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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SIPA1L2 Gene

protein-coding GIFtS: 52
GCID: GC01M232533

signal-induced proliferation-associated 1 like 2

Search for SIPA1L2
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Signal-Induced Proliferation-Associated 1 Like 2¹ ²
KIAA1389¹ ³ ⁵
SIPA1-Like Protein 2² ³
SPAL2²
Signal-Induced Proliferation-Associated 1-Like Protein 2²
SPA-1-Like 2²

External Ids:	HGNC: 23800¹	Entrez Gene: 57568²	Ensembl: ENSG00000116991⁷	OMIM: 611609⁵	UniProtKB: Q9P2F8³

Export aliases for SIPA1L2 gene to outside databases

Previous GC identifers: GC01M229617 GC01M228840 GC01M230600 GC01M203022

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Gene Wiki entry for SIPA1L2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_167186.1

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SIPA1L2 gene promoter:
Nkx3-1 Bach1 Nkx3-1 v4 GCNF Nkx3-1 v1 NF-AT Nkx3-1 v2 GCNF-1 Nkx3-1 v3 GCNF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SIPA1L2 promoter sequence

Search SABiosciences Chromatin IP Primers for SIPA1L2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SIPA1L2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q42.2 Ensembl cytogenetic band: 1q42.2 HGNC cytogenetic band: 1q42.2

SIPA1L2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SIPA1L2 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M232533: view genomic region (about GC identifiers)

Start:	232,533,711 bp from pter	End:	232,697,304 bp from pter
Size:	163,594 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SI1L2_HUMAN, Q9P2F8 (See protein sequence)

Recommended Name: Signal-induced proliferation-associated 1-like protein 2

Size: 1722 amino acids; 190438 Da

Sequence caution: Sequence=BAA92627.1; Type=Erroneous initiation; Sequence=BAB14273.1; Type=Erroneous initiation;

Secondary accessions: Q2TV88 Q5VXR7 Q5VXR8 Q641Q4 Q8NA38 Q96DZ3 Q9H9F6

Alternative splicing: 2 isoforms: Q9P2F8-1 Q9P2F8-2

Explore the universe of human proteins at neXtProt for SIPA1L2: NX_Q9P2F8

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9P2F8

SIPA1L2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_065859.3

ENSEMBL proteins:

ENSP00000355589 ENSP00000309102 ENSP00000262861

Human Recombinant Protein Products:

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	Browse ProSpec Recombinant Proteins
	Uscn Proteins for SIPA1L2

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--

SIPA1L2 for ontologies About GeneDecksing

SIPA1L2 Antibody Products:

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	ThermoFisher Antibodies for SIPA1L2

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	Uscn ELISAs and CLIAs for SIPA1L2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SIPA1L2 for domains About GeneDecksing

3 InterPro domains/families:

IPR001478 PDZ

IPR000331 Rap_GAP_dom

IPR021818 DUF3401

Graphical View of Domain Structure for InterPro Entry Q9P2F8

ProtoNet protein and cluster: Q9P2F8

1 Blocks protein family: IPB000331 Rap/ran-GAP

UniProtKB/Swiss-Prot: SI1L2_HUMAN, Q9P2F8

Similarity: Contains 1 PDZ (DHR) domain

Similarity: Contains 1 Rap-GAP domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone: SIPA1L2 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SIPA1L2
		8/86 QIAGEN miScript miRNA Assays for microRNAs that regulate SIPA1L2 (see all 86):
		hsa-miR-548j hsa-miR-100* hsa-miR-642a hsa-miR-300 hsa-miR-15a hsa-miR-200a hsa-miR-371-5p hsa-miR-3622b-3p

		SwitchGear 3'UTR luciferase reporter plasmid: SIPA1L2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SIPA1L2 (see all 7) OriGene shRNA RFP: SIPA1L2 OriGene siRNA: SIPA1L2
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Gene Editing
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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SIPA1L2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SIPA1L2 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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		Search LifeMap BioReagents cell lines for SIPA1L2

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIPA1L2

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005096	GTPase activator activity	IEA	--

SIPA1L2 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for SIPA1L2:

Decreased viability with pacli

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SIPA1L2

STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

5/6 Interacting proteins for SIPA1L2 (Q9P2F8³ ENSP00000262861⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 6)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ESR2	Q92731³, ENSP00000343925⁴	I2D: score=1 STRING: ENSP00000343925
CEBPD	ENSP00000386165⁴	STRING: ENSP00000386165
NRXN1	ENSP00000385142⁴	STRING: ENSP00000385142
ORC5	ENSP00000297431⁴	STRING: ENSP00000297431
TGM2	ENSP00000355330⁴	STRING: ENSP00000355330

