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Aliases for SHISA7 Gene

Aliases for SHISA7 Gene

  • Shisa Family Member 7 2 3 5
  • Shisa Homolog 7 (Xenopus Laevis) 2
  • Protein Shisa-6-Like 4

External Ids for SHISA7 Gene

Previous GeneCards Identifiers for SHISA7 Gene

  • GC19M060639
  • GC19M055940
  • GC19M052263

Summaries for SHISA7 Gene

GeneCards Summary for SHISA7 Gene

SHISA7 (Shisa Family Member 7) is a Protein Coding gene. An important paralog of this gene is SHISA8.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SHISA7 Gene

Genomics for SHISA7 Gene

Regulatory Elements for SHISA7 Gene

Promoters for SHISA7 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SHISA7 on UCSC Golden Path with GeneCards custom track

Genomic Location for SHISA7 Gene

55,428,738 bp from pter
55,442,863 bp from pter
14,126 bases
Minus strand

Genomic View for SHISA7 Gene

Genes around SHISA7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SHISA7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SHISA7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SHISA7 Gene

Proteins for SHISA7 Gene

  • Protein details for SHISA7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein shisa-7
    Protein Accession:

    Protein attributes for SHISA7 Gene

    538 amino acids
    Molecular mass:
    56214 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SHISA7 Gene

Proteomics data for SHISA7 Gene at MOPED

Post-translational modifications for SHISA7 Gene

  • Glycosylation at Asn 23 and Asn 59
  • Modification sites at PhosphoSitePlus

Other Protein References for SHISA7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SHISA7 Gene

Domains & Families for SHISA7 Gene

Gene Families for SHISA7 Gene

Protein Domains for SHISA7 Gene


Suggested Antigen Peptide Sequences for SHISA7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the shisa family.
  • Belongs to the shisa family.
genes like me logo Genes that share domains with SHISA7: view

Function for SHISA7 Gene

Phenotypes for SHISA7 Gene

GenomeRNAi human phenotypes for SHISA7:
genes like me logo Genes that share phenotypes with SHISA7: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SHISA7 Gene

Localization for SHISA7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SHISA7 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SHISA7 Gene COMPARTMENTS Subcellular localization image for SHISA7 gene
Compartment Confidence
plasma membrane 4
extracellular 2
golgi apparatus 1
lysosome 1
mitochondrion 1
vacuole 1

Gene Ontology (GO) - Cellular Components for SHISA7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045202 synapse IBA --
genes like me logo Genes that share ontologies with SHISA7: view

Pathways & Interactions for SHISA7 Gene

SuperPathways for SHISA7 Gene

No Data Available

Interacting Proteins for SHISA7 Gene

Gene Ontology (GO) - Biological Process for SHISA7 Gene


No data available for Pathways by source and SIGNOR curated interactions for SHISA7 Gene

Drugs & Compounds for SHISA7 Gene

No Compound Related Data Available

Transcripts for SHISA7 Gene

mRNA/cDNA for SHISA7 Gene

(2) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SHISA7 Gene

Shisa homolog 7 (Xenopus laevis):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SHISA7 Gene

No ASD Table

Relevant External Links for SHISA7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SHISA7 Gene

mRNA expression in normal human tissues for SHISA7 Gene

mRNA differential expression in normal tissues according to GTEx for SHISA7 Gene

This gene is overexpressed in Brain - Nucleus accumbens (basal ganglia) (x6.5), Brain - Cortex (x5.8), Brain - Putamen (basal ganglia) (x5.0), Brain - Caudate (basal ganglia) (x4.8), Brain - Hippocampus (x4.7), Brain - Anterior cingulate cortex (BA24) (x4.4), Brain - Amygdala (x4.2), and Brain - Frontal Cortex (BA9) (x4.1).

Protein differential expression in normal tissues from HIPED for SHISA7 Gene

This gene is overexpressed in Frontal cortex (61.6) and Fetal Liver (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SHISA7 Gene

SOURCE GeneReport for Unigene cluster for SHISA7 Gene Hs.6664

genes like me logo Genes that share expression patterns with SHISA7: view

Protein tissue co-expression partners for SHISA7 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SHISA7 Gene

Orthologs for SHISA7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SHISA7 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SHISA7 35
  • 91.35 (n)
  • 94.13 (a)
  • 82 (a)
(Canis familiaris)
Mammalia SHISA7 36
  • 74 (a)
  • 90.11 (n)
  • 93.21 (a)
(Mus musculus)
Mammalia Shisa7 16
Shisa7 36
  • 88 (a)
Shisa7 35
  • 87.44 (n)
  • 93.5 (a)
(Ornithorhynchus anatinus)
Mammalia SHISA7 36
  • 55 (a)
(Rattus norvegicus)
Mammalia Shisa7 35
  • 87.06 (n)
  • 93.69 (a)
(Anolis carolinensis)
Reptilia SHISA7 36
  • 43 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia shisa7 35
  • 58.91 (n)
  • 57.6 (a)
(Danio rerio)
Actinopterygii LOC101883130 35
  • 56.22 (n)
  • 52.61 (a)
shisa7 36
  • 27 (a)
SHISA7 (1 of 2) 36
  • 33 (a)
Species with no ortholog for SHISA7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SHISA7 Gene

Gene Tree for SHISA7 (if available)
Gene Tree for SHISA7 (if available)

Paralogs for SHISA7 Gene

Paralogs for SHISA7 Gene

genes like me logo Genes that share paralogs with SHISA7: view

Variants for SHISA7 Gene

Sequence variations from dbSNP and Humsavar for SHISA7 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs4801280 -- 55,436,499(+) tcagg(A/G)ggcta intron-variant
rs34537062 -- 55,444,348(+) TTACA(-/A)AAAAA upstream-variant-2KB
rs35642573 -- 55,439,863(+) TACCT(-/C)CCCCT intron-variant
rs35651822 -- 55,435,954(+) TACAC(-/ATGT)GTGTG intron-variant
rs28612745 -- 55,431,183(+) AAGTG(C/G)ATCCC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for SHISA7 Gene

Variant ID Type Subtype PubMed ID
nsv912457 CNV Loss 21882294
nsv912463 CNV Loss 21882294
nsv912473 CNV Loss 21882294
dgv4021n71 CNV Loss 21882294
nsv912478 CNV Loss 21882294
dgv600n67 CNV Loss 20364138

Variation tolerance for SHISA7 Gene

Gene Damage Index Score: 0.64; 13.72% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SHISA7 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SHISA7 Gene

Disorders for SHISA7 Gene

Relevant External Links for SHISA7

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SHISA7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SHISA7 Gene

Publications for SHISA7 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3

Products for SHISA7 Gene

Sources for SHISA7 Gene

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