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SIAE Gene

protein-coding   GIFtS: 50
GCID: GC11M124505

Sialic Acid Acetylesterase

(Previous name: Ysg2 homolog (mouse))
(Previous symbol: YSG2)
  See SIAE-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Sialic Acid Acetylesterase1 2     CSE-C2
YSG21 2 3     CSEC2
Sialic Acid-Specific Acetylesterase II1 2     LSE2
H-Lse2 3     Cytosolic Sialic Acid 9-O-Acetylesterase Homolog2
EC 3.1.1.533 8     Sialate O-Acetylesterase2
AIS62 5     Sialic Acid-Specific 9-O-Acetylesterase3
Ysg2 Homolog (Mouse)1     

External Ids:    HGNC: 181871   Entrez Gene: 544142   Ensembl: ENSG000001100137   OMIM: 6100795   UniProtKB: Q9HAT23   

Export aliases for SIAE gene to outside databases

Previous GC identifers: GC11M124011 GC11M120448


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SIAE Gene:
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene
are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different
isoforms, found either in the cytosol or in the lysosome, have been found for this gene.(provided by RefSeq, Feb
2011)

GeneCards Summary for SIAE Gene:
SIAE (sialic acid acetylesterase) is a protein-coding gene. Diseases associated with SIAE include autoimmune disease 6. GO annotations related to this gene include and sialate O-acetylesterase activity.

UniProtKB/Swiss-Prot: SIAE_HUMAN, Q9HAT2
Function: Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid,
N-acetylneuraminic acid




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_033899.9  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SIAE gene promoter:
         TBP   PPAR-gamma1   NF-1   AML1a   COMP1   Lmo2   PPAR-gamma2   IRF-1   HNF-4alpha2   HNF-4alpha1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSIAE promoter sequence
   Search Chromatin IP Primers for SIAE

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SIAE


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q24   Ensembl cytogenetic band:  11q24.2   HGNC cytogenetic band: 11q24

SIAE Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SIAE gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M124505:  view genomic region     (about GC identifiers)

Start:
124,503,009 bp from pter      End:
124,565,603 bp from pter
Size:
62,595 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: SIAE_HUMAN, Q9HAT2 (See protein sequence)
Recommended Name: Sialate O-acetylesterase precursor  
Size: 523 amino acids; 58315 Da
Secondary accessions: B3KPB0 Q8IUT9 Q9HAU7 Q9NT71
Alternative splicing: 2 isoforms:  Q9HAT2-1   Q9HAT2-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SIAE: NX_Q9HAT2

Explore proteomics data for SIAE at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn107, Asn138, Asn267, Asn290, Asn401, Asn422
  • Modification sites at PhosphoSitePlus
  • 3 DME Specific Peptides for SIAE (Q9HAT2)
     LQYPIGL  HSVLWNAMI  LKGVVWYQGE 


    See SIAE Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001186851.1  NP_733746.1  

    ENSEMBL proteins: 
     ENSP00000263593   ENSP00000437877  

    SIAE Human Recombinant Protein Products:

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    Novus Biologicals SIAE Protein
    Novus Biologicals SIAE Lysates
    Sino Biological Recombinant Protein for SIAE
    Sino Biological Cell Lysate for SIAE
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SIAE

     
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    antibodies-online proteins for SIAE (6 products) 

     
    Search antibodies-online for peptides for SIAE

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    antibodies-online antibodies for SIAE (2 products) 

    SIAE Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for SIAE
    Cloud-Clone Corp. CLIAs for SIAE
    Search eBioscience for ELISAs for SIAE 
    antibodies-online kits for SIAE (13 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR005181 DUF303_acetylest

    Graphical View of Domain Structure for InterPro Entry Q9HAT2

    ProtoNet protein and cluster: Q9HAT2


    Find genes that share domains with SIAE           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SIAE_HUMAN, Q9HAT2
    Function: Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid,
    N-acetylneuraminic acid
    Catalytic activity: N-acetyl-O-acetylneuraminate + H(2)O = N-acetylneuraminate + acetate

         Enzyme Number (IUBMB): EC 3.1.1.531 2

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001681sialate O-acetylesterase activity IDA--
         
    Find genes that share ontologies with SIAE           About GenesLikeMe


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Siae):
     hematopoietic system  immune system  no phenotypic analysis  renal/urinary system 

