SHANK1 Gene
protein-coding GIFtS: 55
GCID: GC19M051165
|
|
SH3 and multiple ankyrin repeat domains 1
| |
Aliases for SHANK1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| SH3 And Multiple Ankyrin Repeat Domains 11 2 | | Somatostatin Receptor-Interacting Protein2 3 | | SSTRIP1 2 3 | | SSTR-Interacting Protein2 3 | | SPANK-11 2 | | SH3 And Multiple Ankyrin Repeat Domains Protein 12 | | Synamon1 | | Shank13 |
Export aliases for SHANK1 gene to outside databasesPrevious GC identifers: GC19M051793 GC19M051526 GC19M055841 GC19M055856 GC19M055818 GC19M047499 |
Summaries for SHANK1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: SHAN1_HUMAN, Q9Y566Function: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnectsreceptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes withGKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functionalorganization of the dendritic spine and synaptic junction Gene Wiki entry for SHANK1
|
Genomic Views for SHANK1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SHANK1 gene promoter: Max1 Pax-5 Tal-1 AP-1 NRSF form 1 STAT5A NRSF form 2 E47 c-Myc Other transcription factors
Search SABiosciences Chromatin IP Primers for SHANK1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SHANK1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.3 Ensembl cytogenetic band: 19q13.33 HGNC cytogenetic band: 19q13.3SHANK1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M051165: view genomic region
(about GC identifiers)
Start:
|
51,165,084 bp from pter |
End:
|
51,222,707 bp from pter |
Size:
|
57,624 bases |
Orientation:
|
minus strand |
|
Proteins for SHANK1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SHAN1_HUMAN, Q9Y566 (See
protein sequence)Recommended Name: SH3 and multiple ankyrin repeat domains protein 1 Size: 2161 amino acids; 224959 Da
Subunit: May homomultimerize via its SAM domain (By similarity). Interacts with the C-terminus of SSTR2 via the PDZdomain. Interacts with IGSF9, SHARPIN, SPTAN1, HOMER1 and DLGAP1/GKAP isoforms 1 and 2 (By similarity). Part of acomplex with DLG4/PSD-95 and DLGAP1/GKAP (By similarity). Interacts with BAIAP2
Subcellular location: Cytoplasm (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynapticdensity (By similarity). Cell junction, synapse (By similarity). Note=Postsynaptic density of neuronal cells (Bysimilarity)
Secondary accessions: A8MXP5 B7WNY6 Q9NYW9Alternative splicing: 3 isoforms: Q9Y566-1 Q9Y566-2 Q9Y566-3 Explore the universe of human proteins at neXtProt for SHANK1: NX_Q9Y566
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y566 SHANK1 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins: NP_057232.2 ENSEMBL proteins: ENSP00000293441 ENSP00000375689 ENSP00000375690 ENSP00000351984 Human Recombinant Protein Products for SHANK1:
Gene Ontology (GO): 5/15 cellular component terms (GO ID links to tree view) (see all 15): About this table
SHANK1 for ontologies About GeneDecksing
SHANK1 Antibody Products: Assay Products for SHANK1: |
Protein
Domains / Families for SHANK1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SHANK1 for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry Q9Y566ProtoNet protein and cluster: Q9Y566 5 Blocks protein families: IPB001452 SH3 domain signature IPB001478 PDZ/DHR/GLGF domain IPB001660 Sterile alpha motif SAM IPB002110 Ankyrin repeat signature IPB011511 Variant SH3
UniProtKB/Swiss-Prot: SHAN1_HUMAN, Q9Y566Similarity: Belongs to the SHANK familySimilarity: Contains 6 ANK repeatsSimilarity: Contains 1 PDZ (DHR) domainSimilarity: Contains 1 SAM (sterile alpha motif) domainSimilarity: Contains 1 SH3 domain |
Function for SHANK1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: SHAN1_HUMAN, Q9Y566Function: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnectsreceptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes withGKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functionalorganization of the dendritic spine and synaptic junction Gene Ontology (GO): 5/11 molecular function terms (GO ID links to tree view) (see all 11): About this table
SHANK1 for ontologies About GeneDecksing
Phenotypes: 1 GenomeRNAi human phenotype for SHANK1: 3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Shank1):
SHANK1 for phenotypes About GeneDecksing
Animal Models: Mouse knock-out Shank1tm1Shng for SHANK1
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SHANK1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SHANK1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SHANK1 (NM_016148) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SHANK1 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SHANK1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SHANK1 |
|
Pathways & Interactions for SHANK1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cytoskeleton remodeling Neurofilaments | | | 2 | Opioid Signalling | |
Pathway sources See GeneCards unified pathways Show all pathways
1 EMD Millipore Pathway for SHANK1
1
Kegg Pathway (Kegg details for SHANK1):
SHANK1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SHANK1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 24)
 5/40 Interacting proteins for SHANK1 (Q9Y5662, 3 ENSP000002934414) via UniProtKB, MINT, STRING, and/or I2D (see all 40)About this table
Gene Ontology (GO): 5/18 biological process terms (GO ID links to tree view) (see all 18): About this table
SHANK1 for ontologies About GeneDecksing
|
Drugs & Compounds for SHANK1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for SHANK1 Search CenterWatch for drugs/clinical trials and news about SHANK1 / SHAN1 
|
Transcripts for SHANK1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SHANK1 gene: NM_016148.2 Unigene Cluster for SHANK1: SH3 and multiple ankyrin repeat domains 1 Hs.274255 [show with all ESTs]Unigene Representative Sequence: AF1633028 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000293441(uc002psx.1) ENST00000391813(uc002psw.1) ENST00000391814(uc010yce.1) ENST00000483981 ENST00000468654 ENST00000461154 ENST00000483128 ENST00000359082
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SHANK1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SHANK1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SHANK1 (NM_016148) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SHANK1 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SHANK1  |
Additional cDNA sequence: AF163302.1 AF226728.1 4 DOTS entries: DT.92419193 DT.121486651 DT.92419190 DT.91699571 24 AceView cDNA sequences: AI554563 BF969037 BV196293 BF770520 BM475356 NM_016148 BF970858 CK299116 AY461451 BF771112 AF226728 BX283115 AF163302 BI196108 BQ422598 BE258286 R88191 AW900154 AW857250 BG251239 CK000629 BF952105 BI195188 BE066122 GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for SHANK1 (see all 7) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for SHANK1
|
Expression for SHANK1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SHANK1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: AACATCGACC
 About this image See SHANK1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SHANK1
SOURCE GeneReport for Unigene cluster: Hs.274255
UniProtKB/Swiss-Prot: SHAN1_HUMAN, Q9Y566Tissue specificity: Expressed in brain particularly in the amygdala, hippocampus, substantia nigra and thalamus.Isoform 2 seems to be expressed ubiquitously SABiosciences Custom PCR Arrays for SHANK1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SHANK1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SHANK1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SHANK1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SHANK1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SHANK1 |
Orthologs for SHANK1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SHANK1 gene from 6/16 species (see all 16) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Shank11 , 5 |
SH3/ankyrin domain gene 11, 5 |
86.08(n)1 94.29(a)1 |
  |
7 (28.83 cM)5 2439611 NM_001034115.11 NP_001029287.11 443102535 |
chicken (Gallus gallus) |
Aves |
SHANK36 |
Uncharacterized protein |
60(a) |
1 ↔ 1 |
1(171647-199289) |
lizard (Anolis carolinensis) |
Reptilia |
SHANK16 |
-- |
62(a) |
1 ↔ 1 |
6(79339365-79427671) |
zebrafish (Danio rerio) |
Actinopterygii |
LOC5689081 |
uncharacterized LOC568908 |
56.67(n) 56.97(a) |
  |
568908 XM_003198122.1 XP_003198170.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
Prosap6 |
Prosap |
19(a) |
1 → many |
2R(9947961-10028403) |
worm (Caenorhabditis elegans) |
Secernentea |
C33B4.33 |
ankyrin and proline rich domains |
44(a) |
  |
II(11384828-11390687) -- |
ENSEMBL Gene Tree for SHANK1 (if available) TreeFam Gene Tree for SHANK1 (if available)  |
Paralogs for SHANK1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for SHANK1 gene
- SHANK22
3 SIMAP similar genes for SHANK1 using alignment to 3 protein entries: SHAN1_HUMAN (see all proteins):ARHGEF7 SHANK2 ARHGAP23
SHANK1 for paralogs About GeneDecksing
|
Genomic Variants for SHANK1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 19 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for SHANK1 (51165084 - 51222707 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for SHANK1: -- Human Gene Mutation Database (HGMD): SHANK1
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SHANK1 |
|
Disorders
/ Diseases for SHANK1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SHANK1 for disorders About MalaCards
SHANK1 for disorders About GeneDecksing
OMIM gene information: 604999
OMIM disorders: --
1 disease from the University of Copenhagen DISEASES database for SHANK1:Autistic disorder Export disorders for SHANK1 gene to outside databases
|
Publications for SHANK1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SHANK1 gene, integrated from 9 sources (see all 27): (articles sorted by number of sources associating them with SHANK1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Somatostatin receptor interacting protein defines a novel family of multidomain proteins present in human and rodent brain. (PubMed id 10551867)1, 2, 3, 9 Zitzer H.... Kreienkamp H.-J. (1999)
- The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42. (PubMed id 12504591)1, 2 Soltau M.... Kreienkamp H.-J. (2002)
- The Shank family of scaffold proteins. (PubMed id 10806096)1, 2 Sheng M. and Kim E. (2000)
- Shank1 mRNA: dendritic transport by kinesin and trans lational control by the 5'untranslated region. (PubMed id 19416473)1, 9 Falley K....Kreienkamp H.J. (2009)
- Identification of proteins interacting with the rat somatostatin receptor subtype 2. (PubMed id 11087996)1, 9 Kreienkamp H.J....Richter D. (2000)
- A promoter variant of SHANK1 affects auditory working memory in schizophrenia patients and in subjects clinically at risk for psychosi s. (PubMed id 21901269)1 Lennertz L....Mossner R. (2012)
- SHANK1 Deletions in Males with Autism Spectrum Disorde r. (PubMed id 22503632)1 Sato D....Scherer S.W. (2012)
- A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
- Ribosomal S6 kinase 2 interacts with and phosphorylates PDZ domain-containing proteins and regulates AMPA receptor transmission. (PubMed id 16217014)1 Thomas G.M....Huganir R.L. (2005)
|
External Searches for SHANK1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SHANK1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SHANK1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SHANK1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for SHANK1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SHANK1 gene: Search GeneIP for patents involving SHANK1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for SHANK1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
 |
| | | | OriGene Antibodies for SHANK1 | | OriGene shRNA RFP for SHANK1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SHANK1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SHANK1 | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for SHANK1 | | OriGene 3'-UTR Clone for SHANK1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SHANK1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SHANK1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for SHANK1 | | OriGene Custom Protein Services for SHANK1 | | OriGene Custom Immunoassay Development | | |
| |  |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SHANK1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SHANK1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SHANK1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SHANK1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SHANK1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SHANK1 |
| |
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| | | Search Tocris compounds for SHANK1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | SHANK1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SHANK1 |
|  |  |  |  | | | ThermoFisher Antibodies for SHANK1 |
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