Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SH3RF3 Gene

protein-coding   GIFtS: 46
GCID: GC02P109745

SH3 Domain Containing Ring Finger 3

(Previous name: SH3 multiple domains 4)
(Previous symbol: SH3MD4)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
SH3 Domain Containing Ring Finger 31 2     Plenty Of SH3s-22
SH3MD41 2 3     SH3 Domain-Containing RING Finger Protein 32
SH3 Multiple Domains 41 2     SH3 Multiple Domains Protein 43
Plenty Of SH3s 22 3     EC 6.3.28
POSH22 3     

External Ids:    HGNC: 246991   Entrez Gene: 3445582   Ensembl: ENSG000001729857   UniProtKB: Q8TEJ33   

Export aliases for SH3RF3 gene to outside databases

Previous GC identifers: GC02P109104 GC02P109381 GC02P109616 GC02P103343


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for SH3RF3 Gene:
SH3RF3 (SH3 domain containing ring finger 3) is a protein-coding gene. An important paralog of this gene is SH3RF2.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SH3RF3 gene promoter:
         Max1   HFH-3   AML1a   Egr-4   HEN1   FOXI1   FAC1   Cart-1   ZIC2/Zic2   c-Myc   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for SH3RF3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SH3RF3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q13   Ensembl cytogenetic band:  2q12.3   HGNC cytogenetic band: 2q13

SH3RF3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SH3RF3 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P109745:  view genomic region     (about GC identifiers)

Start:
109,745,804 bp from pter      End:
110,262,207 bp from pter
Size:
516,404 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: SH3R3_HUMAN, Q8TEJ3 (See protein sequence)
Recommended Name: SH3 domain-containing RING finger protein 3  
Size: 882 amino acids; 92776 Da
Subunit: Interacts with PAK2
Secondary accessions: A0SDZ7 A8MPR1 Q8NDU1

Explore the universe of human proteins at neXtProt for SH3RF3: NX_Q8TEJ3

Explore proteomics data for SH3RF3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 3 DME Specific Peptides for SH3RF3 (Q8TEJ3)
     RVDENWAEG  TGLFPGSFV  AKVLPCQHTFC 


    See SH3RF3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001092759.1  
    ENSEMBL proteins: 
     ENSP00000414997   ENSP00000390685   ENSP00000309186  

    SH3RF3 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for SH3RF3
    OriGene Protein Over-expression Lysate for SH3RF3
    OriGene MassSpec for SH3RF3
    OriGene Custom Protein Services for SH3RF3
    GenScript Custom Purified and Recombinant Proteins Services for SH3RF3
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SH3RF3

     
    Search eBioscience for Proteins for SH3RF3 

     
    Search antibodies-online for proteins for SH3RF3 

     
    antibodies-online peptides for SH3RF3

    SH3RF3 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for SH3RF3
    OriGene Custom Antibody Services for SH3RF3
    Novus Biologicals SH3RF3 Antibodies
    Abcam antibodies for SH3RF3
    Cloud-Clone Corp. Antibodies for SH3RF3
    Search ThermoFisher Antibodies for SH3RF3
    antibodies-online antibodies for SH3RF3 (13 products) 

    SH3RF3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SH3RF3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SH3RF3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SH3RF3
    Cloud-Clone Corp. CLIAs for SH3RF3
    Search eBioscience for ELISAs for SH3RF3 
    antibodies-online kits for SH3RF3 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    RNF: RING-type (C3HC4) zinc fingers

    Selected InterPro protein domains (see all 6):
     IPR001841 Znf_RING
     IPR001452 SH3_domain
     IPR013083 Znf_RING/FYVE/PHD
     IPR017907 Znf_RING_CS
     IPR028511 POSH2