    Find genes that share phenotypes with SIAE           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Siaetm1.2Avrk for SIAE

       genOway: Develop your customized and physiologically relevant rodent model for SIAE

    miRNA
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    Block miRNA regulation of human, mouse, rat SIAE using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate SIAE:
    hsa-miR-1276 hsa-miR-3688-3p hsa-miR-1252 hsa-miR-3133
    SwitchGear 3'UTR luciferase reporter plasmidSIAE 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SIAE

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    Sino Biological Human cDNA Clone for SIAE
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SIAE

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIAE


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SIAE_HUMAN, Q9HAT2: Lysosome (Probable). Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    lysosome4
    vacuole4
    cytosol2
    endoplasmic reticulum2
    nucleus2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005764lysosome IEA--
    GO:0070062extracellular vesicular exosome IDA19056867

    Find genes that share ontologies with SIAE           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SIAE
    Interactions:

        Search GeneGlobe Interaction Network for SIAE

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002682regulation of immune system process IMP--
    GO:0005975carbohydrate metabolic process IDA--

    Find genes that share ontologies with SIAE           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SIAE

    3 HMDB Compounds for SIAE    About this table
    CompoundSynonyms CAS #PubMed Ids
    Acetic acidAcetate (see all 12)64-19-7--
    N-Acetylneuraminic acidSialic acid (see all 55)131-48-6--
    WaterDihydrogen oxide (see all 2)7732-18-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SIAE gene (3 alternative transcripts): 
    NM_001199922.1  NM_170601.4  NM_018978.1  

    Unigene Cluster for SIAE:

    Sialic acid acetylesterase
    Hs.10056  [show with all ESTs]
    Unigene Representative Sequence: NM_001199922
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263593(uc001qan.3 uc021qru.1) ENST00000533613 ENST00000436137(uc001qao.2)
    ENST00000525730 ENST00000545756
    miRNA
    Products:
         
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    4 qRT-PCR Assays for microRNAs that regulate SIAE:
    hsa-miR-1276 hsa-miR-3688-3p hsa-miR-1252 hsa-miR-3133
    SwitchGear 3'UTR luciferase reporter plasmidSIAE 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SIAE
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SIAE
      QuantiTect SYBR Green Assays in human, mouse, rat SIAE
      QuantiFast Probe-based Assays in human, mouse, rat SIAE

    Additional mRNA sequence: 

    AF300796.1 AF303378.1 AK056093.1 AK092224.1 AL137496.1 BC022456.1 BC068450.1 

    5 DOTS entries:

    DT.95265897  DT.95260668  DT.95363553  DT.97765290  DT.40122733 

    Selected AceView cDNA sequences (see all 161):

    BU618578 BQ010054 AA987944 CA420039 W42869 AA403039 R10303 AI400642 
    BM710185 AA252893 AI040845 AA772356 AA639769 AA694474 BX507522 AA910676 
    AF303378 AK056093 AI056195 BQ019261 T49454 AA782685 NM_170601 AA213991 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SIAE expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACAAGCATAT
    SIAE Expression
    About this image


    SIAE expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Midbrain tegmentum
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Neural Tube (Nervous System)
             Metencephalon
     
     Thyroid (Endocrine System)
     
     Colon (Gastrointestinal Tract)
    SIAE Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SIAE Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.10056

    UniProtKB/Swiss-Prot: SIAE_HUMAN, Q9HAT2
    Tissue specificity: Widely expressed with high expression in the testis, prostate, and colon

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SIAE

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SIAE gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Siae1 , 5 sialic acid acetylesterase1, 5 82.73(n)1
    80.8(a)1
      9 (20.79 cM)5
    226191  NM_011734.31  NP_035864.21 
     376138475 
    lizard
    (Anolis carolinensis)
    Reptilia SIAE6
    sialic acid acetylesterase
    52(a)
    1 ↔ 1
    GL343322.1(160228-176684)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC686882 hypothetical protein MGC68688 73.05(n)    BC059983.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc564542 similar to yolk sac gene 2 76.4(n)   393259  BC049448.1 


    ENSEMBL Gene Tree for SIAE (if available)
    TreeFam Gene Tree for SIAE (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SIAE (see all 863)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1430705991,2,,4
    C,FAutoimmune disease 6 (AIS6)4 other1124386186(+) GCCAGC/AACACT 4 /C /F mis11Minor allele frequency- A:0.00NA 4552
    VAR_0644454
    Autoimmune disease 6 (AIS6)4--see VAR_0644452 G R mis40--------
    VAR_0644544
    Autoimmune disease 6 (AIS6)4--see VAR_0644542 F S mis40--------
    VAR_0644484
    Autoimmune disease 6 (AIS6)4--see VAR_0644482 Q P mis40--------
    VAR_0644514
    Autoimmune disease 6 (AIS6)4--see VAR_0644512 Y C mis40--------
    VAR_0644524
    Autoimmune disease 6 (AIS6)4--see VAR_0644522 R H mis40--------
    VAR_0644474
    Autoimmune disease 6 (AIS6)4--see VAR_0644472 C G mis40--------
    VAR_0644464
    Autoimmune disease 6 (AIS6)4--see VAR_0644462 R W mis40--------
    VAR_0644584
    Autoimmune disease 6 (AIS6)4--see VAR_0644582 R C mis40--------
    rs2018771491,2
    C,Fother1124375082(+) CTTCAA/GAGGTC 4 S F mis11Minor allele frequency- G:0.00EU 1323

    HapMap Linkage Disequilibrium report for SIAE (124503009 - 124565603 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SIAE:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2678188CNV Deletion23128226

    Human Gene Mutation Database (HGMD): SIAE
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SIAE
    DNA2.0 Custom Variant and Variant Library Synthesis for SIAE

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610079   
    OMIM disorders: 613551  
    UniProtKB/Swiss-Prot: SIAE_HUMAN, Q9HAT2
  • Autoimmune disease 6 (AIS6) [MIM:613551]: Individuals manifesting susceptibility to autoimmune disease
    type 6 can suffer from juvenile idiopathic arthritis, rheumatoid arthritis, multiple sclerosis, Sjogren syndrome,
    systemic lupus erythematosus, type 1 diabetes, ulcerative colitis, and Crohn disease. Note=Disease susceptibility
    is associated with variations affecting the gene represented in this entry

  • 1 disease for SIAE:    
    About MalaCards
    autoimmune disease 6


    Find genes that share disorders with SIAE           About GenesLikeMe

    Genetic Association Database (GAD): SIAE
    Human Genome Epidemiology (HuGE) Navigator: SIAE (4 documents)

    Export disorders for SIAE gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SIAE gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with SIAE)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Functionally defective germline variants of sialic acid acetylesterase in autoimmunity. (PubMed id 20555325)1, 2, 4 Surolia I.... Pillai S. (Nature 2010)
    2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    3. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. (PubMed id 18711365)1, 4 Ferreira M.A....Craddock N. (Nat. Genet. 2008)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. A gene encoding sialic-acid-specific 9-O-acetylesterase found in human adult testis. (PubMed id 15292578)1, 2 Zhu H....Sha J.H. (J. Biomed. Biotechnol. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. Lysosomal and cytosolic sialic acid 9-O-acetylesterase activities can Be encoded by one gene via differential usage of a signal peptide-encoding exon at the N terminus. (PubMed id 10464298)1, 3 Takematsu H....Varki A. (J. Biol. Chem. 1999)
    8. M89V Sialic acid Acetyl Esterase (SIAE) and all other non-synonymous common variants of this gene are catalytically normal. (PubMed id 23308225)1 Chellappa V....Pillai S. (PLoS ONE 2013)
    9. No evidence for rare pathological SIAE coding variants in patients with vitiligo. (PubMed id 22913750)1 Al-Yami N....Alkuraya F.S. (Int. J. Dermatol. 2013)
    10. Regulation of O-acetylation of sialic acids by sialate-O-acetyltransferase and sialate-O-acetylesterase activities in childhood acute lymphoblastic leukemia. (PubMed id 21803834)1 Mandal C....Mandal C. (Glycobiology 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54414 HGNC: 18187 AceView: CSE-C Ensembl:ENSG00000110013 euGenes: HUgn54414
    ECgene: SIAE H-InvDB: SIAE

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SIAE Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SIAE gene:
    Search GeneIP for patents involving SIAE

    GeneCards and IP:
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