SH3BP2 Gene
protein-coding GIFtS: 56
GCID: GC04P002831
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|
SH3-domain binding protein 2(Previous name: Cherubism )
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Aliases
for SH3BP2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SH3-Domain Binding Protein 21 2 | | Cherubism1 | | CRBM1 2 | | RES4-231 | | 3BP-22 3 | | Abl-SH3 Binding Protein 22 | | 3BP22 3 | | SH3 Domain-Binding Protein 22 | | CRPM2 5 | | TNFAIP3 Interacting Protein 22 |
Export aliases for SH3BP2 gene to outside databasesPrevious GC identifers: GC04P002783 GC04M9I0057 GC04P002826 GC04P002851 |
Summaries
for SH3BP2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SH3BP2:
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region,and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYKprotein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptionalactivity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multipletranscript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Mar 2009)
UniProtKB/Swiss-Prot: 3BP2_HUMAN, P78314Function: Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds tophosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylationdependent mechanism
|
Genomic Views
for SH3BP2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_006051.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SH3BP2 gene promoter:
NCX/Ncx RelA AP-2gamma NF-kappaB HEN1 STAT3 ARP-1 Cart-1 NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SH3BP2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SH3BP2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4p16.3 Ensembl cytogenetic band: 4p16.3 HGNC cytogenetic band: 4p16.3SH3BP2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P002831: view genomic region
(about GC identifiers)
Start:
|
2,794,750 bp from pter |
End:
|
2,842,825 bp from pter |
Size:
|
48,076 bases |
Orientation:
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plus strand |
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Proteins
for SH3BP2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: 3BP2_HUMAN, P78314 (See
protein sequence)Recommended Name: SH3 domain-binding protein 2 Size: 561 amino acids; 62244 Da
2 PDB 3D structures from  and Proteopedia  for SH3BP2:2CR4 (3D)
3TWR (3D)
Secondary accessions: A6NNC2 B2R5R6 B4DT04 D3DVR0 O00500 O15373 P78315Alternative splicing: 3 isoforms: P78314-1 P78314-2 P78314-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SH3BP2: NX_P78314
Post-translational modifications:
Phosphorylated. Phosphorylation at Tyr-448 may stimulate the activity of the LYN kinase (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P78314
SH3BP2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001116153.1 NP_001139327.1 NP_001139328.1 NP_003014.3
ENSEMBL proteins: ENSP00000409746 ENSP00000422796 ENSP00000423275 ENSP00000424917 ENSP00000424072 ENSP00000424105 ENSP00000423823 ENSP00000425537 ENSP00000403231 ENSP00000424846 ENSP00000422605 ENSP00000348685 ENSP00000426818 ENSP00000388152 ENSP00000422168 ENSP00000374488
Human Recombinant Protein Products:
SH3BP2 Antibody Products:
Assay Products for SH3BP2: |
Protein
Domains /
Families
for SH3BP2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SH3BP2 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P78314ProtoNet protein and cluster: P78314 1 Blocks protein family: IPB001849 Pleckstrin-like
UniProtKB/Swiss-Prot: 3BP2_HUMAN, P78314Similarity: Contains 1 PH domainSimilarity: Contains 1 SH2 domain |
Function
for SH3BP2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: 3BP2_HUMAN, P78314Function: Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds tophosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylationdependent mechanism Genatlas biochemistry entry for SH3BP2:Src homology domain 3 (SH3) binding protein BP2,mouse homolog within a common region of deletion in bladder carcinoma
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SH3BP2 (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SH3BP2 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for SH3BP2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SH3BP2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3BP2 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
SH3BP2 for ontologies About GeneDecksing
Animal Models:
Mouse knock-outs for SH3BP2: Sh3bp2tm1Rtpl Sh3bp2tm1Geha
14 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Sh3bp2):
