SIGLEC12 Gene
protein-coding GIFtS: 48
GCID: GC19M051994
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sialic acid binding Ig-like lectin 12 (gene/pseudogene)(Previous names: SIGLEC-like 1, sialic acid binding Ig-like lectin 12 )
(Previous symbol: SIGLECL1)
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Aliases
for SIGLEC12 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Sialic Acid Binding Ig-Like Lectin 12 (Gene/Pseudogene)1 2 | | Siglec-121 3 | | SIGLECL11 2 3 5 | | Siglec-L11 3 | | SLG1 2 3 5 | | Sialic Acid-Binding Ig-Like Lectin-Like 12 3 | | S2V1 2 | | Sialic Acid Binding Ig-Like Lectin 121 | | Siglec-XII1 2 | | Sialic Acid-Binding Ig-Like Lectin 122 | | SIGLEC-Like 11 2 | | |
Export aliases for SIGLEC12 gene to outside databasesPrevious GC identifers: GC19M056687 GC19M051913 |
Summaries
for SIGLEC12 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SIGLEC12:
Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to theimmunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialicacid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily ofSIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed bytwo C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encodedprotein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containingprotein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negativeregulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster withother SIGLEC3-like genes on 19q13.4. Alternatively spliced transcript variants encoding distinct isoforms have beendescribed for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: SIG12_HUMAN, Q96PQ1Function: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognitionsite may be masked by cis interactions with sialic acids on the same cell surface
Gene Wiki entry for SIGLEC12 (Sialic acid-binding Ig-like lectin 12)
|
Genomic Views
for SIGLEC12 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SIGLEC12 gene promoter:
MEF-2A MEF-2 ARP-1 aMEF-2 TGIF
Other transcription factors
Search SABiosciences Chromatin IP Primers for SIGLEC12
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SIGLEC12 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.4 Ensembl cytogenetic band: 19q13.41 HGNC cytogenetic band: 19q13.41SIGLEC12 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M051994: view genomic region
(about GC identifiers)
Start:
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51,994,613 bp from pter |
End:
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52,005,043 bp from pter |
Size:
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10,431 bases |
Orientation:
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minus strand |
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Proteins
for SIGLEC12 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SIG12_HUMAN, Q96PQ1 (See
protein sequence)Recommended Name: Sialic acid-binding Ig-like lectin 12 precursor Size: 595 amino acids; 64984 Da
Subcellular location: Membrane; Single-pass type I membrane protein
Secondary accessions: Q8IYH7Alternative splicing: 2 isoforms: Q96PQ1-1 Q96PQ1-2 Explore the universe of human proteins at neXtProt for SIGLEC12: NX_Q96PQ1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96PQ1
SIGLEC12 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins (2 alternative transcripts):
NP_201586.1 NP_443729.1
ENSEMBL proteins: ENSP00000291707
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
SIGLEC12 for ontologies About GeneDecksing
SIGLEC12 Antibody Products:
Assay Products for SIGLEC12: |
Protein
Domains /
Families
for SIGLEC12 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SIGLEC12 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q96PQ1ProtoNet protein and cluster: Q96PQ1 2 Blocks protein families: IPB003598 Immunoglobulin C-2 type IPB013106 Immunoglobulin V-set
UniProtKB/Swiss-Prot: SIG12_HUMAN, Q96PQ1Domain: Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif(ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2domain of several SH2-containing phosphatasesSimilarity: Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) familySimilarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domainsSimilarity: Contains 2 Ig-like V-type (immunoglobulin-like) domains |
Function
for SIGLEC12 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SIG12_HUMAN, Q96PQ1Function: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognitionsite may be masked by cis interactions with sialic acids on the same cell surface
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SIGLEC12 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SIGLEC12 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for SIGLEC12 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SIGLEC12 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIGLEC12 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0030246 | carbohydrate binding |
-- | -- |
SIGLEC12 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SIGLEC12:
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Pathways & Interactions
for SIGLEC12 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SIGLEC12
3 Interacting proteins for SIGLEC12 (Q96PQ13) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007155 | cell adhesion |
IEA | -- |
SIGLEC12 for ontologies About GeneDecksing
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Drugs & Compounds
for SIGLEC12 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SIGLEC12 for compounds About GeneDecksing
 Browse Tocris compounds for SIGLEC12
3 Novoseek chemical compound relationships for SIGLEC12 gene About this table
Search CenterWatch for drugs/clinical trials and news about SIGLEC12 / SIG12
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Transcripts
