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SH3GLB2 Gene

protein-coding   GIFtS: 63
GCID: GC09M131769

SH3-Domain GRB2-Like Endophilin B2

(Previous names: SH3-domain, GRB2-like, endophilin B2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
SH3-Domain GRB2-Like Endophilin B21 2     RRIG12
SH3 Domain-Containing GRB2-Like Protein B22 3     endophilin-B22
SH3-Domain, GRB2-Like, Endophilin B21     Retinoid Receptor-Induced Gene 12
PP65692     SH3-Containing Protein SH3GLB22
PP94552     KIAA18483

External Ids:    HGNC: 108341   Entrez Gene: 569042   Ensembl: ENSG000001483417   OMIM: 6092885   UniProtKB: Q9NR463   
ORGUL members:         

Export aliases for SH3GLB2 gene to outside databases

Previous GC identifers: GC09M122884 GC09M123416 GC09M125223 GC09M127146 GC09M128849 GC09M130810 GC09M101377


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SH3GLB2 Gene:
SH3GLB2 (SH3-domain GRB2-like endophilin B2) is a protein-coding gene. Diseases associated with SH3GLB2 include prostate adenocarcinoma, and adenocarcinoma. An important paralog of this gene is SH3GL3.

Gene Wiki entry for SH3GLB2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NT_008470.20  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SH3GLB2 gene promoter:
         NF-1   AML1a   p53   Sp1   FOXF2   MIF-1   GATA-2   c-Ets-1   Evi-1   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SH3GLB2 promoter sequence
   Search Chromatin IP Primers for SH3GLB2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SH3GLB2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34   Ensembl cytogenetic band:  9q34.11   HGNC cytogenetic band: 9q34

SH3GLB2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SH3GLB2 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M131769:  view genomic region     (about GC identifiers)

Start:
131,769,315 bp from pter      End:
131,790,582 bp from pter
Size:
21,268 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SHLB2_HUMAN, Q9NR46 (See protein sequence)
Recommended Name: Endophilin-B2  
Size: 395 amino acids; 43974 Da
Subunit: Homodimer, and heterodimer with SH3GLB1
Sequence caution: Sequence=AAG23792.1; Type=Frameshift; Positions=122, 128; Sequence=BAB47477.2; Type=Erroneous
initiation;
Secondary accessions: A6NC47 A8MPS4 Q8WY61 Q96JH9
Alternative splicing: 2 isoforms:  Q9NR46-1   Q9NR46-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SH3GLB2: NX_Q9NR46

Explore proteomics data for SH3GLB2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys26, Lys276
  • Modification sites at PhosphoSitePlus

  • See SH3GLB2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001273974.1  NP_001273975.1  NP_064530.1  

    ENSEMBL proteins: 
     ENSP00000361645   ENSP00000361640   ENSP00000361634   ENSP00000402566   ENSP00000388282  
     ENSP00000396761   ENSP00000403228   ENSP00000400951  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR027267 AH/BAR-dom
     IPR001452 SH3_domain
     IPR004148 BAR_dom
     IPR028500 SH3GLB2

    Graphical View of Domain Structure for InterPro Entry Q9NR46

    ProtoNet protein and cluster: Q9NR46

    1 Blocks protein domain: IPB001452 SH3 domain signature

    UniProtKB/Swiss-Prot: SHLB2_HUMAN, Q9NR46
    Similarity: Belongs to the endophilin family
    Similarity: Contains 1 BAR domain
    Similarity: Contains 1 SH3 domain


    SH3GLB2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI11161816
         
    SH3GLB2 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for SH3GLB2:
     Decreased viability with pacli  Downregulation of NF-kappaB pa  Downregulation of NF-kappaB pa  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SH3GLB2
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    miRNA
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    miRTarBase miRNAs that target SH3GLB2:
    hsa-mir-17-5p (MIRT050894)

    Block miRNA regulation of human, mouse, rat SH3GLB2 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate SH3GLB2:
    hsa-miR-548t hsa-miR-182 hsa-miR-298 hsa-miR-1207-5p hsa-miR-3174 hsa-miR-1976
    SwitchGear 3'UTR luciferase reporter plasmidSH3GLB2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SH3GLB2