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0051056	regulation of small GTPase mediated signal transduction	IEA	--

SIPA1L2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SIPA1L2
Search CenterWatch for drugs/clinical trials and news about SIPA1L2 / SI1L2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SIPA1L2 gene:

NM_020808.3

Unigene Cluster for SIPA1L2:

Signal-induced proliferation-associated 1 like 2

Hs.268774 [show with all ESTs]

Unigene Representative Sequence: AY168879

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000366630(uc001hvf.3 uc001hvg.3) ENST00000308942 ENST00000494056

ENST00000495863 ENST00000486472 ENST00000262861

miRNA Products:		OriGene 3'-UTR Clone: SIPA1L2 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SIPA1L2
		8/86 QIAGEN miScript miRNA Assays for microRNAs that regulate SIPA1L2 (see all 86):
		hsa-miR-548j hsa-miR-100* hsa-miR-642a hsa-miR-300 hsa-miR-15a hsa-miR-200a hsa-miR-371-5p hsa-miR-3622b-3p

		SwitchGear 3'UTR luciferase reporter plasmid: SIPA1L2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SIPA1L2 (see all 7) OriGene shRNA RFP: SIPA1L2 OriGene siRNA: SIPA1L2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SIPA1L2

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SIPA1L2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SIPA1L2 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SIPA1L2 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SIPA1L2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SIPA1L2

Additional cDNA sequence:

AB037810.1 AK022852.1 AK026779.1 AK074212.1 AK093191.1 AY168879.1 BC006013.1 BC013119.1

BC082251.1 BC150334.1

8 DOTS entries:

DT.100769679 DT.99971419 DT.444710 DT.121342792 DT.92437519 DT.121342779 DT.40131574 DT.40282047

24/179 AceView cDNA sequences (see all 179):

AA468900 BE467827 AA985653 AW612226 AW513378 AA035016 BC082251 AI912726

CB242802 AI142899 BM971808 AW770804 AI492846 AW078999 AJ713536 BU160440

AI492858 AI291490 AA337530 AI091118 AI703130 BE927860 AI401246 AA716216

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for SIPA1L2 About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14a	·	14b	^	15a	·	15b	^	16	^	17a	·	17b	^	18	^	19	^	20a	·	20b	^	21a	·	21b	^
SP1:															-																																-		-
SP2:																																											-				-		-
SP3:																															-
SP4:																																											-
SP5:

ExUns:	22a	·	22b	·	22c
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for SIPA1L2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SIPA1L2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGAACAAATA

About this image

SIPA1L2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 4 LifeMap Cells

Name

Category

PureStem™ epithelial progenitor E164 (Embryonic Progenitor Cell)

Intermediate Mesoderm, Kidney

PureStem™ mesenchymal progenitor 7PEND24 (Embryonic Progenitor Cell)

Cartilage, Neural Crest

PureStem™ progenitor T36 (Embryonic Progenitor Cell)

PureStem™ progenitor W8 (Embryonic Progenitor Cell)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SIPA1L2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SIPA1L2

SOURCE GeneReport for Unigene cluster: Hs.268774

SABiosciences Custom PCR Arrays for SIPA1L2

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIPA1L2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for SIPA1L2 gene from 6/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	SIPA1L2¹	signal-induced proliferation-associated 1 like 2	77.91(n) 86.89(a)		421523 XM_419564.3 XP_419564.2
lizard (Anolis carolinensis)	Reptilia	SIPA1L2⁶	--	85(a)	1 ↔ 1	1(221078054-221154075)
African clawed frog (Xenopus laevis)	Amphibia	Xl.19940²	Xenopus laevis transcribed sequences	74.29(n)		BJ619439.1
zebrafish (Danio rerio)	Actinopterygii	im:7137555¹	im:7137555	64.69(n) 64.9(a)		497350 NM_001201559.1 NP_001188488.1
mosquito (Anopheles gambiae)	Insecta	AgaP_AGAP008488¹	AGAP008488-PA	56.1(n) 57.57(a)		1277490 XM_316956.4 XP_316956.4
worm (Caenorhabditis elegans)	Secernentea	T27F2.2⁶	--	34(a)	1 → many	V(11631426-11637273)

ENSEMBL Gene Tree for SIPA1L2 (if available)
TreeFam Gene Tree for SIPA1L2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SIPA1L2 gene

