Aliases for SIAE Gene
External Ids for SIAE Gene
Previous HGNC Symbols for SIAE Gene
Previous GeneCards Identifiers for SIAE Gene
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011]
GeneCards Summary for SIAE Gene
SIAE (Sialic Acid Acetylesterase) is a Protein Coding gene. Diseases associated with SIAE include Autoimmune Disease 6 and Marasmus. GO annotations related to this gene include sialate O-acetylesterase activity.
UniProtKB/Swiss-Prot for SIAE Gene
Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid.