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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SIPA1L1 Gene

protein-coding   GIFtS: 52
GCID: GC14P071787

Signal-Induced Proliferation-Associated 1 Like 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Signal-Induced Proliferation-Associated 1 Like 11 2     Signal-Induced Proliferation-Associated 1-Like Protein 12
High-Risk Human Papilloma Viruses E6 Oncoproteins Targeted Protein 12 3     KIAA04403
E6TP12 3     E6-Targeted Protein 13
SIPA1-Like Protein 12 3     

External Ids:    HGNC: 202841   Entrez Gene: 260372   Ensembl: ENSG000001975557   UniProtKB: O431663   

Export aliases for SIPA1L1 gene to outside databases

Previous GC identifers: GC14P069987 GC14P069988 GC14P071065 GC14P071996 GC14P052162


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SIPA1L1 Gene: 
SIPA1L1 (signal-induced proliferation-associated 1 like 1) is a protein-coding gene. Diseases associated with SIPA1L1 include papilloma, and neuronitis. GO annotations related to this gene include ephrin receptor binding and molecular_function. An important paralog of this gene is SIPA1.

UniProtKB/Swiss-Prot: SI1L1_HUMAN, O43166
Function: Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits
DLG4 to F-actin. Contributes to the regulation of dendritic spine morphogenesis (By similarity)

Gene Wiki entry for SIPA1L1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NT_026437.12  NC_018925.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SIPA1L1 gene promoter:
         MEF-2   CUTL1   MEF-2A   S8   IRF-7A   FOXO1a   aMEF-2   En-1   FOXO1   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSIPA1L1 promoter sequence
   Search SABiosciences Chromatin IP Primers for SIPA1L1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SIPA1L1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q24.2   Ensembl cytogenetic band:  14q24.2   HGNC cytogenetic band: 14q24.1

SIPA1L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SIPA1L1 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P071787:  view genomic region     (about GC identifiers)

Start:
71,787,166 bp from pter      End:
72,207,946 bp from pter
Size:
420,781 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SI1L1_HUMAN, O43166 (See protein sequence)
Recommended Name: Signal-induced proliferation-associated 1-like protein 1  
Size: 1804 amino acids; 200029 Da
Subunit: Interacts with DLG4, PDLIM5, PDLIM7 and LZTS3. Interacts with the actin cytoskeleton (By similarity).
Interacts (via PDZ domain) with EPHA4 (via PDZ motif); controls neuronal morphology through regulation of the
RAP1 (RAP1A or RAP1B) and RAP2 (RAP2A, RAP2B or RAP2C) GTPases. Interacts with HPV E6
Subcellular location: Cytoplasm, cytoskeleton (By similarity). Cell junction, synapse, postsynaptic cell membrane,
postsynaptic density (By similarity). Cell junction, synapse, synaptosome (By similarity). Note=Associated with
the actin cytoskeleton. Detected at synapses and dendritic spines of cultured hippocampal neurons (By similarity)
Sequence caution: Sequence=BAA23712.2; Type=Erroneous initiation;
Secondary accessions: O95321 Q9UDU4 Q9UNU4
Alternative splicing: 2 isoforms:  O43166-1   O43166-2   

Explore the universe of human proteins at neXtProt for SIPA1L1: NX_O43166

Explore proteomics data for SIPA1L1 at MOPED 

Post-translational modifications:

  • UniProtKB: Ubiquitinated and degraded by the SCF(BTRC) following phosphorylation by PLK2 (By similarity)
  • UniProtKB: Phosphorylated at Ser-1349 by CDK5, creating a docking site for the POLO box domains of PLK2. Subsequently, PLK2
    binds and phosphorylates SIPA1L1, leading to ubiquitination and degradation by the proteasome (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O43166

  • SIPA1L1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SIPA1L1 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001271174.1  NP_001271175.1  NP_001271176.1  NP_056371.1  

    ENSEMBL proteins: 
     ENSP00000452080   ENSP00000370630   ENSP00000450832   ENSP00000351352   ENSP00000440682  
     ENSP00000452450  

    Human Recombinant Protein Products for SIPA1L1: 
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    Cloud-Clone Corp. Proteins for SIPA1L1 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005737cytoplasm IEA--
    GO:0005886plasma membrane IEA--
    GO:0014069postsynaptic density ISS--
    GO:0030054cell junction IEA--

