SH3RF1 Gene
protein-coding GIFtS : 56 GCID: GC04 M170015
SH3 domain containing ring finger 1 SH3 multiple domains 2 )SH3MD2 )
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Aliasesfor SH3RF1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases SH3 Domain Containing Ring Finger 1 1 2 SH3 Domain-Containing RING Finger Protein 12 3 POSH1 2 3 SH3 Multiple Domains Protein 22 3 RNF1421 2 3 E3 Ubiquitin-Protein Ligase SH3RF12 SH3MD21 2 3 Plenty Of SH3 Domains2 SH3 Multiple Domains 21 2 Putative E3 Ubiquitin-Protein Ligase SH3RF12 KIAA14941 3 EC 6.3.2.-3 Plenty Of SH3s2 3 Protein POSH3 RING Finger Protein 1422 3 EC 6.3.28
Export aliases for SH3RF1 gene to outside databases Previous GC identifers: GC04M170251 GC04M165769
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Summariesfor SH3RF1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for SH3RF1 : This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: SH3R1_HUMAN, Q7Z6J0 Function : Acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9)activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9) (By similarity). May be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane Function : Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specificE2 ubiquitin-conjugating enzymes such as UBE2D1 or UBE2N and then transfers it to substrates. In the absence of an external substrate, it can catalyze self-ubiquitination. Stimulates ubiquitination of potassium channel KCNJ1, enhancing it's dynamin-dependent and clathrin-independent endocytosis Function : Plays an essential role in the targeting of HIV-1 Gag to the plasma membrane, this function is dependent onit's RING domain, and hence it's E3 ligase activity Gene Wiki entry for SH3RF1
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Genomic Viewsfor SH3RF1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000004.11 NC_018915.1 NT_016354.19 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SH3RF1 gene promoter:TBP NF-1 NF-1/L AP-1 Egr-1 ATF-2 Egr-4 FOXJ2 (long isoform) c-Jun Other transcription factors Search SABiosciences Chromatin IP Primers for SH3RF1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 4q32.3 Ensembl cytogenetic band: 4q33 HGNC cytogenetic band: 4q32.3 SH3RF1 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 4 GeneLoc Exon Structure
GeneLoc location for GC04M170015: view genomic region
(about GC identifiers )
Start: 170,015,407 bp from pter End:
170,192,256 bp from pter
Size: 176,850 bases Orientation:
minus strand
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Proteinsfor SH3RF1 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: SH3R1_HUMAN, Q7Z6J0 See
protein sequence )Recommended Name: Size : 888 amino acids; 93129 DaSubunit : Interacts with Rac; in a GTP-dependent manner (By similarity). Interacts with MAP3K10 and MAP3K11. Interactswith MAPK8IP; this interaction leads to the PJAC complex (POSH-JIP or SH3RF1/MAPK8IP apoptotic complex) with a 1:1 ratio. Interacts with SIAH1. Interacts with HERP1. Probably part of a signaling complex that may contain SH3RF1, MAPK8IP, DLK1, MAP2K4, MAP2K7, MAPK8, MAPK9, AKT1 and AKT2
Subcellular location : Cytoplasm, perinuclear region (By similarity). Cell projection, lamellipodium. Cytoplasm. Golgiapparatus, trans-Golgi network. Note=Colocalizes, with AKT2, in lamellipodia (By similarity). Colocalizes, with HERP1, in trans-Golgi network
Sequence caution : Sequence=AAH33203.1; Type=Frameshift; Positions=182; Sequence=AAH33203.1; Type=Miscellaneousdiscrepancy; Note=Contaminating sequence. Potential poly-A sequence; Sequence=AAH53671.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the middle of the protein;
Secondary accessions : Q05BT2 Q8IW46 Q9HAM2 Q9P234Alternative splicing : 2 isoforms : Q7Z6J0-1 Q7Z6J0-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SH3RF1: NX_Q7Z6J0 Post-translational modifications:
Phosphorylated at Ser-304 by AKT1 and AKT2. When phosphorylated, it has reduced ability to bind Rac1 Subject to ubiquitination and proteasomal degradation (By similarity)1 View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q7Z6J0 4/19 DME Specific Peptides for SH3RF1 (Q7Z6J0 ) (see all 19 )SH3RF1 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_065921.2 ENSEMBL proteins: ENSP00000284637 ENSP00000426418 ENSP00000427585 ENSP00000421714 Human Recombinant Protein Products for SH3RF1: Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view) : About this table
About GeneDecksing SH3RF1 Antibody Products: Assay Products for SH3RF1:
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Protein
Domains /for SH3RF1 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 5 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q7Z6J0 ProtoNet protein and cluster: Q7Z6J0
