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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SHANK1 Gene

protein-coding   GIFtS: 55
GCID: GC19M051165

SH3 and multiple ankyrin repeat domains 1

  Search for SHANK1
in our new
 Human Malady Compendium 
Biological research products
for SHANK1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
SH3 And Multiple Ankyrin Repeat Domains 11 2     Somatostatin Receptor-Interacting Protein2 3
SSTRIP1 2 3     SSTR-Interacting Protein2 3
SPANK-11 2     SH3 And Multiple Ankyrin Repeat Domains Protein 12
Synamon1     Shank13

External Ids:    HGNC: 154741   Entrez Gene: 509442   Ensembl: ENSG000001616817   OMIM: 6049995   UniProtKB: Q9Y5663   

Export aliases for SHANK1 gene to outside databases

Previous GC identifers: GC19M051793 GC19M051526 GC19M055841 GC19M055856 GC19M055818 GC19M047499


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: SHAN1_HUMAN, Q9Y566
Function: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects
receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with
GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional
organization of the dendritic spine and synaptic junction

Gene Wiki entry for SHANK1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SHANK1 gene promoter:
         Max1   Pax-5   Tal-1   AP-1   NRSF form 1   STAT5A   NRSF form 2   E47   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SHANK1 promoter sequence
   Search SABiosciences Chromatin IP Primers for SHANK1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SHANK1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.3   Ensembl cytogenetic band:  19q13.33   HGNC cytogenetic band: 19q13.3

SHANK1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SHANK1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M051165:  view genomic region     (about GC identifiers)

Start:
51,165,084 bp from pter      End:
51,222,707 bp from pter
Size:
57,624 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SHAN1_HUMAN, Q9Y566 (See protein sequence)
Recommended Name: SH3 and multiple ankyrin repeat domains protein 1  
Size: 2161 amino acids; 224959 Da
Subunit: May homomultimerize via its SAM domain (By similarity). Interacts with the C-terminus of SSTR2 via the PDZ
domain. Interacts with IGSF9, SHARPIN, SPTAN1, HOMER1 and DLGAP1/GKAP isoforms 1 and 2 (By similarity). Part of a
complex with DLG4/PSD-95 and DLGAP1/GKAP (By similarity). Interacts with BAIAP2
Subcellular location: Cytoplasm (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic
density (By similarity). Cell junction, synapse (By similarity). Note=Postsynaptic density of neuronal cells (By
similarity)
Secondary accessions: A8MXP5 B7WNY6 Q9NYW9
Alternative splicing: 3 isoforms:  Q9Y566-1   Q9Y566-2   Q9Y566-3   

Explore the universe of human proteins at neXtProt for SHANK1: NX_Q9Y566

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9Y566

  • SHANK1 Protein expression data from MOPED and PaxDb:    About this image 
    SHANK1 Protein Expression
    REFSEQ proteins: NP_057232.2  
    ENSEMBL proteins: 
     ENSP00000293441   ENSP00000375689   ENSP00000375690   ENSP00000351984  

    Human Recombinant Protein Products for SHANK1: 
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    Uscn Proteins for SHANK1

    Gene Ontology (GO): 5/15 cellular component terms (GO ID links to tree view) (see all 15):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular NAS10551867
    GO:0005624membrane fraction ----
    GO:0005737cytoplasm IEA--
    GO:0005886plasma membrane ISS--
    GO:0008328colocalizes with ionotropic glutamate receptor complex ISS--

    SHANK1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for SHANK1


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    SHANK1 for domains           About GeneDecksing

    5/8 InterPro domains/families (see all 8):
     IPR011511 SH3_2
     IPR013761 SAM/pointed
     IPR001660 SAM
     IPR001478 PDZ
     IPR021129 SAM_type1

    Graphical View of Domain Structure for InterPro Entry Q9Y566

    ProtoNet protein and cluster: Q9Y566

    5 Blocks protein families:
    IPB001452 SH3 domain signature
    IPB001478 PDZ/DHR/GLGF domain
    IPB001660 Sterile alpha motif SAM
    IPB002110 Ankyrin repeat signature
    IPB011511 Variant SH3


    UniProtKB/Swiss-Prot: SHAN1_HUMAN, Q9Y566
    Similarity: Belongs to the SHANK family
    Similarity: Contains 6 ANK repeats
    Similarity: Contains 1 PDZ (DHR) domain
    Similarity: Contains 1 SAM (sterile alpha motif) domain
    Similarity: Contains 1 SH3 domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SHAN1_HUMAN, Q9Y566
    Function: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects
    receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with
    GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional
    organization of the dendritic spine and synaptic junction

