SH3GLB1 Gene
protein-coding GIFtS: 63
GCID: GC01P087170
|
|
SH3-domain GRB2-like endophilin B1(Previous names: SH3-domain, GRB2-like, endophilin B1 )
| |
Aliases
for SH3GLB1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SH3-Domain GRB2-Like Endophilin B11 2 | | CGI-611 | | Bif-11 2 3 | | SH3-Domain, GRB2-Like, Endophilin B11 | | PPP1R701 2 | | DJ612B15.21 | | KIAA04911 3 | | Endophilin-B11 | | Bax-Interacting Factor 12 3 | | Protein Phosphatase 1, Regulatory Subunit 702 | | SH3 Domain-Containing GRB2-Like Protein B12 3 | | SH3-Containing Protein SH3GLB12 |
Export aliases for SH3GLB1 gene to outside databasesPrevious GC identifers: GC01P087672 GC01P086339 GC01P086462 GC01P086593 GC01P086882 GC01P085280 |
Summaries
for SH3GLB1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SH3GLB1:
This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptoticmember of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signalingpathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results inmultiple transcript variants. (provided by RefSeq, Sep 2011)
UniProtKB/Swiss-Prot: SHLB1_HUMAN, Q9Y371Function: May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrogradetransport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion
Gene Wiki entry for SH3GLB1
|
Genomic Views
for SH3GLB1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SH3GLB1 gene promoter:
Sox5 FOXO3 Cdc5 NF-kappaB Ik-3 FOXO3b HFH-1 NF-kappaB2 FOXO3a NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SH3GLB1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SH3GLB1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p22 Ensembl cytogenetic band: 1p22.3 HGNC cytogenetic band: 1p22.3SH3GLB1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P087170: view genomic region
(about GC identifiers)
Start:
|
87,170,257 bp from pter |
End:
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87,213,867 bp from pter |
Size:
|
43,611 bases |
Orientation:
|
plus strand |
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Proteins
for SH3GLB1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SHLB1_HUMAN, Q9Y371 (See
protein sequence)Recommended Name: Endophilin-B1 Size: 365 amino acids; 40796 Da
Subunit: Binds DNM1, HTT, AMPH, BIN1 and ARFGAP1 (By similarity). Homodimer, and heterodimer with SH3GLB2. Binds BAX.Induction of apoptosis augments BAX binding
Subcellular location: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein (By similarity). Mitochondrionouter membrane; Peripheral membrane protein. Note=Association with the Golgi apparatus depends on the cell type (Bysimilarity)
Miscellaneous: HeLa cells lacking SH3GLB1 show dissociation of outer and inner mitochondrial membrane as well asabnormal mitochondrial morphology. Cells overexpressing SH3GLB1 lacking an N-terminal amphipathic helix show a similarphenotype
Miscellaneous: SH3GLB1 binds liposomes and induces formation of tubules from liposomes. SH3GLB1 lacking the N-terminalamphipathic helix fails to induce liposome tubulation
Caution: It is uncertain whether Met-1 or Met-4 is the initiator
Caution: Was originally (PubMed:12456676) thought to have lysophosphatidic acid acyltransferase activity, but byhomology with SH3GL2/endophilin A1 is unlikely to have this activity
Sequence caution: Sequence=AAF81225.1; Type=Erroneous initiation; Sequence=BAD88797.1; Type=Erroneous initiation;
Secondary accessions: B4E182 Q5H8U5 Q9H3Z0 Q9NR47 Q9NYA9Alternative splicing: 3 isoforms: Q9Y371-1 Q9Y371-2 Q9Y371-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SH3GLB1: NX_Q9Y371
Post-translational modifications:
Phosphorylated at Thr-145 by CDK5; this phosphorylation is required for autophagy induction in starved neurons andfacilitates homodimerization1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y371
SH3GLB1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001193580.1 NP_001193581.1 NP_001193582.1 NP_057093.1
ENSEMBL proteins: ENSP00000212369 ENSP00000418744 ENSP00000441355
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
SH3GLB1 for ontologies About GeneDecksing
SH3GLB1 Antibody Products:
Assay Products for SH3GLB1: |
Protein
Domains /
Families
for SH3GLB1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SH3GLB1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y371ProtoNet protein and cluster: Q9Y371 1 Blocks protein family: IPB001452 SH3 domain signature
UniProtKB/Swiss-Prot: SHLB1_HUMAN, Q9Y371Domain: An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BARdomain (N-BAR domain) induce membrane curvature and bind curved membranesSimilarity: Belongs to the endophilin familySimilarity: Contains 1 BAR domainSimilarity: Contains 1 SH3 domain |
Function