1 Blocks protein family : IPB001841 UniProtKB/Swiss-Prot: SH3R1_HUMAN, Q7Z6J0 Domain : The RING finger domain is responsible of ubiquitination and proteasomal degradationSimilarity : Belongs to the SH3RF familySimilarity : Contains 1 RING-type zinc fingerSimilarity : Contains 4 SH3 domains
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Functionfor SH3RF1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: SH3R1_HUMAN, Q7Z6J0 Function : Acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9)activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9) (By similarity). May be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane Function : Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specificE2 ubiquitin-conjugating enzymes such as UBE2D1 or UBE2N and then transfers it to substrates. In the absence of an external substrate, it can catalyze self-ubiquitination. Stimulates ubiquitination of potassium channel KCNJ1, enhancing it's dynamin-dependent and clathrin-independent endocytosis Function : Plays an essential role in the targeting of HIV-1 Gag to the plasma membrane, this function is dependent onit's RING domain, and hence it's E3 ligase activity Enzyme Numbers (IUBMB): EC 6.3.2.- 1 EC 6.3.2 2
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view) : About this table
About GeneDecksing Animal Models: Clone Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 4 )human mouse rat see all 2 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: SH3RF1 (NM_020870 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SH3RF1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat SH3RF1
In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3RF1
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Pathways & Interactionsfor SH3RF1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways About this table See pathways by source Super-pathway contained gene-specific pathways 1 G13 Signaling Pathway
1 UniProtKB/Swiss-Prot: SH3R1_HUMAN, Q7Z6J0 Pathway : Protein modification; protein ubiquitinationInteractions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SH3RF1 STRING Interaction
Network Preview (showing 5 interactants - click image to see 20)5/22 Interacting proteins for SH3RF1 (Q7Z6J0 1 , 3 ENSP00000284637 4 via UniProtKB, MINT, STRING , and/or I2D (see all 22 )
About this table Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6 ): About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0006917 induction of apoptosis
IEA -- GO:0016567 protein ubiquitination
IEA -- GO:0043066 negative regulation of apoptotic process
IMP -- GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
IMP -- GO:0046328 regulation of JNK cascade
IEA --
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Drugs & Compoundsfor SH3RF1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for SH3RF1 1 HMDB Compound for SH3RF1 About this table SH3RF1 / SH3R1
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Transcriptsfor SH3RF1 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for SH3RF1 gene: NM_020870.3 Unigene Cluster for SH3RF1:
SH3 domain containing ring finger 1 Hs.301804 [show with all ESTs ] Unigene Representative Sequence: BC053671 5 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000284637 (uc003isa.1 ) ENST00000511421 ENST00000508685 (uc010irc.1 )ENST00000502315 ENST00000510806 Clone OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 4 )human mouse rat see all 2 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: SH3RF1 (NM_020870 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SH3RF1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat SH3RF1
Additional cDNA sequence: AB040927.1 AK021429.1 AK025255.1 AK026726.1 BC033203.1 BC041023.1 BC053671.1
7 DOTS entries : DT.308292 DT.100748160
DT.100009539 DT.101978498 DT.75138116 DT.75195914 DT.91995916 24/106 AceView cDNA sequences (see all 106 ):
AL601555 CN478827 BC033203 Z45709 NM_020870 BX093287 BI224417 BM722487 AB040927 AA742642 BC041023 CD672041 BG166931 BI223903 BX506138 N46563 BM836830 AK025255 CD672040 BE856667 BI962826 BF108450 BI962960 AA648838 GeneLoc Exon Structure 5/7 Alternative Splicing Database (ASD) splice patterns (SP) for SH3RF1 (see all 7 ) About this scheme ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b · 14c ^ 15 SP1 : - - - SP2 : - SP3 : SP4 : SP5 :
ECgene alternative splicing isoforms for SH3RF1
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Expression for SH3RF1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section SH3RF1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TTAATAATTTAbout this image SH3RF1 expression in embryonic tissues and stem cells About this table
See SH3RF1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SH3RF1 SOURCE GeneReport for Unigene cluster: Hs.301804 SABiosciences Custom PCR Arrays for SH3RF1 Primer OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3RF1
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Orthologsfor SH3RF1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for SH3RF1 gene from 5/18 species (see all 18 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
