Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SHISA6 Gene

protein-coding GIFtS: 43
GCID: GC17P011144

shisa homolog 6 (Xenopus laevis)

Search for SHISA6
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Shisa Homolog 6 (Xenopus Laevis)¹ ²
FLJ45455¹
Protein Shisa-6 Homolog²

External Ids:	HGNC: 34491¹	Entrez Gene: 388336²	Ensembl: ENSG00000188803⁷	UniProtKB: Q6ZSJ9³

Export aliases for SHISA6 gene to outside databases

Previous GC identifers: GC17P011086 GC17P011046

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000017.10 NC_018928.1 NT_010718.16

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for SHISA6
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for SHISA6

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SHISA6

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p12 Ensembl cytogenetic band: 17p12 HGNC cytogenetic band: 17p13.1-p12

SHISA6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SHISA6 gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17P011144: view genomic region (about GC identifiers)

Start:	11,144,580 bp from pter	End:	11,467,380 bp from pter
Size:	322,801 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SHSA6_HUMAN, Q6ZSJ9 (See protein sequence)

Recommended Name: Protein shisa-6 homolog precursor

Size: 500 amino acids; 55764 Da

Subcellular location: Membrane; Single-pass type I membrane protein (Potential)

Sequence caution: Sequence=BAC86949.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Sequence=BAG54617.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Secondary accessions: B3KXV5 Q4PL63

Alternative splicing: 3 isoforms: Q6ZSJ9-1 Q6ZSJ9-2 Q6ZSJ9-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SHISA6: NX_Q6ZSJ9

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6ZSJ9

SHISA6 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001166932.1 NP_001166933.1 NP_997269.2

ENSEMBL proteins:

ENSP00000390084 ENSP00000388659 ENSP00000387157

Human Recombinant Protein Products for SHISA6:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for SHISA6
	GenScript Custom Purified and Recombinant Proteins Services for SHISA6
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for SHISA6

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016021	integral to membrane	IEA	--

SHISA6 for ontologies About GeneDecksing

SHISA6 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for SHISA6
	GenScript Custom Superior Antibodies Services for SHISA6
	Novus Biologicals SHISA6 Antibody
	Abcam antibodies for SHISA6
	Uscn Antibodies for SHISA6
	Search ThermoFisher Antibodies for SHISA6

Assay Products for SHISA6:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for SHISA6
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for SHISA6

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SHISA6 for domains About GeneDecksing

1 InterPro domain/family:

IPR026910 Shisa

Graphical View of Domain Structure for InterPro Entry Q6ZSJ9

ProtoNet protein and cluster: Q6ZSJ9

UniProtKB/Swiss-Prot: SHSA6_HUMAN, Q6ZSJ9

Similarity: Belongs to the shisa family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Phenotypes:
1 GenomeRNAi human phenotype for SHISA6:

Decreased viability with cispl

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SHISA6

miRNA Products:		OriGene 3'-UTR Clone: SHISA6 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SHISA6
		8/103 QIAGEN miScript miRNA Assays for microRNAs that regulate SHISA6 (see all 103):
		hsa-miR-194* hsa-miR-4254 hsa-miR-128 hsa-miR-374a hsa-miR-3916 hsa-miR-4267 hsa-miR-890 hsa-miR-208b

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SHISA6 (see all 4) OriGene shRNA RFP: SHISA6 OriGene siRNA: SHISA6
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SHISA6
		Sirion Biotech Custom design and validation of potent shRNA sequences against SHISA6

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for SHISA6
			Sirion Biotech Customized adenovirus for overexpression of SHISA6 Sirion Biotech Customized adenovirus for potent knockdown of SHISA6

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SHISA6 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SHISA6 (see all 4) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 3): SHISA6 (NM_207386)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SHISA6
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SHISA6

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for SHISA6
		Search LifeMap BioReagents cell lines for SHISA6
		Sirion Biotech Customized stable knockdown cell line services for SHISA6 Sirion Biotech Customized inducible knockdown cell line services for SHISA6 Sirion Biotech Customized stable overexpressing cell line services for SHISA6 Sirion Biotech Customized inducible overexpressing cell line services for SHISA6

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SHISA6

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SHISA6

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SHISA6
Search CenterWatch for drugs/clinical trials and news about SHISA6 / SHSA6

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SHISA6 gene (4 alternative transcripts):

NM_175903.2 NM_001173461.1 NM_001173462.1 NM_207386.3

Unigene Cluster for SHISA6:

Shisa homolog 6 (Xenopus laevis)

Hs.592124 [show with all ESTs]

Unigene Representative Sequence: NM_207386

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000441885(uc002gnc.2) ENST00000432116(uc010com.3) ENST00000409168(uc002gna.4 uc010con.3)

ENST00000343478

miRNA Products:		OriGene 3'-UTR Clone: SHISA6 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SHISA6
		8/103 QIAGEN miScript miRNA Assays for microRNAs that regulate SHISA6 (see all 103):
		hsa-miR-194* hsa-miR-4254 hsa-miR-128 hsa-miR-374a hsa-miR-3916 hsa-miR-4267 hsa-miR-890 hsa-miR-208b

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SHISA6 (see all 4) OriGene shRNA RFP: SHISA6 OriGene siRNA: SHISA6
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SHISA6
		Sirion Biotech Custom design and validation of potent shRNA sequences against SHISA6

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SHISA6 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SHISA6 (see all 4) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 3): SHISA6 (NM_207386)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SHISA6
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SHISA6

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SHISA6 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat SHISA6
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SHISA6
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SHISA6

Additional cDNA sequence:

AK094349.1 AK095052.1 AK127379.1 AK128003.1 BC105704.1 BC105705.1 BC105706.1 BC105707.1

DQ070854.1

6 DOTS entries:

DT.92043545 DT.101976590 DT.101976589 DT.441340 DT.120996616 DT.40289368

10 AceView cDNA sequences:

NM_207386 AA441990 AK127379 AK128003 AA460977 AI370640 BX109938 AI126777

R46311 AA461286

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for SHISA6 About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5a	·	5b
SP1:
SP2:							-
SP3:					-		-

ECgene alternative splicing isoforms for SHISA6

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SHISA6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TACTGTAAAC

About this image

SHISA6 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Inner Nuclear Layer

nGnG Amacrine Cells

Amacrine, Retina

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

See SHISA6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SHISA6

SOURCE GeneReport for Unigene cluster: Hs.592124

UniProtKB/Swiss-Prot: SHSA6_HUMAN, Q6ZSJ9

Tissue specificity: Expressed in the developing ventral mesencephalon

SABiosciences Custom PCR Arrays for SHISA6

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SHISA6 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat SHISA6
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SHISA6
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SHISA6

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SHISA6

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for SHISA6 gene from 3/9 species (see all 9) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	SHISA6¹	shisa homolog 6 (Xenopus laevis)	77.88(n) 78.65(a)		768703 XM_001231790.2 XP_001231791.2
lizard (Anolis carolinensis)	Reptilia	-- --	--	82(a) 50(a)	1 ↔ many 1 ↔ many	2(104100647-104104403) 2(104475197-104495089)
zebrafish (Danio rerio)	Actinopterygii	LOC100332354¹	protein shisa-6 homolog	67.5(n) 68(a)		100332354 XM_002667291.1 XP_002667337.1

ENSEMBL Gene Tree for SHISA6 (if available)
TreeFam Gene Tree for SHISA6 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SHISA6 gene

SHISA8² SHISA7² SHISA9²

2 SIMAP similar genes for SHISA6 using alignment to 1 protein entry: SHSA6_HUMAN:

SHISA9 SHISA7

SHISA6 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs73291798^1,2	C	--	11143032(+)	`GCCTCG/ATAGCT`	3	--	us2k¹		2		WA	120
rs189223642^1,2		--	11143423(+)	`TTTGAC/TCTCTT`	3	--	us2k¹		0	--	--	--	--
rs6503362^1,2	C,F,A,H	--	11143493(+)	`CGCTCT/AGGCAG`	3	--	us2k¹		16		NS EA NA WA CSA	791
rs140325809^1,2		--	11143506(+)	`CGCTGC/TCCCGG`	3	--	us2k¹		0	--	--	--	--
rs145564544^1,2		--	11143617(+)	`GCTCCC/GGGCCC`	3	--	us2k¹		0	--	--	--	--
rs73291800^1,2	C	--	11143670(+)	`CGGAGC/TTTTCG`	3	--	us2k¹		2		WA	120
rs145396002^1,2	C	--	11143787(+)	`GCCCT-/CCCCTC CCCTGTCCCCCCT`	3	--	us2k¹		0	--	--	--	--
rs112412705^1,2	C	--	11144045(+)	`GCTCGT/CCGCCG`	3	--	us2k¹		2		NA	122
rs192776565^1,2		--	11144307(+)	`CTCCCA/GGAGCG`	3	--	us2k¹		0	--	--	--	--
rs138088998^1,2		--	11144826(+)	`GGCCGC/GGCCGC`	6	R	syn¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SHISA6 (11144580 - 11394580 bp, first 250kb of SHISA6)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for SHISA6
4 CNVs: 67136 35427 0494 7141
3 Indels: 67137 72792 72793

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SHISA6

DNA2.0 Custom Variant and Variant Library Synthesis for SHISA6

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SHISA6 for disorders About MalaCards

SHISA6 for disorders About GeneDecksing

Human Genome Epidemiology (HuGE) Navigator: SHISA6 (1 document)

Export disorders for SHISA6 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SHISA6 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SHISA6)

Utopia: connect your pdf to the dynamic
world of online information

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)² Zody M.C.... Nusbaum C. (2006)
Identification of novel genes regulated in the developing human ventral mesencephalon. (PubMed id 16473350)² Jorgensen J.R....Wahlberg L.U. (2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 388336	HGNC: 34491	AceView: FLJ45455	Ensembl:ENSG00000188803	euGenes: HUgn388336
ECgene: SHISA6	H-InvDB: SHISA6

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SHISA6	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SHISA6 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for SHISA6 gene:
Search GeneIP for patents involving SHISA6

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for SHISA6
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SHISA6		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SHISA6
	Browse OriGene Protein Over-expression Lysates		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for SHISA6		OriGene 3'-UTR Clone for SHISA6
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SHISA6		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SHISA6
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for SHISA6		OriGene Custom Protein Services for SHISA6
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SHISA6
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SHISA6
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SHISA6
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SHISA6
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SHISA6
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SHISA6

	GenScript Custom Purified and Recombinant Proteins Services for SHISA6		GenScript cDNA clones with any tag delivered in your preferred vector for SHISA6
	GenScript Custom Assay Services for SHISA6		GenScript Custom Superior Antibodies Services for SHISA6
	GenScript Custom overexpressing Cell Line Services for SHISA6		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Search Regulatory tfbs for SHISA6
	Search Chromatin IP Primers for SHISA6
	RT² qPCR Primer Assay in human, mouse, rat SHISA6
	Search GNC Networks for SHISA6
	SABiosciences Custom PCR Arrays for SHISA6

Search Tocris compounds for SHISA6

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	SHISA6 antibodies

	Antibodies for SHISA6
	See all of Abcam's Antibodies, Kits and Proteins for SHISA6
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

SHISA6 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for SHISA6

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SHISA6

	Browse SwitchGear 3'UTR luciferase reporter plasmids for SHISA6
	Browse SwitchGear Promoter luciferase reporter plasmids for SHISA6

Search ThermoFisher Antibodies for SHISA6

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SHISA6

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SHISA6

Sirion Biotech Customized:

	stable knockdown cell line services for SHISA6
	inducible knockdown cell line services for SHISA6
	design and validation of potent shRNA sequences against SHISA6
	adenovirus for potent knockdown of SHISA6
	adenovirus for overexpression of SHISA6
	stable overexpressing cell line services for SHISA6
	inducible overexpressing cell line services for SHISA6

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes SHISA6 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

SHISA6 Gene

shisa homolog 6 (Xenopus laevis)

Aliases
for SHISA6 gene

Summaries
for SHISA6 gene

Genomic Views
for SHISA6 gene

Proteins
for SHISA6 gene

Protein Domains /
Families
for SHISA6 gene

Function
for SHISA6 gene

Pathways & Interactions
for SHISA6 gene

Drugs & Compounds
for SHISA6 gene

Transcripts
for SHISA6 gene

Expression
for SHISA6 gene

Orthologs
for SHISA6 gene

Paralogs
for SHISA6 gene

Genomic Variants
for SHISA6 gene

Disorders / Diseases
for SHISA6 gene

Publications
for SHISA6 gene

External Searches for SHISA6 gene

Genome Databases showing SHISA6 gene

Other Databases showing SHISA6 gene

Specialized Databases showing SHISA6 gene

Intellectual Property
for SHISA6 gene

Products
for SHISA6 gene

View Random Gene

Advanced Search

Export list of displayed genes

SHISA6 Gene

shisa homolog 6 (Xenopus laevis)

Aliasesfor SHISA6 gene

Summariesfor SHISA6 gene

Genomic Viewsfor SHISA6 gene

Proteinsfor SHISA6 gene

Protein Domains /Familiesfor SHISA6 gene

Functionfor SHISA6 gene

Pathways & Interactionsfor SHISA6 gene

Drugs & Compoundsfor SHISA6 gene

Transcriptsfor SHISA6 gene

Expression for SHISA6 gene

Orthologsfor SHISA6 gene

Paralogsfor SHISA6 gene

Genomic Variantsfor SHISA6 gene

Disorders / Diseasesfor SHISA6 gene

Publicationsfor SHISA6 gene

External Searches for SHISA6 gene

Genome Databases showing SHISA6 gene

Other Databases showing SHISA6 gene

Specialized Databases showing SHISA6 gene

Intellectual Propertyfor SHISA6 gene

Productsfor SHISA6 gene

View Random Gene

Aliases
for SHISA6 gene

Summaries
for SHISA6 gene

Genomic Views
for SHISA6 gene

Proteins
for SHISA6 gene

Protein Domains /
Families
for SHISA6 gene

Function
for SHISA6 gene

Pathways & Interactions
for SHISA6 gene

Drugs & Compounds
for SHISA6 gene

Transcripts
for SHISA6 gene

Expression
for SHISA6 gene

Orthologs
for SHISA6 gene

Paralogs
for SHISA6 gene

Genomic Variants
for SHISA6 gene

Disorders / Diseases
for SHISA6 gene

Publications
for SHISA6 gene

Intellectual Property
for SHISA6 gene

Products
for SHISA6 gene