for SIGLEC12 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SIGLEC12 gene (2 alternative transcripts): NM_033329.1 NM_053003.2 Unigene Cluster for SIGLEC12: Sialic acid binding Ig-like lectin 12 (gene/pseudogene) Hs.249741 [show with all ESTs]Unigene Representative Sequence: AY3581401 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000291707(uc002pww.1 uc002pwx.1 uc010eoy.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SIGLEC12 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SIGLEC12 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): SIGLEC12 (NM_053003) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SIGLEC12 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SIGLEC12 |
Additional cDNA sequence: AF282256.1 AK095919.1 AK225931.1 AY358140.1 BC035809.1 2 DOTS entries: DT.100016662 DT.99957558 9 AceView cDNA sequences: AK095919 NM_033329 NM_053003 BC035809 AF282256 AY358140 BP338210 AI132995 BM922492
GeneLoc Exon Structure
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Expression
for SIGLEC12 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SIGLEC12 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGTGCAACA
About this image
Genevestigator expression for SIGLEC12
SOURCE GeneReport for Unigene cluster: Hs.249741
UniProtKB/Swiss-Prot: SIG12_HUMAN, Q96PQ1Tissue specificity: Isoform Short is highly expressed in spleen, small intestine and adrenal gland; it is lowerexpressed in thyroid, placenta, brain, stomach, bone marrow, spinal chord and breast. Isoform Long is highly expressedin spleen, small intestine and bone marrow; it is lower expressed in thyroid, placenta, thymus, trachea, stomach,lung, adrenal gland, fetal brain and testis
SABiosciences Custom PCR Arrays for SIGLEC12
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SIGLEC12
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SIGLEC12 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SIGLEC12 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SIGLEC12 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIGLEC12 |
Orthologs
for SIGLEC12 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for SIGLEC12 gene from 2/4 species (see all 4) About this table
ENSEMBL Gene Tree for SIGLEC12 (if available)
TreeFam Gene Tree for SIGLEC12 (if available) |
Paralogs
for SIGLEC12 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SIGLEC12 gene
- CD332 SIGLEC17P2 SIGLEC82 SIGLEC52 SIGLEC162 SIGLEC112 SIGLEC62 SIGLEC142
- MAG2 SIGLEC102 SIGLEC72 SIGLEC92
9 SIMAP similar genes for SIGLEC12 using alignment to 2 protein entries: SIG12_HUMAN (see all proteins):SIGLEC7 SIGLEC9 SIGLEC6 SIGLEC8 SIGLEC14 SIGLEC16
SIGLEC10 CD33 SIGLEC5
SIGLEC12 for paralogs About GeneDecksing
5 Pseudogenes.org Pseudogenes for SIGLEC12
PGOHUM00000234737 PGOHUM00000234738 PGOHUM00000234741 PGOHUM00000234743 PGOHUM00000243760
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Genomic Variants
for SIGLEC12 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SIGLEC12 (51994613 - 52005043 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SIGLEC12
2 CNVs: 7214 4085
Human Gene Mutation Database (HGMD): SIGLEC12
| SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for SIGLEC12 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SIGLEC12 for disorders About GeneDecksing
OMIM gene information: 606094
OMIM disorders: --
6  diseases for SIGLEC12: About MalaCardshepatitis b prostate carcinoma hepatitis prostatitis
thyroiditis carcinoma
Human Genome Epidemiology (HuGE) Navigator: SIGLEC12 (4 documents)
Export disorders for SIGLEC12 gene to outside databases
|
Publications
for SIGLEC12 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SIGLEC12 gene, integrated from 9 sources (see all 31):
(articles sorted by number of sources associating them with SIGLEC12) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and molecular characterization of two splice variants of a new putative member of the Siglec-3-like subgroup of Siglecs. (PubMed id 11409877)1, 2, 3, 9 Foussias G....Diamandis E.P. (2001)
- SIGLEC12, a human-specific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomas. (PubMed id 21555517)1, 3 Mitra N....Varki A. (2011)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- A second uniquely human mutation affecting sialic acid biology. (PubMed id 11546777)1, 2 Angata T.... Varki A. (2001)
- Identification and characterization of S2V, a novel putative siglec that contains two V set Ig-like domains and recruits protein-tyrosine phosphatases SHPs. (PubMed id 11328818)1, 3 Yu Z....Shen S.H. (2001)
- New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
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External Searches for SIGLEC12 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SIGLEC12 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SIGLEC12 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SIGLEC12 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SIGLEC12 | Pharmacogenomics, SNPs, Pathways | | Functional Glycomics Gateway - Glycan Binding | http://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Itlect_276 |
|
| | |
About This Section
| Patent Information for SIGLEC12 gene:
Search GeneIP for patents involving SIGLEC12
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SIGLEC12 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SIGLEC12 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SIGLEC12 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SIGLEC12 | | | OriGene Protein Over-expression Lysate for SIGLEC12 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SIGLEC12 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SIGLEC12 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SIGLEC12 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SIGLEC12 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SIGLEC12 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SIGLEC12 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SIGLEC12 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SIGLEC12 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SIGLEC12 |
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 | | | SIGLEC12 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIGLEC12 |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SIGLEC12 |
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