chicken Aves SH3RF11
SH3 domain containing ring finger 1
76.19(n) 80.5(a)
422434 XM_420402.3 XP_420402.2
lizard Reptilia SH3RF16
--
76(a)
1 ↔ 1
GL343216.1(587771-631323)
African clawed frog Amphibia BI449829.12
--
74.32(n)
BI449829.1
zebrafish Actinopterygii sh3rf11
SH3 domain containing ring finger 1
63.62(n) 66.82(a)
556523 NM_001045487.2 NP_001038952.2
fruit fly Insecta POSH6
Plenty of SH3s
27(a)
1 → many
2R(13456232-13459827)
ENSEMBL Gene Tree for SH3RF1 (if available)TreeFam Gene Tree for SH3RF1 (if available)
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Paralogsfor SH3RF1 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for SH3RF1 gene SH3RF3 2 SH3RF2 2 SORBS3 2 SORBS1 2 SORBS2 2 SH3D19 2 18 SIMAP similar genes for SH3RF1 using alignment to 4 protein entries: SH3R1_HUMAN (see all proteins ):SH3GL2 SH3GL1 GRAPL ARHGEF7 BRCA1 SH3RF3 RNF138 TRIM3 TRIM2 TRIM73 ITSN2 RFWD2 RNF152 TRIM59 RNF135 SH3RF2 BFAR TRIM5 About GeneDecksing
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Genomic Variantsfor SH3RF1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 4 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for SH3RF1 (170015407 - 170192256 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for SH3RF1 1 Indel 46554
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor SH3RF1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing 3 : About MalaCards benign paroxysmal positional nystagmus nystagmus hiv type 1 1 disease from the University of Copenhagen DISEASES database for SH3RF1 :Benign paroxysmal positional nystagmus Human Genome Epidemiology (HuGE) Navigator: SH3RF1 (1 document)Export disorders for SH3RF1 gene to outside databases
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Publicationsfor SH3RF1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for SH3RF1 gene, integrated from 9 sources (see all 27 ):(articles sorted by number of sources associating them with SH3RF1) Utopia : connect your pdf to the dynamic
Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex. (PubMed id 14504284) 1 , 2 , 9(2003) POSH stimulates the ubiquitination and the clathrin-i ndependent endocytosis of ROMK1 channels. (PubMed id 19710010) 1 , 2 (2009) Regulation of the pro-apoptotic scaffolding protein POSH by Akt. (PubMed id 17535800) 1 , 2 (2007) Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis. (PubMed id 16230351) 1 , 2 (2006) The trans-Golgi network-associated human ubiquitin-protein ligase POSH is essential for HIV type 1 production. (PubMed id 15659549) 1 , 2 (2005) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 (2004) Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331) 1 , 2 (2000) A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways. (PubMed id 9482736) 1 , 3(1998) Sh3rf2/POSHER protein promotes cell survival by ring-m ediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Pl enty of SH3s) protein. (PubMed id 22128169) 1 (2012) Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH. (PubMed id 21586138) 1 (2011)
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External Searches for SH3RF1 gene
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OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing SH3RF1 gene
(According to
Entrez Gene ,
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Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
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Specialized Databases showing SH3RF1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for SH3RF1 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for SH3RF1 gene: SH3RF1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor SH3RF1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for SH3RF1 OriGene 29mer shRNA kits in GFP-retroviral vector in human mouse rat OriGene genome-wide validated SYBR primer pairs in human mouse rat OriGene Protein Over-expression Lysate for SH3RF1 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for SH3RF1 OriGene 3'-UTR Clone for SH3RF1 OriGene untagged cDNA clones in CMV expression vector in human mouse rat OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for SH3RF1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for SH3RF1 OriGene Custom Protein Services for SH3RF1 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SH3RF1 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
Search Tocris compounds for SH3RF1
SH3RF1 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3RF1
Search ThermoFisher Antibodies for SH3RF1
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat SH3RF1
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Browse Tocris compounds for 
Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine 
Anatomical Compartment 
Negative
Selective marker
Curated
In-situ hybridization
