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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SH3D19 Gene

protein-coding   GIFtS: 53
GCID: GC04M152041

SH3 domain containing 19
 Explore 5 diseases affiliated with
SH3D19 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SH3D19    

Aliases
for SH3D19 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
SH3 Domain Containing 191 2     ADAM-Binding Protein Eve-12 3
EBP1 2 3 5     EEN-Binding Protein2 3
EVE11 2     DKFZp434D02151
Kryn1 2     SH3 Domain Protein D192
SH3P191 2     SH3 Domain-Containing Protein 192

External Ids:    HGNC: 304181   Entrez Gene: 1525032   Ensembl: ENSG000001096867   OMIM: 6086745   UniProtKB: Q5HYK73   

Export aliases for SH3D19 gene to outside databases

Previous GC identifers: GC04M152401 GC04M152260 GC04M147766


Summaries
for SH3D19 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SH3D19:
This gene encodes a multiple SH3 domain-containing protein, which interacts with other proteins, such as EBP and
members of ADAM family, via the SH3 domains. This protein may be involved in suppression of Ras-induced cellular
transformation and Ras-mediated activation of ELK1 by EBP, and regulation of ADAM proteins in the signaling of
EGFR-ligand shedding. Alternatively spliced transcript variants encoding different isoforms have been found for this
gene. (provided by RefSeq, Aug 2011)

UniProtKB/Swiss-Prot: SH319_HUMAN, Q5HYK7
Function: May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand
shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1.
Plays a role in the regulation of cell morphology and cytoskeletal organization




Genomic Views
for SH3D19 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SH3D19 gene promoter:
         HFH-3   AP-1   GATA-3   MEF-2A   FOXI1   POU2F1   POU2F1a   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SH3D19 promoter sequence
   Search SABiosciences Chromatin IP Primers for SH3D19

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SH3D19


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q31.3   Ensembl cytogenetic band:  4q31.3   HGNC cytogenetic band: 4q31.3

SH3D19 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SH3D19 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M152041:  view genomic region     (about GC identifiers)

Start:
 152,041,431 bp from pter      End:
 152,149,182 bp from pter
Size:
 107,752 bases      Orientation:
 minus strand

Proteins
for SH3D19 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SH319_HUMAN, Q5HYK7 (See protein sequence)
Recommended Name: SH3 domain-containing protein 19  
Size: 790 amino acids; 86525 Da
Subunit: Interacts with ADAM12. Isoform 4 and isoform 5 (but not isoform 1 and isoform 2) interact with ADAM9, ADAM10,
ADAM15 and ADAM17. Interacts with SH3GL1 SH3 domain. Interacts via SH3 3 and SH3 4 or SH3 4 and SH3 5 domains with
SOS2. Probably forms a trimeric complex with SH3GL1 and SOS2. Interacts with SH3YL1 (By similarity)
Subcellular location: Cytoplasm. Nucleus. Note=Is recruited to the nucleus by the MLL-EEN fusion protein;
Caution: It is uncertain whether Met-1 or Met-4 is the initiator
Sequence caution: Sequence=AAI08891.1; Type=Erroneous initiation; Sequence=AAI08892.1; Type=Erroneous initiation;
Sequence=AAI08893.1; Type=Erroneous initiation; Sequence=AAI08894.1; Type=Erroneous initiation; Sequence=BAF83714.1;
Type=Erroneous initiation; Sequence=CAI46052.1; Type=Erroneous initiation;
Secondary accessions: B7Z296 Q08EK1 Q32N10 Q5U3B8 Q86XB3 Q8N5E7 Q9UFC8
Alternative splicing: 5 isoforms:  Q5HYK7-1   Q5HYK7-2   Q5HYK7-3   Q5HYK7-4   Q5HYK7-5   

Explore the universe of human proteins at neXtProt for SH3D19: NX_Q5HYK7

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q5HYK7

    • SH3D19 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (4 alternative transcripts): 
    NP_001009555.3  NP_001122395.1  NP_001122396.1  NP_001230278.1  

    ENSEMBL proteins: 
     ENSP00000387030   ENSP00000386848   ENSP00000423449   ENSP00000302913   ENSP00000416708  
     ENSP00000404542   ENSP00000415694  
    Reactome Protein details: Q5HYK7
    Human Recombinant Protein Products: 
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    Novus Biologicals SH3D19 Proteins
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SH3D19

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005794Golgi apparatus IDA--
    GO:0005829cytosol TAS--
    GO:0005886plasma membrane IDA15280379


