External Ids for SHKBP1 Gene
Previous GeneCards Identifiers for SHKBP1 Gene
GeneCards Summary for SHKBP1 Gene
SHKBP1 (SH3KBP1 Binding Protein 1) is a Protein Coding gene. An important paralog of this gene is KCTD5.
UniProtKB/Swiss-Prot for SHKBP1 Gene
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.