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Aliases for SHISA7 Gene

Aliases for SHISA7 Gene

  • Shisa Family Member 7 2 3
  • Shisa Homolog 7 (Xenopus Laevis) 2
  • Protein Shisa-6-Like 4

External Ids for SHISA7 Gene

Summaries for SHISA7 Gene

GeneCards Summary for SHISA7 Gene

SHISA7 (Shisa Family Member 7) is a Protein Coding gene. An important paralog of this gene is SHISA8.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SHISA7 Gene

Genomics for SHISA7 Gene

Genomic Location for SHISA7 Gene

Start:
55,428,738 bp from pter
End:
55,442,863 bp from pter
Size:
14,126 bases
Orientation:
Minus strand

Genomic View for SHISA7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SHISA7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SHISA7 Gene

No data available for Regulatory Elements for SHISA7 Gene

Proteins for SHISA7 Gene

  • Protein details for SHISA7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NL88-SHSA7_HUMAN
    Recommended name:
    Protein shisa-7
    Protein Accession:
    A6NL88
    Secondary Accessions:

    Protein attributes for SHISA7 Gene

    Size:
    538 amino acids
    Molecular mass:
    56214 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SHISA7 Gene

Proteomics data for SHISA7 Gene at MOPED

Post-translational modifications for SHISA7 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn23 and Asn59

Other Protein References for SHISA7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SHISA7 Gene

Domains for SHISA7 Gene

Gene Families for SHISA7 Gene

HGNC:

Protein Domains for SHISA7 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

SHSA7_HUMAN
Family:
  • Belongs to the shisa family.:
    • A6NL88
genes like me logo Genes that share domains with SHISA7: view

Function for SHISA7 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SHISA7 Gene

Localization for SHISA7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SHISA7 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SHISA7 Gene COMPARTMENTS Subcellular localization image for SHISA7 gene
Compartment Confidence
extracellular 2
plasma membrane 2
golgi apparatus 1
lysosome 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for SHISA7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SHISA7: view

Pathways for SHISA7 Gene

SuperPathways for SHISA7 Gene

No Data Available

Interacting Proteins for SHISA7 Gene

Gene Ontology (GO) - Biological Process for SHISA7 Gene

None

No data available for Pathways by source for SHISA7 Gene

Transcripts for SHISA7 Gene

mRNA/cDNA for SHISA7 Gene

(2) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SHISA7 Gene

Shisa homolog 7 (Xenopus laevis):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SHISA7 Gene

No ASD Table

Relevant External Links for SHISA7 Gene

GeneLoc Exon Structure for
SHISA7
ECgene alternative splicing isoforms for
SHISA7

Expression for SHISA7 Gene

mRNA expression in normal human tissues for SHISA7 Gene

mRNA differential expression in normal tissues according to GTEx for SHISA7 Gene

This gene is overexpressed in Brain - Nucleus accumbens (basal ganglia) (6.5), Brain - Cortex (5.8), Brain - Putamen (basal ganglia) (5.0), Brain - Caudate (basal ganglia) (4.8), Brain - Hippocampus (4.7), Brain - Anterior cingulate cortex (BA24) (4.4), Brain - Amygdala (4.2), and Brain - Frontal Cortex (BA9) (4.1).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for SHISA7 Gene

SOURCE GeneReport for Unigene cluster for SHISA7 Gene Hs.6664

genes like me logo Genes that share expressions with SHISA7: view

Orthologs for SHISA7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SHISA7 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SHISA7 36
  • 91.35 (n)
  • 94.13 (a)
SHISA7 37
  • 82 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SHISA7 36
  • 90.11 (n)
  • 93.21 (a)
SHISA7 37
  • 74 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Shisa7 36
  • 87.44 (n)
  • 93.5 (a)
Shisa7 16
Shisa7 37
  • 88 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SHISA7 37
  • 55 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Shisa7 36
  • 87.06 (n)
  • 93.69 (a)
lizard
(Anolis carolinensis)
Reptilia SHISA7 37
  • 43 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia shisa7 36
  • 58.91 (n)
  • 57.6 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC101883130 36
  • 56.22 (n)
  • 52.61 (a)
shisa7 37
  • 27 (a)
OneToMany
SHISA7 (1 of 2) 37
  • 33 (a)
OneToMany
Species with no ortholog for SHISA7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SHISA7 Gene

ENSEMBL:
Gene Tree for SHISA7 (if available)
TreeFam:
Gene Tree for SHISA7 (if available)

Paralogs for SHISA7 Gene

Paralogs for SHISA7 Gene

genes like me logo Genes that share paralogs with SHISA7: view

Variants for SHISA7 Gene

Sequence variations from dbSNP and Humsavar for SHISA7 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs4075908 -- 55,430,460(+) TGGTT(A/G)CAGTG utr-variant-3-prime
rs4133107 -- 55,443,096(+) ACGCG(C/T)GGTGG upstream-variant-2KB
rs4801280 -- 55,436,499(+) tcagg(A/G)ggcta intron-variant
rs4801603 -- 55,429,931(+) TGACC(C/T)ATCCC utr-variant-3-prime
rs4801608 -- 55,430,141(+) TCAGG(A/G)GGGGC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for SHISA7 Gene

Variant ID Type Subtype PubMed ID
nsv912457 CNV Loss 21882294
nsv912463 CNV Loss 21882294
nsv912473 CNV Loss 21882294
dgv4021n71 CNV Loss 21882294
nsv912478 CNV Loss 21882294
dgv600n67 CNV Loss 20364138

Relevant External Links for SHISA7 Gene

HapMap Linkage Disequilibrium report
SHISA7

Disorders for SHISA7 Gene

No disorders were found for SHISA7 Gene.

No data available for UniProtKB/Swiss-Prot for SHISA7 Gene

Publications for SHISA7 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  2. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for SHISA7 Gene

Sources for SHISA7 Gene

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