Aliases for SH3BP1 Gene
External Ids for SH3BP1 Gene
GeneCards Summary for SH3BP1 Gene
SH3BP1 (SH3-Domain Binding Protein 1) is a Protein Coding gene. GO annotations related to this gene include GTPase activator activity and SH3 domain binding. An important paralog of this gene is SRGAP3.
UniProtKB/Swiss-Prot for SH3BP1 Gene
Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity).