SIGLEC6 Gene
protein-coding GIFtS: 54
GCID: GC19M052020
|
|
sialic acid binding Ig-like lectin 6
(Previous symbols: CD33L, CD33L1)
| |
Aliases
for SIGLEC6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Sialic Acid Binding Ig-Like Lectin 61 2 | | SIGLEC-61 | | CD33L1 2 3 5 | | CD33L22 | | CD33L11 2 3 5 | | CDW3272 | | OBBP12 3 5 | | Sialic Acid-Binding Ig-Like Lectin 62 | | CD3271 2 | | CDw3273 | | OB-BP11 3 | | Siglec-63 | | Obesity-Binding Protein 12 3 | | CD327 Antigen3 | | CD33 Antigen-Like 12 3 | | |
| External Ids: | HGNC: 108751 | Entrez Gene: 9462 | Ensembl: ENSG000001054927 | OMIM: 6044055 | UniProtKB: O436993 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n338910 | |
Export aliases for SIGLEC6 gene to outside databasesPrevious GC identifers: GC19M052651 GC19M052382 GC19M056696 GC19M056712 GC19M048355
Summaries
for SIGLEC6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: SIGL6_HUMAN, O43699Function: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linkedsialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cellsurface
|
Genomic Views
for SIGLEC6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SIGLEC6 gene promoter:
USF1 NRSF form 1 RelA LUN-1 Ik-3 NF-kappaB NRSF form 2 GATA-1 USF-1 NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SIGLEC6
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SIGLEC6 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.3 Ensembl cytogenetic band: 19q13.41 HGNC cytogenetic band: 19q13.3SIGLEC6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M052020: view genomic region
(about GC identifiers)
Start:
|
52,022,779 bp from pter |
End:
|
52,035,110 bp from pter |
Size:
|
12,332 bases |
Orientation:
|
minus strand |
|
Proteins
for SIGLEC6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SIGL6_HUMAN, O43699 (See
protein sequence)Recommended Name: Sialic acid-binding Ig-like lectin 6 precursor Size: 453 amino acids; 49913 Da
Subunit: Interacts with LEP
Subcellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein
Subcellular location: Isoform 2: Secreted
Sequence caution: Sequence=AAB70702.1; Type=Erroneous initiation; Sequence=AAH35359.2; Type=Erroneous initiation;Sequence=AAI40799.1; Type=Erroneous initiation; Sequence=BAA24983.1; Type=Erroneous initiation; Sequence=BAA24984.1;Type=Erroneous initiation;
Secondary accessions: A8MV71 B2RTS8 C9JBE5 F8WA78 O15388 O43700Alternative splicing: 6 isoforms: O43699-1 O43699-2 O43699-3 O43699-4 O43699-5 O43699-6 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SIGLEC6: NX_O43699
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43699
SIGLEC6 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins (6 alternative transcripts):
NP_001171018.1 NP_001171019.1 NP_001171020.1 NP_001236.4 NP_942142.3 NP_942143.3
ENSEMBL proteins: ENSP00000344064 ENSP00000401502 ENSP00000353071 ENSP00000410679 ENSP00000345907 ENSP00000393601 ENSP00000375674
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
SIGLEC6 for ontologies About GeneDecksing
SIGLEC6 Antibody Products:
Assay Products for SIGLEC6: |
Protein
Domains /
Families
for SIGLEC6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SIGLEC6 for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry O43699ProtoNet protein and cluster: O43699 1 Blocks protein family: IPB003598 Immunoglobulin C-2 type
UniProtKB/Swiss-Prot: SIGL6_HUMAN, O43699Domain: Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif(ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2domain of several SH2-containing phosphatasesSimilarity: Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) familySimilarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domainsSimilarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain |
Function
for SIGLEC6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SIGL6_HUMAN, O43699Function: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linkedsialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cellsurface Genatlas biochemistry entry for SIGLEC6:sialic acid binding Ig-like lectin 6,expressed in placenta,spleen,peripheral blood leukocytes and smallintestine,mediating cell-cell recognition,also binding leptin and potentially modulator of leptin levels,sialoadhesinfamily,Ig superfamily
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SIGLEC6 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SIGLEC6 (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for SIGLEC6 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SIGLEC6 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIGLEC6 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0030246 | carbohydrate binding |
-- | -- |
SIGLEC6 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SIGLEC6:
|
Pathways & Interactions
for SIGLEC6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SIGLEC6
2 Interacting proteins for SIGLEC6 (O436993) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
SIGLEC6 for ontologies About GeneDecksing
|
Drugs & Compounds
for SIGLEC6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SIGLEC6
Search CenterWatch for drugs/clinical trials and news about SIGLEC6 / SIGL6
|
Transcripts
for SIGLEC6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SIGLEC6 gene (6 alternative transcripts): NM_001177547.1 NM_001177548.1 NM_001177549.1 NM_001245.5 NM_198845.4 NM_198846.4 Unigene Cluster for SIGLEC6: Sialic acid binding Ig-like lectin 6 Hs.720304 [show with all ESTs]Unigene Representative Sequence: NM_00124510 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000346477 ENST00000425629 ENST00000359982 ENST00000436458 ENST00000343300
