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SIPA1L3 Gene

protein-coding   GIFtS: 55
GCID: GC19P038397

Signal-Induced Proliferation-Associated 1 Like 3

  Search for SIPA1L3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Signal-Induced Proliferation-Associated 1 Like 31 2     Signal-Induced Proliferation-Associated 1-Like Protein 32
SPAL32 3     SPA-1-Like 32
SIPA1-Like Protein 32 3     KIAA05453
SPA-1-Like Protein 32 3     

External Ids:    HGNC: 238011   Entrez Gene: 230942   Ensembl: ENSG000001057387   UniProtKB: O602923   

Export aliases for SIPA1L3 gene to outside databases

Previous GC identifers: GC19P043090 GC19P043264 GC19P034846


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SIPA1L3 Gene:
SIPA1L3 (signal-induced proliferation-associated 1 like 3) is a protein-coding gene. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is SIPA1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NT_011109.17  NC_018930.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for SIPA1L3
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SIPA1L3 promoter sequence
   Search Chromatin IP Primers for SIPA1L3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SIPA1L3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.13   Ensembl cytogenetic band:  19q13.13   HGNC cytogenetic band: 19q13.13

SIPA1L3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SIPA1L3 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P038397:  view genomic region     (about GC identifiers)

Start:
38,397,868 bp from pter      End:
38,699,012 bp from pter
Size:
301,145 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SI1L3_HUMAN, O60292 (See protein sequence)
Recommended Name: Signal-induced proliferation-associated 1-like protein 3  
Size: 1781 amino acids; 194610 Da
Secondary accessions: Q2TV87

Explore the universe of human proteins at neXtProt for SIPA1L3: NX_O60292

Explore proteomics data for SIPA1L3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SIPA1L3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055888.1  
    ENSEMBL proteins: 
     ENSP00000222345   ENSP00000472844   ENSP00000468981   ENSP00000471706   ENSP00000472734  

    SIPA1L3 Human Recombinant Protein Products:

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    Cloud-Clone Corp. CLIAs for SIPA1L3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR001478 PDZ
     IPR000331 Rap_GAP_dom
     IPR021818 DUF3401

    Graphical View of Domain Structure for InterPro Entry O60292

    ProtoNet protein and cluster: O60292

    1 Blocks protein domain: IPB000331 Rap/ran-GAP

    UniProtKB/Swiss-Prot: SI1L3_HUMAN, O60292
    Similarity: Contains 1 PDZ (DHR) domain
    Similarity: Contains 1 Rap-GAP domain


    SIPA1L3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005096GTPase activator activity IEA--
    GO:0005515protein binding ----
         
    SIPA1L3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SIPA1L3:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SIPA1L3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SIPA1L3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SIPA1L3

    miRNA
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    miRTarBase miRNAs that target SIPA1L3:
    hsa-mir-106a-5p (MIRT048328), hsa-mir-149-5p (MIRT045593), hsa-mir-615-3p (MIRT039665), hsa-mir-17-5p (MIRT050905), hsa-mir-375 (MIRT019987)

    Block miRNA regulation of human, mouse, rat SIPA1L3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SIPA1L3 (see all 56):
    hsa-miR-642a hsa-miR-302d hsa-miR-520e hsa-miR-4254 hsa-miR-106a hsa-miR-128 hsa-miR-507 hsa-miR-766
    SwitchGear 3'UTR luciferase reporter plasmidSIPA1L3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SIPA1L3
    Predesigned siRNA for gene silencing in human, mouse, rat SIPA1L3

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: SIPA1L3 (NM_015073)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SIPA1L3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SIPA1L3

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIPA1L3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA--

    SIPA1L3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SIPA1L3 About    
    See pathways by source

    SuperPathContained pathways About
    1Ras signaling pathway
    Rap1 signaling pathway0.36

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for SIPA1L3):
        Rap1 signaling pathway


    SIPA1L3 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SIPA1L3
    Interactions:

        Search GeneGlobe Interaction Network for SIPA1L3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for SIPA1L3 (O602922, 3 ENSP000002223454) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SFNP319472, 3MINT-3975312 I2D: score=2 
    YWHAZP631042, 3, ENSP000003095034MINT-3296030 I2D: score=1 STRING: ENSP00000309503
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    PLK2ENSP000002742894STRING: ENSP00000274289
    PLK3ENSP000003612754STRING: ENSP00000361275
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0051056regulation of small GTPase mediated signal transduction IEA--

    SIPA1L3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SIPA1L3 (SI1L3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SIPA1L3 gene: 
    NM_015073.2  

    Unigene Cluster for SIPA1L3:

    Signal-induced proliferation-associated 1 like 3
    Hs.655502  [show with all ESTs]
    Unigene Representative Sequence: NM_015073
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000222345(uc002ohk.3) ENST00000599644 ENST00000476317 ENST00000595982
    ENST00000595384 ENST00000601222 ENST00000594553 ENST00000601881 ENST00000600919
    ENST00000595495 ENST00000601054 ENST00000596403
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SIPA1L3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SIPA1L3 (see all 56):
    hsa-miR-642a hsa-miR-302d hsa-miR-520e hsa-miR-4254 hsa-miR-106a hsa-miR-128 hsa-miR-507 hsa-miR-766
    SwitchGear 3'UTR luciferase reporter plasmidSIPA1L3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SIPA1L3
    Predesigned siRNA for gene silencing in human, mouse, rat SIPA1L3
    Clone
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    OriGene clones in human, mouse for SIPA1L3 (see all 5)
    OriGene ORF clones in mouse, rat for SIPA1L3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SIPA1L3 (NM_015073)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SIPA1L3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SIPA1L3
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SIPA1L3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SIPA1L3
      QuantiTect SYBR Green Assays in human, mouse, rat SIPA1L3
      QuantiFast Probe-based Assays in human, mouse, rat SIPA1L3

