Aliases for SH3BP5 Gene
External Ids for SH3BP5 Gene
Previous GeneCards Identifiers for SH3BP5 Gene
GeneCards Summary for SH3BP5 Gene
SH3BP5 (SH3-Domain Binding Protein 5 (BTK-Associated)) is a Protein Coding gene. Diseases associated with SH3BP5 include chromosome 1q deletion and tabes dorsalis. Among its related pathways are B cell receptor signaling pathway (KEGG). GO annotations related to this gene include SH3 domain binding and protein kinase inhibitor activity. An important paralog of this gene is SH3BP5L.
UniProtKB/Swiss-Prot for SH3BP5 Gene
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.