Aliases for SHANK1 Gene
External Ids for SHANK1 Gene
Previous GeneCards Identifiers for SHANK1 Gene
GeneCards Summary for SHANK1 Gene
SHANK1 (SH3 And Multiple Ankyrin Repeat Domains 1) is a Protein Coding gene. Among its related pathways are Circadian entrainment. GO annotations related to this gene include identical protein binding and SH3 domain binding. An important paralog of this gene is SHANK2.
UniProtKB/Swiss-Prot for SHANK1 Gene
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction