SH3GL1 Gene
protein-coding GIFtS: 61
GCID: GC19M004360
|
|
SH3-domain GRB2-like 1
| |
Aliases
for SH3GL1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SH3-Domain GRB2-Like 11 2 | | SH3 Domain-Containing GRB2-Like Protein 12 3 | | EEN1 2 3 5 | | MGC1113711 | | CNSA11 2 3 | | Endophilin-23 | | SH3D2B1 2 3 | | Endophilin-A21 | | SH3P81 2 | | Extra 11-19 Leukemia Fusion2 | | Extra Eleven-Nineteen Leukemia Fusion Gene Protein2 3 | | SH3-Containing Grb-2-Like 1 Protein2 | | EEN Fusion Partner Of MLL2 3 | | Endophilin-23 | | SH3 Domain Protein 2B2 3 | | |
Export aliases for SH3GL1 gene to outside databasesPrevious GC identifers: GC19M004452 GC19M004300 GC19M004311 GC19M004122 |
Summaries
for SH3GL1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SH3GL1:
This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded proteinis involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role inleukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of themyeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17.Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. (provided byRefSeq, Jan 2011)
UniProtKB/Swiss-Prot: SH3G1_HUMAN, Q99961Function: Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity)
Gene Wiki entry for SH3GL1
|
Genomic Views
for SH3GL1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011255.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SH3GL1 gene promoter:
AP-1 AML1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for SH3GL1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SH3GL1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3SH3GL1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M004360: view genomic region
(about GC identifiers)
Start:
|
4,360,367 bp from pter |
End:
|
4,400,522 bp from pter |
Size:
|
40,156 bases |
Orientation:
|
minus strand |
|
Proteins
for SH3GL1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SH3G1_HUMAN, Q99961 (See
protein sequence)Recommended Name: Endophilin-A2 Size: 368 amino acids; 41490 Da
Subunit: Interacts with ARC (By similarity). Interacts with SYNJ1 and DNM1. Interacts with PDCD6IP. Interacts with BIN2
Subcellular location: Cytoplasm (By similarity). Early endosome membrane; Peripheral membrane protein (By similarity).Cell projection, podosome. Note=Associated with postsynaptic endosomes in hippocampal neurons (By similarity)
Secondary accessions: B4DRA1 E7EVZ4 Q99668Alternative splicing: 2 isoforms: Q99961-1 Q99961-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SH3GL1: NX_Q99961
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q99961
SH3GL1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001186872.1 NP_001186873.1 NP_003016.1
ENSEMBL proteins: ENSP00000269886 ENSP00000404568
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IDA | -- | | GO:0031901 | early endosome membrane |
IEA | -- |
SH3GL1 for ontologies About GeneDecksing
SH3GL1 Antibody Products:
Assay Products for SH3GL1: |
Protein
Domains /
Families
for SH3GL1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SH3GL1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q99961ProtoNet protein and cluster: Q99961 1 Blocks protein family: IPB001452 SH3 domain signature
UniProtKB/Swiss-Prot: SH3G1_HUMAN, Q99961Domain: An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BARdomain (N-BAR domain) induce membrane curvature and bind curved membranes (By similarity)Similarity: Belongs to the endophilin familySimilarity: Contains 1 BAR domainSimilarity: Contains 1 SH3 domain |
Function
for SH3GL1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SH3G1_HUMAN, Q99961Function: Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity) Genatlas biochemistry entry for SH3GL1:Src-homology 3 domain GRB2-like gene 1,ubiquitously expressed
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SH3GL1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SH3GL1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): SH3GL1 (NM_003025) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SH3GL1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SH3GL1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3GL1 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
SH3GL1 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for SH3GL1:
|
Pathways & Interactions
for SH3GL1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Endocytosis | | | 2 | Signaling events mediated by focal adhesion kinase | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for SH3GL1
1 
Kegg Pathway (Kegg details for SH3GL1):