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    Sino Biological Human cDNA Clone for SH3GLB2
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SH3GLB2

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3GLB2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SHLB2_HUMAN, Q9NR46: Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol3

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005737cytoplasm IDA11161816

    SH3GLB2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SH3GLB2 About    
    See pathways by source

    SuperPathContained pathways About
    1Endocytosis
    Endocytosis

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1 Kegg Pathway  (Kegg details for SH3GLB2):
        Endocytosis


    SH3GLB2 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SH3GLB2
    Interactions:

        Search GeneGlobe Interaction Network for SH3GLB2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for SH3GLB2 (Q9NR461, 2, 3 ENSP000003616404) via UniProtKB, MINT, STRING, and/or I2D (see all 477)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SH3GLB2 (SHLB2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SH3GLB2 gene (3 alternative transcripts): 
    NM_001287045.1  NM_001287046.1  NM_020145.3  

    Unigene Cluster for SH3GLB2:

    SH3-domain GRB2-like endophilin B2
    Hs.460238  [show with all ESTs]
    Unigene Representative Sequence: AL832592
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372564(uc004bwv.3) ENST00000479237(uc022bon.1) ENST00000372559
    ENST00000372554(uc004bww.3) ENST00000461811 ENST00000417224 ENST00000416629
    ENST00000455407 ENST00000483980 ENST00000477165 ENST00000425236 ENST00000416230

    miRNA
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    6 qRT-PCR Assays for microRNAs that regulate SH3GLB2:
    hsa-miR-548t hsa-miR-182 hsa-miR-298 hsa-miR-1207-5p hsa-miR-3174 hsa-miR-1976
    SwitchGear 3'UTR luciferase reporter plasmidSH3GLB2 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: SH3GLB2 (NM_020145)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SH3GLB2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SH3GLB2
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    OriGene qPCR primer pairs and template standards for SH3GLB2
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SH3GLB2
      QuantiTect SYBR Green Assays in human, mouse, rat SH3GLB2
      QuantiFast Probe-based Assays in human, mouse, rat SH3GLB2

    Additional mRNA sequence: 

    AB058751.2 AF257319.1 AF258589.1 AF370426.1 AF370433.1 AL832592.1 BC005843.2 BC008029.1 
    BC014635.1 BC109236.1 

    Selected DOTS entries (see all 45):

    DT.95286005  DT.95367701  DT.100866699  DT.85104983  DT.100866700  DT.95367702  DT.100866693  DT.100832746 
    DT.95312072  DT.100866703  DT.86839407  DT.121164389  DT.91760229  DT.121164393  DT.121164539  DT.100866683 
    DT.85104198  DT.97855731  DT.100866678  DT.100866692  DT.100757041  DT.100866689  DT.95367698  DT.100840939 

    Selected AceView cDNA sequences (see all 656):

    BX381668 AI190406 BC005843 BF725118 AW593878 BX334586 BM976094 BC008029 
    AI680208 BM756247 AI597905 BM741916 BM756700 BX397295 BQ722172 AI568295 
    BQ067661 AI826281 AI042090 AI685955 AF370433 BE675626 BM756801 AI079941 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SH3GLB2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12
    SP1:                                      -                             -                           
    SP2:        -     -                       -                             -                           
    SP3:                                                                    -                           
    SP4:                                                                    -                           
    SP5:                                                                                                


    ECgene alternative splicing isoforms for SH3GLB2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SH3GLB2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACCCTGACT
    SH3GLB2 Expression
    About this image


    SH3GLB2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 12) fully expand
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Uterus (Reproductive System)
     
     Thyroid (Endocrine System)
     
     Lung (Respiratory System)
    SH3GLB2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SH3GLB2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.460238

    UniProtKB/Swiss-Prot: SHLB2_HUMAN, Q9NR46
    Tissue specificity: Detected in skeletal muscle, adipocyte, brain, lung, colon and mammary gland