    Graphical View of Domain Structure for InterPro Entry Q8TEJ3

    ProtoNet protein and cluster: Q8TEJ3

    UniProtKB/Swiss-Prot: SH3R3_HUMAN, Q8TEJ3
    Domain: The third SH3 domain mediates interaction with PAK2
    Similarity: Belongs to the SH3RF family
    Similarity: Contains 1 RING-type zinc finger
    Similarity: Contains 4 SH3 domains


    Find genes that share domains with SH3RF3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Enzyme Number (IUBMB): EC 6.3.22

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16374509
    GO:0008270zinc ion binding IEA--
         
    Find genes that share ontologies with SH3RF3           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for SH3RF3

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat SH3RF3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SH3RF3 (see all 40):
    hsa-miR-579 hsa-miR-142-5p hsa-let-7d hsa-miR-548k hsa-miR-4305 hsa-miR-29a hsa-miR-192 hsa-miR-3171
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SH3RF3
    Predesigned siRNA for gene silencing in human, mouse, rat SH3RF3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SH3RF3

    Clone
    Products:
         
    OriGene clones in human, mouse for SH3RF3 (see all 6)
    OriGene ORF clones in mouse, rat for SH3RF3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SH3RF3 (NM_001099289)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SH3RF3
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SH3RF3

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SH3RF3
    Browse ESI BIO Cell Lines and PureStem Progenitors for SH3RF3 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3RF3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SH3RF3
    Interactions:

        Search GeneGlobe Interaction Network for SH3RF3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for SH3RF3 (Q8TEJ31, 2, 3 ENSP000003091864) via UniProtKB, MINT, STRING, and/or I2D (see all 29)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PAK2Q131771, 2, 3, ENSP000003140674EBI-7975674,EBI-1045887 MINT-2792893 MINT-2792283 I2D: score=2 STRING: ENSP00000314067
    ADAM15Q134442, 3, ENSP000003494364MINT-2792701 I2D: score=2 STRING: ENSP00000349436
    RAC1P630001, 2, 3, ENSP000003484614EBI-7975674,EBI-413628 MINT-7987880 MINT-7987779 MINT-7987824 MINT-7987838 MINT-7987804 MINT-7987853 I2D: score=1 STRING: ENSP00000348461
    UBCP0CG482, 3, ENSP000003448184MINT-7987734 I2D: score=1 STRING: ENSP00000344818
    GPN2ENSP000003632504STRING: ENSP00000363250
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SH3RF3 (SH3R3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SH3RF3 gene: 
    NM_001099289.2  

    Unigene Clusters for SH3RF3:

    SH3 domain containing ring finger 3
    Hs.171244  [show with all ESTs], Hs.535157  [show with all ESTs]
    Unigene Representative Sequences: NR_029193, NM_001099289
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000418513 ENST00000444352 ENST00000309415(uc010ywt.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SH3RF3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SH3RF3 (see all 40):
    hsa-miR-579 hsa-miR-142-5p hsa-let-7d hsa-miR-548k hsa-miR-4305 hsa-miR-29a hsa-miR-192 hsa-miR-3171
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SH3RF3
    Predesigned siRNA for gene silencing in human, mouse, rat SH3RF3
    Clone
    Products:
         
    OriGene clones in human, mouse for SH3RF3 (see all 6)
    OriGene ORF clones in mouse, rat for SH3RF3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SH3RF3 (NM_001099289)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SH3RF3
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SH3RF3
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SH3RF3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SH3RF3
      QuantiTect SYBR Green Assays in human, mouse, rat SH3RF3
      QuantiFast Probe-based Assays in human, mouse, rat SH3RF3

    Additional mRNA sequence: 

    AK074131.1 AK093821.1 AL831825.1 

    3 DOTS entries:

    DT.314964  DT.97838784  DT.92343438 

    1 AceView cDNA sequence:

    AI214759 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SH3RF3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGCCTGTGT
    SH3RF3 Expression
    About this image


    SH3RF3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Eye (Sensory Organs)
             Retina
     
     Spinal Cord (Nervous System)
     
     Brain (Nervous System)
    SH3RF3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SH3RF3 Protein Expression