SH3GL1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SH3GL1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/64 Interacting proteins for SH3GL1 (Q999611, 2, 3 ENSP000002698864) via UniProtKB, MINT, STRING, and/or I2D (see all 64)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| DPPA4 | Q7L1901, 2, 3, ENSP000003353064 | EBI-697911,EBI-710457 MINT-8270330 I2D:
score=6 STRING: ENSP00000335306 | | SYNJ1 | O434262, 3, ENSP000003222344 | MINT-8096061 MINT-8096099 MINT-8096027 I2D:
score=3 STRING: ENSP00000322234 | | SH3KBP1 | Q96B972, 3, ENSP000003809214 | MINT-18019 MINT-18017 MINT-18018 I2D:
score=2 STRING: ENSP00000380921 | | SH2D4A | Q9H7881, 3, ENSP000002658074 | EBI-697911,EBI-2558037 I2D:
score=4 STRING: ENSP00000265807 | | DPYSL4 | O145312, 3, ENSP000003398504 | MINT-8270341 I2D:
score=2 STRING: ENSP00000339850 |
About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
SH3GL1 for ontologies About GeneDecksing
|
Drugs & Compounds
for SH3GL1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SH3GL1
Search CenterWatch for drugs/clinical trials and news about SH3GL1 / SH3G1
|
Transcripts
for SH3GL1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SH3GL1 gene (3 alternative transcripts): NM_001199943.1 NM_001199944.1 NM_003025.3 Unigene Cluster for SH3GL1: SH3-domain GRB2-like 1 Hs.97616 [show with all ESTs]Unigene Representative Sequence: NM_0030252 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000269886(uc002mak.3 uc002maj.3 uc010xig.2) ENST00000417295
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SH3GL1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SH3GL1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): SH3GL1 (NM_003025) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SH3GL1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SH3GL1 |
Additional cDNA sequence: AK097616.1 AK299166.1 AK315450.1 AY364240.1 BC000089.2 BC001094.2 BC001270.1 BC014387.2 BC098565.1 CR542087.1 U65999.1 X99656.1 15 DOTS entries: DT.454463 DT.100840804 DT.100832273 DT.121469726 DT.100038384 DT.100711751 DT.100825112 DT.100825122 DT.100825102 DT.100825117 DT.121469746 DT.92450437 DT.95368598 DT.97776717 DT.100825116 24/431 AceView cDNA sequences (see all 431): CD370859 F12558 BI767439 BM666763 AI357771 BQ058123 CD672585 BE779200 BM757269 BC014387 BC001270 CA388750 BU543229 BQ073774 BM772949 BX399000 AW300991 BX375014 BM802335 BF593747 AK097616 AA298027 CR622297 BG748247
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for SH3GL1 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 |
|---|
|
| SP1: | | | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SH3GL1
|
Expression
for SH3GL1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SH3GL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGGGCGCAG
About this image
See SH3GL1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SH3GL1
SOURCE GeneReport for Unigene cluster: Hs.97616
UniProtKB/Swiss-Prot: SH3G1_HUMAN, Q99961Tissue specificity: Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus
SABiosciences Custom PCR Arrays for SH3GL1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SH3GL1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SH3GL1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SH3GL1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SH3GL1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3GL1 |
Orthologs
for SH3GL1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SH3GL1 gene from 7/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Sh3gl11 , 5 |
SH3-domain GRB2-like 11, 5 |
88.04(n)1
94.02(a)1 |
|
17 (29.11 cM)5
204051 NM_013664.31 NP_038692.11
560167535 |
chicken
(Gallus gallus) |
Aves |
SH3GL11 |
SH3-domain GRB2-like 1 |
83.2(n)
91.55(a) |
|
395202 NM_204529.1 NP_989860.1 |
lizard
(Anolis carolinensis) |
Reptilia |
--SH3GL16 |
-- |
87(a)82(a) |
possible ortholog1 ↔ 1 |
AAWZ02039932(604-807) AAWZ02037346(4681-16523) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.41752 |
Xenopus laevis transcribed sequence with moderate similarity more |
74.66(n) |
|
BX847835.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.210432 |
Danio rerio mRNA similar to SH3-domain GRB2-like 1 more |
78.04(n) |
|
BC045942.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
endoA3 |
synaptic vesicle endocytosis
lysophosphatidic more |
48(a) |
|
91D4 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
T04D1.33
unc-571 |
Protein UNC-571 |
50(a)3
52.2(n)1
48.35(a)1 |
|
I(4675134-4676809)3
1720781 NM_001129041.11 NP_001122513.11 |
ENSEMBL Gene Tree for SH3GL1 (if available)
TreeFam Gene Tree for SH3GL1 (if available) |
Paralogs
for SH3GL1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SH3GL1 gene
- SH3GL32 SH3GLB12 SH3GL22 SH3GLB22
18/52 SIMAP similar genes for SH3GL1 using alignment to 8 protein entries: SH3G1_HUMAN (see all proteins)
