Aliases for SHPK Gene
External Ids for SHPK Gene
Previous Symbols for SHPK Gene
The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq, Jul 2008]
GeneCards Summary for SHPK Gene
SHPK (Sedoheptulokinase) is a Protein Coding gene. GO annotations related to this gene include sedoheptulokinase activity.
UniProtKB/Swiss-Prot for SHPK Gene
Acts as a modulator of macrophage activation through control of glucose metabolism.