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SH3GL1 Gene

protein-coding GIFtS: 63

GC19M004311

SH3-domain GRB2-like 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
CNSA1 ^¹, ², ³
EEN ^¹, ², ³, ⁵
Endophilin-2 ^³
MGC111371 ^¹, ²
SH3D2B ^¹, ², ³
SH3P8 ^¹, ²

Descriptions
EEN fusion partner of MLL ^³
Extra eleven-nineteen leukemia fusion gene protein ^³
SH3 domain GRB2-like 1 ^²
SH3 domain protein 2B ^³
SH3 domain-containing GRB2-like protein 1 ^³
SH3-containing Grb-2-like 1 protein ^²
SH3-containing protein EEN ^²
SH3-domain GRB2-like 1 ^²
extra 11-19 leukemia fusion ^²
fusion partner of MLL ^²

External Ids
HGNC: 10830¹
Entrez Gene: 6455²
UniProtKB: Q99961³
Ensembl: ENSG00000141985⁷

Search outside databases for aliases for SH3GL1 gene

Previous GC identifers: GC19M004452 GC19M004300

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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UniProtKB/Swiss-Prot: SH3G1_HUMAN, Q99961

Function: Implicated in endocytosis. May recruit other proteins to membranes with high curvature

(By similarity)

Gene Wiki entry for SH3GL1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the SH3GL1 gene

Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3

SH3GL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19M004311: (about GC identifiers)

Start:	4,311,367 bp from pter
End:	4,351,496 bp from pter
Size:	40,130 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000019.8 NT_011255.14

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: SH3G1_HUMAN, Q99961 (See protein sequence)

Recommended Name: Endophilin-A2

Size: 368 amino acids; 41490 Da

Subunit: Interacts with ARC (By similarity). Interacts with SYNJ1 and DNM1. Interacts with PDCD6IP

Subcellular location: Cytoplasm (By similarity). Early endosome membrane; Peripheral membrane

protein (By similarity). Note=Associated with postsynaptic endosomes in hippocampal neurons (By

similarity)

Secondary accessions: Q99668

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_003016.1

ENSEMBL proteins:

ENSP00000269886

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (pan Endophilin, SH3 containing Grb 2 like 1 protein)
	Human Recombinant Proteins from Abnova (SH3GL1)

OriGene Purified Recombinant Human Protein: SH3GL1

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005768	endosome	IEA	--
GO:0016020	membrane	IEA	--
GO:0031901	early endosome membrane	IEA	--

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Antibodies for SH3GL1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for SH3GL1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (pan Endophilin, SH3 containing Grb 2 like 1 protein), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (SH3GL1)
	Novus Biologicals Antibodies for SH3GL1

Assays for SH3GL1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q99961

ProtoNet protein and cluster: Q99961

1 Blocks protein family: IPB001452 SH3 domain signature

UniProtKB/Swiss-Prot: SH3G1_HUMAN, Q99961

Domain: An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted

into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes

(By similarity)

Similarity: Belongs to the endophilin family

Similarity: Contains 1 BAR domain

Similarity: Contains 1 SH3 domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SH3GL1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SH3GL1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003025

Applied Biosystems Silencer® siRNAs for SH3GL1

Sigma-Aldrich siRNA for SH3GL1

Sigma-Aldrich shRNA for SH3GL1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for SH3GL1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_003025
Myc/DDK tagged cDNA clone in CMV expression vector: NM_003025
untagged cDNA clones in CMV expression vector (see all 3): NM_003025

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_003025

UniProtKB/Swiss-Prot: SH3G1_HUMAN, Q99961

Function: Implicated in endocytosis. May recruit other proteins to membranes with high curvature

Src-homology 3 domain GRB2-like gene 1,ubiquitously expressed

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	16169070
GO:0008289	lipid binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Gene Network Central^TM Interacting Genes and Proteins Network for SH3GL1

5/10 Interacting proteins for SH3GL1 (Q99961^{1, 2} ENSP00000269886³) via UniProtKB, MINT, and/or STRING (see all 10 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SH3KBP1	Q96B97², ENSP00000369049³	MINT-18019 MINT-18017 MINT-18018 STRING (score=.88)
DPPA4	Q7L190¹	EBI-697911, EBI-710457
PDCD6IP	ENSP00000307387³	STRING (score=.969)
PRR5	ENSP00000337560³	STRING (score=.966)
DNM1	ENSP00000362014³	STRING (score=.961)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006897	endocytosis	IEA	--
GO:0007165	signal transduction	TAS	9169142
GO:0007417	central nervous system development	TAS	9169142

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for SH3GL1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SH3GL1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SH3GL1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003025

Sigma-Aldrich siRNA for SH3GL1

Sigma-Aldrich shRNA for SH3GL1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_003025

REFSEQ mRNAs for SH3GL1 gene:

NM_003025.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_003025

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_003025
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_003025
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_003025

Additional cDNA sequence:

AK097616.1 AK299166.1 AK315450.1 AY364240.1 BC000089.2 BC001094.2 BC001270.1 BC014387.2

BC098565.1 CR542087.1 CR591966.1 CR592875.1 CR593755.1 CR597141.1 CR602738.1 CR613203.1

CR618121.1 CR622297.1 U65999.1 X99656.1

15 DOTS entries:

DT.454463 DT.100840804 DT.100832273 DT.121469726 DT.100038384 DT.100711751 DT.100825112 DT.100825122

DT.100825102 DT.100825116 DT.100825117 DT.121469746 DT.92450437 DT.95368598 DT.97776717

24/431 AceView cDNA sequences (see all 431 ):

BQ927755 BQ058123 NM_003025 BQ954686 CR593755 BQ232981 AI357771 BG030676

BQ068252 BG748247 CR602738 CR622297 AU125067 AW591078 BQ642070 BU628211

BC014387 BM678851 BX339719 AA296899 BM802335 BQ070669 BU508518 CR592875

highest scoring ESTs for SH3GL1:

X99656 AK097616 AL529468 BC001270 BE300361 BI752462 BI767439 BI824373 BQ070669 BQ695166

Unigene Cluster for SH3GL1:

SH3-domain GRB2-like 1

Hs.97616 [show with all ESTs]

Unigene Representative Sequence: BC098565

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for SH3GL1

ExUns:	1	^	2	^	3	^	4a	·	4b	^	5a	·	5b	^	6	^	7	^	8	^	9	^	10
SP1:									-		-
SP2:

About this scheme

ECgene alternative splicing isoforms for SH3GL1

1 Ensembl transcript including schematic representation:

ENST00000269886

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

SH3GL1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for SH3GL1

¹ / ² / ³

3 probe-sets matching SH3GL1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
39159_at²^{, 3}	U95-A	2	1.00	0.91	1.00	1.00	X99656	1.00	1.00	1.00	1
201851_at²^{, 3}	U133-A	2	1.00	0.91	--	--	NM_003025	0.60	1.00	0.82	1
201851_at²	U133Plus2	2	1.00	0.91	--	--	--	--	--	--	--

GeneDecks SH3GL1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AGGGGCGCAG

SOURCE GeneReport for Unigene cluster: Hs.97616
Expression variation in blood from EXPOLDB for SH3GL1
UniProtKB/Swiss-Prot: SH3G1_HUMAN, Q99961
Tissue specificity: Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and
uterus

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for SH3GL1 gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	SH3GL1¹	--	SH3-domain GRB2-like 1	89.55(n) 95.2(a)	485039 XM_863414.1 XP_868507.1
chimpanzee (Pan troglodytes)	SH3GL1¹	--	SH3-domain GRB2-like 1	88.14(n) 84.18(a)	738129 XM_001138821.1 XP_001138821.1
cow (Bos taurus)	SH3GL1¹	--	SH3-domain GRB2-like 1	91.85(n) 97.01(a)	512719 NM_001046130.1 NP_001039595.1
mouse (Mus musculus)	Sh3gl1^{1, 5}	17 (35.00 cM)⁵	SH3-domain GRB2-like 1^{1, 5}	87.95(n)¹ 94.02(a)¹	20405¹ NM_013664.2¹ NP_038692.1¹ AK154836⁵ AK162715⁵ (see all 13)
chicken (Gallus gallus)	SH3GL1¹	--	SH3-domain GRB2-like 1	83.11(n) 91.55(a)	395202 NM_204529.1 NP_989860.1

About this table Species with no ortholog for SH3GL1

ENSEMBL Gene Tree for SH3GL1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for SH3GL1 gene

SH3GL3² SH3GL2²

Pseudogenes

3 related pseudogenes

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/185 NCBI SNPs in SH3GL1 are shown (see all 185 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 64)

AB	SNP ID	Valid	Chr 19 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
--	rs11322^1,2	A,F	4311627(+)	`ATGTCG/AGGGCT`	1	--	ut3¹ ese³		1	MN	184
--	rs243261^1,2	A,C,F	4313691(+)	`GGCTTG/CGGCTT`	1	P/P	syn¹		3	MN NA	444
	rs243404^1,2	A,C,F,H,O	4335674(-)	`AGAGTC/TTCCAA`	1	--	int¹		21	NA EA MN EU WA	2165
	rs73234^1,2	A,C,F,H,O	4345310(+)	`CTAGCC/GGCATT`	1	--	int¹		15	NA EA MN EU WA	2942
	rs2247205^1,2	C,F,H,O	4342485(-)	`AGTTCG/AGCTAA`	1	--	int¹		7	EA EU WA	2082
	rs11085073^1,2	A,C,F,H	4326162(+)	`GGTGCG/AAGGCT`	1	--	int¹		4	EU EA WA	416
	rs107288^1,2	A,C,F,H	4316397(+)	`GCACAC/TGCAGG`	1	--	int¹		7	EA EU WA	1534
	rs11085074^1,2	A,C,F,H	4337352(+)	`GGGCAA/GAGTCC`	1	--	int¹		12	EA NA EU WA	986
	rs1882930^1,2	C,H,O	4330805(+)	`AGCACG/ACCGCT`	1	--	int¹		11	NA EA MN EU WA	1110
	rs7257209^1,2	C,F,H	4323656(+)	`CAACAC/TCTGGG`	1	--	int¹		4	EU EA WA	418

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HapMap Linkage Disequilibrium images for SH3GL1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 601768 disorders: 601626

UniProtKB/Swiss-Prot: SH3G1_HUMAN, Q99961

In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN

fusion gene

1 Novoseek disease relationship for SH3GL1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
leukemogenesis	76.29	5	16990610 (2), 14551139 (1), 15077184 (1)

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(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/24 PubMed articles for SH3GL1 gene (see all 24 ):

A novel SH3-containing human gene family preferentially expressed in the central nervous system. (PubMed id 9169142)^{2, 3, 4} Giachino C....Migone N. (1997)
EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia. (PubMed id 9122235)^{1, 3, 4} So C.W.... Chan L.C. (1997)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The SH3 domains of endophilin and amphiphysin bind to the proline- rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity. (PubMed id 10542231)^{3, 4} Cestra G.... Cesareni G. (1999)
Functional contribution of EEN to leukemogenic transformation by MLL-EEN fusion protein. (PubMed id 15077184)^{1, 3} Liu H....Chen S.J. (2004)
Activation of EGF receptor endocytosis and ERK1/2 signaling by BPGAP1 requires direct interaction with EEN/endophilin II and a functional RhoGAP domain. (PubMed id 15944398)^{1, 3} Lua B.L. and Low B.C. (2005)
Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein. (PubMed id 14551139)^{1, 3} Yam J.W.... Chan L.C. (2004)
Phosphoproteome of resting human platelets. (PubMed id 18088087)⁴ Zahedi R.P.... Sickmann A. (2008)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)⁴ Dephoure N.... Gygi S.P. (2008)
Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry. (PubMed id 17287340)⁴ Molina H.... Pandey A. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 6455	HGNC: 10830	AceView: SH3GL1	Ensembl:ENSG00000141985	euGenes: HUgn6455
ECgene: SH3GL1	H-InvDB: SH3GL1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for SH3GL1	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for SH3GL1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for SH3GL1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for SH3GL1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for SH3GL1		Antibodies for SH3GL1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for SH3GL1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
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	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (pan Endophilin, SH3 containing Grb 2 like 1 protein)
	Antibodies (pan Endophilin, SH3 containing Grb 2 like 1 protein)

	Tagged/untagged cDNA clones
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	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for SH3GL1

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Antibodies for SH3GL1

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SH3GL1 Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for SH3GL1

Summaries
for SH3GL1

Genomic Location
for SH3GL1

Proteins
for SH3GL1

Protein Domains/
Families
for SH3GL1

Gene Function
for SH3GL1

Pathways & Interactions
for SH3GL1

Drugs & Compounds
for SH3GL1

Transcripts
for SH3GL1

Expression
for SH3GL1

Orthologs
for SH3GL1

Paralogs
for SH3GL1

SNPs/Variants
for SH3GL1

Disorders & Mutations
for SH3GL1

Medical News
for SH3GL1

Publications
for SH3GL1

Search for SH3GL1

Genome Databases showing SH3GL1

Other Databases showing SH3GL1

Specialized Databases showing SH3GL1

Licensable Technologies
for SH3GL1

Services
for SH3GL1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

SH3GL1 Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor SH3GL1

Summariesfor SH3GL1

Genomic Locationfor SH3GL1

Proteinsfor SH3GL1

Protein Domains/Familiesfor SH3GL1

Gene Functionfor SH3GL1

Pathways & Interactionsfor SH3GL1

Drugs & Compoundsfor SH3GL1

Transcriptsfor SH3GL1

Expression for SH3GL1

Orthologsfor SH3GL1

Paralogsfor SH3GL1

SNPs/Variantsfor SH3GL1

Disorders & Mutationsfor SH3GL1

Medical Newsfor SH3GL1

Publicationsfor SH3GL1

Search for SH3GL1

Genome Databases showing SH3GL1

Other Databases showing SH3GL1

Specialized Databases showing SH3GL1

Licensable Technologiesfor SH3GL1

Servicesfor SH3GL1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for SH3GL1

Summaries
for SH3GL1

Genomic Location
for SH3GL1

Proteins
for SH3GL1

Protein Domains/
Families
for SH3GL1

Gene Function
for SH3GL1

Pathways & Interactions
for SH3GL1

Drugs & Compounds
for SH3GL1

Transcripts
for SH3GL1

Expression
for SH3GL1

Orthologs
for SH3GL1

Paralogs
for SH3GL1

SNPs/Variants
for SH3GL1

Disorders & Mutations
for SH3GL1

Medical News
for SH3GL1

Publications
for SH3GL1

Licensable Technologies
for SH3GL1

Services
for SH3GL1