(see all similar genes):SH3GL2 DKFZp686B23205 SH3GL3 ABI-2 ABI2 SGSM3
SNX18 SH3D19 SH3RF1 ARHGEF5 DKFZp686N08224 PACSIN1
SORBS1 GRB2 ABI1 SH3KBP1 ARHGEF6 HCLS1
SH3GL1 for paralogs About GeneDecksing
5 Pseudogenes.org Pseudogenes for SH3GL1
PGOHUM00000242897 PGOHUM00000237166 PGOHUM00000237347 PGOHUM00000237358 PGOHUM00000262602
|
Genomic Variants
for SH3GL1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SH3GL1 (4360367 - 4400522 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SH3GL1
1 CNV: 5075
Human Gene Mutation Database (HGMD): SH3GL1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SH3GL1 |
|
Disorders
/ Diseases
for SH3GL1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SH3GL1 for disorders About GeneDecksing
OMIM gene information: 601768
OMIM disorders: 601626
UniProtKB/Swiss-Prot: SH3G1_HUMAN, Q99961
Note=In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene
10  diseases for SH3GL1: About MalaCardsleukemia acute myeloid leukemia clear cell hidradenoma lymphoid leukemia
myeloid leukemia hidradenoma scoliosis prostatitis
neuronitis immunodeficiency
1 disease from the University of Copenhagen DISEASES database for SH3GL1:Leukemia 1 Novoseek disease relationship for SH3GL1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| leukemogenesis |
75.7 |
5 |
16990610 (2), 14551139 (1), 15077184 (1) |
Export disorders for SH3GL1 gene to outside databases
|
Publications
for SH3GL1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SH3GL1 gene, integrated from 9 sources (see all 43):
(articles sorted by number of sources associating them with SH3GL1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel SH3-containing human gene family preferentially expressed in the central nervous system. (PubMed id 9169142)1, 2, 3 Giachino C....Migone N. (1997)
- EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia. (PubMed id 9122235)1, 2, 9 So C.W.... Chan L.C. (1997)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The SH3 domains of endophilin and amphiphysin bind to the proline- rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity. (PubMed id 10542231)1, 2 Cestra G.... Cesareni G. (1999)
- Aberrant transcriptional regulation of the MLL fusion partner EEN by AML1-ETO and its implication in leukemogenesis. (PubMed id 16990610)1, 9 Ma L.H....Chen S.J. (2007)
- Functional contribution of EEN to leukemogenic transformation by MLL-EEN fusion protein. (PubMed id 15077184)1, 9 Liu H....Chen S.J. (2004)
- Activation of EGF receptor endocytosis and ERK1/2 signaling by BPGAP1 requires direct interaction with EEN/endophilin II and a functional RhoGAP domain. (PubMed id 15944398)1, 9 Lua B.L. and Low B.C. (2005)
- Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein. (PubMed id 14551139)1, 9 Yam J.W.... Chan L.C. (2004)
- LRRK2 controls an EndoA phosphorylation cycle in synap tic endocytosis. (PubMed id 22998870)1 Matta S....Verstreken P. (2012)
|
External Searches for SH3GL1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SH3GL1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SH3GL1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SH3GL1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for SH3GL1 gene:
Search GeneIP for patents involving SH3GL1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SH3GL1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for SH3GL1 | | OriGene shRNA RFP for SH3GL1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SH3GL1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SH3GL1 | | | OriGene Protein Over-expression Lysate for SH3GL1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SH3GL1 | | OriGene 3'-UTR Clone for SH3GL1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SH3GL1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SH3GL1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SH3GL1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SH3GL1 | | OriGene Custom Protein Services for SH3GL1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SH3GL1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SH3GL1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SH3GL1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SH3GL1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SH3GL1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SH3GL1 |
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| | | | Search Tocris compounds for SH3GL1 |
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 | | | SH3GL1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3GL1 |
|  |  |  | | | | ThermoFisher Antibody for SH3GL1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SH3GL1 |
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