ENST00000474054 ENST00000496422(uc010epa.2 uc010epb.2) ENST00000489837
ENST00000426829 ENST00000391797(uc002pwy.3 uc002pwz.3 uc010ydb.2 uc010ydc.2 uc002pxa.3 uc010eoz.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SIGLEC6 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SIGLEC6 (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 6): SIGLEC6 (NM_198845) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SIGLEC6 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SIGLEC6 |
Additional cDNA sequence: AK300170.1 AK300182.1 AK308174.1 AK309903.1 BC140798.1 D86359.1 U71382.1 6 DOTS entries: DT.40234980 DT.100743108 DT.443097 DT.91744472 DT.100832961 DT.95364990 24/48 AceView cDNA sequences (see all 48): AV714551 NM_198846 CA495365 NM_198845 BC035359 CR600025 BX114837 NM_001245 CR614233 BG623595 CB992745 AL543769 CF529873 AL542471 BG623874 BF436016 CB961761 AL542696 BX334419 N40753 BX369880 CB992313 D86359 N41556
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SIGLEC6 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | |
| SP4: | | | | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SIGLEC6
|
Expression
for SIGLEC6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SIGLEC6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACCTAATTTA
About this image
Genevestigator expression for SIGLEC6
SOURCE GeneReport for Unigene cluster: Hs.720304
UniProtKB/Swiss-Prot: SIGL6_HUMAN, O43699Tissue specificity: Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels inspleen, peripheral blood leukocytes (predominantly B-cells) and small intestine
SABiosciences Custom PCR Arrays for SIGLEC6
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SIGLEC6
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIGLEC6 |
Orthologs
for SIGLEC6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for SIGLEC6 gene from 2/5 species (see all 5) About this table
ENSEMBL Gene Tree for SIGLEC6 (if available)
TreeFam Gene Tree for SIGLEC6 (if available) |
Paralogs
for SIGLEC6 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SIGLEC6 gene
- CD332 SIGLEC17P2 SIGLEC82 SIGLEC52 SIGLEC162 SIGLEC112 SIGLEC142 SIGLEC122
- MAG2 SIGLEC102 SIGLEC72 SIGLEC92
10 SIMAP similar genes for SIGLEC6 using alignment to 1 protein entry: SIGL6_HUMAN:SIGLEC14 SIGLEC12 SIGLEC7 SIGLEC9 SIGLEC11 SIGLEC10
SIGLEC5 SIGLEC8 CD33 SIGLEC16
SIGLEC6 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for SIGLEC6
PGOHUM00000234740 PGOHUM00000250613
|
Genomic Variants
for SIGLEC6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SIGLEC6 (52022779 - 52035110 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SIGLEC6
1 CNV: 4085 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SIGLEC6 |
|
Disorders
/ Diseases
for SIGLEC6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SIGLEC6 for disorders About GeneDecksing
OMIM gene information: 604405
OMIM disorders: --
6  diseases for SIGLEC6: About MalaCardspre-eclampsia severe pre-eclampsia obesity eclampsia
hepatitis b hepatitis
Human Genome Epidemiology (HuGE) Navigator: SIGLEC6 (1 document)
Export disorders for SIGLEC6 gene to outside databases
|
Publications
for SIGLEC6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SIGLEC6 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with SIGLEC6) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning of a novel gene similar to myeloid antigen CD33 and its specific expression in placenta. (PubMed id 9465907)1, 2, 3, 9 Takei Y.... Nakamura Y. (1997)
- OB-BP1/Siglec-6. A leptin- and sialic acid-binding protein of the immunoglobulin superfamily. (PubMed id 10428856)1, 2 Patel N.... Kastelein R.A. (1999)
- Severe preeclampsia-related changes in gene expression at the maternal-fetal interface include sialic acid-binding immunoglobulin-like lectin-6 and pappalysin-2. (PubMed id 18818296)1, 9 Winn V.D....Fisher S.J. (2009)
- Glycodelin-A protein interacts with Siglec-6 protein to suppress trophoblast invasiveness by down-regulating extracellular signal-re gulated kinase (ERK)/c-Jun signaling pathway. (PubMed id 21880722)1 Lam K.K....Yeung W.S. (2011)
- New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- Human-specific expression of Siglec-6 in the placenta. (PubMed id 17580316)1 Brinkman-Van der Linden E.C....Varki N. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
|
External Searches for SIGLEC6 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SIGLEC6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SIGLEC6 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SIGLEC6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SIGLEC6 | Pharmacogenomics, SNPs, Pathways | | Functional Glycomics Gateway - Glycan Binding | http://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Itlect_273 |
|
| | |
About This Section
| Patent Information for SIGLEC6 gene:
Search GeneIP for patents involving SIGLEC6
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SIGLEC6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SIGLEC6 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SIGLEC6 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SIGLEC6 | | | OriGene Protein Over-expression Lysate for SIGLEC6 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SIGLEC6 | | OriGene 3'-UTR Clone for SIGLEC6 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SIGLEC6 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SIGLEC6 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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 | | | SIGLEC6 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIGLEC6 |
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