SIT1 Gene
protein-coding GIFtS: 52
GCID: GC09M035640
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|
signaling threshold regulating transmembrane adaptor 1(Previous name: suppression inducing transmembrane adaptor 1 )
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Aliases
for SIT1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Signaling Threshold Regulating Transmembrane Adaptor 11 2 | | RP11-331F9.52 | | SIT1 2 3 5 | | SIT-R2 | | Suppression Inducing Transmembrane Adaptor 11 2 | | SHP-2 Interacting Transmembrane Adaptor Protein2 | | Suppression-Inducing Transmembrane Adapter 12 3 | | SHP2 Interacting Transmembrane Adaptor2 | | Gp30/401 | | SHP2-Interacting Transmembrane Adaptor Protein2 | | SHP2-Interacting Transmembrane Adapter Protein2 3 | | Signaling Threshold-Regulating Transmembrane Adapter 12 |
Export aliases for SIT1 gene to outside databases |
Summaries
for SIT1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: SIT1_HUMAN, Q9Y3P8Function: Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positiveselection of T-cells
Gene Wiki entry for SIT1
|
Genomic Views
for SIT1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008413.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SIT1 gene promoter:
IRF-2 Sp1 p300 Lmo2 LCR-F1 Tal-1beta ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for SIT1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SIT1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9p13-p12 Ensembl cytogenetic band: 9p13.3 HGNC cytogenetic band: 9p13-p12SIT1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M035640: view genomic region
(about GC identifiers)
Start:
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35,649,292 bp from pter |
End:
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35,650,947 bp from pter |
Size:
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1,656 bases |
Orientation:
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minus strand |
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Proteins
for SIT1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SIT1_HUMAN, Q9Y3P8 (See
protein sequence)Recommended Name: Signaling threshold-regulating transmembrane adapter 1 precursor Size: 196 amino acids; 21126 Da
Subunit: Homodimer; disulfide-linked. When phosphorylated, interacts with PTPN11/SHP2, GRB2 and CSK
Subcellular location: Cell membrane; Single-pass type I membrane protein
Caution: In contrast to its orthologs it harbors a signal sequence
Secondary accessions: B2RBP9Explore the universe of human proteins at neXtProt for SIT1: NX_Q9Y3P8
Post-translational modifications:
Phosphorylated on tyrosines by LCK, FYN or ZAP70 upon TCR activation; which leads to the recruitment of PTPN11, GRB2and CSK1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y3P8
SIT1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055265.1
ENSEMBL proteins: ENSP00000259608
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
SIT1 for ontologies About GeneDecksing
SIT1 Antibody Products:
Assay Products for SIT1: |
Protein
Domains /
Families
for SIT1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9Y3P8 |
Function
for SIT1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SIT1_HUMAN, Q9Y3P8Function: Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positiveselection of T-cells
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SIT1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SIT1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SIT1 (NM_014450) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SIT1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SIT1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIT1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
SIT1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SIT1:
Animal Models:
Mouse knock-out Sit1tm1Lsmn for SIT1
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Sit1):
SIT1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SIT1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SIT1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/7 Interacting proteins for SIT1 (Q9Y3P82, 3 ENSP000002596084) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
SIT1 for ontologies About GeneDecksing
|
Drugs & Compounds
for SIT1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SIT1 for compounds About GeneDecksing
 Browse Tocris compounds for SIT1
1 Novoseek chemical compound relationship for SIT1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tyrosine |
37 |
4 |
11433379 (3) |
Search CenterWatch for drugs/clinical trials and news about SIT1
|
Transcripts
for SIT1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SIT1 gene: NM_014450.2 Unigene Cluster for SIT1: Signaling threshold regulating transmembrane adaptor 1 Hs.88012 [show with all ESTs]Unigene Representative Sequence: BQ0565683 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000259608(uc003zxe.1) ENST00000486859 ENST00000474403
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SIT1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SIT1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SIT1 (NM_014450) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SIT1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SIT1 |
Additional cDNA sequence: AJ010059.1 AK314758.1 BC102029.1 BC104491.1 BC107484.1 JQ924063.1 3 DOTS entries: DT.109933 DT.95159963 DT.102822261 24/158 AceView cDNA sequences (see all 158): AA421195 BE728707 BQ066178 CA488943 BF796667 AI792283 AW404968 AY390225 CR624155 BQ054614 AI732738 AA356801 CR617531 BQ063924 BC033666 BM680405 BE561205 AA252797 AA714519 AA746595 BF436061 BC038673 NM_014450 AY390226
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for SIT1 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b |
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| SP1: | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | - | | | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for SIT1
|
Expression
for SIT1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SIT1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACTGTTTCCC
About this image
See SIT1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SIT1
SOURCE GeneReport for Unigene cluster: Hs.88012
UniProtKB/Swiss-Prot: SIT1_HUMAN, Q9Y3P8Tissue specificity: Specifically expressed in T- and B-cells. Present in plasma cells but not in germinal centerB-cells (at protein level). Expressed in T- and B-cell lymphoma
SABiosciences Custom PCR Arrays for SIT1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SIT1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SIT1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SIT1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SIT1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIT1 |
Orthologs
for SIT1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for SIT1 gene from 1/6 species (see all 6) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Sit11 , 5 |
suppression inducing transmembrane adaptor 11, 5 |
83.33(n)1
78.41(a)1 |
|
4 (23.04 cM)5
543901 NM_019436.31 NP_062309.21
434820815 |
ENSEMBL Gene Tree for SIT1 (if available)
TreeFam Gene Tree for SIT1 (if available) |
Paralogs
for SIT1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SIT1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SIT1 (35649292 - 35650947 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SIT1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SIT1 |
|
Disorders
/ Diseases
for SIT1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SIT1 for disorders About GeneDecksing
OMIM gene information: 604964
OMIM disorders: --
3  diseases for SIT1: About MalaCardsmultidrug-resistant tuberculosis b-cell lymphomas tuberculosis
Human Genome Epidemiology (HuGE) Navigator: SIT1 (1 document)
Export disorders for SIT1 gene to outside databases
|
Publications
for SIT1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SIT1 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with SIT1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation. (PubMed id 10209036)1, 2, 3, 9 Marie-Cardine A....Schraven B. (1999)
- Complete sequence, genomic organization, and chromosomal localization of the human gene encoding the SHP2-interacting transmembrane adaptor protein (SIT). (PubMed id 11491537)1, 2, 3, 9 Huebener C.... Bruyns E. (2001)
- Structural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2-interacting transmembrane adaptor protein). (PubMed id 11433379)1, 2, 9 Pfrepper K.-I.... Schraven B. (2001)
- Transmembrane adaptor molecules: a new category of lymphoid-cell markers. (PubMed id 16160011)1, 2 Tedoldi S....Horejsi V. (2006)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
- Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- The transmembrane adaptor protein SIT inhibits TCR-me diated signaling. (PubMed id 21957439)1 Arndt B....Simeoni L. (2011)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
|
External Searches for SIT1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SIT1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SIT1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SIT1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SIT1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SIT1 gene:
Search GeneIP for patents involving SIT1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SIT1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SIT1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SIT1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SIT1 | | | OriGene Protein Over-expression Lysate for SIT1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SIT1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SIT1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SIT1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SIT1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SIT1 | | OriGene Custom Protein Services for SIT1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SIT1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SIT1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SIT1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SIT1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SIT1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SIT1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for SIT1 |
| |  |  |  |  | | | | | | Recombinant Protein for SIT1 |
|
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 | | | SIT1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIT1 |
|  |  |  | | | | ThermoFisher Antibody for SIT1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SIT1 |
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