    SOURCE GeneReport for Unigene clusters: Hs.171244 Hs.535157
        Custom PCR Arrays for SH3RF3
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for SH3RF3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SH3RF3
    QuantiTect SYBR Green Assays in human, mouse, rat SH3RF3
    QuantiFast Probe-based Assays in human, mouse, rat SH3RF3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3RF3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for SH3RF3 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sh3rf31 , 5 SH3 domain containing ring finger 31, 5 82.42(n)1
    83.3(a)1
      10 (29.41 cM)5
    2373531  NM_172788.31  NP_766376.21 
     588133595 
    chicken
    (Gallus gallus)
    Aves SH3RF31 SH3 domain containing ring finger 3 74.8(n)
    76.78(a)
      418731  XM_416930.4  XP_416930.4 
    lizard
    (Anolis carolinensis)
    Reptilia SH3RF36
    SH3 domain containing ring finger 3
    65(a)
    1 ↔ 1
    3(106960072-107257547)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia sh3rf31 SH3 domain containing ring finger 3 67.4(n)
    72.01(a)
      100490093  XM_002937660.2  XP_002937706.1 
    zebrafish
    (Danio rerio)
    Actinopterygii SH3RF36
    SH3 domain containing ring finger 3
    48(a)
    1 ↔ 1
    9(57554305-57606825) ENSDARG00000060401
    fruit fly
    (Drosophila melanogaster)
    Insecta POSH6
    Plenty of SH3s
    32(a)
    1 → many
    2R(13456232-13459827)
    worm
    (Caenorhabditis elegans)
    Secernentea sorb-16
    Protein SORB-1, isoform a (sorb-1) mRNA, complete ...
    12(a)
    1 → many
    IV(13750336-13770607) WBGene00012891


    ENSEMBL Gene Tree for SH3RF3 (if available)
    TreeFam Gene Tree for SH3RF3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for SH3RF3 gene
    SH3RF22  SORBS32  SORBS12  SH3RF12  SORBS22  SH3D192  
    15 SIMAP similar genes for SH3RF3 using alignment to 3 protein entries:     SH3R3_HUMAN (see all proteins):
    VAV1    GRAPL    SH3GL2    ABI2    NEB    ABI1
    ARHGEF7    ABI3    RAD18    SORBS3    SH3RF1    SH3GL1
    TRIM2    SH3RF2    ITSN2

    Find genes that share paralogs with SH3RF3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for SH3RF3 (see all 7924)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1885800211,2
    --109394127(+) GGCACC/TGTGGC 1 -- us2k10--------
    rs1141128271,2
    F--109394373(+) CTCTAG/TCCTGC 1 -- us2k11Minor allele frequency- T:0.03NA 120
    rs799921891,2
    C,F--109394380(+) CTGCCT/GGACAG 1 -- us2k11Minor allele frequency- G:0.02NA 120
    rs1927790101,2
    C--109394441(+) TTATCA/TGGCAG 1 -- us2k10--------
    rs1433538951,2
    --109394458(+) TTAGAA/GGATTA 1 -- us2k10--------
    rs1470861261,2
    C--109394463(+) GGATTA/GAATAA 1 -- us2k10--------
    rs1152468651,2
    C,F--109394497(+) TAGCCT/CCAACA 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1848570311,2
    --109394568(+) CAGGCC/TGGCCG 1 -- us2k10--------
    rs749814511,2
    C,F--109394612(+) GCCCTG/TACTGA 1 -- us2k11Minor allele frequency- T:0.04WA 118
    rs1883404001,2
    --109394643(+) CCAATC/GCTGGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SH3RF3 (109745804 - 109995804 bp, first 250kb of SH3RF3)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SH3RF3 (see all 20):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2720510CNV Deletion23290073
    esv2611227CNV Deletion19546169
    esv2720512CNV Deletion23290073
    esv2720511CNV Deletion23290073
    esv2720509CNV Deletion23290073
    esv2674570CNV Deletion23128226
    nsv508855CNV Insertion20534489
    nsv2873CNV Insertion18451855
    nsv508856CNV Insertion20534489
    nsv520698CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SH3RF3
    DNA2.0 Custom Variant and Variant Library Synthesis for SH3RF3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus

    Find genes that share disorders with SH3RF3           About GenesLikeMe

    Genetic Association Database (GAD): SH3RF3
    Human Genome Epidemiology (HuGE) Navigator: SH3RF3 (1 document)

    Export disorders for SH3RF3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SH3RF3 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with SH3RF3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome. (PubMed id 16374509)1, 2, 3 Kaerkkaeinen S.... Saksela K. (EMBO Rep. 2006)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    4. POSH2 is a RING finger E3 ligase with Rac1 binding activity through a partial CRIB domain. (PubMed id 20696164)1 KAorkkAoinen S....Renkema G.H. (FEBS Lett. 2010)
    5. Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (J. Proteome Res. 2008)
    6. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    8. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
    10. Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones. (PubMed id 12693554)2 Jikuya H....Ohara O. (DNA Res. 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 344558 HGNC: 24699 AceView: SH3MD4 Ensembl:ENSG00000172985 euGenes: HUgn344558
    ECgene: SH3RF3 H-InvDB: SH3RF3

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SH3RF3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SH3RF3 gene:
    Search GeneIP for patents involving SH3RF3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for SH3RF3   OriGene RNAi products in human, mouse, rat for SH3RF3  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for SH3RF3  
     OriGene MassSpec for SH3RF3   OriGene clones in human, mouse for SH3RF3  
     OriGene qSTAR qPCR primer pairs in human, mouse for SH3RF3   OriGene Purified Protein for SH3RF3  
     OriGene ORF clones in mouse, rat for SH3RF3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SH3RF3   OriGene Custom Protein Services for SH3RF3  

     
     
     Block miRNA regulation of human, mouse, rat SH3RF3 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SH3RF3
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SH3RF3 Predesigned siRNA for gene silencing in human, mouse, rat SH3RF3
     QuantiFast Probe-based Assays in human, mouse, rat SH3RF3 QuantiTect SYBR Green Assays in human, mouse, rat SH3RF3
     Custom PCR Arrays for SH3RF3 Search Chromatin IP Primers for SH3RF3
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SH3RF3  Search GeneGlobe Interaction Network for SH3RF3
     Regulatory tfbs in SH3RF3 promoter
     GenScript Custom Purified and Recombinant Proteins Services for SH3RF3 GenScript cDNA clones with any tag delivered in your preferred vector for SH3RF3
     GenScript Custom Assay Services for SH3RF3 GenScript Custom overexpressing Cell Line Services for SH3RF3
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SH3RF3 (SH3R3)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     SH3RF3 antibodies
     Antibodies for SH3RF3
     See all of Abcam's Antibodies, Kits and Proteins for SH3RF3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for SH3RF3
     Antibodies for SH3RF3
     ELISAs for SH3RF3
     CLIAs for SH3RF3



     Browse ESI BIO Cell Lines and PureStem Progenitors for SH3RF3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3RF3
     Browse SwitchGear 3'UTR luciferase reporter plasmids for SH3RF3
     Browse SwitchGear Promoter luciferase reporter plasmids for SH3RF3
     Search ThermoFisher Antibodies for SH3RF3
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SH3RF3
     Browse compounds at ApexBio
     Search Addgene for plasmids for SH3RF3
      Search eBioscience for proteins for SH3RF3
      Search eBioscience for elisas for SH3RF3
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for SH3RF3
     antibodies-online antibodies for SH3RF3 (13 products)
     antibodies-online kits for SH3RF3 (4 products)
     antibodies-online peptides for SH3RF3
      Search antibodies-online for proteins for SH3RF3
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SH3RF3 gene at Home site.
    Version: 3.12.258 10 Dec 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4