUMAN, Q86WV1Domain: The SH3 domain interacts with FYBSimilarity: Belongs to the SKAP familySimilarity: Contains 1 PH domainSimilarity: Contains 1 SH3 domain |
Function
for SKAP1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SKAP1_HUMAN, Q86WV1Function: Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimalconjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surfaceof T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SKAP1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for SKAP1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SKAP1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SKAP1 |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
SKAP1 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for SKAP1:
Animal Models:
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Skap1):
SKAP1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SKAP1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | B cell receptor signaling pathway | |
1  BioSystems Pathway for SKAP1
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SKAP1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/15 Interacting proteins for SKAP1 (Q86WV11, 2, 3 ENSP000003381714) via UniProtKB, MINT, STRING, and/or I2D (see all 15)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| FYB | O151171, 2, 3, ENSP000003164604 | EBI-2477305,EBI-1753267 MINT-7147955 MINT-7147875 MINT-7148011 MINT-7147926 I2D:
score=3 STRING: ENSP00000316460 | | FYN | P062412, 3, ENSP000003576564 | MINT-8031426 I2D:
score=4 STRING: ENSP00000357656 | | GRB2 | P629932, 3, ENSP000003390074 | MINT-8031437 I2D:
score=4 STRING: ENSP00000339007 | | LCK | P062393, ENSP000003378254 | I2D:
score=3 STRING: ENSP00000337825 | | PTPRC | P085753, ENSP000003563464 | I2D:
score=3 STRING: ENSP00000356346 |
About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
SKAP1 for ontologies About GeneDecksing
|
Drugs & Compounds
for SKAP1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SKAP1 for compounds About GeneDecksing
 Browse Tocris compounds for SKAP1
1 Novoseek chemical compound relationship for SKAP1 gene About this table
Search CenterWatch for drugs/clinical trials and news about SKAP1
|
Transcripts
for SKAP1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SKAP1 gene (2 alternative transcripts): NM_001075099.1 NM_003726.3 Unigene Cluster for SKAP1: Src kinase associated phosphoprotein 1 Hs.316931 [show with all ESTs]Unigene Representative Sequence: BC0390408 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000336915 ENST00000584709(uc002ini.1 uc002inj.1 uc010dbd.1)
ENST00000583844 ENST00000579476 ENST00000584924(uc010dbe.1) ENST00000581400
ENST00000579336 ENST00000581419
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SKAP1 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SKAP1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): SKAP1 (NM_003726) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SKAP1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SKAP1 |
Additional cDNA sequence: AK290818.1 BC039040.1 BC047870.1 Y11215.1 6 DOTS entries: DT.443453 DT.92420241 DT.95263900 DT.100726926 DT.100748501 DT.438360 24/45 AceView cDNA sequences (see all 45): AA809983 AI216616 AA515886 BC039040 AA342347 AA995906 BC047870 CB157324 BG197139 AA342346 Y11215 BQ879838 BI906566 NM_003726 BX099494 BF511972 AA738043 CD556518 AW134687 AI760627 BM918438 CB985047 CB162087 AA904648
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SKAP1 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | · | 12c | ^ | 13 | ^ | 14a | · | 14b |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for SKAP1
|
Expression
for SKAP1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SKAP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATGGCTGGT
About this image
See SKAP1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SKAP1
SOURCE GeneReport for Unigene cluster: Hs.316931
UniProtKB/Swiss-Prot: SKAP1_HUMAN, Q86WV1Tissue specificity: Highly expressed in thymocytes and peripheral blood lymphocytes. Also expressed in spleen cells andtestis. Present in T-cells (at protein level)
SABiosciences Custom PCR Arrays for SKAP1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SKAP1
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SKAP1 |
Orthologs
for SKAP1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for SKAP1 gene from 4/12 species (see all 12) About this table
ENSEMBL Gene Tree for SKAP1 (if available)
TreeFam Gene Tree for SKAP1 (if available) |
Paralogs
for SKAP1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SKAP1 gene
- SKAP22
3 SIMAP similar genes for SKAP1 using alignment to 6 protein entries: SKAP1_HUMAN (see all proteins):IFT122 SKAP2 SCAP2
SKAP1 for paralogs About GeneDecksing
|
Genomic Variants
for SKAP1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SKAP1 (46210802 - 46460802 bp, first 250kb of SKAP1)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SKAP1
1 CNV: 67214 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SKAP1 |
|
Disorders
/ Diseases
for SKAP1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SKAP1 for disorders About GeneDecksing
OMIM gene information: 604969
OMIM disorders: --
1  disease for SKAP1: About MalaCardsovarian cancer
Human Genome Epidemiology (HuGE) Navigator: SKAP1 (2 documents)
Export disorders for SKAP1 gene to outside databases
|
Publications
for SKAP1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SKAP1 gene, integrated from 9 sources (see all 34):
(articles sorted by number of sources associating them with SKAP1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning of SKAP55, a novel protein that associates with p59fyn in human T-lymphocytes. (PubMed id 9195899)1, 2, 3, 9 Marie-Cardine A....Schraven B. (1997)
- SKAP55 modulates T cell antigen receptor-induced activation of the Ras-Erk-AP1 pathway by binding RasGRP1. (PubMed id 17658605)1, 2, 9 Kosco K.A....Mustelin T. (2008)
- Deficiency of ADAP/Fyb/SLAP-130 destabilizes SKAP55 in Jurkat T cells. (PubMed id 15849195)1, 2, 9 Huang Y....Wange R.L. (2005)
- SKAP55 recruits to lipid rafts and positively mediates the MAPK pathway upon T cell receptor activation. (PubMed id 12171928)1, 2, 9 Wu L.... Shen S.-H. (2002)
- Molecular interaction between the Fyn-associated protein SKAP55 and the SLP-76-associated phosphoprotein SLAP-130. (PubMed id 9748251)1, 2, 9 Marie-Cardine A.... Koretzky G.A. (1998)
- FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells. (PubMed id 9671755)1, 2, 9 Liu J.... Rudd C.E. (1998)
- The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1. (PubMed id 16980616)1, 2, 9 Kliche S.... Schraven B. (2006)
- Regulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor protein. (PubMed id 16461356)1, 2 Duke-Cohan J.S.... Rudd C.E. (2006)
- An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R. (PubMed id 15939789)1, 2 Jo E.-K.... Rudd C.E. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
|
External Searches for SKAP1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SKAP1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SKAP1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SKAP1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SKAP1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SKAP1 gene:
Search GeneIP for patents involving SKAP1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SKAP1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SKAP1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SKAP1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SKAP1 | | | OriGene Protein Over-expression Lysate for SKAP1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SKAP1 | | OriGene 3'-UTR Clone for SKAP1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SKAP1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SKAP1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SKAP1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SKAP1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SKAP1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SKAP1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SKAP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SKAP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SKAP1 |
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 |  |  |  | |
| | | | Search Tocris compounds for SKAP1 |
| |  |  |  |  | | | | |
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 | | | SKAP1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SKAP1 |
|  |  |  | | | | ThermoFisher Antibody for SKAP1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SKAP1 |
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