    Additional mRNA sequence: 

    AB011117.2 AY168880.1 BC036863.1 BC150620.1 

    5 DOTS entries:

    DT.211352  DT.86846698  DT.92420546  DT.97777491  DT.121433451 

    Selected AceView cDNA sequences (see all 146):

    BF001536 BI770004 CB141350 AA768800 R13584 AI218347 AI873534 AL040865 
    AI701372 BX119674 BC036863 BF514240 CK825844 CK822912 CK822913 AL045302 
    BF512102 BU167319 BQ086199 AA938672 BF590866 BQ102303 AI436557 CD674977 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SIPA1L3    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19 ^ 20 ^ 21 ^ 22
    SP1:                                -                                   -                                   -                                                   
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            


    ECgene alternative splicing isoforms for SIPA1L3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SIPA1L3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTCTGGAGG
    SIPA1L3 Expression
    About this image

    SIPA1L3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SIPA1L3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.655502
        Custom PCR Arrays for SIPA1L3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIPA1L3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SIPA1L3 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sipa1l31 , 5 signal-induced proliferation-associated 1 like 31, 5 86.41(n)1
    91.54(a)1
      7 (16.94 cM)5
    742061  NM_001081028.11  NP_001074497.11 
     293203725 
    lizard
    (Anolis carolinensis)
    Reptilia SIPA1L36
    signal-induced proliferation-associated 1 like 3
    71(a)
    1 ↔ 1
    LGf(2490557-2598064)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.102582 Transcribed sequence with weak similarity to protein more 80.87(n)    AL884757.2 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-149j18.11 si:dkey-149j18.1 61.41(n)
    62(a)
      561005  XM_684403.3  XP_689495.2 


    ENSEMBL Gene Tree for SIPA1L3 (if available)
    TreeFam Gene Tree for SIPA1L3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SIPA1L3 gene
    SIPA12  SIPA1L12  RAP1GAP2  SIPA1L22  GARNL32  RAP1GAP22  
    Selected SIMAP similar genes for SIPA1L3 using alignment to 7 protein entries:     SI1L3_HUMAN (see all proteins) (see all similar genes):
    C14orf23    TNNT1    COQ5    FLJ00047    SUMO1    DNAPTP3
    ENTPD3    FAM138C    PACSIN2    OK/SW-cl.41    MST132    ZNF737
    GALK2    NLN    C14orf178    HBP1    AHSA1    ZNF114

    SIPA1L3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SIPA1L3 (see all 6343)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1806810451,2
    --38399374(+) ATTAAA/GTTATG 1 -- int10--------
    rs48035511,2
    C,F,A,H--38399461(+) CCCCAT/CAGAGC 1 -- int123Minor allele frequency- C:0.46NS EA NA WA CSA 2350
    rs1382932131,2
    C--38399609(+) TGGCT-/GGTTTC 1 -- int10--------
    rs1410304421,2
    --38399624(+) GCACCA/GTAAAC 1 -- int10--------
    rs1174405841,2
    C,F--38399782(+) AAGGAC/TGAAGC 1 -- int11Minor allele frequency- T:0.02EA 120
    rs1432780951,2
    --38399836(+) CCCATC/GTGATG 1 -- int10--------
    rs1836102441,2
    --38399871(+) GAGACA/GGAGTC 1 -- int10--------
    rs110834411,2
    C,F,A,H--38399930(+) GAAGCT/CTCCGT 1 -- int16Minor allele frequency- C:0.35NA WA CSA EA 130
    rs558135481,2
    C,F--38399940(+) TCTCCC/TGGGTT 1 -- int11Minor allele frequency- T:0.50NA 2
    rs1398989931,2
    --38399999(+) CCCGCC/TACCAC 1 -- int10--------

    HapMap Linkage Disequilibrium report for SIPA1L3 (38397868 - 38647868 bp, first 250kb of SIPA1L3)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for SIPA1L3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2658332CNV Deletion23128226
    esv2610413CNV Deletion19546169
    esv2670217CNV Deletion23128226
    esv2718531CNV Deletion23290073
    esv1080341CNV Insertion17803354
    nsv911657CNV Loss21882294
    nsv833820CNV Loss17160897
    nsv138463CNV Loss16902084
    nsv833821CNV Loss17160897
    nsv911656CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SIPA1L3
    DNA2.0 Custom Variant and Variant Library Synthesis for SIPA1L3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    SIPA1L3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SIPA1L3
    Human Genome Epidemiology (HuGE) Navigator: SIPA1L3 (1 document)

    Export disorders for SIPA1L3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SIPA1L3 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with SIPA1L3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (DNA Res. 2002)
    3. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)1, 2 Nagase T....Ohara O. (DNA Res. 1998)
    4. Proteomic investigation of the interactome of FMNL1 in hematopoietic cells unveils a role in calcium-dependent membrane plasticity. (PubMed id 23182705)1 Han Y....Krackhardt A.M. (J Proteomics 2013)
    5. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    6. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    7. 14-3-3 proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitylation and cytoplasmic body formation. (PubMed id 23444366)1 Ichimura T....Hachiya N. (J. Cell. Sci. 2013)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R.... Peters J.M. (Science 2010)
    10. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (Science 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23094 HGNC: 23801 AceView: SIPA1L3 Ensembl:ENSG00000105738 euGenes: HUgn23094
    ECgene: SIPA1L3 Kegg: 23094 H-InvDB: SIPA1L3

    (According to HUGE)
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    HUGE: KIAA0545

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SIPA1L3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SIPA1L3 gene:
    Search GeneIP for patents involving SIPA1L3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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