SH3BP2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SH3BP2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | B Cell Receptor Signaling Pathway | | | 2 | Natural killer cell mediated cytotoxicity | | | 3 | TCR signaling in naive CD4+ T cells | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for SH3BP2
1 
Kegg Pathway (Kegg details for SH3BP2):
SH3BP2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SH3BP2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/33 Interacting proteins for SH3BP2 (P783141, 2, 3 ENSP000003486854) via UniProtKB, MINT, STRING, and/or I2D (see all 33)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table
SH3BP2 for ontologies About GeneDecksing
|
Drugs & Compounds
for SH3BP2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SH3BP2
Search CenterWatch for drugs/clinical trials and news about SH3BP2 / 3BP2
|
Transcripts
for SH3BP2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SH3BP2 gene (4 alternative transcripts): NM_001122681.1 NM_001145855.1 NM_001145856.1 NM_003023.4 Unigene Cluster for SH3BP2: SH3-domain binding protein 2 Hs.167679 [show with all ESTs]Unigene Representative Sequence: NM_00114585518/30 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 30): ENST00000452765 ENST00000503219 ENST00000512131 ENST00000510193 ENST00000511237
ENST00000510074 ENST00000504294 ENST00000508385 ENST00000513020 ENST00000511663(uc010icn.2)
ENST00000512014 ENST00000513095 ENST00000502260 ENST00000511185 ENST00000435136
ENST00000508338 ENST00000511747 ENST00000509677
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SH3BP2 (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SH3BP2 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): SH3BP2 (NM_003023) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SH3BP2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SH3BP2 |
Additional cDNA sequence: AB000462.1 AF000936.1 AK124073.1 AK225497.1 AK299996.1 AK307106.1 AK312286.1 BC022996.1 L37198.1 U56386.1 21 DOTS entries: DT.97801635 DT.454424 DT.100761526 DT.95111500 DT.95111475 DT.100761523 DT.121232491 DT.100773501 DT.100761530 DT.92430343 DT.95111470 DT.95344938 DT.100747139 DT.121232473 DT.121232516 DT.121244845 DT.92430341 DT.95352426 DT.97767357 DT.99975478 DT.100761525 24/187 AceView cDNA sequences (see all 187): CF456690 AK124073 CB851004 T39472 AW451700 BG562732 AA490488 BU632158 CA487534 CR619042 BE222743 CA436871 BM669593 BM715322 AW469668 BM973429 CF887402 AI424336 AW449314 AW292318 BU680159 BX505033 AU133371 BE465238
GeneLoc Exon Structure
5/25 Alternative Splicing Database (ASD) splice patterns (SP) for SH3BP2 (see all 25) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16 | ^ | 17a | · | 17b | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | | | - | | |
| SP3: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | - | | | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | | | | | | | | | - | | | | - | |
| ExUns: | 17c | · | 17d | ^ | 18 | ^ | 19a | · | 19b | · | 19c | · | 19d | ^ | 20a | · | 20b | · | 20c | ^ | 21a | · | 21b | · | 21c | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26a | · | 26b | ^ | 27a | · | 27b | ^ | 28 |
|---|
|
| SP1: | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | |
| SP2: | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | |
| SP3: | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | |
| SP5: | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SH3BP2
|
Expression
for SH3BP2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SH3BP2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGAGGGTGAG
About this image
See SH3BP2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SH3BP2
SOURCE GeneReport for Unigene cluster: Hs.167679
UniProtKB/Swiss-Prot: 3BP2_HUMAN, P78314Tissue specificity: Expressed in a variety of tissues including lung, liver, skeletal muscle, kidney and pancreas
SABiosciences Custom PCR Arrays for SH3BP2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SH3BP2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SH3BP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SH3BP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SH3BP2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3BP2 |
Orthologs
for SH3BP2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for SH3BP2 gene from 4/13 species (see all 13) About this table
ENSEMBL Gene Tree for SH3BP2 (if available)
TreeFam Gene Tree for SH3BP2 (if available) |
Paralogs
for SH3BP2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SH3BP2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for SH3BP2
3 CNVs: 51374 30193 30194
Human Gene Mutation Database (HGMD): SH3BP2
| SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for SH3BP2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SH3BP2 for disorders About GeneDecksing
OMIM gene information: 602104
OMIM disorders: 118400
UniProtKB/Swiss-Prot: 3BP2_HUMAN, P78314
Defects in SH3BP2 are the cause of cherubism (CRBM) [MIM:118400]. CRBM is an autosomal dominant inheritedsyndrome characterized by excessive bone degradation of the upper and lower jaws, which often begins around threeyears of age. It is followed by development of fibrous tissue masses, which causes a characteristic facial swelling
10  diseases for SH3BP2: About MalaCardscherubism giant cell reparative granuloma root resorption bladder carcinoma
huntington's disease neurofibromatosis hepatitis b hepatitis
carcinoma leukemia
3 diseases from the University of Copenhagen DISEASES database for SH3BP2:Cherubism Giant cell reparative granuloma Root resorption 3 Novoseek disease relationships for SH3BP2 gene About this table
GeneTests: SH3BP2
Cherubism
Human Genome Epidemiology (HuGE) Navigator: SH3BP2 (2 documents)
Export disorders for SH3BP2 gene to outside databases
|
Publications
for SH3BP2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SH3BP2 gene, integrated from 9 sources (see all 60):
(articles sorted by number of sources associating them with SH3BP2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mutations in the gene encoding c-Abl-binding protein SH3BP2 cause cherubism. (PubMed id 11381256)1, 2, 3, 9 Ueki Y....Reichenberger E. (2001)
- Identification and characterization of the human homologue of SH3BP2, an SH3 binding domain protein within a common region of deletion at 4p16.3 involved in bladder cancer. (PubMed id 9299232)1, 2, 3 Bell S.M.... Knowles M.A. (1997)
- A missense mutation in the SH3BP2 gene on chromosome 4p16.3 found in a case of nonfamilial cherubism. (PubMed id 14577811)1, 2, 9 Imai Y....Yamada A. (2003)
- Novel mutation in the gene encoding c-Abl-binding protein SH3BP2 causes cherubism. (PubMed id 12900899)1, 2, 9 Lo B....Teebi A.S. (2003)
- An unappreciated role for RNA surveillance. (PubMed id 14759258)1, 2 Hillman R.T.... Brenner S.E. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The primary structure and genomic organization of five novel transcripts located close to the Huntington's disease gene on human chromosome 4p16.3. (PubMed id 9734812)1, 2 Hadano S.... Ikeda J.-E. (1998)
- Tyrosine phosphorylation of 3BP2 regulates B cell rec eptor-mediated activation of NFAT. (PubMed id 19833725)1, 9 Shukla U....Sada K. (2009)
- [Gene mutation and expression of SH-3BP-2 in cherubis m] (PubMed id 19576004)1, 9 Li Y.W....Gao P. (2009)
- The adaptor protein 3BP2 binds human CD244 and links this receptor to Vav signaling, ERK activation, and NK cell killing. (PubMed id 16177062)1, 9 Saborit-Villarroya I....Martin M. (2005)
|
External Searches for SH3BP2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SH3BP2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SH3BP2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SH3BP2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for SH3BP2 gene:
Search GeneIP for patents involving SH3BP2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SH3BP2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SH3BP2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SH3BP2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SH3BP2 | | | OriGene Protein Over-expression Lysate for SH3BP2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SH3BP2 | | OriGene 3'-UTR Clone for SH3BP2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SH3BP2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SH3BP2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SH3BP2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SH3BP2 | | OriGene Custom Protein Services for SH3BP2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SH3BP2 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SH3BP2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SH3BP2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SH3BP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SH3BP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SH3BP2 |
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| | | | Search Tocris compounds for SH3BP2 |
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 | | | SH3BP2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3BP2 |
|  |  |  | | | | Search ThermoFisher Antibodies for SH3BP2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SH3BP2 |
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