    SH3D19 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for SH3D19

    Protein Domains /
    Families
    for SH3D19 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SH3D19 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR011511 SH3_2
     IPR000108 p67phox
     IPR001452 SH3_domain

    Graphical View of Domain Structure for InterPro Entry Q5HYK7

    ProtoNet protein and cluster: Q5HYK7

    2 Blocks protein families:
    IPB000108 Neutrophil cytosol factor 2 signature
    IPB011511 Variant SH3


    UniProtKB/Swiss-Prot: SH319_HUMAN, Q5HYK7
    Similarity: Contains 5 SH3 domains


    Function
    for SH3D19 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SH319_HUMAN, Q5HYK7
    Function: May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand
    shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1.
    Plays a role in the regulation of cell morphology and cytoskeletal organization

    miRNA
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    hsa-mir-218 (MIRT001061)

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    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate SH3D19 (see all 25):
    hsa-miR-25 hsa-miR-219-5p hsa-miR-301a hsa-miR-1297 hsa-miR-511 hsa-miR-4325 hsa-miR-3613-3p hsa-miR-3662
    SwitchGear 3'UTR luciferase reporter plasmid: SH3D19 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI15280379
    GO:0070064proline-rich region binding IPI15280379


    SH3D19 for ontologies           About GeneDecksing



    Pathways & Interactions
    for SH3D19 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Clathrin derived vesicle budding
    		trans-Golgi Network Vesicle Budding1.00
    		Golgi Associated Vesicle Biogenesis0.89
    		Clathrin derived vesicle budding1.00
    2Membrane Trafficking
    		Membrane Trafficking1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    4        Reactome Pathways for SH3D19
        Membrane Trafficking
    Clathrin derived vesicle budding
    Golgi Associated Vesicle Biogenesis
    trans-Golgi Network Vesicle Budding



    SH3D19 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SH3D19

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/28 Interacting proteins for SH3D19 (Q5HYK72, 3 ENSP000003029134) via UniProtKB, MINT, STRING, and/or I2D (see all 28)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ADAM12O431842, 3, ENSP000003576684MINT-56613 MINT-56611 MINT-56614 MINT-56612 I2D: score=2 STRING: ENSP00000357668
    SH3YL1Q96HL83, ENSP000004041434I2D: score=3 STRING: ENSP00000404143
    ADAM15Q134443, ENSP000003494364I2D: score=1 STRING: ENSP00000349436
    SH3GL1Q999613, ENSP000002698864I2D: score=1 STRING: ENSP00000269886
    SH3GL3Q999633, ENSP000003913724I2D: score=1 STRING: ENSP00000391372
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006892post-Golgi vesicle-mediated transport TAS--
    GO:0007010cytoskeleton organization IMP--
    GO:0016044cellular membrane organization TAS--
    GO:0022604regulation of cell morphogenesis IMP--
    GO:0051044positive regulation of membrane protein ectodomain proteolysis IMP15280379


    SH3D19 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SH3D19 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SH3D19
    Search CenterWatch for drugs/clinical trials and news about SH3D19 / SH319 

    Transcripts
    for SH3D19 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SH3D19 gene (4 alternative transcripts): 
    NM_001009555.3  NM_001128923.1  NM_001128924.1  NM_001243349.1  

    Unigene Cluster for SH3D19:

    SH3 domain containing 19
    Hs.567725  [show with all ESTs]
    Unigene Representative Sequence: NM_001009555
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000409598(uc003ime.2) ENST00000409252 ENST00000478503(uc003imb.2)
    ENST00000514152(uc010ipm.2) ENST00000508492 ENST00000462257 ENST00000474743
    ENST00000514013 ENST00000304527(uc010ipl.1) ENST00000455740 ENST00000424281(uc003imc.2)
    ENST00000427414

    miRNA
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    hsa-miR-25 hsa-miR-219-5p hsa-miR-301a hsa-miR-1297 hsa-miR-511 hsa-miR-4325 hsa-miR-3613-3p hsa-miR-3662
    SwitchGear 3'UTR luciferase reporter plasmid: SH3D19 3' UTR sequence
    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    AK092528.1 AK291025.1 AK294476.1 AL133047.1 BC010110.2 BC032404.1 BC032468.1 BC045742.1 
    BC085613.1 BC108890.1 BC108891.1 BC108892.1 BC108893.1 BX647422.1 X75686.1 

    16 DOTS entries:

    DT.100766894  DT.447448  DT.100766893  DT.91747954  DT.95215662  DT.314078  DT.100766899  DT.121223162 
    DT.100844768  DT.121223168  DT.121223370  DT.121223487  DT.40287723  DT.40281546  DT.91986500  DT.95276332 