for SH3GLB1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SHLB1_HUMAN, Q9Y371Function: May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrogradetransport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SH3GLB1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SH3GLB1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): SH3GLB1 (NM_016009) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SH3GLB1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SH3GLB1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3GLB1 |
Gene Ontology (GO): 5/9 molecular function terms (GO ID links to tree view) (see all 9): About this table
SH3GLB1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SH3GLB1:
Animal Models:
Mouse knock-out Sh3glb1tm1Hgw for SH3GLB1
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Sh3glb1):
SH3GLB1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SH3GLB1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Clathrin-dependent protein traffic | | | 2 | Apoptosis and Autophagy | | | 3 | Senescence and Autophagy | | | 4 | Endocytosis | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for SH3GLB1
2  GeneGo (Thomson Reuters) Pathways for SH3GLB1
1  BioSystems Pathway for SH3GLB1
1 
Kegg Pathway (Kegg details for SH3GLB1):
SH3GLB1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SH3GLB1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/236 Interacting proteins for SH3GLB1 (Q9Y3711, 2, 3 ENSP000002123694) via UniProtKB, MINT, STRING, and/or I2D (see all 236)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| BAX | Q078121, 3, ENSP000002932884 | EBI-5291808,EBI-516580 I2D:
score=2 STRING: ENSP00000293288 | | ADAM15 | Q134442, 3, ENSP000003494364 | MINT-2792541 I2D:
score=1 STRING: ENSP00000349436 | | UVRAG | Q9P2Y52, 3, ENSP000003484554 | MINT-7235295 MINT-7235266 I2D:
score=2 STRING: ENSP00000348455 | | SH3GLB2 | Q9NR461, 3, ENSP000003616404 | EBI-2623095,EBI-749607 I2D:
score=6 STRING: ENSP00000361640 | | HTT | P428583, ENSP000003471844 | I2D:
score=4 STRING: ENSP00000347184 |
About this table
Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001844 | protein insertion into mitochondrial membrane involved in apoptotic signaling pathway |
-- | -- | | GO:0006654 | phosphatidic acid biosynthetic process |
IEA | -- | | GO:0006915 | apoptotic process |
IEA | -- | | GO:0007165 | signal transduction |
-- | -- | | GO:0008654 | phospholipid biosynthetic process |
-- | -- |
SH3GLB1 for ontologies About GeneDecksing
|
Drugs & Compounds
for SH3GLB1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SH3GLB1
Search CenterWatch for drugs/clinical trials and news about SH3GLB1 / SHLB1
|
Transcripts
for SH3GLB1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SH3GLB1 gene (4 alternative transcripts): NM_001206651.1 NM_001206652.1 NM_001206653.1 NM_016009.4 Unigene Cluster for SH3GLB1: SH3-domain GRB2-like endophilin B1 Hs.136309 [show with all ESTs]Unigene Representative Sequence: NM_0012066514 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000212369 ENST00000482504 ENST00000370558(uc001dlx.3 uc001dly.3 uc001dlw.3 uc001dlz.3)
ENST00000535010
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SH3GLB1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SH3GLB1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): SH3GLB1 (NM_016009) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SH3GLB1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SH3GLB1 |
Additional cDNA sequence: AB007960.2 AF151819.1 AF257318.1 AF263293.1 AF350371.1 AK001954.1 AK225864.1 AK303710.1 BC007455.2 10 DOTS entries: DT.444330 DT.100812769 DT.100812771 DT.100812772 DT.121410516 DT.115561 DT.121410541 DT.95315781 DT.95315787 DT.115564 24/379 AceView cDNA sequences (see all 379): CA407823 BM998603 AK001954 AA574177 N49038 AI190529 AI383627 AL543329 BG621400 AF263293 AA810592 AV648539 AV713795 AA253124 BU674912 BI826056 BC007455 AI341196 AI142631 AL599954 AI476281 CA772392 AI224003 CD724259
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for SH3GLB1 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SH3GLB1
|
Expression
for SH3GLB1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SH3GLB1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATATTCCATC
About this image
See SH3GLB1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SH3GLB1
SOURCE GeneReport for Unigene cluster: Hs.136309
UniProtKB/Swiss-Prot: SHLB1_HUMAN, Q9Y371Tissue specificity: Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain,colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes
SABiosciences Expression via Pathway-Focused PCR Arrays including SH3GLB1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SH3GLB1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SH3GLB1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SH3GLB1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SH3GLB1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3GLB1 |
Orthologs
for SH3GLB1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SH3GLB1 gene from 6/24 species (see all 24) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SH3GLB11 |