    SIPA1L1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR001478 PDZ
     IPR000331 Rap_GAP_dom
     IPR021818 DUF3401

    Graphical View of Domain Structure for InterPro Entry O43166

    ProtoNet protein and cluster: O43166

    1 Blocks protein domain: IPB000331 Rap/ran-GAP

    UniProtKB/Swiss-Prot: SI1L1_HUMAN, O43166
    Similarity: Contains 1 PDZ (DHR) domain
    Similarity: Contains 1 Rap-GAP domain


    SIPA1L1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SI1L1_HUMAN, O43166
    Function: Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits
    DLG4 to F-actin. Contributes to the regulation of dendritic spine morphogenesis (By similarity)

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005096GTPase activator activity IEA--
    GO:0005515protein binding ----
    GO:0046875ephrin receptor binding IEA--
         
    SIPA1L1 for ontologies           About GeneDecksing


    Animal Models:
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SIPA1L1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/12 Interacting proteins for SIPA1L1 (O431662, 3 ENSP000003513524) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DLG4P783522, 3MINT-8305428 I2D: score=2 
    SFNP319472, 3MINT-3975301 I2D: score=2 
    CEBPEQ157443, ENSP000002065134I2D: score=3 STRING: ENSP00000206513
    NRXN1Q9ULB13, ENSP000003851424I2D: score=3 STRING: ENSP00000385142
    USP11P517843, ENSP000002183484I2D: score=2 STRING: ENSP00000218348
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0031532actin cytoskeleton reorganization ISS--
    GO:0032317regulation of Rap GTPase activity ISS--
    GO:0032861activation of Rap GTPase activity ISS--
    GO:0048013ephrin receptor signaling pathway ISS--

    SIPA1L1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SIPA1L1 (SI1L1)

    Search CenterWatch for drugs/clinical trials and news about SIPA1L1 / SI1L1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SIPA1L1 gene (4 alternative transcripts): 
    NM_001284245.1  NM_001284246.1  NM_001284247.1  NM_015556.2  

    Unigene Cluster for SIPA1L1:

    Signal-induced proliferation-associated 1 like 1
    Hs.654657  [show with all ESTs]
    Unigene Representative Sequence: AK122930
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000553453 ENST00000555989 ENST00000556408 ENST00000554126 ENST00000556780
    ENST00000554362 ENST00000555652 ENST00000557151 ENST00000557469 ENST00000557712(uc001xmr.1)
    ENST00000381232(uc001xmt.3) ENST00000555818(uc001xms.3 uc001xmv.3)
    ENST00000358550(uc001xmu.3) ENST00000537413(uc010ttm.2) ENST00000555066
    ENST00000554960 ENST00000554874 ENST00000556959
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    Additional mRNA sequence: 

    AB007900.2 AF090989.1 AF090990.1 AK094532.1 AK122930.1 AK302650.1 BC033950.2 BC146777.1 
    CR936651.1 

    18 DOTS entries:

    DT.100649905  DT.92430773  DT.100649906  DT.101974659  DT.91732500  DT.70104680  DT.40108074  DT.100706264 
    DT.120772965  DT.405444  DT.95081724  DT.120772948  DT.120773003  DT.100653028  DT.120772934  DT.40106672 
    DT.86844822  DT.95150548 

    24/189 AceView cDNA sequences (see all 189):

    AF090990 AI582730 AI498104 AL707661 BM987928 BF890751 BQ927153 BQ019460 
    CR612092 AL119011 BU622384 AF090989 BP337149 AK122930 BE272281 AW296953 
    BM679416 BQ015905 BQ014925 BM782153 AI057021 BX457320 BU956798 NM_015556 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for SIPA1L1 (see all 11)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15a · 15b · 15c ^ 16a · 16b ^ 17a · 17b ^ 18 ^ 19 ^ 20a ·
    SP1:                                                                                                                                                            
    SP2:                                                                                                                    -                                       
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                            -     -                                                         

    ExUns: 20b ^ 21 ^ 22
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for SIPA1L1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SIPA1L1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCTAGGGAA
    SIPA1L1 Expression
    About this image


    See SIPA1L1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SIPA1L1

    SOURCE GeneReport for Unigene cluster: Hs.654657

    UniProtKB/Swiss-Prot: SI1L1_HUMAN, O43166
    Tissue specificity: Widely expressed