    24/195 AceView cDNA sequences (see all 195):

    AA598669 CR593109 CK903666 BC010110 AI802284 BU508639 AI014258 W68646 
    BF109395 AW009340 BI963947 AK128493 BX405733 AA307462 CN478737 CD675494 
    CD699913 BM831166 AA610281 AA385529 BM806268 BX504483 CD673790 AA447454 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for SH3D19 (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19 ^
    SP1:              -                                                     -     -                                         -                                       
    SP2:                                                                                                                    -                                       
    SP3:                                                                                                                                                            
    SP4:                                                                    -     -     -                                   -                                       
    SP5:              -                             -                                                                                                               

    ExUns: 20 ^ 21 ^ 22 ^ 23
    SP1:                        
    SP2:                        
    SP3:                        
    SP4:                        
    SP5:                        


    ECgene alternative splicing isoforms for SH3D19

    Expression
    for SH3D19 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SH3D19 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGGTATATAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SH3D19 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    CartilageLumbar Intervertebral DiscCartilage
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See SH3D19 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SH3D19

    SOURCE GeneReport for Unigene cluster: Hs.567725

    UniProtKB/Swiss-Prot: SH319_HUMAN, Q5HYK7
    Tissue specificity: Widely expressed with highest levels in heart, skeletal muscle, kidney, liver, placenta, small
    intestine and lung. Expressed at low levels in colon, thymus, spleen and leukocytes

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    In Situ
    Assay Products:     
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    Orthologs
    for SH3D19 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for SH3D19 gene from 5/15 species (see all 15)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SH3D191 SH3 domain containing 19 66.62(n)
    58.52(a)    		   422478  XM_420444.3  XP_420444.3 
    lizard
    (Anolis carolinensis)    		 Reptilia SH3D196
    		 --
    		 54(a)
    		 1 ↔ 1
    		 5(132498168-132528492)
    zebrafish
    (Danio rerio)    		 Actinopterygii sh3d191 SH3 domain containing 19 48.27(n)
    38.37(a)    		   553811  NM_001020773.1  NP_001018609.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta l(3)058226
    		 lethal (3) 05822
    		 13(a)
    		 1 ↔ 1
    		 3R(14114579-14124606)
    worm
    (Caenorhabditis elegans)    		 Secernentea B0303.71 Protein B0303.7 42.95(n)
    29.07(a)    		   176220  NM_066517.5  NP_498918.3 


    ENSEMBL Gene Tree for SH3D19 (if available)
    TreeFam Gene Tree for SH3D19 (if available) 

    Paralogs
    for SH3D19 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SH3D19 gene
    SH3RF32  SH3RF22  SORBS32  SH3RF12  SORBS12  SORBS22  
    5 SIMAP similar genes for SH3D19 using alignment to 2 protein entries:     SH319_HUMAN (see all proteins):
    SH3GL1    SH3GL2    GRAP2    ARHGEF7    ITSN1

    SH3D19 for paralogs           About GeneDecksing



    Genomic Variants
    for SH3D19 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for SH3D19
         2 CNVs: 34438 92457
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SH3D19
    DNA2.0 Custom Variant and Variant Library Synthesis for SH3D19

    Disorders / Diseases
    for SH3D19 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SH3D19 for disorders           About GeneDecksing

    OMIM gene information: 608674    OMIM disorders: --

    5 diseases for SH3D19:    About MalaCards
    wiskott-aldrich syndrome    acute myeloid leukemia    myeloid leukemia    microphthalmia
    leukemia


    Export disorders for SH3D19 gene to outside databases

    Publications
    for SH3D19 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SH3D19 gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with SH3D19)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. ADAM binding protein Eve-1 is required for ectodomain shedding of epidermal growth factor receptor ligands. (PubMed id 15280379)1, 2 Tanaka M....Higashiyama S. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein. (PubMed id 14551139)1, 2 Yam J.W.... Chan L.C. (2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    5. Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration. (PubMed id 21834987)2 Bai S.W.... Ridley A.J. (2011)
    6. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
    7. Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
    8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    9. Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS. (PubMed id 19531213)1 Havrylov S....Redowicz M.J. (2009)
    10. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)

    External Searches for SH3D19 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SH3D19 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 152503 HGNC: 30418 AceView: DKFZp434D0215 Ensembl:ENSG00000109686 euGenes: HUgn152503
    ECgene: SH3D19 H-InvDB: SH3D19

    Other Databases showing SH3D19 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SH3D19 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SH3D19 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SH3D19 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SH3D19 gene:
    Search GeneIP for patents involving SH3D19

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
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