Aliases for SHROOM2 Gene
External Ids for SHROOM2 Gene
Previous HGNC Symbols for SHROOM2 Gene
Previous GeneCards Identifiers for SHROOM2 Gene
The protein encoded by this gene shares significant similarities with the apical protein from Xenopus laevis which is implicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinism type 1 syndrome. [provided by RefSeq, Jul 2008]
GeneCards Summary for SHROOM2 Gene
SHROOM2 (Shroom Family Member 2) is a Protein Coding gene. Diseases associated with SHROOM2 include ocular albinism. Among its related pathways are Tight junction. GO annotations related to this gene include actin binding and actin filament binding. An important paralog of this gene is SHROOM1.
UniProtKB/Swiss-Prot for SHROOM2 Gene
May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity).