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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SHF Gene

protein-coding   GIFtS: 48
GCID: GC15M045459

Src Homology 2 Domain Containing F

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Src Homology 2 Domain Containing F1 2
SH2 Domain-Containing Adapter Protein F2

External Ids:    HGNC: 251161   Entrez Gene: 905252   Ensembl: ENSG000001386067   UniProtKB: Q7M4L63   

Export aliases for SHF gene to outside databases

Previous GC identifers: GC15M043247 GC15M022283


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SHF Gene: 
SHF (Src homology 2 domain containing F) is a protein-coding gene. Diseases associated with SHF include otitis externa, and diastolic heart failure. An important paralog of this gene is SHE.

UniProtKB/Swiss-Prot: SHF_HUMAN, Q7M4L6
Function: Adapter protein which may play a role in the regulation of apoptosis in response to PDGF




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NT_010194.17  NC_018926.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SHF gene promoter:
         LHX3b/Lhx3b   RP58   p53   Egr-1   CUTL1   MIF-1   Nkx2-5   POU2F1   POU2F1a   LHX3a/Lhx3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSHF promoter sequence
   Search SABiosciences Chromatin IP Primers for SHF

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SHF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q21.1   Ensembl cytogenetic band:  15q21.1   HGNC cytogenetic band: 15q21.1

SHF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SHF gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M045459:  view genomic region     (about GC identifiers)

Start:
45,459,412 bp from pter      End:
45,493,373 bp from pter
Size:
33,962 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SHF_HUMAN, Q7M4L6 (See protein sequence)
Recommended Name: SH2 domain-containing adapter protein F  
Size: 423 amino acids; 46768 Da
Subunit: Interacts with phosphorylated 'Tyr-720' of PDGFRA via its SH2 domain
Miscellaneous: The sequence described in PubMed:11095946 is over-extended by 57 aa at the N-terminus due to the
presence of an uncorrected 5' mismatch compared to the reference genome sequence
Secondary accessions: Q96IE8
Alternative splicing: 2 isoforms:  Q7M4L6-1   Q7M4L6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SHF: NX_Q7M4L6

Explore proteomics data for SHF at MOPED 

Post-translational modifications:

  • UniProtKB: May become phosphorylated upon binding to PDGFRA
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7M4L6

  • SHF Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SHF Protein Expression
    REFSEQ proteins: NP_612365.2  
    ENSEMBL proteins: 
     ENSP00000453370   ENSP00000290894   ENSP00000453168   ENSP00000411530   ENSP00000454034  
     ENSP00000453676   ENSP00000453260   ENSP00000452726   ENSP00000453827   ENSP00000453986  
     ENSP00000315978  

    Human Recombinant Protein Products for SHF: 
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    Cloud-Clone Corp. CLIAs for SHF


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SH2D: SH2 domain containing

    1 InterPro protein domain:
     IPR000980 SH2

    Graphical View of Domain Structure for InterPro Entry Q7M4L6

    ProtoNet protein and cluster: Q7M4L6

    1 Blocks protein domain: IPB000980 SH2 domain signature

    UniProtKB/Swiss-Prot: SHF_HUMAN, Q7M4L6
    Similarity: Contains 1 SH2 domain


    SHF for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SHF_HUMAN, Q7M4L6
    Function: Adapter protein which may play a role in the regulation of apoptosis in response to PDGF

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    SHF for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SHF 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SHF

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SHF 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SHF 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SHF
    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate SHF (see all 11):
    hsa-miR-3140-3p hsa-miR-128 hsa-miR-3681* hsa-miR-1203 hsa-miR-766 hsa-miR-3922-3p hsa-miR-3667-3p hsa-miR-211
    SwitchGear 3'UTR luciferase reporter plasmidSHF 3' UTR sequence
    Inhib. RNA
    Products:
        
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                         Customized lentivirus expression plasmids for stable overexpression of SHF 

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SHF


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SHF About                                                                                                See pathways by source

    SuperPathContained pathways About
    1PDGFR-alpha signaling pathway
    PDGFR-alpha signaling pathway


    1 BioSystems Pathway for SHF
        PDGFR-alpha signaling pathway


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SHF

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for SHF (ENSP000002908944) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PDGFRAENSP000002572904STRING: ENSP00000257290
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IEA--

    SHF for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SHF

    Search CenterWatch for drugs/clinical trials and news about SHF

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SHF gene: 
    NM_138356.2  

    Unigene Cluster for SHF:

    Src homology 2 domain containing F
    Hs.310399  [show with all ESTs]
    Unigene Representative Sequence: NM_138356
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000560540(uc010ueo.2) ENST00000290894(uc010uen.2 uc001zuy.3)
    ENST00000560734 ENST00000458022 ENST00000558294 ENST00000561239 ENST00000560471(uc010ues.1 uc010uet.1 uc010ueu.2)
    ENST00000559566 ENST00000558685 ENST00000561091 ENST00000561278 ENST00000318390

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SHF
    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate SHF (see all 11):
    hsa-miR-3140-3p hsa-miR-128 hsa-miR-3681* hsa-miR-1203 hsa-miR-766 hsa-miR-3922-3p hsa-miR-3667-3p hsa-miR-211
    SwitchGear 3'UTR luciferase reporter plasmidSHF 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SHF
    Sirion Biotech Customized lentivirus for stable overexpression of SHF 
                         Customized lentivirus expression plasmids for stable overexpression of SHF 
    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SHF

    Additional mRNA sequence: 

    AK096267.1 AK301625.1 AK303749.1 BC007586.1 BC101601.1 BC101603.1 BC143601.1 BC171730.1 

    12 DOTS entries:

    DT.408131  DT.95324355  DT.100746226  DT.100745034  DT.101955847  DT.100688005  DT.40131908  DT.432600 
    DT.75154511  DT.97825673  DT.97826029  DT.97824199 

    24/79 AceView cDNA sequences (see all 79):

    AA322771 BU727555 CR610652 NM_138356 AK094391 CR597455 CR613819 CR607464 
    BF445569 BM669861 BM673643 BM727200 F13153 CR626127 CR604168 BM712160 
    BC007586 AW157106 AK123658 BM681670 BM665833 AA323182 AA325868 BM478261 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for SHF (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c · 8d · 8e · 8f · 8g ^ 9 ^ 10a · 10b
    SP1:              -                                               -                       -     -     -     -               
    SP2:                                                              -                                                         
    SP3:                                      -     -                 -                                                         
    SP4:                                      -     -                 -                       -     -     -     -               
    SP5:                                                                                                                        


    ECgene alternative splicing isoforms for SHF

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SHF expression in normal human tissues (normalized intensities)      SHF embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCCTGCTCT
    SHF Expression
    About this image


    SHF expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Peripheral Nervous System (Nervous System)    fully expand to see all 3 entries
             autonomic/sympathetic/ganglion   
     
     Neuron (Nervous System)
             nerve   
     
     Spinal Cord (Nervous System)
             spinal/ganglion/dorsal root ganglion   
     
     Neural Tube (Nervous System)
             Metencephalon
     
     Brain (Nervous System)
             Cerebral Cortex

    See SHF Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SHF

    SOURCE GeneReport for Unigene cluster: Hs.310399

    UniProtKB/Swiss-Prot: SHF_HUMAN, Q7M4L6
    Tissue specificity: Expressed in skeletal muscle, brain, liver, prostate, testis, ovary, small intestine and colon

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SHF

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SHF gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Shf1 , 5 Src homology 2 domain containing F1, 5 92.72(n)1
    96.64(a)1
      2 (60.63 cM)5
    4356841  NM_001013829.21  NP_001013851.21 
     1223488925 
    chicken
    (Gallus gallus)
    Aves SHF1 Src homology 2 domain containing F 67.6(n)
    67.13(a)
      415339  XM_413725.2  XP_413725.2 
    lizard
    (Anolis carolinensis)
    Reptilia SHF6
    Uncharacterized protein
    49(a)
    1 ↔ 1
    GL343490.1(79865-85120)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ072127.12   -- 80.95(n)    BJ072127.1 
    zebrafish
    (Danio rerio)
    Actinopterygii SHF6
    Src homology 2 domain containing F
    75(a)
    1 ↔ 1
    18(49390432-49514397)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG439216
    --
    6(a)
    1 → many
    X(12410667-12462394)


    ENSEMBL Gene Tree for SHF (if available)
    TreeFam Gene Tree for SHF (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SHF gene
    SHE2  ENSG000002558722  SHD2  SHB2  
    4 SIMAP similar genes for SHF using alignment to 16 protein entries:     SHF_HUMAN (see all proteins):
    SHB    PTPN11    SHE    SHD

    SHF for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SHF
    PGOHUM00000262061


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/703 SNPs in SHF are shown (see all 703)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs17068151,2
    C,F,A,H--45458935(+) CCTCCG/CCGGGC 1 -- int11Minor allele frequency- C:0.50NA 2
    rs16483101,2
    C,F,A,H--45458954(-) CGCCCG/AGGCCT 1 -- int13Minor allele frequency- A:0.39NA 124
    rs71820811,2
    C--45459112(+) GCCAAG/AGAGAC 1 -- int13Minor allele frequency- A:0.27NA EA 242
    rs16483091,2
    C,F--45459182(-) CCTGCC/TACGCG 1 -- int14Minor allele frequency- T:0.38NA EA 126
    rs1825123451,2
    --45459262(+) GCTGTA/TGGCAG 1 -- int10--------
    rs71820071,2
    C--45459277(+) TTGGAA/CGCGCT 1 -- int10--------
    rs16299061,2
    C,F,A,H--45459564(-) CGGGCT/CAGAGG 1 -- ut31 ese320Minor allele frequency- C:0.49MN NS EA NA WA 2354
    rs1867001151,2
    --45459735(+) ACGGAA/GGCAGA 1 -- ut310--------
    rs1154257451,2
    C,F--45459760(+) CCCCAA/GGGGGC 1 -- ut311Minor allele frequency- G:0.02WA 118
    rs1908207861,2
    --45459788(+) CGCACC/GGACCC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SHF (45459412 - 45493373 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SHF:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv904187CNV Loss21882294
    nsv518213CNV Gain19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SHF
    DNA2.0 Custom Variant and Variant Library Synthesis for SHF

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    6 diseases for SHF:    About MalaCards
    otitis externa    diastolic heart failure    systolic heart failure    echinococcosis
    congestive heart failure    prostatitis

    1 disease from the University of Copenhagen DISEASES database for SHF:
    Congestive heart failure

    SHF for disorders           About GeneDecksing

    Genetic Association Database (GAD): SHF

    Export disorders for SHF gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SHF gene integrated from 9 sources:
    (articles sorted by number of sources associating them with SHF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Shf, a Shb-like adapter protein, is involved in PDGF-alpha-receptor regulation of apoptosis. (PubMed id 11095946)1, 2, 3 Lindholm C.K.... Welsh M. (2000)
    2. Novel adaptor protein Shf interacts with ALK receptor and negatively regulates its downstream signals in neuroblastoma. (PubMed id 23360421)1 Takagi D....Nakagawara A. (2013)
    3. Genome-wide association of serum uric acid concentrati on: replication of sequence variants in an island population of the Adriatic coa st of Croatia. (PubMed id 22229870)4 Karns R....Deka R. (2012)
    4. A genome-wide association study identifies a novel ma jor locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. (PubMed id 19875614)4 Paterson A.D....Bull S.B. (2010)
    5. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (2006)
    6. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 90525 HGNC: 25116 AceView: LOC90525 Ensembl:ENSG00000138606 euGenes: HUgn90525
    ECgene: SHF H-InvDB: SHF

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SHF Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SHF gene:
    Search GeneIP for patents involving SHF

    GeneCards and IP:
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