SH3-domain GRB2-like endophilin B1 |
82.64(n)
89.47(a) |
|
424522 NM_001006534.1 NP_001006534.1 |
lizard
(Anolis carolinensis) |
Reptilia |
SH3GLB16 |
-- |
85(a) |
1 ↔ 1 |
4(97400581-97428463) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.258262 |
Xenopus laevis transcribed sequence with weak similarity more |
78.57(n) |
|
BU913782.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufa08f032 |
Danio rerio, clone IMAGE5777505, mRNA |
76.16(n) |
|
BC050954.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
endoB1 , 3 |
membrane organization and biogenesis3
endophilin B1 |
39(a)3
49.6(n)1
43.16(a)1 |
|
56C103
372181 NM_137566.31 NP_611410.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
F35A5.8b3 |
-- |
51(a)
(best of 2) |
|
X(3836480-3838046) -- |
ENSEMBL Gene Tree for SH3GLB1 (if available)
TreeFam Gene Tree for SH3GLB1 (if available) |
Paralogs
for SH3GLB1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SH3GLB1 gene
- SH3GL32 SH3GL12 SH3GL22 SH3GLB22
1 SIMAP similar gene for SH3GLB1 using alignment to 1 protein entry: SHLB1_HUMAN:SH3GLB2
SH3GLB1 for paralogs About GeneDecksing
|
Genomic Variants
for SH3GLB1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SH3GLB1 (87170257 - 87213867 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SH3GLB1
2 CNVs: 84353 74560 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for SH3GLB1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SH3GLB1 for disorders About GeneDecksing
OMIM gene information: 609287
OMIM disorders: --
11  diseases for SH3GLB1: About MalaCardsmerkel cell carcinoma pancreatic ductal adenocarcinoma gallbladder cancer parkinson's disease
adenocarcinoma prostate cancer pancreatitis prostatitis
carcinoma vesiculitis neuronitis
Human Genome Epidemiology (HuGE) Navigator: SH3GLB1 (1 document)
Export disorders for SH3GLB1 gene to outside databases
|
Publications
for SH3GLB1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SH3GLB1 gene, integrated from 9 sources (see all 53):
(articles sorted by number of sources associating them with SH3GLB1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- SH3GLB, a new endophilin-related protein family featuring an SH3 domain. (PubMed id 11161816)1, 2, 3, 9 Pierrat B.... Heim J. (2001)
- Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax. (PubMed id 11259440)1, 2, 3 Cuddeback S.M....Wang H.G. (2001)
- Endophilin B1 is required for the maintenance of mitochondrial morphology. (PubMed id 15452144)1, 2, 9 Karbowski M.... Youle R.J. (2004)
- Characterization of endophilin B1b, a brain-specific membrane- associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1. (PubMed id 12456676)1, 2, 9 Modregger J.... Plomann M. (2003)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.H....Lin W. (2000)
- Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. (PubMed id 9455484)1, 2 Seki N.... Ohara O. (1997)
- Decreased expression of Bax-interacting factor-1 (Bif-1) in invasive urinary bladder and gallbladder cancers. (PubMed id 18752120)1, 9 Kim S.Y....Lee S.H. (2008)
|
External Searches for SH3GLB1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SH3GLB1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SH3GLB1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SH3GLB1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SH3GLB1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SH3GLB1 gene:
Search GeneIP for patents involving SH3GLB1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SH3GLB1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for SH3GLB1 | | OriGene shRNA RFP for SH3GLB1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SH3GLB1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SH3GLB1 | | | OriGene Protein Over-expression Lysate for SH3GLB1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SH3GLB1 | | OriGene 3'-UTR Clone for SH3GLB1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SH3GLB1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SH3GLB1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SH3GLB1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SH3GLB1 | | OriGene Custom Protein Services for SH3GLB1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SH3GLB1 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SH3GLB1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SH3GLB1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SH3GLB1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SH3GLB1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SH3GLB1 |
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| | | | Search Tocris compounds for SH3GLB1 |
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 | | | SH3GLB1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3GLB1 |
|  |  |  | | | | ThermoFisher Antibodies for SH3GLB1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SH3GLB1 |
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