         Gene Ontology (GO): 5/11 molecular function terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI11583995
    GO:0008022protein C-terminus binding IEA--
    GO:0017124SH3 domain binding ISS--
    GO:0030159receptor signaling complex scaffold activity ----
    GO:0030160GKAP/Homer scaffold activity ISS--
         
    SHANK1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SHANK1:
     Decreased homologous recombina 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Shank1):
     behavior/neurological  nervous system  reproductive system 

    SHANK1 for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-out Shank1tm1Shng for SHANK1
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SHANK1 

    miRNA
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    hsa-miR-4257
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SHANK1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cytoskeleton remodeling Neurofilaments
    Cytoplasmic microtubules0.32
    2Opioid Signalling
    Glutamatergic synapse0.31

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for SHANK1
        Cytoplasmic microtubules



    1         Kegg Pathway  (Kegg details for SHANK1):
        Glutamatergic synapse


    SHANK1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SHANK1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    5/40 Interacting proteins for SHANK1 (Q9Y5662, 3 ENSP000002934414) via UniProtKB, MINT, STRING, and/or I2D (see all 40)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LPHN2O954902, 3, ENSP000003222704MINT-72956 I2D: score=3 STRING: ENSP00000322270
    DLGAP1O144902, 3, ENSP000003163774MINT-7894188 I2D: score=6 STRING: ENSP00000316377
    BAI2O602412, 3, ENSP000003627624MINT-72957 I2D: score=3 STRING: ENSP00000362762
    DLG4P783523, ENSP000002938134I2D: score=4 STRING: ENSP00000293813
    ARHGEF7Q141553, ENSP000003648934I2D: score=3 STRING: ENSP00000364893
    About this table

    Gene Ontology (GO): 5/18 biological process terms (GO ID links to tree view) (see all 18):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006461protein complex assembly ISS--
    GO:0007016cytoskeletal anchoring at plasma membrane NAS10551867
    GO:0007616long-term memory ISS--
    GO:0008306associative learning ISS--
    GO:0032232negative regulation of actin filament bundle assembly IEA--

    SHANK1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SHANK1
    Search CenterWatch for drugs/clinical trials and news about SHANK1 / SHAN1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SHANK1 gene: 
    NM_016148.2  

    Unigene Cluster for SHANK1:

    SH3 and multiple ankyrin repeat domains 1
    Hs.274255  [show with all ESTs]
    Unigene Representative Sequence: AF163302
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000293441(uc002psx.1) ENST00000391813(uc002psw.1) ENST00000391814(uc010yce.1)
    ENST00000483981 ENST00000468654 ENST00000461154 ENST00000483128 ENST00000359082


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    hsa-miR-4257
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    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SHANK1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SHANK1

    Additional cDNA sequence: 

    AF163302.1 AF226728.1 

    4 DOTS entries:

    DT.92419193  DT.121486651  DT.92419190  DT.91699571 

    24 AceView cDNA sequences:

    AI554563 BF969037 BV196293 BF770520 BM475356 NM_016148 BF970858 CK299116 
    AY461451 BF771112 AF226728 BX283115 AF163302 BI196108 BQ422598 BE258286 
    R88191 AW900154 AW857250 BG251239 CK000629 BF952105 BI195188 BE066122 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for SHANK1 (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18
    SP1:                                                                                                            
    SP2:                                                                                                            
    SP3:                                                  -                                                         
    SP4:                                                                                                            
    SP5:                                                                                                            


    ECgene alternative splicing isoforms for SHANK1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SHANK1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AACATCGACC
    SHANK1 Expression
    About this image
    See SHANK1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SHANK1

    SOURCE GeneReport for Unigene cluster: Hs.274255

    UniProtKB/Swiss-Prot: SHAN1_HUMAN, Q9Y566
    Tissue specificity: Expressed in brain particularly in the amygdala, hippocampus, substantia nigra and thalamus.
    Isoform 2 seems to be expressed ubiquitously

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SHANK1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SHANK1 gene from 6/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Shank11 , 5 SH3/ankyrin domain gene 11, 5 86.08(n)1
    94.29(a)1
      7 (28.83 cM)5
    2439611  NM_001034115.11  NP_001029287.11 
     443102535 
    chicken
    (Gallus gallus)
    Aves SHANK36
    Uncharacterized protein
    60(a)
    1 ↔ 1
    1(171647-199289)
    lizard
    (Anolis carolinensis)
    Reptilia SHANK16
    --
    62(a)
    1 ↔ 1
    6(79339365-79427671)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5689081 uncharacterized LOC568908 56.67(n)
    56.97(a)
      568908  XM_003198122.1  XP_003198170.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Prosap6
    Prosap
    19(a)
    1 → many
    2R(9947961-10028403)
    worm
    (Caenorhabditis elegans)
    Secernentea C33B4.33 ankyrin and proline rich domains 44(a)   II(11384828-11390687)   --


    ENSEMBL Gene Tree for SHANK1 (if available)
    TreeFam Gene Tree for SHANK1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SHANK1 gene
    SHANK22  
    3 SIMAP similar genes for SHANK1 using alignment to 3 protein entries:     SHAN1_HUMAN (see all proteins):
    ARHGEF7    SHANK2    ARHGAP23

    SHANK1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1098 NCBI SNPs in SHANK1 are shown (see all 1098    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs358684521,2
    C--47511900(+) TTTTT-/TGAGAC 1 -- int11Minor allele frequency- T:0.00NA 2
    rs1480253551,2
    --51164597(+) GTGTAC/TTTGAG 1 -- ds50010--------
    rs1417261841,2
    --51164610(+) GGCCTC/TGCCAG 1 -- ds50010--------
    rs1833500051,2
    --51164646(+) GACAGC/TGAGAG 1 -- ds50010--------
    rs1872477571,2
    --51164683(+) GGGGAC/TGGGAG 1 -- ds50010--------
    rs786427141,2
    C--51164803(+) GGAAGG/AGTTGT 1 -- ds50014Minor allele frequency- A:0.11NA WA EA 360
    rs1502263221,2
    --51164855(+) CCCTGC/TGGCCT 1 -- ds50010--------
    rs1175716951,2
    F--51164981(+) TCCCCC/ACTCCG 1 -- ds50011Minor allele frequency- A:0.02NA 120
    rs1388013541,2
    --51164985(+) CCCTCC/TGCTCC 1 -- ds50010--------
    rs2011598521,2
    --51164996(+) CCGCT-/TCACACA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for SHANK1 (51165084 - 51222707 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SHANK1: --
    Human Gene Mutation Database (HGMD): SHANK1

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SHANK1 for disorders           About MalaCards

    SHANK1 for disorders           About GeneDecksing

    OMIM gene information: 604999    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for SHANK1:
    Autistic disorder

    Export disorders for SHANK1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SHANK1 gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with SHANK1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Somatostatin receptor interacting protein defines a novel family of multidomain proteins present in human and rodent brain. (PubMed id 10551867)1, 2, 3, 9 Zitzer H.... Kreienkamp H.-J. (1999)
    2. The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42. (PubMed id 12504591)1, 2 Soltau M.... Kreienkamp H.-J. (2002)
    3. The Shank family of scaffold proteins. (PubMed id 10806096)1, 2 Sheng M. and Kim E. (2000)
    4. Shank1 mRNA: dendritic transport by kinesin and trans lational control by the 5'untranslated region. (PubMed id 19416473)1, 9 Falley K....Kreienkamp H.J. (2009)
    5. Identification of proteins interacting with the rat somatostatin receptor subtype 2. (PubMed id 11087996)1, 9 Kreienkamp H.J....Richter D. (2000)
    6. A promoter variant of SHANK1 affects auditory working memory in schizophrenia patients and in subjects clinically at risk for psychosi s. (PubMed id 21901269)1 Lennertz L....Mossner R. (2012)
    7. SHANK1 Deletions in Males with Autism Spectrum Disorde r. (PubMed id 22503632)1 Sato D....Scherer S.W. (2012)
    8. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
    9. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    10. Ribosomal S6 kinase 2 interacts with and phosphorylates PDZ domain-containing proteins and regulates AMPA receptor transmission. (PubMed id 16217014)1 Thomas G.M....Huganir R.L. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 50944 HGNC: 15474 AceView: SHANK1 Ensembl:ENSG00000161681 euGenes: HUgn50944
    ECgene: SHANK1 Kegg: 50944 H-InvDB: SHANK1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SHANK1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SHANK1 gene:
    Search GeneIP for patents involving SHANK1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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