SIPA1L3² SIPA1L1² SIPA1² RAP1GAP² GARNL3² RAP1GAP2²

3 SIMAP similar genes for SIPA1L2 using alignment to 2 protein entries: SI1L2_HUMAN (see all proteins):

SIPA1L1 SIPA1L3 SIPA1

SIPA1L2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs181396720^1,2		--	232533335(+)	`CACCCA/GCCTTG`	1	--	int¹		0	--	--	--	--
rs186918597^1,2		--	232533405(+)	`CTTGCA/GTAAAT`	1	--	int¹		0	--	--	--	--
rs190466375^1,2		--	232533413(+)	`AATTAC/TTTCAC`	1	--	int¹		0	--	--	--	--
rs112349113^1,2		--	232533452(+)	`GGGAAC/TCCCAC`	1	--	int¹		1		CSA	2
rs139762387^1,2		--	232533459(+)	`CCACCG/TCCTAC`	1	--	int¹		0	--	--	--	--
rs2356927^1,2	C,F,A,H,	--	232533667(+)	`GACTGT/CTGACA`	1	--	int¹		8		NA WA EA	370
rs183042962^1,2		--	232533832(+)	`GTCGTC/TAGAAT`	1	--	ut3¹		0	--	--	--	--
rs141629795^1,2		--	232533854(+)	`CTTCTC/TGGTCT`	1	--	ut3¹		0	--	--	--	--
rs150501002^1,2		--	232534062(+)	`CACAGC/GACACA`	1	--	ut3¹		0	--	--	--	--
rs116054596^1,2	C,F,	--	232534109(+)	`TCTTTC/ACAGCA`	1	--	ut3¹		1		WA	118

HapMap Linkage Disequilibrium report for SIPA1L2 (232533711 - 232697304 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SIPA1L2
1 CNV: 8348
1 Indel: 58373

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SIPA1L2

DNA2.0 Custom Variant and Variant Library Synthesis for SIPA1L2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SIPA1L2 for disorders About MalaCards

SIPA1L2 for disorders About GeneDecksing

OMIM gene information: 611609 OMIM disorders: --

Human Genome Epidemiology (HuGE) Navigator: SIPA1L2 (2 documents)

Export disorders for SIPA1L2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SIPA1L2 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with SIPA1L2)

Utopia: connect your pdf to the dynamic
world of online information

The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)^{1, 2} Nagase T.... Ohara O. (2000)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Association of IFIH1 and other autoimmunity risk alle les with selective IgA deficiency. (PubMed id 20694011)¹ Ferreira R.C....HammarstrAPm L. (2010)
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)² Olsen J.V....Mann M. (2010)
Generalist genes analysis of DNA markers associated w ith mathematical ability and disability reveals shared influence across ages an d abilities. (PubMed id 20602751)¹ Docherty S.J....Plomin R. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

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Aliases
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Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 57568	HGNC: 23800	AceView: SIPA1L2	Ensembl:ENSG00000116991	euGenes: HUgn57568
ECgene: SIPA1L2	H-InvDB: SIPA1L2

(According to HUGE)
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HUGE: KIAA1389

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SIPA1L2	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for SIPA1L2	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for SIPA1L2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for SIPA1L2 gene:
Search GeneIP for patents involving SIPA1L2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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SIPA1L2 Gene

signal-induced proliferation-associated 1 like 2

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SIPA1L2 Gene

signal-induced proliferation-associated 1 like 2

Aliasesfor SIPA1L2 gene

Summariesfor SIPA1L2 gene

Genomic Viewsfor SIPA1L2 gene

Proteinsfor SIPA1L2 gene

Protein Domains /Familiesfor SIPA1L2 gene

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Expression for SIPA1L2 gene

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External Searches for SIPA1L2 gene

Genome Databases showing SIPA1L2 gene

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Specialized Databases showing SIPA1L2 gene

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Aliases
for SIPA1L2 gene

Summaries
for SIPA1L2 gene

Genomic Views
for SIPA1L2 gene

Proteins
for SIPA1L2 gene

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Families
for SIPA1L2 gene

Function
for SIPA1L2 gene

Pathways & Interactions
for SIPA1L2 gene

Drugs & Compounds
for SIPA1L2 gene

Transcripts
for SIPA1L2 gene

Expression
for SIPA1L2 gene

Orthologs
for SIPA1L2 gene

Paralogs
for SIPA1L2 gene

Genomic Variants
for SIPA1L2 gene

Disorders / Diseases
for SIPA1L2 gene

Publications
for SIPA1L2 gene

Intellectual Property
for SIPA1L2 gene

Products
for SIPA1L2 gene