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3GLB2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SH3GLB2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sh3glb21 , 5 SH3-domain GRB2-like endophilin B21, 5 90.38(n)1
    96.71(a)1
      2 (21.60 cM)5
    2277001  NM_139302.11  NP_647463.11 
     303448095 
    chicken
    (Gallus gallus)
    Aves SH3GLB21 SH3-domain GRB2-like endophilin B2 77.55(n)
    83.04(a)
      417197  NM_001006200.1  NP_001006200.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    25(a)
    many ↔ many
    AAWZ02039932(604-807)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.123632 Xenopus laevis transcribed sequence with moderate similarity more 79.22(n)    CD326079.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc558872 similar to SH3-domain GRB2-like endophilin B2 75.97(n)   394094  BC047195.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta endoB3 membrane organization and biogenesis 38(a)   56C10   --
    worm
    (Caenorhabditis elegans)
    Secernentea F35A5.8b3
    erp-11
    erp-11 49(a)
    (best of 2)3
    53.54(n)1
    49.04(a)1
      X(3836480-3838046)3
    1806671  NM_171657.41  NP_741756.11 


    ENSEMBL Gene Tree for SH3GLB2 (if available)
    TreeFam Gene Tree for SH3GLB2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SH3GLB2 gene
    SH3GL32  SH3GL12  SH3GLB12  SH3GL22  
    1 SIMAP similar gene for SH3GLB2 using alignment to 6 protein entries:     SHLB2_HUMAN (see all proteins):
    SH3GLB1

    SH3GLB2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SH3GLB2 (see all 537)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1860935111,2
    --131782975(+) TGAAAC/TGCCCG 1 -- int10--------
    rs1888752321,2
    --131783001(+) TGACCA/GCTACC 1 -- int10--------
    rs1813007441,2
    --131783038(+) CAGACA/GCATTC 1 -- int10--------
    rs174525411,2
    C,F,H--131783059(+) TCCACA/GATCCA 1 -- int15Minor allele frequency- G:0.03NS EA 538
    rs174330311,2
    C,H--131783099(+) ACGTTC/TCTTGT 1 -- int14Minor allele frequency- T:0.00NS EA 418
    rs1493839731,2
    --131783197(+) GAGCTC/GGGGGC 1 -- int10--------
    rs1474788141,2
    --131783204(+) GGGCCA/GGGGCA 1 -- int10--------
    rs283655381,2
    C,F--131783214(+) AGCCAC/TAGGGC 1 -- int11Minor allele frequency- T:0.10EA 120
    rs175081671,2
    C,F,H--131783243(+) AGAGTG/TGGGCA 1 -- int16Minor allele frequency- T:0.03NS EA CSA WA 538
    rs1399128281,2
    C--131783314(+) TGACTC/TGCACA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SH3GLB2 (131769315 - 131790582 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for SH3GLB2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2030052CNV Deletion18987734
    esv2568076CNV Deletion19546169
    nsv509323CNV Insertion20534489
    dgv8297n71CNV Loss21882294
    nsv831729CNV Loss17160897
    nsv818725CNV Gain17921354
    nsv893902CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609288    OMIM disorders: --

    4 diseases for SH3GLB2:    
    About MalaCards
    prostate adenocarcinoma    adenocarcinoma    prostatitis    breast cancer


    SH3GLB2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SH3GLB2
    Human Genome Epidemiology (HuGE) Navigator: SH3GLB2 (1 document)

    Export disorders for SH3GLB2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SH3GLB2 gene, integrated from 10 sources (see all 28):
    (articles sorted by number of sources associating them with SH3GLB2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. SH3GLB, a new endophilin-related protein family featuring an SH3 domain. (PubMed id 11161816)1, 2, 3, 9 Pierrat B.... Heim J. (Genomics 2001)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    4. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2 Nagase T.... Ohara O. (DNA Res. 2001)
    7. The Bin/amphiphysin/Rvs (BAR) domain protein endophilin B2 interacts with plectin and controls perinuclear cytoskeletal architecture. (PubMed id 23921385)1 Vannier C....Schmidt A.A. (J. Biol. Chem. 2013)
    8. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    9. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 56904 HGNC: 10834 AceView: SH3GLB2 Ensembl:ENSG00000148341 euGenes: HUgn56904
    ECgene: SH3GLB2 Kegg: 56904 H-InvDB: SH3GLB2

    (According to HUGE)
    About This Section

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    HUGE: KIAA1848

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SH3GLB2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for SH3GLB2 gene:
    Search GeneIP for patents involving SH3GLB2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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