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Aliases for SIGLECL1 Gene

Aliases for SIGLECL1 Gene

  • SIGLEC Family Like 1 2 3
  • Sialic Acid Binding Ig-Like Lectin, Pseudogene 7 2 3
  • C19orf75 3 4
  • Sialic Acid Binding Ig-Like Lectin 23, Pseudogene 2
  • Chromosome 19 Open Reading Frame 75 2
  • SIGLEC Family-Like Protein 1 3
  • SIGLEC23P 3
  • SIGLECP7 3
  • SIGLEC12 6
  • S2V 6
  • SLG 6

External Ids for SIGLECL1 Gene

Previous HGNC Symbols for SIGLECL1 Gene

  • C19orf75
  • SIGLEC23P
  • SIGLECP7

Previous GeneCards Identifiers for SIGLECL1 Gene

  • GC19M052625
  • GC19M052355
  • GC19M056670
  • GC19M056686
  • GC19P051761

Summaries for SIGLECL1 Gene

GeneCards Summary for SIGLECL1 Gene

SIGLECL1 (SIGLEC Family Like 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SIGLECL1 Gene

Genomics for SIGLECL1 Gene

Genomic Location for SIGLECL1 Gene

Start:
51,246,348 bp from pter
End:
51,269,330 bp from pter
Size:
22,983 bases
Orientation:
Plus strand

Genomic View for SIGLECL1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SIGLECL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SIGLECL1 Gene

No data available for Regulatory Elements for SIGLECL1 Gene

Proteins for SIGLECL1 Gene

  • Protein details for SIGLECL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N7X8-SIGL1_HUMAN
    Recommended name:
    SIGLEC family-like protein 1
    Protein Accession:
    Q8N7X8
    Secondary Accessions:

    Protein attributes for SIGLECL1 Gene

    Size:
    197 amino acids
    Molecular mass:
    21283 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SIGLECL1 Gene

Proteomics data for SIGLECL1 Gene at MOPED

Post-translational modifications for SIGLECL1 Gene

No Post-translational modifications

Other Protein References for SIGLECL1 Gene

No data available for DME Specific Peptides for SIGLECL1 Gene

Domains for SIGLECL1 Gene

Protein Domains for SIGLECL1 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SIGLECL1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SIGLECL1 Gene

Function for SIGLECL1 Gene

Gene Ontology (GO) - Molecular Function for SIGLECL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with SIGLECL1: view

Phenotypes for SIGLECL1 Gene

GenomeRNAi human phenotypes for SIGLECL1:
genes like me logo Genes that share phenotypes with SIGLECL1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SIGLECL1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SIGLECL1 Gene

Localization for SIGLECL1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SIGLECL1 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SIGLECL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SIGLECL1: view

No data available for Subcellular locations from COMPARTMENTS for SIGLECL1 Gene

Pathways for SIGLECL1 Gene

SuperPathways for SIGLECL1 Gene

No Data Available

Interacting Proteins for SIGLECL1 Gene

Gene Ontology (GO) - Biological Process for SIGLECL1 Gene

None

No data available for Pathways by source for SIGLECL1 Gene

Transcripts for SIGLECL1 Gene

mRNA/cDNA for SIGLECL1 Gene

Unigene Clusters for SIGLECL1 Gene

SIGLEC family like 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SIGLECL1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SIGLECL1 Gene

No ASD Table

Relevant External Links for SIGLECL1 Gene

GeneLoc Exon Structure for
SIGLECL1
ECgene alternative splicing isoforms for
SIGLECL1

Expression for SIGLECL1 Gene

mRNA expression in normal human tissues for SIGLECL1 Gene

mRNA differential expression in normal tissues according to GTEx for SIGLECL1 Gene

This gene is overexpressed in Testis (51.8).

Protein differential expression in normal tissues for SIGLECL1 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for SIGLECL1 Gene

SOURCE GeneReport for Unigene cluster for SIGLECL1 Gene Hs.381087

genes like me logo Genes that share expressions with SIGLECL1: view

Expression partners for SIGLECL1 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SIGLECL1 Gene

Orthologs for SIGLECL1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SIGLECL1 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia SIGLECL1 35
  • 80.95 (n)
  • 67.72 (a)
SIGLECL1 36
  • 67 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm2511 35
  • 71.43 (n)
  • 59.79 (a)
4931406B18Rik 36
  • 21 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia SIGLECL1 35
  • 99.15 (n)
  • 98.48 (a)
SIGLECL1 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Siglecl1 35
  • 70.68 (n)
  • 57.59 (a)
cow
(Bos Taurus)
Mammalia SIGLECL1 36
  • 61 (a)
OneToOne
Species with no ortholog for SIGLECL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SIGLECL1 Gene

ENSEMBL:
Gene Tree for SIGLECL1 (if available)
TreeFam:
Gene Tree for SIGLECL1 (if available)

Paralogs for SIGLECL1 Gene

Selected SIMAP similar genes for SIGLECL1 Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for SIGLECL1 Gene

genes like me logo Genes that share paralogs with SIGLECL1: view

No data available for Paralogs for SIGLECL1 Gene

Variants for SIGLECL1 Gene

Sequence variations from dbSNP and Humsavar for SIGLECL1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs166653 -- 51,256,479(+) gcatg(A/G)aagca upstream-variant-2KB, intron-variant
rs175402 -- 51,255,258(-) cttga(A/G)acagg intron-variant
rs273619 -- 51,256,682(+) aaaaa(C/T)ggtaa upstream-variant-2KB, intron-variant
rs273641 -- 51,252,410(-) TTTAA(C/G)TACAA intron-variant
rs273642 -- 51,252,343(-) CGTCA(G/T)GCACC intron-variant

Relevant External Links for SIGLECL1 Gene

HapMap Linkage Disequilibrium report
SIGLECL1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SIGLECL1 Gene

Disorders for SIGLECL1 Gene

No disorders were found for SIGLECL1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SIGLECL1 Gene

Publications for SIGLECL1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. (PMID: 23362303) Wu J.H. … Mozaffarian D. (Circ Cardiovasc Genet 2013) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. A second uniquely human mutation affecting sialic acid biology. (PMID: 11546777) Angata T. … Varki A. (J. Biol. Chem. 2001) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SIGLECL1 Gene

Sources for SIGLECL1 Gene

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