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for SIPA1L1 gene from 5/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sipa1l11 , 5 signal-induced proliferation-associated 1 like 11, 5 88.59(n)1
    95.85(a)1
      12 (38.14 cM)5
    2176921  NM_172579.31  NP_766167.21 
     821700165 
    chicken
    (Gallus gallus)
    Aves SIPA1L11 signal-induced proliferation-associated 1 like 1 81.17(n)
    90.43(a)
      423255  NM_001199690.1  NP_001186619.1 
    lizard
    (Anolis carolinensis)
    Reptilia SIPA1L16
    Uncharacterized protein
    87(a)
    1 ↔ 1
    1(37958536-38135119)
    African clawed frog
    (Xenopus laevis)
    Amphibia BQ399465.12   -- 74.05(n)    BQ399465.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CD594418.12   -- 73.93(n)   321066  CD594418.1 


    ENSEMBL Gene Tree for SIPA1L1 (if available)
    TreeFam Gene Tree for SIPA1L1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SIPA1L1 gene
    SIPA12  SIPA1L32  RAP1GAP2  SIPA1L22  RAP1GAP22  GARNL32  
    5 SIMAP similar genes for SIPA1L1 using alignment to 6 protein entries:     SI1L1_HUMAN (see all proteins):
    DKFZp686G1344    SIPA1L2    SIPA1L3    RAP1GAP    SIPA1

    SIPA1L1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3694 SNPs in SIPA1L1 are shown (see all 3694)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0355494
    A breast cancer sample4--see VAR_0355492 E D mis40--------
    rs764169681,2
    C,F--52983993(+) ATTTTT/CATTTT 1 -- us2k12Minor allele frequency- C:0.06CSA WA 120
    rs1842026841,2
    --52984170(+) TCTTAC/TTAATT 1 -- us2k10--------
    rs1142908621,2
    C,F--52984179(+) TTTGTA/GAGGAG 1 -- us2k11Minor allele frequency- G:0.01WA 118
    rs1127580731,2
    C--52984285(+) AAAAAT/-TTTTT 1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs1170260571,2
    F--52984631(+) GCTCCG/ACCTCC 1 -- us2k11Minor allele frequency- A:0.03NA 120
    rs1410582401,2
    --52984647(+) TCAAGC/TGATTT 1 -- us2k10--------
    rs1449190041,2
    --52984704(+) TGTACC/TGGCTA 1 -- us2k10--------
    rs1475751531,2
    --52984786(+) TTCAGC/TACTCC 1 -- us2k10--------
    rs1158801561,2
    F--52984992(+) AGACTA/GCATGA 1 -- us2k11Minor allele frequency- G:0.01WA 118

    HapMap Linkage Disequilibrium report for SIPA1L1 (71787166 - 72037166 bp, first 250kb of SIPA1L1)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SIPA1L1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv85474CNV Loss16902084
    nsv84708CNV Loss16902084
    esv32876CNV Gain17666407

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for SIPA1L1:    About MalaCards
    papilloma    neuronitis


    SIPA1L1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SIPA1L1

    Export disorders for SIPA1L1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SIPA1L1 gene, integrated from 9 sources (see all 34):
    (articles sorted by number of sources associating them with SIPA1L1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation. (PubMed id 9858596)1, 2, 3, 9 Gao Q.... Band V. (1999)
    2. Common variants in 22 loci are associated with QRS du ration and cardiac ventricular conduction. (PubMed id 21076409)1, 4 Sotoodehnia N....Arking D.E. (2010)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)1, 2 Heilig R.... Weissenbach J. (2003)
    5. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
    6. Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9455477)1, 2 Ishikawa K....Ohara O. (1997)
    7. Analysis of the roles of E6 binding to E6TP1 and nuclear localization in the human papillomavirus type 31 life cycle. (PubMed id 16999984)1, 9 Lee C....Laimins L.A. (2007)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    10. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26037 HGNC: 20284 AceView: SIPA1L1 Ensembl:ENSG00000197555 euGenes: HUgn26037
    ECgene: SIPA1L1 H-InvDB: SIPA1L1

    (According to HUGE)
    About This Section
    HUGE: KIAA0440

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SIPA1L1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SIPA1L1 gene:
    Search GeneIP for patents involving SIPA1L1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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